Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Journal of Affective Disorders

Volumn 146, Issue 1, 2013, Pages 91-99

  Peyrot, Wouter J ^a   Middeldorp, Christel M ^a,b,c   Jansen, Rick ^a   Smit, Johannes H ^a   De Geus, Eco J C ^b   Hottenga, Jouke Jan ^b   Willemsen, Gonneke ^b   Vink, Jacqueline M ^b   Virding, Susanne ^d   Barragan, Isabel ^d   Ingelman Sundberg, Magnus ^d   Sim, Sarah C ^d   Boomsma, Dorret I ^a,b   Penninx, Brenda W J H ^a,e,f  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

5 HTTLPR; Course; Depression; Environment; Interaction; SERT

Indexed keywords

SEROTONIN TRANSPORTER; SEROTONIN TRANSPORTER LINKED POLYMORPHIC REGION; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EDUCATIONAL STATUS; ENVIRONMENTAL FACTOR; FEMALE; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HUMAN; LIFE EVENT; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MENTAL STRESS; NETHERLANDS; PRIORITY JOURNAL; PSYCHOTRAUMA; SEXUAL ABUSE; SINGLE NUCLEOTIDE POLYMORPHISM; SUICIDE;

ADULT; ADULT SURVIVORS OF CHILD ABUSE; CASE-CONTROL STUDIES; DEPRESSIVE DISORDER, MAJOR; EDUCATIONAL STATUS; FEMALE; GENE-ENVIRONMENT INTERACTION; HAPLOTYPES; HUMANS; LIFE CHANGE EVENTS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NETHERLANDS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; RISK FACTORS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEX OFFENSES;

EID: 84874533206     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2012.08.044     Document Type: Article

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