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Volumn 109, Issue 2, 2013, Pages 229-237

Platelet protein S directly inhibits procoagulant activity on platelets and microparticles

Author keywords

Activated protein C; Anticoagulant activity; Microparticles; Platelets; Protein S

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; NEUTRALIZING ANTIBODY; PROCOAGULANT; PROTEIN S; PROTEINASE; PROTHROMBIN; THROMBIN;

EID: 84874709181     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH12-08-0622     Document Type: Article
Times cited : (22)

References (32)
  • 1
    • 0025738740 scopus 로고
    • Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles
    • Tans G, Rosing J, Thomassen MC, Heeb MJ, et al. Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles. Blood 1991; 77: 2641-2648.
    • (1991) Blood , vol.77 , pp. 2641-2648
    • Tans, G.1    Rosing, J.2    Thomassen, M.C.3    Heeb, M.J.4
  • 2
    • 0022411427 scopus 로고
    • Identification and quantitation of protein S in human platelets
    • Schwarz HP, Heeb MJ, Wencel-Drake JD, et al. Identification and quantitation of protein S in human platelets. Blood 1985; 66: 1452-1455.
    • (1985) Blood , vol.66 , pp. 1452-1455
    • Schwarz, H.P.1    Heeb, M.J.2    Wencel-Drake, J.D.3
  • 3
    • 0021740029 scopus 로고
    • Plasma protein S deficiency in familial thrombotic disease
    • Schwarz HP, Fischer M, Hopmeier P, et al. Plasma protein S deficiency in familial thrombotic disease. Blood 1984; 64: 1297-1300.
    • (1984) Blood , vol.64 , pp. 1297-1300
    • Schwarz, H.P.1    Fischer, M.2    Hopmeier, P.3
  • 4
    • 70349656483 scopus 로고    scopus 로고
    • Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
    • Burstyn-Cohen T, Heeb MJ, Lemke G. Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis. J Clin Invest 2009; 119: 2942-2953.
    • (2009) J Clin Invest , vol.119 , pp. 2942-2953
    • Burstyn-Cohen, T.1    Heeb, M.J.2    Lemke, G.3
  • 5
    • 70349575804 scopus 로고    scopus 로고
    • Generation and phenotypic analysis of protein S-deficient mice
    • Saller F, Brisset AC, Tchaikovski SN, et al. Generation and phenotypic analysis of protein S-deficient mice. Blood 2009; 114: 2307-2314.
    • (2009) Blood , vol.114 , pp. 2307-2314
    • Saller, F.1    Brisset, A.C.2    Tchaikovski, S.N.3
  • 6
    • 84859316481 scopus 로고    scopus 로고
    • Antithrombotic activity of protein S infused without APC in a baboon thrombosis model
    • Heeb MJ, Marzec U, Gruber A, et al. Antithrombotic activity of protein S infused without APC in a baboon thrombosis model. Thromb Haemost 2012; 107: 690-698.
    • (2012) Thromb Haemost , vol.107 , pp. 690-698
    • Heeb, M.J.1    Marzec, U.2    Gruber, A.3
  • 7
    • 0023731990 scopus 로고
    • Kinetics of inactivation of membrane-bound FVa by APC. Protein S modulates FXa protection
    • Solymoss S, Tucker MM, Tracy PB. Kinetics of inactivation of membrane-bound FVa by APC. Protein S modulates FXa protection. J Biol Chem 1988; 263: 14884-14890.
    • (1988) J Biol Chem , vol.263 , pp. 14884-14890
    • Solymoss, S.1    Tucker, M.M.2    Tracy, P.B.3
  • 8
    • 0022000553 scopus 로고
    • Protein S is required for bovine platelets to support APC binding and activity
    • Harris KW, Esmon CT. Protein S is required for bovine platelets to support APC binding and activity. J Biol Chem 1985; 260: 2007-2010.
    • (1985) J Biol Chem , vol.260 , pp. 2007-2010
    • Harris, K.W.1    Esmon, C.T.2
  • 9
    • 0010336865 scopus 로고
    • Isolation and sequence of the cDNA for protein S, a regulator of blood coagulation
    • Lundwall A, Dackowski W, Cohen E, et al. Isolation and sequence of the cDNA for protein S, a regulator of blood coagulation. Proc Natl Acad Sci USA 1986; 83: 6716-6720.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6716-6720
    • Lundwall, A.1    Dackowski, W.2    Cohen, E.3
  • 10
    • 0023091788 scopus 로고
    • Cleavage of protein S by a platelet membrane protease
    • Mitchell CA, Salem HH. Cleavage of protein S by a platelet membrane protease. J Clin Invest 1987; 79: 374-379.
    • (1987) J Clin Invest , vol.79 , pp. 374-379
    • Mitchell, C.A.1    Salem, H.H.2
  • 11
    • 0032496225 scopus 로고    scopus 로고
    • Human protein S cleavage and inactivation by coagulation FXa
    • Long GL, Lu D, Xie RL, et al. Human protein S cleavage and inactivation by coagulation FXa. J Biol Chem 1998; 273: 11521-11526.
    • (1998) J Biol Chem , vol.273 , pp. 11521-11526
    • Long, G.L.1    Lu, D.2    Xie, R.L.3
  • 12
    • 0038132338 scopus 로고    scopus 로고
    • APC-dependent and-independent anticoagulant activities of protein S have different structural requirements
    • Heeb MJ, Griffin JH. APC-dependent and-independent anticoagulant activities of protein S have different structural requirements. Blood Cells Mol Dis 2002; 29: 190-199.
    • (2002) Blood Cells Mol Dis , vol.29 , pp. 190-199
    • Heeb, M.J.1    Griffin, J.H.2
  • 13
    • 29244477850 scopus 로고    scopus 로고
    • Proteolytic cleavage of protein S during the hemostatic response
    • Brinkman HJ, Mertens K, van Mourik JA. Proteolytic cleavage of protein S during the hemostatic response. J Thromb Haemost 2005; 3: 2712-2720.
    • (2005) J Thromb Haemost , vol.3 , pp. 2712-2720
    • Brinkman, H.J.1    Mertens, K.2    van Mourik, J.A.3
  • 14
    • 0024502137 scopus 로고
    • Activation and complexation of protein C and cleavage and decrease of protein S in plasma of patients with intravascular coagulation
    • Heeb MJ, Mosher D, Griffin JH. Activation and complexation of protein C and cleavage and decrease of protein S in plasma of patients with intravascular coagulation. Blood 1989; 73: 455-461.
    • (1989) Blood , vol.73 , pp. 455-461
    • Heeb, M.J.1    Mosher, D.2    Griffin, J.H.3
  • 15
    • 0028110027 scopus 로고
    • The mechanism of inactivation of FV and FVa by APC
    • Kalafatis M, Rand MD, Mann KG. The mechanism of inactivation of FV and FVa by APC. J Biol Chem 1994; 269: 31869-31880.
    • (1994) J Biol Chem , vol.269 , pp. 31869-31880
    • Kalafatis, M.1    Rand, M.D.2    Mann, K.G.3
  • 16
    • 0034161511 scopus 로고    scopus 로고
    • Regulation of FVIIIa by APC and protein S: Inactivation of cofactor in the intrinsic FXase
    • O'Brien LM, Mastri M, Fay PJ. Regulation of FVIIIa by APC and protein S: Inactivation of cofactor in the intrinsic FXase. Blood 2000; 95: 1714-1720.
    • (2000) Blood , vol.95 , pp. 1714-1720
    • O'Brien, L.M.1    Mastri, M.2    Fay, P.J.3
  • 17
    • 77956487994 scopus 로고    scopus 로고
    • Zn2+-containing protein S inhibits extrinsic FX-activating complex independently of TFPI
    • Fernandes N, Mosnier LO, Tonnu L, et al. Zn2+-containing protein S inhibits extrinsic FX-activating complex independently of TFPI. J Thromb Haemost 2010; 8: 1976-1985.
    • (2010) J Thromb Haemost , vol.8 , pp. 1976-1985
    • Fernandes, N.1    Mosnier, L.O.2    Tonnu, L.3
  • 18
    • 68549127071 scopus 로고    scopus 로고
    • Plasma protein S contains zinc essential for efficient APC-independent anticoagulant activity and binding to FXa, but not for efficient binding to TFPI
    • Heeb MJ, Prashun D, Griffin JH, et al. Plasma protein S contains zinc essential for efficient APC-independent anticoagulant activity and binding to FXa, but not for efficient binding to TFPI. FASEB J 2009; 23: 2244-2253.
    • (2009) FASEB J , vol.23 , pp. 2244-2253
    • Heeb, M.J.1    Prashun, D.2    Griffin, J.H.3
  • 20
    • 43749120255 scopus 로고    scopus 로고
    • Protein S enhances the TFPI inhibition of FXa but not its inhibition of FVIIa-tissue factor
    • Ndonwi M, Broze G, Jr. Protein S enhances the TFPI inhibition of FXa but not its inhibition of FVIIa-tissue factor. J Thromb Haemost 2008; 6: 1044-1046.
    • (2008) J Thromb Haemost , vol.6 , pp. 1044-1046
    • Ndonwi, M.1    Broze Jr., G.2
  • 21
    • 33644772164 scopus 로고    scopus 로고
    • Protein S stimulates inhibition of the tissue factor pathway by TFPI
    • Hackeng TM, Sere KM, Tans G, et al. Protein S stimulates inhibition of the tissue factor pathway by TFPI. Proc Natl Acad Sci USA 2006; 103: 3106-3111.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3106-3111
    • Hackeng, T.M.1    Sere, K.M.2    Tans, G.3
  • 22
    • 13244256858 scopus 로고    scopus 로고
    • Direct anticoagulant activity of protein S-C4b binding protein complex in Heerlen heterozygotes and normals
    • Heeb MJ, Koenen RR, Fernandez JA, et al. Direct anticoagulant activity of protein S-C4b binding protein complex in Heerlen heterozygotes and normals. J Thromb Haemost 2004; 2: 1766-1773.
    • (2004) J Thromb Haemost , vol.2 , pp. 1766-1773
    • Heeb, M.J.1    Koenen, R.R.2    Fernandez, J.A.3
  • 23
    • 0027076848 scopus 로고
    • Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles
    • Dahlbäck B, Wiedmer T, Sims PJ. Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles. Biochem 1992; 31: 12769-12777.
    • (1992) Biochem , vol.31 , pp. 12769-12777
    • Dahlbäck, B.1    Wiedmer, T.2    Sims, P.J.3
  • 24
    • 33645571094 scopus 로고    scopus 로고
    • Protein S multimers and monomers each have direct anticoagulant activity
    • Heeb MJ, Schuck P, Xu X. Protein S multimers and monomers each have direct anticoagulant activity. J Thromb Haemost 2006; 4: 385-391.
    • (2006) J Thromb Haemost , vol.4 , pp. 385-391
    • Heeb, M.J.1    Schuck, P.2    Xu, X.3
  • 25
    • 4644330243 scopus 로고    scopus 로고
    • Rapid generation of thrombin by atheroma and platelets
    • Niemetz J, Fallon JT, Harrington E, et al. Rapid generation of thrombin by atheroma and platelets. J Thromb Haemost 2004; 2: 321-326.
    • (2004) J Thromb Haemost , vol.2 , pp. 321-326
    • Niemetz, J.1    Fallon, J.T.2    Harrington, E.3
  • 26
    • 0027404562 scopus 로고
    • Binding of protein S to FVa associated with inhibition of prothrombinase that is independent of activated protein C
    • Heeb MJ, Mesters R, Tans G, et al. Binding of protein S to FVa associated with inhibition of prothrombinase that is independent of activated protein C. J Biol Chem 1993; 268: 2872-2877.
    • (1993) J Biol Chem , vol.268 , pp. 2872-2877
    • Heeb, M.J.1    Mesters, R.2    Tans, G.3
  • 27
    • 0026814124 scopus 로고
    • Is platelet protein S different from plasma protein S in human being?
    • Ozawa H, Kobayashi I, Marumo M. Is platelet protein S different from plasma protein S in human being?. Japan J Clin Med 1992; 50: 292-296.
    • (1992) Japan J Clin Med , vol.50 , pp. 292-296
    • Ozawa, H.1    Kobayashi, I.2    Marumo, M.3
  • 28
    • 0025083437 scopus 로고
    • Functional characterization of platelet-released FV and its activation by FXa and thrombin
    • Monkovic DD, Tracy PB. Functional characterization of platelet-released FV and its activation by FXa and thrombin. J Biol Chem 1990; 265: 17132-17140.
    • (1990) J Biol Chem , vol.265 , pp. 17132-17140
    • Monkovic, D.D.1    Tracy, P.B.2
  • 29
    • 0020455029 scopus 로고
    • Activation of coagulation FV by a platelet protease
    • Kane WH, Mruk JS, Majerus PW. Activation of coagulation FV by a platelet protease. J Clin Invest 1982; 70: 1092-1100.
    • (1982) J Clin Invest , vol.70 , pp. 1092-1100
    • Kane, W.H.1    Mruk, J.S.2    Majerus, P.W.3
  • 30
    • 0028344095 scopus 로고
    • Platelet coagulation FVa: The major secretory platelet phosphoprotein
    • Rand MD, Kalafatis M, Mann KG. Platelet coagulation FVa: The major secretory platelet phosphoprotein. Blood 1994; 83: 2180-2190.
    • (1994) Blood , vol.83 , pp. 2180-2190
    • Rand, M.D.1    Kalafatis, M.2    Mann, K.G.3
  • 31
    • 1642576099 scopus 로고    scopus 로고
    • Unique in vivo modifications of coagulation FV produce a physically and functionally distinct platelet-derived cofactor: Characterization of purified platelet-derived FV/Va
    • Gould WR, Silveira JR, Tracy PB. Unique in vivo modifications of coagulation FV produce a physically and functionally distinct platelet-derived cofactor: Characterization of purified platelet-derived FV/Va. J Biol Chem 2004; 279: 2383-2393.
    • (2004) J Biol Chem , vol.279 , pp. 2383-2393
    • Gould, W.R.1    Silveira, J.R.2    Tracy, P.B.3
  • 32
    • 84874718081 scopus 로고    scopus 로고
    • Phosphorylation of protein S by platelet kinases enhances its direct anticoagulant activity
    • [abstract]
    • Stavenuiter F, Heeb MJ. Phosphorylation of protein S by platelet kinases enhances its direct anticoagulant activity. J Thromb Haemost 2011; Vol 9 [abstract].
    • (2011) J Thromb Haemost , vol.9
    • Stavenuiter, F.1    Heeb, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.