Structure-relaxivity relationships of serum albumin targeted MRI probes based on a single amino acid Gd complex

Journal of Medicinal Chemistry

Volumn 56, Issue 4, 2013, Pages 1782-1786

  Boros, Eszter ^a   Caravan, Peter ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,2',2'' [10 [2 ACETAMIDO 3 OXO 3 [( 1 PHENYLETHYL)AMINO]PROPYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [2 AMINO 3 OXO 3 [(1 PHENYLETHYL)AMINO]PROPYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [2 AMINO 3 [(2 METHOXY 2 OXOETHYL)AMINO] 3 OXOPROPYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [2 CARBOXY 2 [2 (4 ISOBUTYLPHENYL)PROPANAMIDO]ETHYL] 1,4,7,10 TETRAAZACYCLODEDOCANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [2 [2 AMINO 3 (4 HYDROXY 3,5 DIIODOPHENYL)PROPANAMIDO] 2 CARBOXYETHYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [2 [2 AMINO 3 (4 HYDROXY 3,5 DIIODOPHENYL)PROPANAMIDO] 3 OXO 3 [(1 PHENYLETHYL)AMINO]PROPYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [2 [2 AMINO 3 (4 HYDROXY 3,5 DIIODOPHENYL)PROPANAMIDO] 3 [(2 METHOXY 2 OXOETHYL)AMINO] 3 OXOPROPYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [3 [[ CARBOXY 2 (4HYDROXY 3,5DIIODOPHENYL)ETHYL]AMINO] 3 OXO 2 (2 PHENYLPROPANAMIDO)PROPYLL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2'' [10 [3 [[1 CARBOXY 2 (4 HYDROXY 3,5 DIIODOPHENYL)ETHYL]AMINO] 2 [2 (4 ISOBUTYL)PROPANAMIDO] 3 OXOPROPYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]ACETIC ACID; GADOLINIUM; HUMAN SERUM ALBUMIN; METAL COMPLEX; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; BINDING AFFINITY; CHIRALITY; COMPLEX FORMATION; DIASTEREOISOMER; HYDROGEN BOND; LIPOPHILICITY; MOLECULAR PROBE; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE IMAGING; STRUCTURE ACTIVITY RELATION;

EID: 84874625094     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4000177     Document Type: Article

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