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Acute coagulopathy of trauma: Mechanism, identification and effect
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Brohi K, Cohen MJ, Davenport RA. Acute coagulopathy of trauma: mechanism, identification and effect. Curr Opin Crit Care 2007;13:680-5.
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Acute coagulopathy of trauma: Hypoperfusion induces systemic anticoagulation and hyperfibrinolysis
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discussion 1217
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Brohi K, Cohen MJ, Ganter MT, Schultz MJ, Levi M, Mackersie RC, Pittet JF. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma 2008;64:1211-7; discussion 1217.
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Floccard B, Rugeri L, Faure A, Denis MS, Boyle EM, Peguet O, Levrat A, Guillaume C, Marcotte G, Vulliez A, Hautin E, David JS, Negrier C, Allaouchiche B. Early coagulopathy in trauma patients: an on-scene and hospital admission study. Injury 2012;43:26-32.
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Activated Protein C is a principal mediator of acute traumatic coagulopathy
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Davenport R, Rourke C, Manson J, De'Ath H, Platton S, Coates A, Hart D, Pearse R, Pasi JK, Stanworth S, Brohi K. Activated Protein C is a principal mediator of acute traumatic coagulopathy. Abstract (oral) presentation, International Society of Thrombosis & Haemostasis. 2011.
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Abstract (Oral) Presentation, International Society of Thrombosis & Haemostasis
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Davenport, R.1
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84855826297
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Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients
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Cohen MJ, Call M, Nelson M, Calfee CS, Esmon CT, Brohi K, Pittet JF. Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients. Ann Surg 2012;255:379-85.
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The coagulopathy of trauma: A review of mechanisms
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Hess JR, Brohi K, Dutton RP, Hauser CJ, Holcomb JB, Kluger Y, Mackway-Jones K, Parr MJ, Rizoli SB, Yukioka T, Hoyt DB, Bouillon B. The coagulopathy of trauma: a review of mechanisms. J Trauma 2008;65:748-54.
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7
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Functional definition and characterization of acute traumatic coagulopathy
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Davenport R, Manson J, De'Ath H, Platton S, Coates A, Allard S, Hart D, Pearse R, Pasi KJ, MacCallum P, Stanworth S, Brohi K. Functional definition and characterization of acute traumatic coagulopathy. Crit Care Med 2011;39: 2652-8.
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8
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Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: Experience with 1974 consecutive trauma patients
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Holcomb JB, Minei KM, Scerbo ML, Radwan ZA, Wade CE, Kozar RA, Gill BS, Albarado R, McNutt MK, Khan S, Adams PR, McCarthy JJ, Cotton BA. Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg 2012;256:476-86.
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9
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77956487533
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Definition and drivers of acute traumatic coagulopathy: Clinical and experimental investigations
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Frith D, Goslings JC, Gaarder C, Maegele M, Cohen MJ, Allard S, Johansson PI, Stanworth S, Thiemermann C, Brohi K. Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations. J Thromb Haemost 2010;8:1919-25.
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Management of major trauma haemorrhage: Treatment priorities and controversies
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Davenport R, Khan S. Management of major trauma haemorrhage: treatment priorities and controversies. Br J Haematol 2011;155:537-48.
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Disseminated intravascular coagulopathy in the first 24 hours after trauma: The association between ISTH score and anatomopathologic evidence
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Rizoli S, Nascimento B Jr, Key N, Tien HC, Muraca S, Pinto R, Khalifa M, Plotkin A, Callum J. Disseminated intravascular coagulopathy in the first 24 hours after trauma: the association between ISTH score and anatomopathologic evidence. J Trauma 2011;71:S441-7.
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Rizoli SB, Scarpelini S, Callum J, Nascimento B, Mann KG, Pinto R, Jansen J, Tien HC. Clotting factor deficiency in early trauma-associated coagulopathy. J Trauma 2011;71: S427-34.
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Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock
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Kozar RA, Peng Z, Zhang R, Holcomb JB, Pati S, Park P, Ko TC, Paredes A. Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock. Anesth Analg 2011;112:1289-95.
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Acute traumatic coagulopathy: Initiated by hypoperfusion: Modulated through the protein C pathway?
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Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? Ann Surg 2007;245:812-8.
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Increase in activated protein C mediates acute traumatic coagulopathy in mice
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Chesebro BB, Rahn P, Carles M, Esmon CT, Xu J, Brohi K, Frith D, Pittet JF, Cohen MJ. Increase in activated protein C mediates acute traumatic coagulopathy in mice. Shock 2009;32:659-65.
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A high admission syndecan-1 level, a marker of endothelial glycocalyx degradation, is associated with inflammation, protein C depletion, fibrinolysis, and increased mortality in trauma patients
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Fibrinogen levels during trauma hemorrhage, response to replacement therapy, and association with patient outcomes
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Rourke C, Curry N, Khan S, Taylor R, Raza I, Davenport R, Stanworth S, Brohi K. Fibrinogen levels during trauma hemorrhage, response to replacement therapy, and association with patient outcomes. J Thromb Haemost 2012;10: 1342-51.
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Raza I, Davenport R, Rourke C, Platton S, Manson J, Spoors C, Khan S, De'Ath H, Allard S, Hart D, Pasi J, Hunt B, Stanworth S, MacCallum P, Brohi K. Activation of fibrinolysis in trauma patients without functional lysis on thromboelastometry. J Thromb Haemost. In press 2012.
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