Altered nano/micro-order elasticity of pulmonary artery smooth muscle cells of patients with idiopathic pulmonary arterial hypertension

International Journal of Cardiology

Volumn 140, Issue 1, 2010, Pages 102-107

  Nakamura, Kazufumi ^a,b   Shimizu, Juichiro ^b,c   Kataoka, Noriyuki ^d   Hashimoto, Katsushi ^a   Ikeda, Tetsuya ^a   Fujio, Hideki ^a   Ohta Ogo, Keiko ^a   Ogawa, Aiko ^a   Miura, Aya ^a   Mohri, Satoshi ^c   Nagase, Satoshi ^a   Morita, Hiroshi ^a   Kusano, Kengo Fukushima ^a   Date, Hiroshi ^c   Matsubara, Hiromi ^e   Mochizuki, Seiichi ^d   Hashimoto, Ken ^d   Kajiya, Fumihiko ^c,d   Ohe, Tohru ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d KAWASAKI MEDICAL SCHOOL   (Japan)

^e NATIONAL HOSPITAL ORGANIZATION OKAYAMA MEDICAL CENTER   (Japan)

Author keywords

Atomic force microscope; Nitric oxide; Pulmonary hypertension; Smooth muscle cell; Vasodilator

Indexed keywords

NITRIC OXIDE;

ADOLESCENT; ADULT; ARTERY MUSCLE; ARTICLE; ATOMIC FORCE MICROSCOPY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ELASTICITY; FEMALE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; SCHOOL CHILD; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; VASODILATATION;

ADOLESCENT; ADULT; CELLS, CULTURED; CHILD; ELASTICITY; FEMALE; FREE RADICAL SCAVENGERS; HUMANS; HYPERTENSION, PULMONARY; MALE; MICROSCOPY, ATOMIC FORCE; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; NANOSTRUCTURES; NITRIC OXIDE; VASODILATOR AGENTS; YOUNG ADULT;

EID: 77949488674     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2008.11.022     Document Type: Article

References (32)

1. Rich S., Dantzker D.R., Ayres S.M., et al. Primary pulmonary hypertension. A national prospective study. Ann Intern Med 107 (1987) 216-223
2. Lane K.B., Machado R.D., Pauciulo M.W., et al. Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium. Nat Genet 26 (2000) 81-84
3. Deng Z., Morse J.H., Slager S.L., et al. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet 67 (2000) 737-744
4. Archer S., and Rich S. Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation 102 (2000) 2781-2791
5. Farber H.W., and Loscalzo J. Prothrombotic mechanisms in primary pulmonary hypertension. J Lab Clin Med 134 (1999) 561-566
6. Christman B.W., McPherson C.D., Newman J.H., et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med 327 (1992) 70-75
7. Stewart D.J., Levy R.D., Cernacek P., and Langleben D. Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?. Ann Intern Med 114 (1991) 464-469
8. Rubens C., Ewert R., Halank M., et al. Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest 120 (2001) 1562-1569
9. Giaid A., and Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med 333 (1995) 214-221
10. Hashimoto K., Nakamura K., Fujio H., et al. Epoprostenol therapy decreases elevated circulating levels of monocyte chemoattractant protein-1 in patients with primary pulmonary hypertension. Circ J 68 (2004) 227-231
11. Ogawa A., Nakamura K., Matsubara H., et al. Prednisolone inhibits proliferation of cultured pulmonary artery smooth muscle cells of patients with idiopathic pulmonary arterial hypertension. Circulation 112 (2005) 1806-1812
12. Cool C.D., Rai P.R., Yeager M.E., et al. Expression of human herpesvirus 8 in primary pulmonary hypertension. N Engl J Med 349 (2003) 1113-1122
13. Yuan X.J., Tod M.L., Rubin L.J., and Blaustein M.P. NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels. Proc Natl Acad Sci U S A 93 (1996) 10489-10494
14. Yuan J.X., Aldinger A.M., Juhaszova M., et al. Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension. Circulation 98 (1998) 1400-1406
15. Kaneko F.T., Arroliga A.C., Dweik R.A., et al. Biochemical reaction products of nitric oxide as quantitative markers of primary pulmonary hypertension. Am J Respir Crit Care Med 158 (1998) 917-923
16. A-Hassan E., Heinz W.F., Antonik M.D., et al. Relative microelastic mapping of living cells by atomic force microscopy. Biophys J 74 (1998) 1564-1578
17. Alonso J.L., and Goldmann W.H. Feeling the forces: atomic force microscopy in cell biology. Life Sci 72 (2003) 2553-2560
18. Kataoka N., Iwaki K., Hashimoto K., et al. Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion. Proc Natl Acad Sci U S A 99 (2002) 15638-15643
19. Sato M., Nagayama K., Kataoka N., Sasaki M., and Hane K. Local mechanical properties measured by atomic force microscopy for cultured bovine endothelial cells exposed to shear stress. J Biomech 33 (2000) 127-135
20. Date H., Aoe M., Nagahiro I., et al. Living-donor lobar lung transplantation for various lung diseases. J Thorac Cardiovasc Surg 126 (2003) 476-481
21. Date H., Kusano K.F., Matsubara H., et al. Living-donor lobar lung transplantation for pulmonary arterial hypertension after failure of epoprostenol therapy. J Am Coll Cardiol 50 (2007) 523-527
22. Takeda M., Otsuka F., Nakamura K., et al. Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action. Endocrinology 145 (2004) 4344-4354
23. Kouchi H., Nakamura K., Fushimi K., et al. Manumycin A, inhibitor of ras farnesyltransferase, inhibits proliferation and migration of rat vascular smooth muscle cells. Biochem Biophys Res Commun 264 (1999) 915-920
24. Fujio H., Nakamura K., Matsubara H., et al. Carvedilol inhibits proliferation of cultured pulmonary artery smooth muscle cells of patients with idiopathic pulmonary arterial hypertension. J Cardiovasc Pharmacol 47 (2006) 250-255
25. Thyberg J. Differentiated properties and proliferation of arterial smooth muscle cells in culture. Int Rev Cyt 169 (1996) 183-265
26. Chamley-Campbell J., Campbell G.R., and Ross R. The smooth muscle cell in culture. Physiol Rev 59 (1979) 1-61
27. Berra-Romani R., Mazzocco-Spezzia A., Pulina M.V., and Golovina V.A. Ca2+ handling is altered when arterial myocytes progress from a contractile to a proliferative phenotype in culture. Am J Physiol 295 (2008) C779-C790
28. Nakamura K., Kusano K., Nakamura Y., et al. Carvedilol decreases elevated oxidative stress in human failing myocardium. Circulation 105 (2002) 2867-2871
29. Radmacher M., Fritz M., Kacher C.M., Cleveland J.P., and Hansma P.K. Measuring the viscoelastic properties of human platelets with the atomic force microscope. Biophys J 70 (1996) 556-567
30. Neishi Y., Mochizuki S., Miyasaka T., et al. Evaluation of bioavailability of nitric oxide in coronary circulation by direct measurement of plasma nitric oxide concentration. Proc Natl Acad Sci U S A 102 (2005) 11456-11461
31. Lee K.M., Tsai K.Y., Wang N., and Ingber D.E. Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. Am J Physiol 274 (1998) H76-H82
32. Coats A.J. Ethical authorship and publishing. Int J Cardiol 131 (2009) 149-150