Single and 90-day repeated oral dose toxicity studies of fermented Rhus verniciflua stem bark extract in Sprague-Dawley rats

Food and Chemical Toxicology

Volumn 55, Issue , 2013, Pages 617-626

  Shin, Seo Ho ^a,c   Koo, Kyo Hwan ^a   Bae, Jin Sook ^a   Cha, Seung Bum ^a   Kang, In Soo ^a   Kang, Min Soo ^a   Kim, Hak Soo ^a   Heo, Hyun Suk ^a   Park, Min Su ^a   Gil, Gi Hyun ^a   Lee, Joo Young ^a   Kim, Kap Ho ^a   Li, Yinghua ^a   Lee, Hyun Kul ^a   Song, Si Whan ^a   Choi, Han Seok ^b   Kang, Boo Hyon ^a   Kim, Jong Choon ^c  

^a Chemon Inc   (South Korea)

^b National Institute of Animal Science   (South Korea)

^c Chonnam National University   (South Korea)

Author keywords

Acute toxicity; Fermented Rhus verniciflua stem bark extract; Phenolic compounds; Subchronic toxicity; Urushiol

Indexed keywords

CHLORINE; CREATININE; PLANT EXTRACT; RHUS VERNICIFLUA EXTRACT; SODIUM; UNCLASSIFIED DRUG;

ADVERSE OUTCOME; ANACARDIACEAE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BARK; BODY WEIGHT; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; EYE EXAMINATION; FEMALE; FERMENTED PRODUCT; FLUID INTAKE; HISTOPATHOLOGY; LOOSE FECES; LYMPHOCYTE COUNT; MALE; NEUTROPHIL COUNT; NONHUMAN; ORGAN WEIGHT; PLANT STEM; RAT; RHUS VERNICIFLUA; SINGLE DRUG DOSE; TOXICITY TESTING; URINALYSIS;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING BEHAVIOR; FEEDING BEHAVIOR; FEMALE; FERMENTATION; MALE; PLANT BARK; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RHUS;

EID: 84874734654     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.01.043     Document Type: Article

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