Altered expression of the small guanosine triphosphatase RhoA in human temporal lobe epilepsy

Journal of Molecular Neuroscience

Volumn 42, Issue 1, 2010, Pages 53-58

  Yuan, Jie ^a   Wang, Lin Yuan ^b   Li, Jin Mei ^a   Cao, Ning Jia ^c   Wang, Liang ^a   Feng, Gui Bo ^a   Xue, Tao ^a   Lu, Yang ^a   Wang, Xue Feng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Axon growth; Neuronal loss; RhoA; Temporal lobe epilepsy

Indexed keywords

GUANOSINE TRIPHOSPHATASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; ARTICLE; BRAIN TISSUE; CELL MEMBRANE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOPLASM VESICLE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; PROTEIN EXPRESSION; TEMPORAL LOBE EPILEPSY; WESTERN BLOTTING;

ADOLESCENT; ADULT; CHILD; EPILEPSY, TEMPORAL LOBE; FEMALE; HUMANS; MALE; MIDDLE AGED; RHOA GTP-BINDING PROTEIN; TEMPORAL LOBE; YOUNG ADULT;

ANIMALIA;

EID: 77955173817     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-010-9330-4     Document Type: Article

References (24)

1. DD Armstrong 2005 Epilepsy-induced microarchitectural changes in the brain Pediatr Dev Pathol 8 607 14 10.1007/s10024-005-0054-3 16333693 G.L. Li, N. Zhang, J. Li, D.T. Zhu (Pubitemid 41830920)
2. SA Benitah PF Valerón L van Aelst CJ Marshall JC Lacal 2004 Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation Biochim Biophys Acta 1705 2 121 32 1:CAS:528:DC%2BD2cXhtVGgurvO 15588766
3. C Brabeck M Mittelbronn K Bekure R Meyermann HJ Schluesener JM Schwab 2003 Effect of focal cerebral infarctions on lesional RhoA and RhoB expression Arch Neurol 60 9 1245 1249 10.1001/archneur.60.9.1245 12975290 (Pubitemid 37099630)
4. P Dergham B Ellezam C Essagian H Avedissian WD Lubell L McKerracher 2002 Rho signaling pathway targeted to promote spinal cord repair J Neurosci 22 6570 6577 1:CAS:528:DC%2BD38XlvFKnsbY%3D 12151536
5. CI Dubreuil N Marklund K Deschamps TK McIntosh L McKerracher 2006 Activation of Rho after traumatic brain injury and seizure in rats Exp Neurol 198 361 369 10.1016/j.expneurol.2005.12.002 1:CAS:528:DC%2BD28Xjs1ajt7c%3D 16448651
6. AE Fournier BT Takizawa SM Strittmatter 2003 Rho kinase inhibition enhances axonal regeneration in the injured CNS J. Neurosci 23 4 1416 1423 1:CAS:528:DC%2BD3sXit1antbs%3D 12598630
7. Michael Frotscher Peter Jonas RS Sloviter 2006 Synapses formed by normal and abnormal hippocampal mossy fibers Cell Tissue Res 326 361 7 10.1007/s00441-006-0269-2 16819624 (Pubitemid 44435813)
8. A Hall 1998 Rho GTPases J Biol Chem 273 20685 20688 10.1074/jbc.273.33. 20685 9694808 (Pubitemid 28385341)
9. IE Holopainen 2008 Seizures in the developing brain: cellular and molecular mechanisms of neuronal damage, neurogenesis and cellular reorganization Neurochem Int 52 935 47 10.1016/j.neuint.2007.10.021 1:CAS:528:DC%2BD1cXktVKltb0%3D 18093696
10. S Inan K Buyukafsar 2008 Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice Br J Pharmacol 155 44 51 10.1038/bjp.2008.225 1:CAS:528:DC%2BD1cXhtVagsLnJ 18536751
11. International League Against Epilepsy 1981 Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy Epilepsia 22 4 489 501 10.1111/j.1528-1157.1981.tb06159.x
12. SW Kim YM Yu CS Piao JB Kim JK Lee 2004 Inhibition of delayed induction of p38 mitogen-activated protein kinase attenuates kainic acid-induced neuronal loss in the hippocampus Brain Res 1007 188 91 10.1016/j.brainres.2004.02.009 1:CAS:528:DC%2BD2cXivVWltbs%3D 15064151 (Pubitemid 38520188)
13. M Lehmann A Fournier I Selles-Navarro P Dergham A Sebok N Leclerc G Tigyi L McKerracher 1999 Inactivation of Rho signaling pathway promotes CNS axon regeneration J Neurosci 19 7537 7547 1:CAS:528:DyaK1MXlslWms7s%3D 10460260
14. H Lin LW Wu YG Huang YC Chen YC Chen XN Wen 2007 Correlation between hippocampal mossy fiber sprouting and synaptic reorganization and mechanisms of temporal lobe epilepsy Zhonghua Yi Xue Za Zhi 87 341 4 1:CAS:528: DC%2BD1cXntFCju78%3D 17456365
15. FY Liu XF Wang MW Li JM Li ZQ Xi GM Luan GM Zhang JG Zhang YP Wang JJ Sun YL Li 2007 Upregulated expression of postsynaptic density-93 and n-methyl-d-aspartate receptors subunits 2B mRNA in temporal lobe tissue of epilepsy Biochem Biophys Res Commun 358 825 30 10.1016/j.bbrc.2007.05.010 1:CAS:528:DC%2BD2sXlvV2qtrw%3D 17506987 (Pubitemid 46805155)
16. S Narumiya T Ishizaki M Uehata 2000 Use and properties of ROCK- specific inhibitor Y-27632 Methods Enzymol 325 273 84 10.1016/S0076-6879(00)25449-9 1:CAS:528:DC%2BD3cXot1ajtr8%3D 11036610
17. Manabu Negishi Hironori Katoh 2002 Rho family GTPases as key regulators for neuronal network formation J Biochem 132 157 166 1:CAS:528: DC%2BD38XnsV2ksr0%3D 12153710
18. PP Rickham 1964 Human experimentation code of ethics of the World Medical Association, Declaration of Helisinki Br Med J 2 177 179 10.1136/bmj.2.5402.177 1:STN:280:DyaF2c7gvVygsA%3D%3D 14150898
19. NM Rubenstein JA Callahan DH Lo GL Firestone 2007 Selective glucocorticoid control of Rho kinase isoforms regulate cell-cell interactions Biochem Biophys Res Commun 354 603 7 10.1016/j.bbrc.2007.01.024 1:CAS:528:DC%2BD2sXhtlOgtb0%3D 17240358 (Pubitemid 46161368)
20. TP Sutula A Dudek 2007 Unmasking recurrent excitation generated by mossy fiber sprouting in the epileptic dentate gyrus: an emergent property of a complex system Prog Brain Res 163 541 63 10.1016/S0079-6123(07)63029-5 1:CAS:528:DC%2BD1cXls1Oktw%3D%3D 17765737 (Pubitemid 47321452)
21. H-R Wang V Zhang B Ozdamar AA Ogunjimi E Alexandrova GH Thomsen JL Wrana 2003 Regulation of cell polarity and protrusion formation by targeting RhoA for degradation Science 302 1690 1 10.1126/science.1092874 (Pubitemid 37505719)
22. K Wong XR Ren YZ Huang Y Xie G Liu H Saito H Tang L Wen SM Brady-Kalnay L Mei JY Wu WC Xiong Y Rao 2001 Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the slit-robo pathway Cell 107 209 21 10.1016/S0092-8674(01)00530-X 1:CAS:528: DC%2BD3MXotVSnt74%3D 11672528 (Pubitemid 33035947)
23. F Xiao XF Wang JM LI ZQ Xi Y Lu L Wang Y Zeng LF Guan J Yuan 2008 Overexpression of N-WASP in the brain of human epilepsy Brain Res 1233 168 75 10.1016/j.brainres.2008.07.101 1:CAS:528:DC%2BD1cXhtFWlt73L 18708039
24. XB Yuan M Jin X Xu YQ Song CP Wu MM Poo S Duan 2003 Signalling and crosstalk of Rho GTPases in mediating axon guidance Nat Cell Biol 5 38 45 10.1038/ncb895 1:CAS:528:DC%2BD3sXivFCg 12510192 (Pubitemid 36054327)