Whole-Genome Thermodynamic Analysis Reduces siRNA Off-Target Effects

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Chen, Xi ^a   Liu, Peng ^b   Chou, Hui Hsien ^a,c  

^a IOWA STATE UNIVERSITY   (United States)

^b Iowa State University   (United States)

^c Iowa State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA;

ARTICLE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; GENE; GENE TARGETING; GENETIC SCREENING; GENOME; HUMAN; HUMAN CELL; IDH1 GENE; ITPR2 GENE; MELTING POINT; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN SECONDARY STRUCTURE; RNA SEQUENCE; SEQUENCE ALIGNMENT; THERMODYNAMICS; TRIM28 GENE;

GENE KNOCKDOWN TECHNIQUES; GENE TARGETING; GENETIC ENGINEERING; GENOME; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; ISOCITRATE DEHYDROGENASE; PREDICTIVE VALUE OF TESTS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; THERMODYNAMICS;

EID: 84874607852     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058326     Document Type: Article

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