VEGFR2 functions as an H2S-targeting receptor protein kinase with its novel Cys1045-Cys1024 disulfide bond serving as a specific molecular switch for hydrogen sulfide actions in vascular endothelial cells

Antioxidants and Redox Signaling

Volumn 19, Issue 5, 2013, Pages 448-464

  Tao, Bei Bei ^a,b   Liu, Shu Yuan ^a   Zhang, Cai Cai ^a   Fu, Wei ^b   Cai, Wen Jie ^c   Wang, Yi ^b   Shen, Qing ^b   Wang, Ming Jie ^a   Chen, Ying ^a   Zhang, Li Jia ^a   Zhu, Yi Zhun ^b   Zhu, Yi Chun ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTATHIONINE GAMMA LYASE; HYDROGEN SULFIDE; SMALL INTERFERING RNA; VASCULOTROPIN RECEPTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CELL GROWTH; CELL HYPOXIA; CELL MIGRATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; DISULFIDE BOND; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; INTRACELLULAR SIGNALING; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TANDEM MASS SPECTROMETRY; ANIMAL; C57BL MOUSE; CHEMISTRY; CONFOCAL MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MUTATION;

MUS;

ANIMALS; CYSTATHIONINE GAMMA-LYASE; ENDOTHELIAL CELLS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYDROGEN SULFIDE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MOLECULAR DYNAMICS SIMULATION; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84874575518     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4565     Document Type: Article

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