-
1
-
-
0036734848
-
Characterization of chemokines and their receptors in the central nervous system: Physiopathological implications
-
Bajetto A, Bonavia R, Barbero S, Schettini G (2002) Characterization of chemokines and their receptors in the central nervous system: physiopathological implications. J Neurochem 82:1311-1329.
-
(2002)
J Neurochem
, vol.82
, pp. 1311-1329
-
-
Bajetto, A.1
Bonavia, R.2
Barbero, S.3
Schettini, G.4
-
2
-
-
0033136947
-
The role of p38 mitogen-activated protein kinase in IL-1{beta} transcription
-
Baldassare JJ, Bi Y, Bellone CJ (1999) The role of p38 mitogen-activated protein kinase in IL-1{beta} transcription. J Immunol 162:5367-5373.
-
(1999)
J Immunol
, vol.162
, pp. 5367-5373
-
-
Baldassare, J.J.1
Bi, Y.2
Bellone, C.J.3
-
3
-
-
34250873991
-
Role of the cysteine protease cathepsin S in neuropathic hyperalgesia
-
Barclay J, Clark AK, Ganju P, Gentry C, Patel S, Wotherspoon G, Buxton F, Song C, Ullah J, Winter J, Fox A, Bevan S, Malcangio M (2007) Role of the cysteine protease cathepsin S in neuropathic hyperalgesia. Pain 130:225-234.
-
(2007)
Pain
, vol.130
, pp. 225-234
-
-
Barclay, J.1
Clark, A.K.2
Ganju, P.3
Gentry, C.4
Patel, S.5
Wotherspoon, G.6
Buxton, F.7
Song, C.8
Ullah, J.9
Winter, J.10
Fox, A.11
Bevan, S.12
Malcangio, M.13
-
4
-
-
0031036347
-
A new class of membrane-bound chemokine with a CX3C motif
-
Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A, Schall TJ (1997) A new class of membrane-bound chemokine with a CX3C motif. Nature 385:640-644.
-
(1997)
Nature
, vol.385
, pp. 640-644
-
-
Bazan, J.F.1
Bacon, K.B.2
Hardiman, G.3
Wang, W.4
Soo, K.5
Rossi, D.6
Greaves, D.R.7
Zlotnik, A.8
Schall, T.J.9
-
5
-
-
12444288446
-
Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo
-
Beers C, Burich A, Kleijmeer MJ, Griffith JM, Wong P, Rudensky AY (2005) Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo. J Immunol 174:1205-1212.
-
(2005)
J Immunol
, vol.174
, pp. 1205-1212
-
-
Beers, C.1
Burich, A.2
Kleijmeer, M.J.3
Griffith, J.M.4
Wong, P.5
Rudensky, A.Y.6
-
6
-
-
33947716251
-
Identification of a novel class of succinyl-nitrile-based cathepsin S inhibitors
-
Bekkali Y, Thomson DS, Betageri R, Emmanuel MJ, Hao MH, Hickey E, Liu W, Patel U, Ward YD, Young ERR, Nelson R, Kukulka A, Brown ML, Crane K, White D, Freeman DM, Labadia ME, Wildeson J, Spero DM (2007) Identification of a novel class of succinyl-nitrile-based cathepsin S inhibitors. Bioorgan Med Chem Lett 17:2465-2469.
-
(2007)
Bioorgan Med Chem Lett
, vol.17
, pp. 2465-2469
-
-
Bekkali, Y.1
Thomson, D.S.2
Betageri, R.3
Emmanuel, M.J.4
Hao, M.H.5
Hickey, E.6
Liu, W.7
Patel, U.8
Ward, Y.D.9
Young, E.R.R.10
Nelson, R.11
Kukulka, A.12
Brown, M.L.13
Crane, K.14
White, D.15
Freeman, D.M.16
Labadia, M.E.17
Wildeson, J.18
Spero, D.M.19
-
7
-
-
0011720253
-
Role for intracellular proteases in the processing and transport of class II HLA antigens
-
Blum JS, Cresswell P (1988) Role for intracellular proteases in the processing and transport of class II HLA antigens. PNAS 85:3975-3979.
-
(1988)
PNAS
, vol.85
, pp. 3975-3979
-
-
Blum, J.S.1
Cresswell, P.2
-
8
-
-
0021343788
-
Human cystatin, a new protein inhibitor of cysteine proteinases
-
Brzin J, Popovic T, Turk V, Borchart U, Machleidt W (1984) Human cystatin, a new protein inhibitor of cysteine proteinases. Biochem Biophys Res Commun 118:103-109.
-
(1984)
Biochem Biophys Res Commun
, vol.118
, pp. 103-109
-
-
Brzin, J.1
Popovic, T.2
Turk, V.3
Borchart, U.4
Machleidt, W.5
-
9
-
-
0034654533
-
Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1{beta} in RAW264 macrophages
-
Caivano M, Cohen P (2000) Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1{beta} in RAW264 macrophages. J Immunol 164:3018-3025.
-
(2000)
J Immunol
, vol.164
, pp. 3018-3025
-
-
Caivano, M.1
Cohen, P.2
-
10
-
-
0345381021
-
Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage
-
Chapman GA, Moores K, Harrison D, Campbell CA, Stewart BR, Strijbos P J LM (2000) Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage. J Neurosci 20:87RC.
-
(2000)
J Neurosci
, vol.20
, pp. 87RC
-
-
Chapman, G.A.1
Moores, K.2
Harrison, D.3
Campbell, C.A.4
Stewart, B.R.5
Strijbos, P.J.L.M.6
-
11
-
-
34247334237
-
Synthesis and SAR of succinamide peptidomimetic inhibitors of cathepsin S
-
Chatterjee AK, Liu H, Tully DC, Guo J, Epple R, Russo R, Williams J, Roberts M, Tuntland T, Chang J, Gordon P, Hollenbeck T, Tumanut C, Li J, Harris JL (2007) Synthesis and SAR of succinamide peptidomimetic inhibitors of cathepsin S. Bioorgan Med Chem Lett 17:2899-2903.
-
(2007)
Bioorgan Med Chem Lett
, vol.17
, pp. 2899-2903
-
-
Chatterjee, A.K.1
Liu, H.2
Tully, D.C.3
Guo, J.4
Epple, R.5
Russo, R.6
Williams, J.7
Roberts, M.8
Tuntland, T.9
Chang, J.10
Gordon, P.11
Hollenbeck, T.12
Tumanut, C.13
Li, J.14
Harris, J.L.15
-
12
-
-
33750056359
-
Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation
-
Clark AK, D'Aquisto F, Gentry C, Marchand F, McMahon SB, Malcangio M (2006) Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation. J Neurochem 99:868-880.
-
(2006)
J Neurochem
, vol.99
, pp. 868-880
-
-
Clark, A.K.1
D'Aquisto, F.2
Gentry, C.3
Marchand, F.4
McMahon, S.B.5
Malcangio, M.6
-
13
-
-
34547505414
-
Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain
-
Clark AK, Yip PK, Grist J, Gentry C, Staniland AA, Marchand F, Dehvari M, Wotherspoon G, Winter J, Ullah J, Bevan S, Malcangio M (2007a) Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain. PNAS 104:10655-10660.
-
(2007)
PNAS
, vol.104
, pp. 10655-10660
-
-
Clark, A.K.1
Yip, P.K.2
Grist, J.3
Gentry, C.4
Staniland, A.A.5
Marchand, F.6
Dehvari, M.7
Wotherspoon, G.8
Winter, J.9
Ullah, J.10
Bevan, S.11
Malcangio, M.12
-
14
-
-
33751513963
-
Role of spinal microglia in rat models of peripheral nerve injury and inflammation
-
Clark AK, Gentry C, Bradbury EJ, McMahon SB, Malcangio M (2007b) Role of spinal microglia in rat models of peripheral nerve injury and inflammation. Eur J Pain 11:223-230.
-
(2007)
Eur J Pain
, vol.11
, pp. 223-230
-
-
Clark, A.K.1
Gentry, C.2
Bradbury, E.J.3
McMahon, S.B.4
Malcangio, M.5
-
15
-
-
0037175326
-
Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury
-
Costigan M, Befort K, Karchewski L, Griffin RS, D'Urso D, Allchorne A, Sitarski J, Mannion JW, Pratt RE, Woolf CJ (2002) Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci 3:16.
-
(2002)
BMC Neurosci
, vol.3
, pp. 16
-
-
Costigan, M.1
Befort, K.2
Karchewski, L.3
Griffin, R.S.4
D'Urso, D.5
Allchorne, A.6
Sitarski, J.7
Mannion, J.W.8
Pratt, R.E.9
Woolf, C.J.10
-
16
-
-
30744439794
-
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
-
Coull JA, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y (2005) BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature 438:1017-1021.
-
(2005)
Nature
, vol.438
, pp. 1017-1021
-
-
Coull, J.A.1
Beggs, S.2
Boudreau, D.3
Boivin, D.4
Tsuda, M.5
Inoue, K.6
Gravel, C.7
Salter, M.W.8
De Koninck, Y.9
-
17
-
-
0032079675
-
Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior
-
Coyle DE (1998) Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior. Glia 23:75-83.
-
(1998)
Glia
, vol.23
, pp. 75-83
-
-
Coyle, D.E.1
-
18
-
-
0028981178
-
HLA-DM induces clip dissociation from MHC class II [alpha][beta] dimers and facilitates peptide loading
-
Denzin LK, Cresswell P (1995) HLA-DM induces clip dissociation from MHC class II [alpha][beta] dimers and facilitates peptide loading. Cell 82:155-165.
-
(1995)
Cell
, vol.82
, pp. 155-165
-
-
Denzin, L.K.1
Cresswell, P.2
-
19
-
-
0033571691
-
Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells
-
Driessen C, Bryant RAR, Lennon-Dumenil AM, Villadangos JA, Bryant PW, Shi GP, Chapman HA, Ploegh HL (1999) Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells. J Cell Biol 147:775-790.
-
(1999)
J Cell Biol
, vol.147
, pp. 775-790
-
-
Driessen, C.1
Bryant, R.A.R.2
Lennon-Dumenil, A.M.3
Villadangos, J.A.4
Bryant, P.W.5
Shi, G.P.6
Chapman, H.A.7
Ploegh, H.L.8
-
20
-
-
0035851124
-
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)
-
Garton KJ, Gough PJ, Blobel CP, Murphy G, Greaves DR, Dempsey PJ, Raines EW (2001) Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1). J Biol Chem 276:37993-38001.
-
(2001)
J Biol Chem
, vol.276
, pp. 37993-38001
-
-
Garton, K.J.1
Gough, P.J.2
Blobel, C.P.3
Murphy, G.4
Greaves, D.R.5
Dempsey, P.J.6
Raines, E.W.7
-
21
-
-
34547539149
-
The identification of potent, selective, and bioavailable cathepsin S inhibitors
-
Gauthier JY, Black WC, Courchesne I, Cromlish W, Desmarais S, Houle R, Lamontagne S, Li CS, Massq F, McKay DJ, Ouellet M, Robichaud J, Truchon JF, Truong VL, Wang Q, Percival MD (2007) The identification of potent, selective, and bioavailable cathepsin S inhibitors. Bioorgan Med Chem Lett 17:4929-4933.
-
(2007)
Bioorgan Med Chem Lett
, vol.17
, pp. 4929-4933
-
-
Gauthier, J.Y.1
Black, W.C.2
Courchesne, I.3
Cromlish, W.4
Desmarais, S.5
Houle, R.6
Lamontagne, S.7
Li, C.S.8
Massq, F.9
McKay, D.J.10
Ouellet, M.11
Robichaud, J.12
Truchon, J.F.13
Truong, V.L.14
Wang, Q.15
Percival, M.D.16
-
22
-
-
0028823585
-
The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3
-
Ghosh P, Amaya M, Mellins E, Wiley DC (1995) The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature 378:457-462.
-
(1995)
Nature
, vol.378
, pp. 457-462
-
-
Ghosh, P.1
Amaya, M.2
Mellins, E.3
Wiley, D.C.4
-
23
-
-
13144279282
-
Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
-
Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK, Streit WJ, Salafranca MN, Adhikari S, Thompson DA, Botti P, Bacon KB, Feng L (1998) Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. PNAS 95:10896-10901.
-
(1998)
PNAS
, vol.95
, pp. 10896-10901
-
-
Harrison, J.K.1
Jiang, Y.2
Chen, S.3
Xia, Y.4
Maciejewski, D.5
McNamara, R.K.6
Streit, W.J.7
Salafranca, M.N.8
Adhikari, S.9
Thompson, D.A.10
Botti, P.11
Bacon, K.B.12
Feng, L.13
-
24
-
-
0037085719
-
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS
-
Hughes PM, Botham MS, Frentzel S, Mir A, Perry VH (2002) Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia 37:314-327.
-
(2002)
Glia
, vol.37
, pp. 314-327
-
-
Hughes, P.M.1
Botham, M.S.2
Frentzel, S.3
Mir, A.4
Perry, V.H.5
-
25
-
-
0042237924
-
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
-
Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A (2003) The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 102:1186-1195.
-
(2003)
Blood
, vol.102
, pp. 1186-1195
-
-
Hundhausen, C.1
Misztela, D.2
Berkhout, T.A.3
Broadway, N.4
Saftig, P.5
Reiss, K.6
Hartmann, D.7
Fahrenholz, F.8
Postina, R.9
Matthews, V.10
Kallen, K.J.11
Rose-John, S.12
Ludwig, A.13
-
26
-
-
0030723388
-
Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion
-
Imai T, Hieshima K, Haskell C, Baba M, Nagira M, Nishimura M, Kakizaki M, Takagi S, Nomiyama H, Schall TJ, Yoshie O (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91:521-530.
-
(1997)
Cell
, vol.91
, pp. 521-530
-
-
Imai, T.1
Hieshima, K.2
Haskell, C.3
Baba, M.4
Nagira, M.5
Nishimura, M.6
Kakizaki, M.7
Takagi, S.8
Nomiyama, H.9
Schall, T.J.10
Yoshie, O.11
-
27
-
-
34250219213
-
Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode
-
Inagaki H, Tsuruoka H, Hornsby M, Lesley SA, Spraggon G, Ellman JA (2007) Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode. J Med Chem 50:2693-2699.
-
(2007)
J Med Chem
, vol.50
, pp. 2693-2699
-
-
Inagaki, H.1
Tsuruoka, H.2
Hornsby, M.3
Lesley, S.A.4
Spraggon, G.5
Ellman, J.A.6
-
28
-
-
52449132931
-
Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain
-
Irie O, Kosaka T, Ehara T, Yokokawa F, Kanazawa T, Hirao H, Iwasaki A, Sakaki J, Teno N, Hitomi Y, Iwasaki G, Fukaya H, Nonomura K, Tanabe K, Koizumi S, Uchiyama N, Bevan SJ, Malcangio M, Gentry C, Fox AJ, Yaqoob M, Culshaw A J, Hallett A (2008a) Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain. J Med Chem.
-
(2008)
J Med Chem.
-
-
Irie, O.1
Kosaka, T.2
Ehara, T.3
Yokokawa, F.4
Kanazawa, T.5
Hirao, H.6
Iwasaki, A.7
Sakaki, J.8
Teno, N.9
Hitomi, Y.10
Iwasaki, G.11
Fukaya, H.12
Nonomura, K.13
Tanabe, K.14
Koizumi, S.15
Uchiyama, N.16
Bevan, S.J.17
Malcangio, M.18
Gentry, C.19
Fox, A.J.20
Yaqoob, M.21
Culshaw, A.J.22
Hallett, A.23
more..
-
29
-
-
47149115085
-
Discovery of selective and nonpeptidic cathepsin S inhibitors
-
Irie O, Ehara T, Iwasaki A, Yokokawa F, Sakaki J, Hirao H, Kanazawa T, Teno N, Horiuchi M, Umemura I, Gunji H, Masuya K, Hitomi Y, Iwasaki G, Nonomura K, Tanabe K, Fukaya H, Kosaka T, Snell CR, Hallett A (2008b) Discovery of selective and nonpeptidic cathepsin S inhibitors. Bioorgan Med Chem Lett 51:5502-5505.
-
(2008)
Bioorgan Med Chem Lett
, vol.51
, pp. 5502-5505
-
-
Irie, O.1
Ehara, T.2
Iwasaki, A.3
Yokokawa, F.4
Sakaki, J.5
Hirao, H.6
Kanazawa, T.7
Teno, N.8
Horiuchi, M.9
Umemura, I.10
Gunji, H.11
Masuya, K.12
Hitomi, Y.13
Iwasaki, G.14
Nonomura, K.15
Tanabe, K.16
Fukaya, H.17
Kosaka, T.18
Snell, C.R.19
Hallett, A.20
more..
-
30
-
-
0037705314
-
P38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
-
Jin SX, Zhuang ZY, Woolf CJ, Ji RR (2003) p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci 23:4017-4022.
-
(2003)
J Neurosci
, vol.23
, pp. 4017-4022
-
-
Jin, S.X.1
Zhuang, Z.Y.2
Woolf, C.J.3
Ji, R.R.4
-
31
-
-
1542298238
-
Importance of MAPK pathways for microglial proinflammatory cytokine IL-1[beta] production
-
Kim SH, Smith CJ, Van Eldik LJ (2004) Importance of MAPK pathways for microglial proinflammatory cytokine IL-1[beta] production. Neurobiol Aging 25:431-439.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 431-439
-
-
Kim, S.H.1
Smith, C.J.2
Van Eldik, L.J.3
-
32
-
-
0036723908
-
Analysis of genes induced in peripheral nerve after axotomy using cDNA microarrays
-
Kubo T, Yamashita T, Yamaguchi A, Hosokawa K, Tohyama M (2002) Analysis of genes induced in peripheral nerve after axotomy using cDNA microarrays. J Neurochem 82:1129-1136.
-
(2002)
J Neurochem
, vol.82
, pp. 1129-1136
-
-
Kubo, T.1
Yamashita, T.2
Yamaguchi, A.3
Hosokawa, K.4
Tohyama, M.5
-
33
-
-
21544469729
-
Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain
-
Lindia JA, McGowan E, Jochnowitz N, Abbadie C (2005) Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. J Pain 6:434-438.
-
(2005)
J Pain
, vol.6
, pp. 434-438
-
-
Lindia, J.A.1
McGowan, E.2
Jochnowitz, N.3
Abbadie, C.4
-
34
-
-
21244490018
-
Recycling of the membrane-anchored chemokine, CX3CL1
-
Liu GY, Kulasingam V, Alexander RT, Touret N, Fong AM, Patel DD, Robinson LA (2005) Recycling of the membrane-anchored chemokine, CX3CL1. J Biol Chem 280:19858-19866.
-
(2005)
J Biol Chem
, vol.280
, pp. 19858-19866
-
-
Liu, G.Y.1
Kulasingam, V.2
Alexander, R.T.3
Touret, N.4
Fong, A.M.5
Patel, D.D.6
Robinson, L.A.7
-
35
-
-
0032783985
-
Neurotrophic factors regulate cathepsin S in macrophages and microglia: A role in the degradation of myelin basic protein and amyloid beta peptide
-
Liuzzo JP, Petanceska SS, Devi LA (1999a) Neurotrophic factors regulate cathepsin S in macrophages and microglia: a role in the degradation of myelin basic protein and amyloid beta peptide. Mol Med 5:334-343.
-
(1999)
Mol Med
, vol.5
, pp. 334-343
-
-
Liuzzo, J.P.1
Petanceska, S.S.2
Devi, L.A.3
-
36
-
-
0032776292
-
Inflammatory mediators regulate cathepsin S in macrophages and microglia: A role in attenuating heparan sulfate interactions
-
Liuzzo JP, Petanceska SS, Moscatelli D, Devi LA (1999b) Inflammatory mediators regulate cathepsin S in macrophages and microglia: a role in attenuating heparan sulfate interactions. Mol Med 5:320-333.
-
(1999)
Mol Med
, vol.5
, pp. 320-333
-
-
Liuzzo, J.P.1
Petanceska, S.S.2
Moscatelli, D.3
Devi, L.A.4
-
37
-
-
8144221210
-
Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats
-
Milligan ED, Zapata V, Chacur M, Schoeniger D, Biedenkapp J, O'Connor KA, Verge GM, Chapman G, Green P, Foster AC, Naeve GS, Maier SF, Watkins LR (2004) Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats. Eur J Neurosci 20:2294-2302.
-
(2004)
Eur J Neurosci
, vol.20
, pp. 2294-2302
-
-
Milligan, E.D.1
Zapata, V.2
Chacur, M.3
Schoeniger, D.4
Biedenkapp, J.5
O'Connor, K.A.6
Verge, G.M.7
Chapman, G.8
Green, P.9
Foster, A.C.10
Naeve, G.S.11
Maier, S.F.12
Watkins, L.R.13
-
38
-
-
29144442969
-
An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine
-
Milligan E, Zapata V, Schoeniger D, Chacur M, Green P, Poole S, Martin D, Maier SF, Watkins LR (2005) An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine. Eur J Neurosci 22:2775-2782.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2775-2782
-
-
Milligan, E.1
Zapata, V.2
Schoeniger, D.3
Chacur, M.4
Green, P.5
Poole, S.6
Martin, D.7
Maier, S.F.8
Watkins, L.R.9
-
39
-
-
0034092634
-
International union of pharmacology. XXII. Nomenclature for chemokine receptors
-
Murphy PM, Baggiolini M, Charo IF, Hebert CA, Horuk R, Matsushima K, Miller LH, Oppenheim JJ, Power CA (2000) International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 52:145-176.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 145-176
-
-
Murphy, P.M.1
Baggiolini, M.2
Charo, I.F.3
Hebert, C.A.4
Horuk, R.5
Matsushima, K.6
Miller, L.H.7
Oppenheim, J.J.8
Power, C.A.9
-
40
-
-
2442549710
-
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice
-
Nakagawa TY, Brissette WH, Lira PD, Griffiths RJ, Petrushova N, Stock J, McNeish JD, Eastman SE, Howard ED, Clarke SRM (1999) Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity 10:207-217.
-
(1999)
Immunity
, vol.10
, pp. 207-217
-
-
Nakagawa, T.Y.1
Brissette, W.H.2
Lira, P.D.3
Griffiths, R.J.4
Petrushova, N.5
Stock, J.6
McNeish, J.D.7
Eastman, S.E.8
Howard, E.D.9
Clarke, S.R.M.10
-
41
-
-
0032510831
-
Localization of fractalkine and CX3CR1 mRNAs in rat brain: Does fractalkine play a role in signaling from neuron to microglia?
-
Nishiyori A, Minami M, Ohtani Y, Takami S, Yamamoto J, Kawaguchi N, Kume T, Akaike A, Satoh M (1998) Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? FEBS Lett 429:167-172.
-
(1998)
FEBS Lett
, vol.429
, pp. 167-172
-
-
Nishiyori, A.1
Minami, M.2
Ohtani, Y.3
Takami, S.4
Yamamoto, J.5
Kawaguchi, N.6
Kume, T.7
Akaike, A.8
Satoh, M.9
-
42
-
-
33746354314
-
Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn
-
Owolabi SA, Saab CY (2006) Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn. FEBS Lett 580:4306-4310.
-
(2006)
FEBS Lett
, vol.580
, pp. 4306-4310
-
-
Owolabi, S.A.1
Saab, C.Y.2
-
43
-
-
0030949298
-
Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation
-
Pan Y, Lloyd C, Zhou H, Dolich S, Deeds J, Gonzalo JA, Vath J, Gosselin M, Ma J, Dussault B, Woolf E, Alperin G, Culpepper J, Gutierrez-Ramos JC, Gearing D (1997) Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature 387:611-617.
-
(1997)
Nature
, vol.387
, pp. 611-617
-
-
Pan, Y.1
Lloyd, C.2
Zhou, H.3
Dolich, S.4
Deeds, J.5
Gonzalo, J.A.6
Vath, J.7
Gosselin, M.8
Ma, J.9
Dussault, B.10
Woolf, E.11
Alperin, G.12
Culpepper, J.13
Gutierrez-Ramos, J.C.14
Gearing, D.15
-
44
-
-
0027092035
-
Sequence analysis, tissue distribution, and expression of rat cathepsin S
-
Petanceska S, Devi L (1992) Sequence analysis, tissue distribution, and expression of rat cathepsin S. J Biol Chem 267:26038-26043.
-
(1992)
J Biol Chem
, vol.267
, pp. 26038-26043
-
-
Petanceska, S.1
Devi, L.2
-
45
-
-
0028206592
-
Differential distribution of messenger RNAs for cathepsins B, L and S in adult rat brain: An in situ hybridization study
-
Petanceska S, Burke S, Watson SJ, Devi L (1994) Differential distribution of messenger RNAs for cathepsins B, L and S in adult rat brain: an in situ hybridization study. Neuroscience 59:729-738.
-
(1994)
Neuroscience
, vol.59
, pp. 729-738
-
-
Petanceska, S.1
Burke, S.2
Watson, S.J.3
Devi, L.4
-
46
-
-
0030060976
-
Expression of rat cathepsin S in phagocytic cells
-
Petanceska S, Canoll P, Devi LA (1996) Expression of rat cathepsin S in phagocytic cells. J Biol Chem 271:4403-4409.
-
(1996)
J Biol Chem
, vol.271
, pp. 4403-4409
-
-
Petanceska, S.1
Canoll, P.2
Devi, L.A.3
-
47
-
-
0032568806
-
Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells
-
Pierre P, Mellman I (1998) Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells. Cell 93:1135-1145.
-
(1998)
Cell
, vol.93
, pp. 1135-1145
-
-
Pierre, P.1
Mellman, I.2
-
48
-
-
0032103322
-
Cathepsin S activity regulates antigen presentation and immunity
-
Riese RJ, Mitchell RN, Villadangos JA, Shi GP, Palmer JT, Karp ER, De Sanctis GT, Ploegh HL, Chapman HA (1998) Cathepsin S activity regulates antigen presentation and immunity. J Clin Invest 101:2351-2363.
-
(1998)
J Clin Invest
, vol.101
, pp. 2351-2363
-
-
Riese, R.J.1
Mitchell, R.N.2
Villadangos, J.A.3
Shi, G.P.4
Palmer, J.T.5
Karp, E.R.6
De Sanctis, G.T.7
Ploegh, H.L.8
Chapman, H.A.9
-
49
-
-
0029931108
-
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading
-
Riese RJ, Wolf PR, Bromme D, Natkin LR, Villadangos JA, Ploegh HL, Chapman HA (1996) Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading. Immunity 4:357-366.
-
(1996)
Immunity
, vol.4
, pp. 357-366
-
-
Riese, R.J.1
Wolf, P.R.2
Bromme, D.3
Natkin, L.R.4
Villadangos, J.A.5
Ploegh, H.L.6
Chapman, H.A.7
-
50
-
-
0025331726
-
Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
-
Roche PA, Cresswell P (1990) Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature 345:615-618.
-
(1990)
Nature
, vol.345
, pp. 615-618
-
-
Roche, P.A.1
Cresswell, P.2
-
51
-
-
0026353496
-
Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules
-
Roche PA, Cresswell P (1991) Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. PNAS 88:3150-3154.
-
(1991)
PNAS
, vol.88
, pp. 3150-3154
-
-
Roche, P.A.1
Cresswell, P.2
-
52
-
-
35548937457
-
The neuropathic pain triad: Neurons, immune cells and glia
-
Scholz J, Woolf CJ (2007) The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci 10:1361-1368.
-
(2007)
Nat Neurosci
, vol.10
, pp. 1361-1368
-
-
Scholz, J.1
Woolf, C.J.2
-
53
-
-
0031730067
-
Neuronal expression of fractalkine in the presence and absence of inflammation
-
Schwaeble WJ, Stover CM, Schall TJ, Dairaghi DJ, Trinder PKE, Linington C, Iglesias A, Schubart A, Lynch NJ, Weihe E, Schafer MK (1998) Neuronal expression of fractalkine in the presence and absence of inflammation. FEBS Lett 439:203-207.
-
(1998)
FEBS Lett
, vol.439
, pp. 203-207
-
-
Schwaeble, W.J.1
Stover, C.M.2
Schall, T.J.3
Dairaghi, D.J.4
Trinder, P.K.E.5
Linington, C.6
Iglesias, A.7
Schubart, A.8
Lynch, N.J.9
Weihe, E.10
Schafer, M.K.11
-
54
-
-
0029084023
-
DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
-
Sherman MA, Weber DA, Jensen PE (1995) DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity 3:197-205.
-
(1995)
Immunity
, vol.3
, pp. 197-205
-
-
Sherman, M.A.1
Weber, D.A.2
Jensen, P.E.3
-
55
-
-
0026630108
-
Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease
-
Shi GP, Munger JS, Meara JP, Rich DH, Chapman HA (1992) Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease. J Biol Chem 267:7258-7262.
-
(1992)
J Biol Chem
, vol.267
, pp. 7258-7262
-
-
Shi, G.P.1
Munger, J.S.2
Meara, J.P.3
Rich, D.H.4
Chapman, H.A.5
-
56
-
-
0033083688
-
Cathepsin S required for normal MHC class II peptide loading and germinal center development
-
Shi GP, Villadangos JA, Dranoff G, Small C, Gu L, Haley KJ, Riese R, Ploegh HL, Chapman HA (1999) Cathepsin S required for normal MHC class II peptide loading and germinal center development. Immunity 10:197-206.
-
(1999)
Immunity
, vol.10
, pp. 197-206
-
-
Shi, G.P.1
Villadangos, J.A.2
Dranoff, G.3
Small, C.4
Gu, L.5
Haley, K.J.6
Riese, R.7
Ploegh, H.L.8
Chapman, H.A.9
-
57
-
-
0029072047
-
Mediation by HLA-DM of dissociation of peptides from HLA-DR
-
Sloan VS, Cameron P, Porter G, Gammon M, Amaya M, Mellins E, Zaller DM (1995) Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375:802-806.
-
(1995)
Nature
, vol.375
, pp. 802-806
-
-
Sloan, V.S.1
Cameron, P.2
Porter, G.3
Gammon, M.4
Amaya, M.5
Mellins, E.6
Zaller, D.M.7
-
58
-
-
34548137358
-
Pathophysiology of peripheral neuropathic pain: Immune cells and molecules
-
Thacker MA, Clark AK, Marchand F, McMahon SB (2007) Pathophysiology of peripheral neuropathic pain: immune cells and molecules. Anesth Analg 105:838-847.
-
(2007)
Anesth Analg
, vol.105
, pp. 838-847
-
-
Thacker, M.A.1
Clark, A.K.2
Marchand, F.3
McMahon, S.B.4
-
59
-
-
0035976986
-
Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine
-
Tsou CL, Haskell CA, Charo IF (2001) Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine. J Biol Chem 276:44622-44626.
-
(2001)
J Biol Chem
, vol.276
, pp. 44622-44626
-
-
Tsou, C.L.1
Haskell, C.A.2
Charo, I.F.3
-
60
-
-
0042968804
-
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
-
Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, Inoue K (2003) P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature 424:778-783.
-
(2003)
Nature
, vol.424
, pp. 778-783
-
-
Tsuda, M.1
Shigemoto-Mogami, Y.2
Koizumi, S.3
Mizokoshi, A.4
Kohsaka, S.5
Salter, M.W.6
Inoue, K.7
-
61
-
-
0346655315
-
Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury
-
Tsuda M, Mizokoshi A, Shigemoto-Mogami Y, Koizumi S, Inoue K (2004) Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury. Glia 45:89-95.
-
(2004)
Glia
, vol.45
, pp. 89-95
-
-
Tsuda, M.1
Mizokoshi, A.2
Shigemoto-Mogami, Y.3
Koizumi, S.4
Inoue, K.5
-
63
-
-
0142241383
-
Coupling gene chip analyses and rat genetic variances in identifying potential target genes that may contribute to neuropathic allodynia development
-
Valder CR, Liu JJ, Song YH, Luo ZD (2003) Coupling gene chip analyses and rat genetic variances in identifying potential target genes that may contribute to neuropathic allodynia development. J Neurochem 87:560-573.
-
(2003)
J Neurochem
, vol.87
, pp. 560-573
-
-
Valder, C.R.1
Liu, J.J.2
Song, Y.H.3
Luo, Z.D.4
-
64
-
-
13844276525
-
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans
-
Vasiljeva O, Dolinar M, Pungercar JR, Turk V, Turk B (2005) Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett 579:1285-1290.
-
(2005)
FEBS Lett
, vol.579
, pp. 1285-1290
-
-
Vasiljeva, O.1
Dolinar, M.2
Pungercar, J.R.3
Turk, V.4
Turk, B.5
-
65
-
-
4544252839
-
Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions
-
Verge GM, Milligan ED, Maier SF, Watkins LR, Naeve GS, Foster AC (2004) Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Eur J Neurosci 20:1150-1160.
-
(2004)
Eur J Neurosci
, vol.20
, pp. 1150-1160
-
-
Verge, G.M.1
Milligan, E.D.2
Maier, S.F.3
Watkins, L.R.4
Naeve, G.S.5
Foster, A.C.6
-
66
-
-
0030790341
-
Degradation of mouse invariant chain: Roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism
-
Villadangos JA, Riese RJ, Peters C, Chapman HA, Ploegh HL (1997) Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism. J Exp Med 186:549-560.
-
(1997)
J Exp Med
, vol.186
, pp. 549-560
-
-
Villadangos, J.A.1
Riese, R.J.2
Peters, C.3
Chapman, H.A.4
Ploegh, H.L.5
-
67
-
-
0037028023
-
Design and synthesis of dipeptide nitriles as reversible and potent cathepsin S inhibitors
-
Ward YD, Thomson DS, Frye LL, Cywin CL, Morwick T, Emmanuel MJ, Zindell R, McNeil D, Bekkali Y, Girardot M, Hrapchak M, DeTuri M, Crane K, White D, Pav S, Wang Y, Hao MH, Grygon CA, Labadia ME, Freeman DM, Davidson W, Hopkins JL, Brown ML, Spero DM (2002) Design and synthesis of dipeptide nitriles as reversible and potent cathepsin S inhibitors. J Med Chem 45:5471-5482.
-
(2002)
J Med Chem
, vol.45
, pp. 5471-5482
-
-
Ward, Y.D.1
Thomson, D.S.2
Frye, L.L.3
Cywin, C.L.4
Morwick, T.5
Emmanuel, M.J.6
Zindell, R.7
McNeil, D.8
Bekkali, Y.9
Girardot, M.10
Hrapchak, M.11
DeTuri, M.12
Crane, K.13
White, D.14
Pav, S.15
Wang, Y.16
Hao, M.H.17
Grygon, C.A.18
Labadia, M.E.19
Freeman, D.M.20
Davidson, W.21
Hopkins, J.L.22
Brown, M.L.23
Spero, D.M.24
more..
-
68
-
-
34548580127
-
Pyrazole-based cathepsin S inhibitors with improved cellular potency
-
Wei J, Pio BA, Cai H, Meduna SP, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP (2007) Pyrazole-based cathepsin S inhibitors with improved cellular potency. Bioorgan Med Chem Lett 17:5525-5528.
-
(2007)
Bioorgan Med Chem Lett
, vol.17
, pp. 5525-5528
-
-
Wei, J.1
Pio, B.A.2
Cai, H.3
Meduna, S.P.4
Sun, S.5
Gu, Y.6
Jiang, W.7
Thurmond, R.L.8
Karlsson, L.9
Edwards, J.P.10
-
69
-
-
34249717859
-
Roleof the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine
-
Zhuang ZY, Kawasaki Y, Tan PH, Wen YR, Huang J, Ji RR (2007) Roleof the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun 21:642-651.
-
(2007)
Brain Behav Immun
, vol.21
, pp. 642-651
-
-
Zhuang, Z.Y.1
Kawasaki, Y.2
Tan, P.H.3
Wen, Y.R.4
Huang, J.5
Ji, R.R.6
|