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Volumn 138, Issue 23, 2011, Pages 5157-5166

The astrocyte-expressed integrin αvβ8 governs blood vessel sprouting in the developing retina

Author keywords

Blood retinal barrier; Cell adhesion; Extracellular matrix; Itgb8; Mouse; Ngiogenesis

Indexed keywords

ALPHAVBETA8 INTEGRIN; RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 80755152972     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.069153     Document Type: Article
Times cited : (56)

References (49)
  • 1
    • 66449123068 scopus 로고    scopus 로고
    • The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
    • Benedito, R., Roca, C., Sorensen, I., Adams, S., Gossler, A., Fruttiger, M. and Adams, R. H. (2009). The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137, 1124-1135.
    • (2009) Cell , vol.137 , pp. 1124-1135
    • Benedito, R.1    Roca, C.2    Sorensen, I.3    Adams, S.4    Gossler, A.5    Fruttiger, M.6    Adams, R.H.7
  • 2
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin, L. E., Hemo, I. and Keshet, E. (1998). A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125, 1591-1598.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.E.1    Hemo, I.2    Keshet, E.3
  • 3
    • 19544368642 scopus 로고    scopus 로고
    • Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: An angiogenic control switch
    • Cambier, S., Gline, S., Mu, D., Collins, R., Araya, J., Dolganov, G., Einheber, S., Boudreau, N. and Nishimura, S. L. (2005). Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch. Am. J. Pathol. 166, 1883-1894.
    • (2005) Am. J. Pathol , vol.166 , pp. 1883-1894
    • Cambier, S.1    Gline, S.2    Mu, D.3    Collins, R.4    Araya, J.5    Dolganov, G.6    Einheber, S.7    Boudreau, N.8    Nishimura, S.L.9
  • 4
    • 33947308503 scopus 로고    scopus 로고
    • Retinopathy of prematurity
    • Chen, J. and Smith, L. E. (2007). Retinopathy of prematurity. Angiogenesis 10, 133-140.
    • (2007) Angiogenesis , vol.10 , pp. 133-140
    • Chen, J.1    Smith, L.E.2
  • 5
    • 0036199441 scopus 로고    scopus 로고
    • Conditional inactivation of the TGF-beta type II receptor using Cre:Lox
    • Chytil, A., Magnuson, M. A., Wright, C. V. and Moses, H. L. (2002). Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis 32, 73-75.
    • (2002) Genesis , vol.32 , pp. 73-75
    • Chytil, A.1    Magnuson, M.A.2    Wright, C.V.3    Moses, H.L.4
  • 6
    • 2642583350 scopus 로고    scopus 로고
    • Wnt signaling: Ig-norrin the dogma
    • Clevers, H. (2004). Wnt signaling: Ig-norrin the dogma. Curr. Biol. 14, R436-R437.
    • (2004) Curr. Biol , vol.14
    • Clevers, H.1
  • 8
    • 33646869290 scopus 로고    scopus 로고
    • Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina
    • Dorrell, M. I. and Friedlander, M. (2006). Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina. Prog. Retin. Eye Res. 25, 277-295.
    • (2006) Prog. Retin. Eye Res , vol.25 , pp. 277-295
    • Dorrell, M.I.1    Friedlander, M.2
  • 9
    • 33947330375 scopus 로고    scopus 로고
    • Development of the retinal vasculature
    • Fruttiger, M. (2007). Development of the retinal vasculature. Angiogenesis 10, 77-88.
    • (2007) Angiogenesis , vol.10 , pp. 77-88
    • Fruttiger, M.1
  • 13
    • 58249091885 scopus 로고    scopus 로고
    • VEGF and Notch signaling: The yin and yang of angiogenic sprouting
    • Hellstrom, M., Phng, L. K. and Gerhardt, H. (2007). VEGF and Notch signaling: the yin and yang of angiogenic sprouting. Cell Adhes. Migr. 1, 133-136.
    • (2007) Cell Adhes. Migr , vol.1 , pp. 133-136
    • Hellstrom, M.1    Phng, L.K.2    Gerhardt, H.3
  • 14
    • 33745568300 scopus 로고    scopus 로고
    • Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2
    • Hirrlinger, P. G., Scheller, A., Braun, C., Hirrlinger, J. and Kirchhoff, F. (2006). Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2. Glia 54, 11-20.
    • (2006) Glia , vol.54 , pp. 11-20
    • Hirrlinger, P.G.1    Scheller, A.2    Braun, C.3    Hirrlinger, J.4    Kirchhoff, F.5
  • 16
    • 78650364449 scopus 로고    scopus 로고
    • Beta8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart
    • Jung, Y., Kissil, J. L. and McCarty, J. H. (2010). beta8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart. Dev. Dyn. 240, 271-277.
    • (2010) Dev. Dyn , vol.240 , pp. 271-277
    • Jung, Y.1    Kissil, J.L.2    McCarty, J.H.3
  • 17
    • 67649432940 scopus 로고    scopus 로고
    • Feedback mechanism between blood vessels and astrocytes in retinal vascular development
    • Kubota, Y. and Suda, T. (2009). Feedback mechanism between blood vessels and astrocytes in retinal vascular development. Trends Cardiovasc. Med. 19, 38-43.
    • (2009) Trends Cardiovasc. Med , vol.19 , pp. 38-43
    • Kubota, Y.1    Suda, T.2
  • 19
    • 33646562542 scopus 로고    scopus 로고
    • The logic of TGFbeta signaling
    • Massague, J. and Gomis, R. R. (2006). The logic of TGFbeta signaling. FEBS Lett. 580, 2811-2820.
    • (2006) FEBS Lett , vol.580 , pp. 2811-2820
    • Massague, J.1    Gomis, R.R.2
  • 21
    • 13444249941 scopus 로고    scopus 로고
    • Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death
    • McCarty, J. H., Lacy-Hulbert, A., Charest, A., Bronson, R. T., Crowley, D., Housman, D., Savill, J., Roes, J. and Hynes, R. O. (2005). Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death. Development 132, 165-176.
    • (2005) Development , vol.132 , pp. 165-176
    • McCarty, J.H.1    Lacy-Hulbert, A.2    Charest, A.3    Bronson, R.T.4    Crowley, D.5    Housman, D.6    Savill, J.7    Roes, J.8    Hynes, R.O.9
  • 22
    • 0030609086 scopus 로고    scopus 로고
    • Expression of alphavbeta3 and alphavbeta8 integrins during oligodendrocyte precursor differentiation in the presence and absence of axons
    • Milner, R., Frost, E., Nishimura, S., Delcommenne, M., Streuli, C., Pytela, R. and Ffrench-Constant, C. (1997). Expression of alphavbeta3 and alphavbeta8 integrins during oligodendrocyte precursor differentiation in the presence and absence of axons. Glia 21, 350-360.
    • (1997) Glia , vol.21 , pp. 350-360
    • Milner, R.1    Frost, E.2    Nishimura, S.3    Delcommenne, M.4    Streuli, C.5    Pytela, R.6    Ffrench-Constant, C.7
  • 23
    • 69449106828 scopus 로고    scopus 로고
    • β8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain
    • Mobley, A. K., Tchaicha, J. H., Shin, J., Hossain, M. G. and McCarty, J. H. (2009). β8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain. J. Cell Sci. 122, 1842-1851.
    • (2009) J. Cell Sci , vol.122 , pp. 1842-1851
    • Mobley, A.K.1    Tchaicha, J.H.2    Shin, J.3    Hossain, M.G.4    McCarty, J.H.5
  • 24
    • 41949090936 scopus 로고    scopus 로고
    • TGFbeta1 and TGFbeta3 are partially redundant effectors in brain vascular morphogenesis
    • Mu, Z., Yang, Z., Yu, D., Zhao, Z. and Munger, J. S. (2008). TGFbeta1 and TGFbeta3 are partially redundant effectors in brain vascular morphogenesis. Mech. Dev. 125, 508-516.
    • (2008) Mech. Dev , vol.125 , pp. 508-516
    • Mu, Z.1    Yang, Z.2    Yu, D.3    Zhao, Z.4    Munger, J.S.5
  • 26
    • 0032571765 scopus 로고    scopus 로고
    • Synaptic and glial localization of the integrin alphavbeta8 in mouse and rat brain
    • Nishimura, S. L., Boylen, K. P., Einheber, S., Milner, T. A., Ramos, D. M. and Pytela, R. (1998). Synaptic and glial localization of the integrin alphavbeta8 in mouse and rat brain. Brain Res. 791, 271-282.
    • (1998) Brain Res , vol.791 , pp. 271-282
    • Nishimura, S.L.1    Boylen, K.P.2    Einheber, S.3    Milner, T.A.4    Ramos, D.M.5    Pytela, R.6
  • 28
    • 77955860340 scopus 로고    scopus 로고
    • Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice
    • Pitulescu, M. E., Schmidt, I., Benedito, R. and Adams, R. H. (2010). Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice. Nat. Protoc. 5, 1518-1534.
    • (2010) Nat. Protoc , vol.5 , pp. 1518-1534
    • Pitulescu, M.E.1    Schmidt, I.2    Benedito, R.3    Adams, R.H.4
  • 29
    • 27344444684 scopus 로고    scopus 로고
    • Vascular development of the brain requires beta8 integrin expression in the neuroepithelium
    • Proctor, J. M., Zang, K., Wang, D., Wang, R. and Reichardt, L. F. (2005). Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J. Neurosci. 25, 9940-9948.
    • (2005) J. Neurosci , vol.25 , pp. 9940-9948
    • Proctor, J.M.1    Zang, K.2    Wang, D.3    Wang, R.4    Reichardt, L.F.5
  • 30
    • 58149462229 scopus 로고    scopus 로고
    • The role of cell adhesion pathways in angiogenesis
    • Ramjaun, A. R. and Hodivala-Dilke, K. (2009). The role of cell adhesion pathways in angiogenesis. Int. J. Biochem. Cell Biol. 41, 521-530.
    • (2009) Int. J. Biochem. Cell Biol , vol.41 , pp. 521-530
    • Ramjaun, A.R.1    Hodivala-Dilke, K.2
  • 32
    • 0037108152 scopus 로고    scopus 로고
    • Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis
    • Ruhrberg, C., Gerhardt, H., Golding, M., Watson, R., Ioannidou, S., Fujisawa, H., Betsholtz, C. and Shima, D. T. (2002). Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev. 16, 2684-2698.
    • (2002) Genes Dev , vol.16 , pp. 2684-2698
    • Ruhrberg, C.1    Gerhardt, H.2    Golding, M.3    Watson, R.4    Ioannidou, S.5    Fujisawa, H.6    Betsholtz, C.7    Shima, D.T.8
  • 33
    • 77955619335 scopus 로고    scopus 로고
    • Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature
    • Scott, A., Powner, M. B., Gandhi, P., Clarkin, C., Gutmann, D. H., Johnson, R. S., Ferrara, N. and Fruttiger, M. (2010). Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature. PLoS One 5, e11863.
    • (2010) PLoS One , vol.e11863 , pp. 5
    • Scott, A.1    Powner, M.B.2    Gandhi, P.3    Clarkin, C.4    Gutmann, D.H.5    Johnson, R.S.6    Ferrara, N.7    Fruttiger, M.8
  • 37
    • 77955472749 scopus 로고    scopus 로고
    • A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis
    • Tchaicha, J. H., Mobley, A. K., Hossain, M. G., Aldape, K. D. and McCarty, J. H. (2010). A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis. Oncogene 29, 4460-4472.
    • (2010) Oncogene , vol.29 , pp. 4460-4472
    • Tchaicha, J.H.1    Mobley, A.K.2    Hossain, M.G.3    Aldape, K.D.4    McCarty, J.H.5
  • 38
    • 80054044019 scopus 로고    scopus 로고
    • Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by {beta}8 integrin
    • Tchaicha, J. H., Reyes, S. B., Shin, J., Hossain, M. G., Lang, F. F. and McCarty, J. H. (2011). Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by {beta}8 integrin. Cancer Res. 71, 6371-6381.
    • (2011) Cancer Res , vol.71 , pp. 6371-6381
    • Tchaicha, J.H.1    Reyes, S.B.2    Shin, J.3    Hossain, M.G.4    Lang, F.F.5    McCarty, J.H.6
  • 40
    • 0028989654 scopus 로고
    • Beta 8 integrins mediate interactions of chick sensory neurons with laminin-1, collagen IV, and fibronectin
    • Venstrom, K. and Reichardt, L. (1995). Beta 8 integrins mediate interactions of chick sensory neurons with laminin-1, collagen IV, and fibronectin. Mol. Biol. Cell 6, 419-431.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 419-431
    • Venstrom, K.1    Reichardt, L.2
  • 41
    • 64549113715 scopus 로고    scopus 로고
    • TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature
    • Walshe, T. E., Saint-Geniez, M., Maharaj, A. S., Sekiyama, E., Maldonado, A. E. and D'Amore, P. A. (2009). TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS One 4, e5149.
    • (2009) PLoS One , vol.4
    • Walshe, T.E.1    Saint-Geniez, M.2    Maharaj, A.S.3    Sekiyama, E.4    Maldonado, A.E.5    D'amore, P.A.6
  • 44
    • 61749097816 scopus 로고    scopus 로고
    • Tgf-beta superfamily signaling in embryonic development and homeostasis
    • Wu, M. Y. and Hill, C. S. (2009). Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev. Cell 16, 329-343.
    • (2009) Dev. Cell , vol.16 , pp. 329-343
    • Wu, M.Y.1    Hill, C.S.2
  • 45
    • 12144289950 scopus 로고    scopus 로고
    • Vascular development in the retina and inner ear: Control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair
    • Xu, Q., Wang, Y., Dabdoub, A., Smallwood, P. M., Williams, J., Woods, C., Kelley, M. W., Jiang, L., Tasman, W., Zhang, K. et al. (2004). Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 116, 883-895.
    • (2004) Cell , vol.116 , pp. 883-895
    • Xu, Q.1    Wang, Y.2    Dabdoub, A.3    Smallwood, P.M.4    Williams, J.5    Woods, C.6    Kelley, M.W.7    Jiang, L.8    Tasman, W.9    Zhang, K.10
  • 46
    • 33947494578 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor acts as an opponent of growth-stimulatory factors in retinal glial-endothelial cell interactions
    • Yafai, Y., Lange, J., Wiedemann, P., Reichenbach, A. and Eichler, W. (2007). Pigment epithelium-derived factor acts as an opponent of growth-stimulatory factors in retinal glial-endothelial cell interactions. Glia 55, 642-651.
    • (2007) Glia , vol.55 , pp. 642-651
    • Yafai, Y.1    Lange, J.2    Wiedemann, P.3    Reichenbach, A.4    Eichler, W.5
  • 47
    • 70349816655 scopus 로고    scopus 로고
    • Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization
    • Ye, X., Wang, Y., Cahill, H., Yu, M., Badea, T. C., Smallwood, P. M., Peachey, N. S. and Nathans, J. (2009). Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell 139, 285-298.
    • (2009) Cell , vol.139 , pp. 285-298
    • Ye, X.1    Wang, Y.2    Cahill, H.3    Yu, M.4    Badea, T.C.5    Smallwood, P.M.6    Peachey, N.S.7    Nathans, J.8
  • 48
    • 77957021581 scopus 로고    scopus 로고
    • Astrocyte heterogeneity: An underappreciated topic in neurobiology
    • Zhang, Y. and Barres, B. A. (2010). Astrocyte heterogeneity: an underappreciated topic in neurobiology. Curr. Opin. Neurobiol. 20, 588-594.
    • (2010) Curr. Opin. Neurobiol , vol.20 , pp. 588-594
    • Zhang, Y.1    Barres, B.A.2
  • 49
    • 0035984003 scopus 로고    scopus 로고
    • Beta8 integrins are required for vascular morphogenesis in mouse embryos
    • Zhu, J., Motejlek, K., Wang, D., Zang, K., Schmidt, A. and Reichardt, L. F. (2002). beta8 integrins are required for vascular morphogenesis in mouse embryos. Development 129, 2891-2903.
    • (2002) Development , vol.129 , pp. 2891-2903
    • Zhu, J.1    Motejlek, K.2    Wang, D.3    Zang, K.4    Schmidt, A.5    Reichardt, L.F.6


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