Inhibition of the PI3K/AKT Pathway Reduces Tumor Necrosis Factor-Alpha Production in the Cellular Response to Wear Particles In Vitro

Artificial Organs

Volumn 37, Issue 3, 2013, Pages 298-307

  Huang, Jian Bin ^a   Ding, Yue ^a   Huang, Dong Sheng ^a   Liang, An Jing ^a   Zeng, Wei Ke ^a   Zeng, Zhan Peng ^a   Qin, Chu Qiang ^a   Barden, Bertram ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Aseptic loosening; Joint replacement; Macrophage; PI3K AKT

Indexed keywords

CHEMICAL ACTIVATION; GLYCOPROTEINS; JOINT PROSTHESES; PHYSIOLOGY; POLYMERASE CHAIN REACTION; TUMORS;

ASEPTIC LOOSENING; CELLULAR RESPONSE; CLINICAL EFFECTS; IN-VITRO; JOINT REPLACEMENT; LY294002; PI3K/AKT; TNF Α; TUMOR NECROSIS FACTOR-ALPHA; WEAR PARTICLES;

MACROPHAGES;

2 MORPHOLINO 8 PHENYLCHROMONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P85; RNA; TITANIUM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CERAMICS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROSTHESIS LOOSENING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84874729089     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2012.01568.x     Document Type: Article

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