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Volumn 48, Issue 4, 2013, Pages 414-421

17β-Estradiol and genistein acute treatments improve some cerebral cortex homeostasis aspects deteriorated by aging in female rats

Author keywords

17 Estradiol; Aging; Cortical homeostasis; Genistein; GLUT; Rat

Indexed keywords

CYTOCHROME C OXIDASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENISTEIN; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 4;

EID: 84874785765     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.02.010     Document Type: Article
Times cited : (28)

References (62)
  • 1
    • 84860855755 scopus 로고    scopus 로고
    • Neuroprotective role of estrogens: relationship with insulin/IGF-1 signaling
    • Alonso A., Gonzalez C. Neuroprotective role of estrogens: relationship with insulin/IGF-1 signaling. Front. Biosci. 2012, 4:607-619.
    • (2012) Front. Biosci. , vol.4 , pp. 607-619
    • Alonso, A.1    Gonzalez, C.2
  • 3
    • 33751226555 scopus 로고    scopus 로고
    • Regulation of estrogen receptor α by estradiol in pregnant and estradiol treated rats
    • Alonso A., Fernandez R., Ordoñez P., Moreno M., Patterson A.M., González C. Regulation of estrogen receptor α by estradiol in pregnant and estradiol treated rats. Steroids 2006, 71:1052-1061.
    • (2006) Steroids , vol.71 , pp. 1052-1061
    • Alonso, A.1    Fernandez, R.2    Ordoñez, P.3    Moreno, M.4    Patterson, A.M.5    González, C.6
  • 7
    • 0033883022 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators in reproductive medicine and biology
    • Baker V.L., Leitman D., Jaffe R.B. Selective estrogen receptor modulators in reproductive medicine and biology. Obstet. Gynecol. Surv. 2000, 55:S21-S47.
    • (2000) Obstet. Gynecol. Surv. , vol.55
    • Baker, V.L.1    Leitman, D.2    Jaffe, R.B.3
  • 9
    • 80052742071 scopus 로고    scopus 로고
    • Estrogen receptors and the metabolic network
    • Barros R.P., Gustafsson J.Å. Estrogen receptors and the metabolic network. Cell Metab. 2011, 14:289-299.
    • (2011) Cell Metab. , vol.14 , pp. 289-299
    • Barros, R.P.1    Gustafsson, J.Å.2
  • 10
    • 0029842574 scopus 로고    scopus 로고
    • Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats
    • Barzilai N., Rossetti L. Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats. Am. J. Physiol. 1996, 270:E930-E936.
    • (1996) Am. J. Physiol. , vol.270
    • Barzilai, N.1    Rossetti, L.2
  • 11
    • 18144411278 scopus 로고    scopus 로고
    • Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy?
    • Beck V., Rohr U., Jungbauer A. Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy?. J. Steroid Biochem. Mol. Biol. 2005, 94:499-518.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.94 , pp. 499-518
    • Beck, V.1    Rohr, U.2    Jungbauer, A.3
  • 12
    • 0033519422 scopus 로고    scopus 로고
    • Age-related changes of the nucleolar organizer regions without neuron loss in medial mammillary bodies (hypothalamus) in old rats
    • Begega A., Cuesta M., Rubio S., Santín L.J., Arias J.L. Age-related changes of the nucleolar organizer regions without neuron loss in medial mammillary bodies (hypothalamus) in old rats. Mech. Ageing Dev. 1999, 108:113-125.
    • (1999) Mech. Ageing Dev. , vol.108 , pp. 113-125
    • Begega, A.1    Cuesta, M.2    Rubio, S.3    Santín, L.J.4    Arias, J.L.5
  • 13
    • 0026666952 scopus 로고
    • Estrogen induction of cytochrome c oxidase subunit III in rat hippocampus
    • Bettini E., Maggi A. Estrogen induction of cytochrome c oxidase subunit III in rat hippocampus. J. Neurochem. 1992, 58:1923-1929.
    • (1992) J. Neurochem. , vol.58 , pp. 1923-1929
    • Bettini, E.1    Maggi, A.2
  • 14
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 16
    • 0037202286 scopus 로고    scopus 로고
    • Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus
    • Cardona-Gomez G.P., Mendez P., Garcia-Segura L.M. Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus. Brain Res. Mol. Brain Res. 2002, 107:80-88.
    • (2002) Brain Res. Mol. Brain Res. , vol.107 , pp. 80-88
    • Cardona-Gomez, G.P.1    Mendez, P.2    Garcia-Segura, L.M.3
  • 17
    • 26944439050 scopus 로고    scopus 로고
    • Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological implications
    • Chen J.Q., Yager J.D., Russo J. Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological implications. Biochim. Biophys. Acta 2005, 1746:1-17.
    • (2005) Biochim. Biophys. Acta , vol.1746 , pp. 1-17
    • Chen, J.Q.1    Yager, J.D.2    Russo, J.3
  • 18
    • 66049154593 scopus 로고    scopus 로고
    • Gonadal hormones modulate the dendritic spine densities of primary cortical pyramidal neurons in adult female rat
    • Chen J.R., Yan Y.T., Wang T.J., Chen L.J., Wang Y.J., Tseng G.F. Gonadal hormones modulate the dendritic spine densities of primary cortical pyramidal neurons in adult female rat. Cereb. Cortex 2009, 19:2719-2727.
    • (2009) Cereb. Cortex , vol.19 , pp. 2719-2727
    • Chen, J.R.1    Yan, Y.T.2    Wang, T.J.3    Chen, L.J.4    Wang, Y.J.5    Tseng, G.F.6
  • 19
    • 0035074184 scopus 로고    scopus 로고
    • Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex
    • Cheng C.M., Cohen M., Wang J., Bondy C.A. Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex. FASEB J. 2001, 15:907-915.
    • (2001) FASEB J. , vol.15 , pp. 907-915
    • Cheng, C.M.1    Cohen, M.2    Wang, J.3    Bondy, C.A.4
  • 20
    • 0032949905 scopus 로고    scopus 로고
    • Hormones and breast cancer: evidence and implications for consideration of risks and benefits of hormone replacement therapy
    • Colditz G.A. Hormones and breast cancer: evidence and implications for consideration of risks and benefits of hormone replacement therapy. J. Womens Health 1999, 8:347-357.
    • (1999) J. Womens Health , vol.8 , pp. 347-357
    • Colditz, G.A.1
  • 21
    • 33847377682 scopus 로고    scopus 로고
    • Changes in brain oxidative metabolism induced by water maze training
    • Conejo N.M., González-Pardo H., Vallejo G., Arias J.L. Changes in brain oxidative metabolism induced by water maze training. Neuroscience 2007, 145:403-412.
    • (2007) Neuroscience , vol.145 , pp. 403-412
    • Conejo, N.M.1    González-Pardo, H.2    Vallejo, G.3    Arias, J.L.4
  • 22
    • 0034872657 scopus 로고    scopus 로고
    • Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7
    • Diel P., Olff S., Schmidt S., Michna H. Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7. Planta Med. 2001, 67:510-514.
    • (2001) Planta Med. , vol.67 , pp. 510-514
    • Diel, P.1    Olff, S.2    Schmidt, S.3    Michna, H.4
  • 23
    • 0035319913 scopus 로고    scopus 로고
    • Brain glucose transporters; relationship to local energy demand
    • Duelli R., Kuschinsky W. Brain glucose transporters; relationship to local energy demand. News Physiol. Sci. 2001, 16:71-76.
    • (2001) News Physiol. Sci. , vol.16 , pp. 71-76
    • Duelli, R.1    Kuschinsky, W.2
  • 24
    • 0032487335 scopus 로고    scopus 로고
    • Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system
    • El Messari S., Leloup C., Quignon M., Brisorgueil M.J., Penicaud L., Arluison M. Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system. J. Comp. Neurol. 1998, 399:492-512.
    • (1998) J. Comp. Neurol. , vol.399 , pp. 492-512
    • El Messari, S.1    Leloup, C.2    Quignon, M.3    Brisorgueil, M.J.4    Penicaud, L.5    Arluison, M.6
  • 25
    • 0344517349 scopus 로고    scopus 로고
    • Hormone replacement therapy and risk of breast cancer with a favorable histology: results of the Iowa Women's Health Study
    • Gapstur S.M., Morrow M., Sellers T.A. Hormone replacement therapy and risk of breast cancer with a favorable histology: results of the Iowa Women's Health Study. JAMA 1999, 281:2091-2097.
    • (1999) JAMA , vol.281 , pp. 2091-2097
    • Gapstur, S.M.1    Morrow, M.2    Sellers, T.A.3
  • 27
    • 79956007416 scopus 로고    scopus 로고
    • GTx-822, an ER{beta}-selective agonist, protects retinal pigment epithelium (ARPE-19) from oxidative stress by activating MAPK and PI3-K pathways
    • Giddabasappa A., Bauler M.N., Barrett C.M., Coss C.C., Wu Z., Miller D.D., Dalton J.T., Eswaraka J.R. GTx-822, an ER{beta}-selective agonist, protects retinal pigment epithelium (ARPE-19) from oxidative stress by activating MAPK and PI3-K pathways. Invest. Ophthalmol. Vis. Sci. 2010, 51:5934-5942.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 5934-5942
    • Giddabasappa, A.1    Bauler, M.N.2    Barrett, C.M.3    Coss, C.C.4    Wu, Z.5    Miller, D.D.6    Dalton, J.T.7    Eswaraka, J.R.8
  • 28
    • 78649421040 scopus 로고    scopus 로고
    • Developmental regulation of glucose transporters GLUT3, GLUT4 and GLUT8 in the mouse cerebellar cortex
    • Gómez O., Ballester-Lurbe B., Poch E., Mesonero J.E., Terrado J. Developmental regulation of glucose transporters GLUT3, GLUT4 and GLUT8 in the mouse cerebellar cortex. J. Anat. 2010, 217:616-623.
    • (2010) J. Anat. , vol.217 , pp. 616-623
    • Gómez, O.1    Ballester-Lurbe, B.2    Poch, E.3    Mesonero, J.E.4    Terrado, J.5
  • 29
  • 31
    • 0032789522 scopus 로고    scopus 로고
    • Energy intake and utilization vary during development in rats
    • Iossa S., Lionetti L., Mollica M.P., Barletta A., Liverini G. Energy intake and utilization vary during development in rats. J. Nutr. 1999, 129:1593-1596.
    • (1999) J. Nutr. , vol.129 , pp. 1593-1596
    • Iossa, S.1    Lionetti, L.2    Mollica, M.P.3    Barletta, A.4    Liverini, G.5
  • 32
    • 37149015794 scopus 로고    scopus 로고
    • The medial prefrontal cortex is involved in spatial memory retrieval under partial-cue conditions
    • Jo Y.S., Park E.H., Kim I.H., Park S.K., Kim H., Kim H.T., Choi J.-S. The medial prefrontal cortex is involved in spatial memory retrieval under partial-cue conditions. J. Neurosci. 2007, 27:13567-13578.
    • (2007) J. Neurosci. , vol.27 , pp. 13567-13578
    • Jo, Y.S.1    Park, E.H.2    Kim, I.H.3    Park, S.K.4    Kim, H.5    Kim, H.T.6    Choi, J.-S.7
  • 33
    • 57349115353 scopus 로고    scopus 로고
    • Estrogenic control of mitochondrial function and biogenesis
    • Klinge C.M. Estrogenic control of mitochondrial function and biogenesis. J. Cell. Biochem. 2008, 105:1342-1351.
    • (2008) J. Cell. Biochem. , vol.105 , pp. 1342-1351
    • Klinge, C.M.1
  • 35
    • 0034767176 scopus 로고    scopus 로고
    • Effect of aging and obesity on insulin responsiveness and glut-4 glucose transporter content in skeletal muscle of Fischer 344 x Brown Norway rats
    • Larkin L.M., Reynolds T.H., Supiano M.A., Kahn B.B., Halter J.B. Effect of aging and obesity on insulin responsiveness and glut-4 glucose transporter content in skeletal muscle of Fischer 344 x Brown Norway rats. J. Gerontol. A Biol. Sci. Med. Sci. 2001, 56:B486-B492.
    • (2001) J. Gerontol. A Biol. Sci. Med. Sci. , vol.56
    • Larkin, L.M.1    Reynolds, T.H.2    Supiano, M.A.3    Kahn, B.B.4    Halter, J.B.5
  • 36
    • 0036889192 scopus 로고    scopus 로고
    • 17beta-Estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin
    • Linford N.J., Dorsa D.M. 17beta-Estradiol and the phytoestrogen genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin. Steroids 2002, 67:1029-1040.
    • (2002) Steroids , vol.67 , pp. 1029-1040
    • Linford, N.J.1    Dorsa, D.M.2
  • 37
    • 0016271317 scopus 로고
    • Oestrogen effects on brain and pituitary enzyme activities
    • Luine V.N., Khylchevskaya R.I., McEwen B.S. Oestrogen effects on brain and pituitary enzyme activities. J. Neurochem. 1974, 23:925-934.
    • (1974) J. Neurochem. , vol.23 , pp. 925-934
    • Luine, V.N.1    Khylchevskaya, R.I.2    McEwen, B.S.3
  • 39
    • 0038579793 scopus 로고    scopus 로고
    • An oestrogen membrane receptor participates in estradiol actions for the prevention of amyloid-β peptide1-40-induced toxicity in septal-derived cholinergic SN56 cells
    • Marin R., Guerra B., Morales A., Diaz M., Alonso R. An oestrogen membrane receptor participates in estradiol actions for the prevention of amyloid-β peptide1-40-induced toxicity in septal-derived cholinergic SN56 cells. J. Neurochem. 2003, 85:1180-1189.
    • (2003) J. Neurochem. , vol.85 , pp. 1180-1189
    • Marin, R.1    Guerra, B.2    Morales, A.3    Diaz, M.4    Alonso, R.5
  • 40
    • 0036376094 scopus 로고    scopus 로고
    • Estrogen actions throughout the brain
    • McEwen B.S. Estrogen actions throughout the brain. Recent Prog. Horm. Res. 2002, 57:357-384.
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 357-384
    • McEwen, B.S.1
  • 41
    • 0033304765 scopus 로고    scopus 로고
    • Estrogen actions in the central nervous system
    • McEwen B.S., Alves S.H. Estrogen actions in the central nervous system. Endocr. Rev. 1999, 20:279-307.
    • (1999) Endocr. Rev. , vol.20 , pp. 279-307
    • McEwen, B.S.1    Alves, S.H.2
  • 42
    • 1842734654 scopus 로고    scopus 로고
    • Glucose transporter expression in the central nervous system: relationship to synaptic function
    • McEwen B.S., Reagan L.P. Glucose transporter expression in the central nervous system: relationship to synaptic function. Eur. J. Pharmacol. 2004, 490:13-24.
    • (2004) Eur. J. Pharmacol. , vol.490 , pp. 13-24
    • McEwen, B.S.1    Reagan, L.P.2
  • 43
    • 0035912705 scopus 로고    scopus 로고
    • Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation
    • McEwen B., Akama K., Alves S., Brake W.G., Bulloch K., Lee S., Li C., Yuen G., Milner T.A. Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation. PNAS 2001, 98:7093-7100.
    • (2001) PNAS , vol.98 , pp. 7093-7100
    • McEwen, B.1    Akama, K.2    Alves, S.3    Brake, W.G.4    Bulloch, K.5    Lee, S.6    Li, C.7    Yuen, G.8    Milner, T.A.9
  • 45
    • 0021351021 scopus 로고
    • Acute administration of high doses of estrogen increases glucose utilization throughout brain
    • Namba H., Sokoloff L. Acute administration of high doses of estrogen increases glucose utilization throughout brain. Brain Res. 1984, 291:391-394.
    • (1984) Brain Res. , vol.291 , pp. 391-394
    • Namba, H.1    Sokoloff, L.2
  • 46
    • 38449089795 scopus 로고    scopus 로고
    • Estradiol in vivo regulation of brain mitochondrial proteome
    • Nilsen J., Irwin R.W., Gallaher T.K., Brinton R.D. Estradiol in vivo regulation of brain mitochondrial proteome. J. Neurosci. 2007, 27:14069-14077.
    • (2007) J. Neurosci. , vol.27 , pp. 14069-14077
    • Nilsen, J.1    Irwin, R.W.2    Gallaher, T.K.3    Brinton, R.D.4
  • 47
    • 80053059329 scopus 로고    scopus 로고
    • Aging negatively affects estrogens-mediated effects on nitric oxide bioavailability by shifting ERα/ERβ balance in female mice
    • Novensà L., Novella S., Medina P., Segarra G., Castillo N., Heras M., Hermenegildo C., Dantas A.P. Aging negatively affects estrogens-mediated effects on nitric oxide bioavailability by shifting ERα/ERβ balance in female mice. PLoS One 2011, 6:e25335.
    • (2011) PLoS One , vol.6
    • Novensà, L.1    Novella, S.2    Medina, P.3    Segarra, G.4    Castillo, N.5    Heras, M.6    Hermenegildo, C.7    Dantas, A.P.8
  • 48
    • 0021020420 scopus 로고
    • Brain metabolism: a perspective from the blood-brain barrier
    • Pardridge W.M. Brain metabolism: a perspective from the blood-brain barrier. Physiol. Rev. 1983, 63:1481-1535.
    • (1983) Physiol. Rev. , vol.63 , pp. 1481-1535
    • Pardridge, W.M.1
  • 50
    • 81255207179 scopus 로고    scopus 로고
    • Advances in the understanding of the structure and function of ER-α36, a novel variant of human estrogen receptor-alpha
    • Rao J., Jiang X., Wang Y., Chen B. Advances in the understanding of the structure and function of ER-α36, a novel variant of human estrogen receptor-alpha. J. Steroid Biochem. Mol. Biol. 2011, 127:231-237.
    • (2011) J. Steroid Biochem. Mol. Biol. , vol.127 , pp. 231-237
    • Rao, J.1    Jiang, X.2    Wang, Y.3    Chen, B.4
  • 51
    • 0021994146 scopus 로고
    • Age, glucose intolerance, and non-insulin-dependent diabetes mellitus
    • Reaven G.M., Reaven E.P. Age, glucose intolerance, and non-insulin-dependent diabetes mellitus. J. Am. Geriatr. Soc. 1985, 33:286-290.
    • (1985) J. Am. Geriatr. Soc. , vol.33 , pp. 286-290
    • Reaven, G.M.1    Reaven, E.P.2
  • 52
    • 0034791028 scopus 로고    scopus 로고
    • Soy isoflavones-benefits and risks from nature's selective estrogen receptor modulators (SERMs)
    • (discussion 381S-383S)
    • Setchell K.D. Soy isoflavones-benefits and risks from nature's selective estrogen receptor modulators (SERMs). J. Am. Coll. Nutr. 2001, 20:354S-362S. (discussion 381S-383S).
    • (2001) J. Am. Coll. Nutr. , vol.20
    • Setchell, K.D.1
  • 53
    • 84878249768 scopus 로고    scopus 로고
    • The potential role of ozone in ameliorating the age-related biochemical changes in male rat cerebral cortex
    • Shehata N.I., Abd-Elgawad H.M., Mawsouf M.N., Shaheen A.A. The potential role of ozone in ameliorating the age-related biochemical changes in male rat cerebral cortex. Biogerontology 2012, 13:565-581.
    • (2012) Biogerontology , vol.13 , pp. 565-581
    • Shehata, N.I.1    Abd-Elgawad, H.M.2    Mawsouf, M.N.3    Shaheen, A.A.4
  • 54
    • 0037397635 scopus 로고    scopus 로고
    • Estrogen and cognitive functioning in women
    • Sherwin B.B. Estrogen and cognitive functioning in women. Endocr. Rev. 2003, 24:133-151.
    • (2003) Endocr. Rev. , vol.24 , pp. 133-151
    • Sherwin, B.B.1
  • 55
    • 0034897070 scopus 로고    scopus 로고
    • Insulin resistance as a major determinant of increased coronary heart disease risk in postmenopausal women with type 2 diabetes mellitus
    • Stoney R.M., O'Dea K., Herbert K.E., Dragicevic G., Giles G.G., Cumpston G.N., Best J.D. Insulin resistance as a major determinant of increased coronary heart disease risk in postmenopausal women with type 2 diabetes mellitus. Diabet. Med. 2001, 18:476-482.
    • (2001) Diabet. Med. , vol.18 , pp. 476-482
    • Stoney, R.M.1    O'Dea, K.2    Herbert, K.E.3    Dragicevic, G.4    Giles, G.G.5    Cumpston, G.N.6    Best, J.D.7
  • 56
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. PNAS 1979, 76:4350-4354.
    • (1979) PNAS , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 57
    • 0030880014 scopus 로고    scopus 로고
    • Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells
    • Wang C., Kurzer M.S. Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells. Nutr. Cancer 1997, 28:236-247.
    • (1997) Nutr. Cancer , vol.28 , pp. 236-247
    • Wang, C.1    Kurzer, M.S.2
  • 58
    • 0037204526 scopus 로고    scopus 로고
    • Age differentially influences estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) gene expression in specific regions of the rat brain
    • Wilson M.E., Rosewell K.L., Kashon M.L., Shughrue P.J., Merchenthaler I., Wise P.M. Age differentially influences estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) gene expression in specific regions of the rat brain. Mech. Ageing Dev. 2002, 123:593-601.
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 593-601
    • Wilson, M.E.1    Rosewell, K.L.2    Kashon, M.L.3    Shughrue, P.J.4    Merchenthaler, I.5    Wise, P.M.6
  • 59
    • 0024561501 scopus 로고
    • Cytochrome oxidase: an endogenous metabolic marker for neuronal activity
    • Wong-Riley M.T. Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. Trends Neurosci. 1989, 12:94-101.
    • (1989) Trends Neurosci. , vol.12 , pp. 94-101
    • Wong-Riley, M.T.1
  • 60
    • 1642464725 scopus 로고    scopus 로고
    • Genistein ameliorates beta-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis
    • Zeng H., Chen Q., Zhao B. Genistein ameliorates beta-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis. Free Radic. Biol. Med. 2004, 36:180-188.
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 180-188
    • Zeng, H.1    Chen, Q.2    Zhao, B.3
  • 61
    • 0036655701 scopus 로고    scopus 로고
    • Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons
    • Zhao L., Chen Q., Diaz Brinton R. Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons. Exp. Biol. Med. (Maywood) 2002, 227:509-519.
    • (2002) Exp. Biol. Med. (Maywood) , vol.227 , pp. 509-519
    • Zhao, L.1    Chen, Q.2    Diaz Brinton, R.3
  • 62
    • 80052640194 scopus 로고    scopus 로고
    • 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention
    • Zhao L., Yao J., Mao Z., Chen S., Wang Y., Brinton R.D. 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention. Neurobiol. Aging 2011, 32:1949-1963.
    • (2011) Neurobiol. Aging , vol.32 , pp. 1949-1963
    • Zhao, L.1    Yao, J.2    Mao, Z.3    Chen, S.4    Wang, Y.5    Brinton, R.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.