An inherited heteroplasmic mutation in mitochondrial gene COI in a patient with prostate cancer alters reactive oxygen, reactive nitrogen and proliferation

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Arnold, Rebecca S ^a,b   Sun, Qian ^a   Sun, Carrie Q ^a   Richards, Jendai C ^a   O'Hearn, Sean ^c   Osunkoya, Adeboye O ^a,b,d   Wallace, Douglas C ^c,e   Petros, John A ^a,b,d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ATLANTA VA MEDICAL CENTER   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME; CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE SUBUNIT 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOCHONDRIAL DNA; NEURONAL NITRIC OXIDE SYNTHASE; PROSTATE SPECIFIC ANTIGEN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER PATIENT; CASE REPORT; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; FOLLOW UP; GENE FUNCTION; GLEASON SCORE; HETEROPLASMY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LASER MICRODISSECTION; MALE; MISSENSE MUTATION; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PROSTATE ADENOCARCINOMA; WESTERN BLOTTING; ANIMAL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; MITOCHONDRIAL GENE; MITOCHONDRION; MUTATION; PROSTATE TUMOR;

ANIMALS; CELL PROLIFERATION; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MITOCHONDRIAL; HUMANS; MALE; MICE; MIDDLE AGED; MITOCHONDRIA; MUTATION; PROSTATIC NEOPLASMS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

EID: 84874597251     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/239257     Document Type: Article

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