메뉴 건너뛰기




Volumn 36, Issue 3, 2013, Pages 513-521

Caspase induction and BCL2 inhibition in human adipose tissue

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CD11B ANTIGEN; COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 3; GLUCOSE TRANSPORTER 4; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 6; LEPTIN; LEUKOCYTE ANTIGEN; MESSENGER RNA; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE 1B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84874432639     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc12-0194     Document Type: Article
Times cited : (58)

References (42)
  • 1
    • 0025748673 scopus 로고
    • Metabolic implications of body fat distribution
    • Björntorp P. Metabolic implications of body fat distribution. Diabetes Care 1991; 14:1132-1143
    • (1991) Diabetes Care , vol.14 , pp. 1132-1143
    • Björntorp, P.1
  • 2
    • 28144442030 scopus 로고    scopus 로고
    • All obese individuals are not created equal: Insulin resistance is the major determinant of cardiovascular disease in overweight/obese individuals
    • Reaven G. All obese individuals are not created equal: insulin resistance is the major determinant of cardiovascular disease in overweight/obese individuals. Diab Vasc Dis Res 2005;2:105-112
    • (2005) Diab Vasc Dis Res , vol.2 , pp. 105-112
    • Reaven, G.1
  • 5
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Després JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006; 444:881-887
    • (2006) Nature , vol.444 , pp. 881-887
    • Després, J.P.1    Lemieux, I.2
  • 6
    • 77649171169 scopus 로고    scopus 로고
    • The distinction of metabolically 'healthy' from'unhealthy' obese individuals
    • Bluher M. The distinction of metabolically 'healthy' from'unhealthy' obese individuals. Curr Opin Lipidol 2010;21:38-43
    • (2010) Curr Opin Lipidol , vol.21 , pp. 38-43
    • Bluher, M.1
  • 7
    • 0036787485 scopus 로고    scopus 로고
    • Components of the 'metabolic syndrome' and incidence of type 2 diabetes
    • Hanson RL, Imperatore G, Bennett PH, Knowler WC. Components of the 'metabolic syndrome' and incidence of type 2 diabetes. Diabetes 2010;51:3120-3127
    • (2010) Diabetes , vol.51 , pp. 3120-3127
    • Hanson, R.L.1    Imperatore, G.2    Bennett, P.H.3    Knowler, W.C.4
  • 8
    • 53849143606 scopus 로고    scopus 로고
    • Adipose tissue expandability: The metabolic problems of obesity may arise from the inability to become more obese
    • Tan CY, Vidal-Puig A. Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese. Biochem Soc Trans 2008;36:935-940
    • (2008) Biochem Soc Trans , vol.36 , pp. 935-940
    • Tan, C.Y.1    Vidal-Puig, A.2
  • 9
    • 69249205739 scopus 로고    scopus 로고
    • Obesity, inflammation, and atherosclerosis
    • Rocha VZ, Libby P. Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol 2009; 6:399-409
    • (2009) Nat Rev Cardiol , vol.6 , pp. 399-409
    • Rocha, V.Z.1    Libby, P.2
  • 11
    • 0032575688 scopus 로고    scopus 로고
    • The bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 1998;281:1322-1326
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 12
    • 49049086338 scopus 로고    scopus 로고
    • Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhapo2l/trail)
    • Ashkenazi A, Holland P, Eckhardt SG. Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J Clin Oncol 2008;26: 3621-3630
    • (2008) J Clin Oncol , vol.26 , pp. 3621-3630
    • Ashkenazi, A.1    Holland, P.2    Eckhardt, S.G.3
  • 13
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997;326:1-16
    • (1997) Biochem J , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 14
    • 39449093070 scopus 로고    scopus 로고
    • Caspase activation cascades in apoptosis
    • Logue SE, Martin SJ. Caspase activation cascades in apoptosis. Biochem Soc Trans 2008;36:1-9
    • (2008) Biochem Soc Trans , vol.36 , pp. 1-9
    • Logue, S.E.1    Martin, S.J.2
  • 15
    • 1842555274 scopus 로고    scopus 로고
    • Subcellular targeting regulates the function of caspase-activated protein kinases in apoptosis
    • Jakobi R. Subcellular targeting regulates the function of caspase-activated protein kinases in apoptosis. Drug Resist Updat 2004;7:11-17
    • (2004) Drug Resist Updat , vol.7 , pp. 11-17
    • Jakobi, R.1
  • 17
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005; 46:2347-2355
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 18
    • 79958055441 scopus 로고    scopus 로고
    • An inflammatory micro-environment promotes human adipocyte apoptosis
    • Keuper M, Bluher M, Schön MR, et al. An inflammatory micro-environment promotes human adipocyte apoptosis. Mol Cell Endocrinol 2011;339:105-113
    • (2011) Mol Cell Endocrinol , vol.339 , pp. 105-113
    • Keuper, M.1    Bluher, M.2    Schön, M.R.3
  • 19
    • 33845668250 scopus 로고    scopus 로고
    • Clinical implications of adipose tissue remodelling: Adipogenesis and apoptosis
    • Sorisky A, Gagnon AM. Clinical implications of adipose tissue remodelling: adipogenesis and apoptosis. Canadian Journal of Diabetes 2002;26:232-240
    • (2002) Canadian Journal of Diabetes , vol.26 , pp. 232-240
    • Sorisky, A.1    Gagnon, A.M.2
  • 21
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol 2008;9:367-377
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 22
    • 79551584144 scopus 로고    scopus 로고
    • Hyperglycemia activates caspase-1 and txnip-mediated il-1beta transcription in human adipose tissue
    • Koenen TB, Stienstra R, van Tits LJ, et al. Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue. Diabetes 2011; 60:517-524
    • (2011) Diabetes , vol.60 , pp. 517-524
    • Koenen, T.B.1    Stienstra, R.2    Van Tits, L.J.3
  • 24
    • 77449083262 scopus 로고    scopus 로고
    • Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis
    • Alkhouri N, Gornicka A, Berk MP, et al. Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis. J Biol Chem 2010;285:3428-3438
    • (2010) J Biol Chem , vol.285 , pp. 3428-3438
    • Alkhouri, N.1    Gornicka, A.2    Berk, M.P.3
  • 25
    • 0033213631 scopus 로고    scopus 로고
    • Ppar g is required for the differentiation of adipose tissue in vivo and in vitro
    • Rosen EDP, Sarraf P, Troy AE, et al. PPAR g is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 1999;4:611-617
    • (1999) Mol Cell , vol.4 , pp. 611-617
    • Rosen, E.D.P.1    Sarraf, P.2    Troy, A.E.3
  • 26
    • 67650539080 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes
    • Guilherme A, Tesz GJ, Guntur KV, Czech MP. Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes. J Biol Chem 2009;284: 17082-17091
    • (2009) J Biol Chem , vol.284 , pp. 17082-17091
    • Guilherme, A.1    Tesz, G.J.2    Guntur, K.V.3    Czech, M.P.4
  • 27
    • 39449104855 scopus 로고    scopus 로고
    • Guggulsterone inhibits adipocyte differentiation and induces apoptosis in 3t3-l1 cells
    • Yang JY, Della-Fera MA, Baile CA. Guggulsterone inhibits adipocyte differentiation and induces apoptosis in 3T3-L1 cells. Obesity (Silver Spring) 2008;16:16-22
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 16-22
    • Yang, J.Y.1    Della-Fera, M.A.2    Baile, C.A.3
  • 28
    • 44849132591 scopus 로고    scopus 로고
    • Dynamics of fat cell turnover in humans
    • Spalding KL, Arner E, Westermark PO, et al. Dynamics of fat cell turnover in humans. Nature 2008;453:783-787
    • (2008) Nature , vol.453 , pp. 783-787
    • Spalding, K.L.1    Arner, E.2    Westermark, P.O.3
  • 29
    • 0032482988 scopus 로고    scopus 로고
    • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of bcl-2 expression
    • Shimabukuro M, Wang MY, Zhou YT, Newgard CB, Unger RH. Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. Proc Natl Acad Sci USA 1998; 95:9558-9561
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9558-9561
    • Shimabukuro, M.1    Wang, M.Y.2    Zhou, Y.T.3    Newgard, C.B.4    Unger, R.H.5
  • 30
    • 0037631831 scopus 로고    scopus 로고
    • Insulin resistance and chronic cardiovascular inflammatory syndrome
    • Fern-andez-Real JM, Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003; 24:278-301
    • (2003) Endocr Rev , vol.24 , pp. 278-301
    • Fern-andez-Real, J.M.1    Ricart, W.2
  • 31
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007;117:175-184
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 32
    • 0030779809 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces apoptosis of human adipose cells
    • Prins JB, Niesler CU, Winterford CM, et al. Tumor necrosis factor-alpha induces apoptosis of human adipose cells. Diabetes 1997;46:1939-1944
    • (1997) Diabetes , vol.46 , pp. 1939-1944
    • Prins, J.B.1    Niesler, C.U.2    Winterford, C.M.3
  • 33
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995;95: 2409-2415
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 34
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 35
    • 0035403205 scopus 로고    scopus 로고
    • Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion
    • Vozarova B, Weyer C, Hanson K, Tataranni PA, Bogardus C, Pratley RE. Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion. Obes Res 2001;9:414-417
    • (2001) Obes Res , vol.9 , pp. 414-417
    • Vozarova, B.1    Weyer, C.2    Hanson, K.3    Tataranni, P.A.4    Bogardus, C.5    Pratley, R.E.6
  • 36
    • 0033678516 scopus 로고    scopus 로고
    • Elevated levels of interleukin 6 are reduced in serumand subcutaneous adipose tissue of obese women after weight loss
    • Bastard JP, Jardel C, Bruckert E, et al. Elevated levels of interleukin 6 are reduced in serumand subcutaneous adipose tissue of obese women after weight loss. J Clin Endocrinol Metab 2000;85:3338-3342
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3338-3342
    • Bastard, J.P.1    Jardel, C.2    Bruckert, E.3
  • 37
    • 0036136567 scopus 로고    scopus 로고
    • Obesity modulates the expression of haptoglobin in the white adipose tissue via tnfalpha
    • Chiellini C, Bertacca A, Novelli SE, et al. Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha. J Cell Physiol 2002;190: 251-258
    • (2002) J Cell Physiol , vol.190 , pp. 251-258
    • Chiellini, C.1    Bertacca, A.2    Novelli, S.E.3
  • 38
    • 0027050648 scopus 로고
    • Wildtype p53 binds to the tata-binding protein and represses transcription
    • Seto E, Usheva A, Zambetti GP, et al.Wildtype p53 binds to the TATA-binding protein and represses transcription. Proc Natl Acad Sci USA 1992;89:12028-12032
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 12028-12032
    • Seto, E.1    Usheva, A.2    Zambetti, G.P.3
  • 39
    • 0027318117 scopus 로고
    • Specific repression of tata-mediated but not initiator-mediated transcription by wild-type p53
    • Mack DH, Vartikar J, Pipas JM, Laimins LA. Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53. Nature 1993;363:281-283
    • (1993) Nature , vol.363 , pp. 281-283
    • Mack, D.H.1    Vartikar, J.2    Pipas, J.M.3    Laimins, L.A.4
  • 41
    • 69949150673 scopus 로고    scopus 로고
    • A crucial role for adipose tissue p53 in the regulation of insulin resistance
    • Minamino T, Orimo M, Shimizu I, et al. A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med 2009;15:1082-1087
    • (2009) Nat Med , vol.15 , pp. 1082-1087
    • Minamino, T.1    Orimo, M.2    Shimizu, I.3
  • 42
    • 51049095727 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor, p21waf1/cip1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance
    • Inoue N, Yahagi N, Yamamoto T, et al. Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance. J Biol Chem 2008;283:21220-21229
    • (2008) J Biol Chem , vol.283 , pp. 21220-21229
    • Inoue, N.1    Yahagi, N.2    Yamamoto, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.