Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: A promising radiation countermeasure

International Immunopharmacology

Volumn 15, Issue 3, 2013, Pages 557-564

  Ray, Sugata ^a   Kulkarni, Shilpa S ^a   Chakraborty, Kushal ^a   Pessu, Roli ^a   Hauer Jensen, Martin ^b   Kumar, K Sree ^a   Ghosh, Sanchita P ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Endothelial; Gamma tocotrienol; Hematopoietic; Mobilization; Progenitors; Stromal

Indexed keywords

GAMMA TOCOTRIENOL; PLERIXAFOR;

ANIMAL EXPERIMENT; ARTICLE; CELL TYPE; COLONY FORMING UNIT; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; FLOW CYTOMETRY; HEMATOPOIETIC CELL; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STEM CELL MOBILIZATION; STROMA CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION; BLOOD CELLS; CELL SEPARATION; CELLS, CULTURED; CHROMANS; COLONY-FORMING UNITS ASSAY; ENDOTHELIAL CELLS; FLOW CYTOMETRY; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HETEROCYCLIC COMPOUNDS; MICE; MICE, INBRED STRAINS; RADIATION-PROTECTIVE AGENTS; STROMAL CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITAMIN E;

EID: 84874601221     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.12.034     Document Type: Article

References (27)

1. C.M. Digirolamo, D. Stokes, D. Colter, D.G. Phinney, R. Class, and D.J. Prockop Propagation and senescence of human marrow stromal cells in culture: A simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate Br J Haematol 107 1999 275 281
2. A.M. Greenbaum, and D.C. Link Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization Leukemia 25 2011 211 217
3. I. Petit, M. Szyper-Kravitz, A. Nagler, M. Lahav, A. Peled, and L. Habler G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4 Nat Immunol 3 2002 687 694
4. I. Pusic, and J.F. DiPersio The use of growth factors in hematopoietic stem cell transplantation Curr Pharm Des 14 2008 1950 1961
5. I. Pusic, S.Y. Jiang, S. Landua, G.L. Uy, M.P. Rettig, and A.F. Cashen Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation Biol Blood Marrow Transplant 14 2008 1045 1056
6. T.J. MacVittie, and A.M. Farese Cytokine-based treatment of radiation injury: potential benefits after low-level radiation exposure Mil Med 167 2002 68 70
7. F.M. Uckun, L. Souza, K.G. Waddick, M. Wick, and C.W. Song In vivo radioprotective effects of recombinant human granulocyte colony-stimulating factor in lethally irradiated mice Blood 75 1990 638 645
8. K.G. Waddick, C.W. Song, L. Souza, and F.M. Uckun Comparative analysis of the in vivo radioprotective effects of recombinant granulocyte colony-stimulating factor (G-CSF), recombinant granulocyte-macrophage CSF, and their combination Blood 77 1991 2364 2371
9. K. Hubel, E. Rodger, J.M. Gaviria, T.H. Price, D.C. Dale, and W.C. Liles Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor Transfusion 45 2005 1876 1889
10. S.P. Ghosh, S. Kulkarni, K. Hieber, R. Toles, L. Romanyukha, and T.C. Kao Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector Int J Radiat Biol 85 2009 598 606
11. S. Kulkarni, S.P. Ghosh, M. Satyamitra, S. Mog, K. Hieber, and L. Romanyukha Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation Radiat Res 173 2010 738 747
12. S.S. Kulkarni, L.H. Cary, K. Gambles, M. Hauer-Jensen, K.S. Kumar, and S.P. Ghosh Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor Int Immunopharmacol 14 2012 495 503
13. Y.F. Cui, H. Yang, Q.L. Luo, B. Dong, X.L. Liu, and H. Xu Radioprotection of recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor on peripheral lymphocytes of rhesus monkey irradiated by 3.0 Gy gamma-rays Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 16 2004 22 25
14. M. Drouet, and F. Herodin Radiation victim management and the haematologist in the future: Time to revisit therapeutic guidelines? Int J Radiat Biol 86 2010 636 648
15. V.K. Singh, R.L. Shafran, W.E. Jackson III, T.M. Seed, and K.S. Kumar Induction of cytokines by radioprotective tocopherol analogs Exp Mol Pathol 81 2006 55 61
16. W.C. Liles, H.E. Broxmeyer, E. Rodger, B. Wood, K. Hubel, and S. Cooper Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist Blood 102 2003 2728 2730
17. H.E. Broxmeyer, C.M. Orschell, D.W. Clapp, G. Hangoc, S. Cooper, and P.A. Plett Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist J Exp Med 201 2005 1307 1318
18. W.C. Liles, E. Rodger, H.E. Broxmeyer, C. Dehner, K. Badel, and G. Calandra Augmented mobilization and collection of CD34 + hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist Transfusion 45 2005 295 300
19. S.M. Devine, N. Flomenberg, D.H. Vesole, J. Liesveld, D. Weisdorf, and K. Badel Rapid mobilization of CD34 + cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma J Clin Oncol 22 2004 1095 1102
20. N. Flomenberg, S.M. Devine, J.F. Dipersio, J.L. Liesveld, J.M. McCarty, and S.D. Rowley The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF alone Blood 106 2005 1867 1874
21. S.C. Pitchford, R.C. Furze, C.P. Jones, A.M. Wengner, and S.M. Rankin Differential mobilization of subsets of progenitor cells from the bone marrow Cell Stem Cell 4 2009 62 72
22. J.C. Voyta, D.P. Via, C.E. Butterfield, and B.R. Zetter Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein J Cell Biol 99 1984 2034 2040
23. T.J. MacVittie, A.M. Farese, W.G. Smith, C.M. Baum, E. Burton, and J.P. McKearn Myelopoietin, an engineered chimeric IL-3 and G-CSF receptor agonist, stimulates multilineage hematopoietic recovery in a nonhuman primate model of radiation-induced myelosuppression Blood 95 2000 837 845
24. N. Schmitz, M. Beksac, D. Hasenclever, A. Bacigalupo, T. Ruutu, and A. Nagler Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemia Blood 100 2002 761 767
25. T. Hideshima, C. Mitsiades, H. Ikeda, D. Chauhan, N. Raje, and G. Gorgun A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells Blood 115 2010 3772 3775
26. A. Larochelle, A. Krouse, M. Metzger, D. Orlic, R.E. Donahue, and S. Fricker AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates Blood 107 2006 3772 3778
27. C. Lange, B. Brunswig-Spickenheier, H. Cappallo-Obermann, K. Eggert, U.M. Gehling, and C. Rudolph Radiation rescue: Mesenchymal stromal cells protect from lethal irradiation PLoS One 6 2011 e14486