Arabidopsis ubiquitin ligase MIEL1 mediates degradation of the transcription factor MYB30 weakening plant defence

Nature Communications

Volumn 4, Issue , 2013, Pages

  Marino, Daniel ^a,c,d   Froidure, Solene ^a   Canonne, Joanne ^a   Khaled, Sara Ben ^a,e   Khafif, Mehdi ^a   Pouzet, Cécile ^b   Jauneau, Alain ^b   Roby, Dominique ^a   Rivas, Susana ^a  

^a LABORATOIRE DES INTERACTIONS PLANTES MICROORGANISMES LIPM   (France)

^b Fédération de Recherche 3450 Agrobiosciences Interactions et Biodiversités   (France)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d BASQUE FOUNDATION FOR SCIENCE   (Spain)

^e SAINSBURY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MYB30 INTERACTING E3 LIGASE1; TRANSCRIPTION FACTOR; TRASCRIPTION FACTOR MYB30; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

APOPTOSIS; BACTERIUM; BIODEGRADATION; DICOTYLEDON; DISEASE RESISTANCE; ENZYME ACTIVITY; FUNCTIONAL ROLE; GENE EXPRESSION; INOCULATION; PHYTOCHEMISTRY; PLANT DEFENSE; PROTEIN;

ARABIDOPSIS; ARTICLE; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; DOWN REGULATION; INOCULATION; NONHUMAN; PLANT DEFENSE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UBIQUITINATION;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CELL NUCLEUS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION, PLANT; MICROSCOPY, CONFOCAL; PLANT CELLS; PLANT DISEASES; PLANT EPIDERMIS; PLANTS, GENETICALLY MODIFIED; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEOLYSIS; PSEUDOMONAS SYRINGAE; TOBACCO; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84874590693     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2479     Document Type: Article

References (32)

1. Coll, N. S., Epple, P. & Dangl, J. L. Programmed cell death in the plant immune system. Cell Death Differ. 18, 1247-1256 (2011)
2. Moore, J. W., Loake, G. J. & Spoel, S. H. Transcription dynamics in plant immunity. Plant Cell 23, 2809-2820 (2011)
3. Vailleau, F. et al. A R2R3-MYB gene, AtMYB30, acts as a positive regulator of the hypersensitive cell death program in plants in response to pathogen attack. Proc. Natl Acad. Sci. USA 99, 10179-10184 (2002) (Pubitemid 34831192)
4. Raffaele, S. et al. A MYB transcription factor regulates very-long-chain fatty acid biosynthesis for activation of the hypersensitive cell death response in Arabidopsis. Plant Cell 20, 752-767 (2008) (Pubitemid 352844005)
5. Canonne, J. et al. The Xanthomonas type III effector XopD targets the Arabidopsis transcription factor AtMYB30 to suppress plant defence. Plant Cell 23, 3498-3511 (2011)
6. Vierstra, R. D. The ubiquitin-26S proteasome system at the nexus of plant biology. Nat. Rev. Mol. Cell Biol. 10, 385-397 (2009)
7. Downes, B. P., Stupar, R. M., Gingerich, D. J. & Vierstra, R. D. The HECT ubiquitin-protein ligase (UPL) family in Arabidopsis: UPL3 has a specific role in trichome development. Plant J. 35, 729-742 (2003) (Pubitemid 37143720)
8. Stone, S. L. et al. Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis. Plant Physiol. 137, 13-30 (2005) (Pubitemid 43034286)
9. Yee, D. & Goring, D. R. The diversity of plant U-box E3 ubiquitin ligases: from upstream activators to downstream target substrates. J. Exp. Bot. 60, 1109-1121 (2009)
10. Mazzucotelli, E. et al. The E3 ubiquitin ligase gene family in plants: regulation by degradation. Curr. Genomics 7, 509-522 (2006) (Pubitemid 46062382)
11. Froidure, S. et al. AtsPLA2-alpha nuclear relocalization by the Arabidopsis transcription factor AtMYB30 leads to repression of the plant defense response. Proc. Natl Acad. Sci. USA 107, 15281-15286 (2010)
12. Nesi, N., Jond, C., Debeaujon, I., Caboche, M. & Lepiniec, L. The Arabidopsis TT2 gene encodes an R2R3-MYB domain protein that acts as a key determinant for proanthocyanidin accumulation in developing seed. Plant Cell 13, 2099-2114 (2001) (Pubitemid 32925416)
13. Hjerpe, R. et al. Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities. EMBO Rep. 10, 1250-1258 (2009)
14. Marino, D., Peeters, N. & Rivas, S. Ubiquitination during plant immune signaling. Plant Physiol. 160, 15-27 (2012)
15. Trujillo, M. & Shirasu, K. Ubiquitination in plant immunity. Curr. Opin. Plant Biol. 13, 402-408 (2010)
16. Robert-Seilaniantz, A., Grant, M. & Jones, J. D. Hormone crosstalk in plant disease and defense: more than just JASMONATE-SALICYLATE antagonism. Annu. Rev. Phytopathol. 49, 317-343 (2011)
17. Lu, D. et al. Direct ubiquitination of pattern recognition receptor FLS2 attenuates plant innate immunity. Science 332, 1439-1442 (2011)
18. Cheng, Y. T. et al. Stability of plant immune-receptor resistance proteins is controlled by SKP1-CULLIN1-F-box (SCF)-mediated protein degradation. Proc. Natl Acad. Sci. USA 108, 14694-14699 (2011)
19. Gou, M. et al. The F-box protein CPR1/CPR30 negatively regulates R protein SNC1 accumulation. Plant J. 69, 411-420 (2012)
20. Wang, Y. S. et al. Rice XA21 binding protein 3 is a ubiquitin ligase required for full Xa21-mediated disease resistance. Plant Cell 18, 3635-3646 (2006)
21. Hammond-Martel, I., Yu, H. & Affar el, B. Roles of ubiquitin signaling in transcription regulation. Cell Signal 24, 410-421 (2012)
22. Durrant, W., Rowland, O., Piedras, P., Hammond-Kosack, K. & Jones, J. cDNA-AFLP reveals a striking overlap in race-specific resistance and wound response gene expression profiles. Plant Cell 12, 963 (2000)
23. Navarro, L. et al. The transcriptional innate immune response to flg22. Interplay and overlap with Avr gene-dependent defense responses and bacterial pathogenesis. Plant Physiol. 135, 1113-1128 (2004) (Pubitemid 38819053)
24. Ramonell, K. et al. Loss-of-function mutations in chitin responsive genes show increased susceptibility to the powdery mildew pathogen Erysiphe cichoracearum. Plant Physiol. 138, 1027-1036 (2005) (Pubitemid 43793178)
25. Zipfel, C. et al. Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation. Cell 125, 749-760 (2006)
26. Mengiste, T., Chen, X., Salmeron, J. & Dietrich, R. The BOTRYTIS SUSCEPTIBLE1 gene encodes an R2R3MYB transcription factor protein that is required for biotic and abiotic stress responses in Arabidopsis. Plant Cell 15, 2551-2565 (2003) (Pubitemid 37470657)
27. Luo, H. et al. The Arabidopsis Botrytis Susceptible1 Interactor defines a subclass of RING E3 ligases that regulate pathogen and stress responses. Plant Physiol. 154, 1766-1782 (2010)
28. Meek, D. W. & Anderson, C. W. Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harb. Perspect. Biol. 1, a000950 (2009)
29. Luscher, B. & Vervoorts, J. Regulation of gene transcription by the oncoprotein MYC. Gene 494, 145-160 (2012)
30. Lorrain, S., Vailleau, F., Balagué, C. & Roby, D. Lesion mimic mutants: keys for deciphering cell death and defense pathways in plants? Trends Plant Sci. 8, 263-271 (2003) (Pubitemid 36837376)
31. Raffaele, S., Rivas, S. & Roby, D. An essential role for salicylic acid in AtMYB30-mediated control of the hypersensitive cell death program in Arabidopsis. FEBS Lett. 580, 3498-3504 (2006) (Pubitemid 43795921)
32. Marion, J. et al. Systematic analysis of protein subcellular localization and interaction using high-throughput transient transformation of Arabidopsis seedlings. Plant J. 56, 169-179 (2008).