New insights for pursuing high relaxivity MRI agents from modelling the binding interaction of GdIII chelates to HSA

ChemBioChem

Volumn 6, Issue 5, 2005, Pages 818-820

  Aime, Silvio ^a   Gianolio, Eliana ^a   Longo, Dario ^a   Pagliarin, Roberto ^b   Lovazzano, Clara ^b   Sisti, Massimo ^c  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Albumin; Chelates; Drug delivery; High relaxivity; Imaging agents; Molecular modeling

Indexed keywords

GADOLINIUM; GADOLINIUM ALPHA,ALPHA',ALPHA'',ALPHA''' TETRAMETHYL 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; GADOTERIC ACID; HUMAN SERUM ALBUMIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; CHEMICAL STRUCTURE; COMPLEX FORMATION; MACROMOLECULE; METAL BINDING; MOLECULAR IMAGING; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

CHELATING AGENTS; GADOLINIUM; HUMANS; MAGNETIC RESONANCE IMAGING; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SERUM ALBUMIN;

EID: 21044444021     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400364     Document Type: Article

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