Molecular dynamics of drug crystal dissolution: Simulation of acetaminophen form I in water

Molecular Pharmaceutics

Volumn 10, Issue 3, 2013, Pages 905-917

  Gao, Yi ^a,b   Olsen, Kenneth W ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b ABBVIE INC   (United States)

Author keywords

acetaminophen; corner and edge effect; crystal form; dissolution; electrostatic and van der Waals; molecular dynamics simulation

Indexed keywords

PARACETAMOL; SOLVENT; WATER;

ARTICLE; CRYSTAL; DRUG SOLUBILITY; ENERGY; FORCE; MICROSCOPY; MOLECULAR DYNAMICS; PARTICLE SIZE; PRIORITY JOURNAL;

EID: 84874587913     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4000212     Document Type: Article

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