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Volumn 308, Issue 18, 2012, Pages 1867-1868

The promise and limitations of genome-wide association studies

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT FACTOR H; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SERINE PROTEINASE;

EID: 84868631803     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/2012.jama.10823     Document Type: Short Survey
Times cited : (27)

References (10)
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    • Hindorff LA, Sethupathy P, Junkins HA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A. 2009;106(23):9362-9367.
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    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3
  • 3
    • 75749155367 scopus 로고    scopus 로고
    • Accessed May 30, 2012
    • National Human Genome Research Institute. Genome-wide association studies. http://www.genome.gov/20019523. Accessed May 30, 2012.
    • Genome-wide Association Studies
  • 4
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in agerelated macular degeneration
    • Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in agerelated macular degeneration. Science. 2005;308(5720):385-389.
    • (2005) Science , vol.308 , Issue.5720 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 5
    • 79951811351 scopus 로고    scopus 로고
    • Imputation of sequence variants for identification of genetic risks for Parkinson's disease: A meta-analysis of genome-wide association studies
    • International Parkinson Disease Genomics Consortium
    • Nalls MA, Plagnol V, Hernandez DG, et al; International Parkinson Disease Genomics Consortium. Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet. 2011;377(9766):641-649.
    • (2011) Lancet , vol.377 , Issue.9766 , pp. 641-649
    • Nalls, M.A.1    Plagnol, V.2    Hernandez, D.G.3
  • 6
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    • From GWAS to clinical utility in Parkinson's disease
    • Klein C, Ziegler A. From GWAS to clinical utility in Parkinson's disease. Lancet. 2011;377(9766):613-614.
    • (2011) Lancet , vol.377 , Issue.9766 , pp. 613-614
    • Klein, C.1    Ziegler, A.2
  • 7
    • 79959689333 scopus 로고    scopus 로고
    • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
    • PSP Genetics Study Group
    • Höglinger GU, Melhem NM, Dickson DW, et al; PSP Genetics Study Group. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat Genet. 2011;43(7):699-705.
    • (2011) Nat Genet , vol.43 , Issue.7 , pp. 699-705
    • Höglinger, G.U.1    Melhem, N.M.2    Dickson, D.W.3
  • 8
    • 84859339977 scopus 로고    scopus 로고
    • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database
    • Lill CM, Roehr JT, McQueen MB, et al. Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet. 2012;8(3):e1002548.
    • (2012) PLoS Genet , vol.8 , Issue.3
    • Lill, C.M.1    Roehr, J.T.2    McQueen, M.B.3
  • 9
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    • Knowledgedriven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations
    • Ma L, Brautbar A, Boerwinkle E, Sing CF, Clark AG, Keinan A. Knowledgedriven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations. PLoS Genet. 2012;8(5):e1002714.
    • (2012) PLoS Genet , vol.8 , Issue.5
    • Ma, L.1    Brautbar, A.2    Boerwinkle, E.3    Sing, C.F.4    Clark, A.G.5    Keinan, A.6
  • 10
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    • Fine mapping of five loci associated with lowdensity lipoprotein cholesterol detects variants that double the explained heritability
    • Sanna S, Li B, Mulas A, et al. Fine mapping of five loci associated with lowdensity lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet. 2011;7(7):e1002198.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.