Microglial SK3 and SK4 currents and activation state are modulated by the neuroprotective drug, riluzole

Journal of Neuroimmune Pharmacology

Volumn 8, Issue 1, 2013, Pages 227-237

  Liu, B S ^a   Ferreira, R ^a,b   Lively, S ^a   Schlichter, L C ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Alternative activation; Intracellular Ca2+; KCa2.3; KCa3.1; Microglial activation; SK channels

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM ION; CALMODULIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; RILUZOLE; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ACTIVATION; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; DRUG SELECTIVITY; MEMBRANE POTENTIAL; MICROGLIA; NERVE CELL GROWTH; NERVE CELL MEMBRANE POTENTIAL; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL LINE; INTERLEUKIN-4; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; LIPOPOLYSACCHARIDES; MICROGLIA; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RILUZOLE; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS;

EID: 84874649617     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9365-0     Document Type: Article

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