Treatment with 670 nm Light Up Regulates Cytochrome C Oxidase Expression and Reduces Inflammation in an Age-Related Macular Degeneration Model

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Begum, Rana ^a   Powner, Michael B ^a   Hudson, Natalie ^a   Hogg, Chris ^a,b   Jeffery, Glen ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; CYTOCHROME C OXIDASE; GLIAL FIBRILLARY ACIDIC PROTEIN; VIMENTIN;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; IMMUNOHISTOCHEMISTRY; LIGHT EXPOSURE; MACROPHAGE FUNCTION; MOUSE; MUELLER CELL; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE PHOSPHORYLATION; PHOTOTHERAPY; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATION; LIGHT; MACROPHAGES; MACULAR DEGENERATION; MICE; OXIDATIVE STRESS; PHOTOTHERAPY; RETINA; UP-REGULATION;

EID: 84874559855     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057828     Document Type: Article

References (53)

1. Alonso-Fernández P, De la Fuente M, (2011) Role of the immune system in aging and longevity. Curr Aging Sci 4: 78-100.
2. Hoh Kam J, Lenassi E, Jeffery G, (2010) Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages. PLoS One 5: e13127.
3. Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, et al. (2010) The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 29: 95-112.
4. Graymore CN, Kissun RD, (1969) Use of phenazine methosulphate (PMS) in the histochemical localization of lactic acid dehydrogenase (LDH) in the retina. Exp Eye Res 8: 375-8.
5. Barot M, Gokulgandhi MR, Mitra AK, (2011) Mitochondrial dysfunction in retinal diseases. Curr Eye Res 36: 1069-77.
6. Liang FQ, Godley BF, (2003) Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration. Exp Eye Res 76: 397-403.
7. Kokkinopoulos I, Colman A, Hogg C, Heckenlively J, Jeffery G, (2013) Age-related retinal inflammation is reduced by 670 nm light via increased mitochondrial membrane potential. Neurobiol Aging 34: 602-9.
8. Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY, (2012) Age-related macular degeneration. Lancet 5 379: 1728-38.
9. Hageman GS, Gehrs K, Johnson LV, Anderson D (2008) Age-Related Macular Degeneration (AMD). In: Kolb H, Fernandez E, Nelson R, editors. Webvision: The Organization of the Retina and Visual System [Internet]. Salt Lake City, UT: University of Utah Health Sciences Center; 1995.
10. Cook HL, Patel PJ, Tufail A, (2008) Age-related macular degeneration: diagnosis and management. Br Med Bull 85: 127-49.
11. Tang J, Kern TS, (2011) Inflammation in diabetic retinopathy. Prog Retin Eye Res 30: 343-58.
12. Yeh S, Wroblewski K, Buggage R, Li Z, Kurup SK, et al. (2008) High-dose humanized anti-IL-2 receptor alpha antibody (daclizumab) for the treatment of active, non-infectious uveitis. J Autoimmun 31: 91-7.
13. Cunea A, Jeffery G, (2007) The ageing photoreceptor. Vis Neurosci 24: 151-5.
14. Jackson GR, Owsley C, Curcio CA, (2002) Photoreceptor degeneration and dysfunction in aging and age-related maculopathy. Ageing Res Rev 1: 381-96.
15. Freund PR, Watson J, Gilmour GS, Gaillard F, Sauvé Y, (2011) Differential changes in retina function with normal aging in humans. Doc Ophthalmol 122: 177-90.
16. Feher J, Kovacs I, Artico M, Cavallotti C, Papale A, et al. (2006) Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration. Neurobiol Aging 27: 983-93.
17. Lim J, Ali ZM, Sanders RA, Snyder AC, Eells JT, et al. (2009) Effects of low-level light therapy on hepatic antioxidant defense in acute and chronic diabetic rats. J Biochem Mol Toxicol 23: 1-8.
18. Wong-Riley MT, Bai X, Buchmann E, Whelan HT, (2001) Light-emitting diode treatment reverses the effect of TTX on cytochrome oxidase in neurons. Neuroreport 12: 3033-7.
19. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, et al. (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308: 419-21.
20. Edwards AO, Ritter R III, Abel KJ, Manning A, Panhuysen C, et al. (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308: 421-4.
21. Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308: 385-9.
22. Coffey PJ, Gias C, McDermott CJ, Lundh P, Pickering MC, et al. (2007) Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proc Natl Acad Sci U S A 104: 16651-6.
23. Lundh von Leithner P, Kam JH, Bainbridge J, Catchpole I, Gough G, et al. (2009) Complement factor h is critical in the maintenance of retinal perfusion. Am J Pathol 175: 412-21.
24. Catchpole IR, Germaschewski V, Ford S, Gough G, Overend P, (2011) Systemic Administration Of An Anti-amyloid Beta Monoclonal Antibody Interferes With The Ocular Pathology Of A Mouse Model Of Age-related Macular Degeneration (AMD)/Retinal Dysfunction, ARVO Meeting Abstracts 2011. 262: 1778.
25. Eells JT, Henry MM, Summerfelt P, Wong-Riley MT, Buchmann EV, et al. (2003) Therapeutic photobiomodulation for methanol-induced retinal toxicity. Proc Natl Acad Sci U S A 100: 3439-44.
26. Anderson DH, Mullins RF, Hageman GS, Johnson LV, (2002) A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 134: 411-31.
27. Anderson DH, Talaga KC, Rivest AJ, Barron E, Hageman GS, et al. (2004) Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration. Exp Eye Res 78: 243-56.
28. Chong NH, Keonin J, Luthert PJ, Frennesson CI, Weingeist DM, et al. (2005) Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration. Am J Pathol 166: 241-51.
29. Peirson SN, Butler JN, Foster RG, (2003) Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res 31: e73.
30. Lee V, Rekhi E, Hoh Kam J, Jeffery G, (2012) Vitamin D rejuvenates aging eyes by reducing inflammation, clearing amyloid beta and improving visual function. Neurobiol Aging 33: 2382-9.
31. Karu T, (1999) Primary and secondary mechanisms of action of visible to near-IR radiation on cells. J Photochem Photobiol B 49: 1-17.
32. Lane N, (2006) Cell biology: power games. Nature 443: 901-3.
33. Albarracin R, Eells J, Valter K, (2011) Photobiomodulation protects the retina from light-induced photoreceptor degeneration. Invest Ophthalmol Vis Sci 52: 3582-92.
34. Fitzgerald M, Bartlett CA, Payne SC, Hart NS, Rodger J, et al. (2010) Near infrared light reduces oxidative stress and preserves function in CNS tissue vulnerable to secondary degeneration following partial transection of the optic nerve. J Neurotrauma 27: 2107-19.
35. De Taboada L, Yu J, El-Amouri S, Gattoni-Celli S, Richieri S, et al. (2011) Transcranial laser therapy attenuates amyloid-β peptide neuropathology in amyloid-β protein precursor transgenic mice. J Alzheimers Dis 23: 521-35.
36. Shaw VE, Spana S, Ashkan K, Benabid AL, Stone J, et al. (2010) Neuroprotection of midbrain dopaminergic cells in MPTP-treated mice after near-infrared light treatment. J Comp Neurol 518: 25-40.
37. Liang HL, Whelan HT, Eells JT, Wong-Riley MT, (2008) Near-infrared light via light-emitting diode treatment is therapeutic against rotenone- and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity. Neuroscience 153(4): 963-74.
38. Lim J, Sanders RA, Snyder AC, Eells JT, Henshel DS, et al. (2010) Effects of low-level light therapy on streptozotocin-induced diabetic kidney. J Photochem Photobiol B 99: 105-10.
39. Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, et al. (2001) Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg 19: 305-14.
40. Harman D, (1956) Aging: a theory based on free radical and radiation chemistry. J. Gerontol 11: 298-300.
41. Curcio CA, Millican CL, Allen KA, Kalina RE, (1993) Aging of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina. Invest Ophthalmol Vis Sci 34: 3278-96.
42. Wong-Riley MT, Liang HL, Eells JT, Chance B, Henry MM, et al. (2005) Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: Role of cytochrome c oxidase. J Biol Chem 280: 4761-71.
43. Passarella S, Casamassima E, Molinari S, Pastore D, Quagliariello E, et al. (1984) Increase of proton electrochemical potential and ATP synthesis in rat liver mitochondria irradiated in vitro by helium-neon laser. FEBS Lett 175: 95-9.
44. Pastore D, Fratianni A, Di Pede S, Passarella S, (2000) Effects of fatty acids, nucleotides and reactive oxygen species on durum wheat mitochondria. FEBS Lett 470: 88-92.
45. Albarracin R, Valter K, (2012) 670 nm red light preconditioning supports Müller cell function: evidence from the white light-induced damage model in the rat retina. Photochem Photobiol 88: 1418-27.
46. Holz FG, Pauleikhoff D, Klein R, Bird AC, (2004) Pathogenesis of lesions in late age-related macular disease. Am J Ophthalmol. 137: 504-10.
47. Lutty G, Grunwald J, Majji AB, Uyama M, Yoneya S, (1999) Changes in choriocapillaris and retinal pigment epithelium in age-related macular degeneration. Mol Vis 5: 35.
48. Sarks SH, (1976) Ageing and degeneration in the macular region: a clinico-pathological study. Br J Ophthalmol 60: 324-41.
49. Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, et al. (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440: 352-7.
50. Chiang PK, Lam MA, Luo Y, (2008) The many faces of amyloid beta in Alzheimer's disease. Curr Mol Med 8: 580-4.
51. Parihar MS, Brewer GJ, (2010) Amyloid-β as a modulator of synaptic plasticity. J Alzheimers Dis 22: 741-63.
52. Puzzo D, Privitera L, Palmeri A, (2012) Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory. Neurobiol Aging 33 1484: e15-24.
53. Merry G, Dotson R, Devenyi R, Markowitz S, Reyes S, (2012) Photobiomodulation as a New Treatment for Dry Age Related Macular Degeneration. Results from the Toronto and Oak Ridge Photobimodulation Study in AMD (TORPA), ARVO Meeting Abstracts 2012 53: 2049.