Worse prognosis of KRAS c.35 G > A mutant metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx)

BMC Medicine

Volumn 11, Issue 1, 2013, Pages

  Bruera, Gemma ^a   Cannita, Katia ^a   Di Giacomo, Daniela ^a   Lamy, Aude ^b   Frébourg, Thierry ^c   Sabourin, Jean Christophe ^b   Tosi, Mario ^c   Alesse, Edoardo ^a   Ficorella, Corrado ^a   Ricevuto, Enrico ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b ROUEN UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE ROUEN   (France)

Author keywords

FIr B FOx; Kras c.35 G > A mutation; KRAS mutation; Metastatic colorectal cancer; Triplet chemotherapy plus bevacizumab

Indexed keywords

ALANINE; B RAF KINASE; BEVACIZUMAB; FLUOROURACIL; GLYCINE; IRINOTECAN; K RAS PROTEIN; OXALIPLATIN; PHENYLALANINE; VALINE;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER SCREENING; CODON; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; GENE MUTATION; HUMAN; LIVER; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTATIC COLORECTAL CANCER; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; PREVALENCE; PROGRESSION FREE SURVIVAL; RETROSPECTIVE STUDY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE; WILD TYPE;

AGED; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; COLORECTAL NEOPLASMS; DRUG THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84874405681     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-11-59     Document Type: Article

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