From single-SNP to wide-locus: Genome-wide association studies identifying functionally related genes and intragenic regions in small sample studies

Pharmacogenomics

Volumn 14, Issue 4, 2013, Pages 391-401

  Wittkowski, Knut M ^a   Sonakya, Vikas ^a   Song, Tingting ^a   Seybold, Martin P ^b   Keddache, Mehdi ^c   Durner, Martina ^d  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF STUTTGART   (Germany)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

common disease; epilepsy; epistasis; genome wide association study; GWAS; Phase III trials; Ras pathway; U statistics

Indexed keywords

ARHGAP32 GENE; ARTICLE; CHANNELOPATHY; CHILD; CHILDHOOD ABSENCE EPILEPSY; CHROMOSOMAL LOCALIZATION; CONTROLLED STUDY; EEF1A1P12 GENE; EPISTASIS; FEMALE; GAIN OF FUNCTION MUTATION; GENE CLUSTER; GENE FUNCTION; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOSOME; OPHN1 GENE; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

CLINICAL TRIALS, PHASE III AS TOPIC; EPILEPSY; EPISTASIS, GENETIC; GENOME-WIDE ASSOCIATION STUDY; HUMANS; METABOLIC NETWORKS AND PATHWAYS; POLYMORPHISM, SINGLE NUCLEOTIDE; RAS PROTEINS; STATISTICS, NONPARAMETRIC;

EID: 84874600128     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.13.28     Document Type: Article

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