Inhibition of Rac and ROCK Signalling Influence Osteoblast Adhesion, Differentiation and Mineralization on Titanium Topographies

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Prowse, Paul D H ^a   Elliott, Christopher G ^a   Hutter, Jeff ^a   Hamilton, Douglas W ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BONE MORPHOGENETIC PROTEIN 2; BONE SIALOPROTEIN; F ACTIN; MESSENGER RNA; OSTEOCALCIN; RAC PROTEIN; RAC1 PROTEIN; RHO KINASE; TITANIUM; TRANSCRIPTION FACTOR RUNX2;

ACTIVATING TRANSCRIPTION FACTOR 4 GENE; ANIMAL CELL; ARTICLE; BIOMINERALIZATION; BONE MINERALIZATION; BONE MORPHOGENETIC PROTEIN 2 GENE; BONE SIALOPROTEIN GENE; CALVARIA; CELL ADHESION; CELL DIFFERENTIATION; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; INHIBITION KINETICS; NONHUMAN; OSTEOBLAST; OSTEOCALCIN GENE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; SURFACE PROPERTY; TRANSCRIPTION FACTOR RUNX2 GENE;

ANIMALS; CALCIFICATION, PHYSIOLOGIC; CELL ADHESION; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; FOCAL ADHESIONS; HUMANS; OSTEOBLASTS; OSTEOGENESIS; PROTEASE INHIBITORS; PROTEIN TRANSPORT; RAC GTP-BINDING PROTEINS; RATS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SURFACE PROPERTIES; TITANIUM;

EID: 84874697766     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058898     Document Type: Article

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