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Volumn 10, Issue , 2012, Pages

Prognostic value of KRAS genotype in metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx) according to extension of metastatic disease

Author keywords

Disease Extension; Intensive Regimen; KRAS mutations; Metastatic Colorectal Cancer; Triplet Chemotherapy Plus Bevacizumab

Indexed keywords

BEVACIZUMAB; FLUOROURACIL; IRINOTECAN; K RAS PROTEIN; OXALIPLATIN;

EID: 84868501969     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-10-135     Document Type: Article
Times cited : (21)

References (37)
  • 1
    • 79955845350 scopus 로고    scopus 로고
    • Intensive chemotherapy of metastatic colorectal cancer: weighing between safety and clinical efficacy. Evaluation of Masi G, Loupakis F, Salvatore L, et al. Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial. Lancet Oncol 2010;11:845-52
    • Bruera G, Ricevuto E. Intensive chemotherapy of metastatic colorectal cancer: weighing between safety and clinical efficacy. Evaluation of Masi G, Loupakis F, Salvatore L, et al. Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial. Lancet Oncol 2010;11:845-52. Exp Opin Biol Ther 2011, 11:821-824.
    • (2011) Exp Opin Biol Ther , vol.11 , pp. 821-824
    • Bruera, G.1    Ricevuto, E.2
  • 4
    • 77957916099 scopus 로고    scopus 로고
    • "Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study
    • 10.1186/1471-2407-10-67, 2846883, 20181281
    • Bruera G, Santomaggio A, Cannita K, Lanfiuti Baldi P, Tudini M, De Galitiis F, Mancini M, Marchetti P, Antonucci A, Ficorella C, Ricevuto E. "Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study. BMC Cancer 2010, 10:67. 10.1186/1471-2407-10-67, 2846883, 20181281.
    • (2010) BMC Cancer , vol.10 , pp. 67
    • Bruera, G.1    Santomaggio, A.2    Cannita, K.3    Lanfiuti Baldi, P.4    Tudini, M.5    De Galitiis, F.6    Mancini, M.7    Marchetti, P.8    Antonucci, A.9    Ficorella, C.10    Ricevuto, E.11
  • 5
    • 78149469673 scopus 로고    scopus 로고
    • Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadiuvant chemotherapy in colorectal liver metastases: POCHER trial
    • 10.1038/sj.bjc.6605940, 2990583, 20959822
    • Garufi C, Torsello A, Tumolo S, Ettorre GM, Zeuli M, Campanella C, Vennarecci G, Mottolese M, Sperduti I, Cognetti F. Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadiuvant chemotherapy in colorectal liver metastases: POCHER trial. Br J Cancer 2010, 103:1542-1547. 10.1038/sj.bjc.6605940, 2990583, 20959822.
    • (2010) Br J Cancer , vol.103 , pp. 1542-1547
    • Garufi, C.1    Torsello, A.2    Tumolo, S.3    Ettorre, G.M.4    Zeuli, M.5    Campanella, C.6    Vennarecci, G.7    Mottolese, M.8    Sperduti, I.9    Cognetti, F.10
  • 6
  • 7
    • 0035256698 scopus 로고    scopus 로고
    • Untangling the ErbB signalling network
    • 10.1038/35052073, 11252954
    • Yarden Y, Sliwkowsky MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001, 2:127-137. 10.1038/35052073, 11252954.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 127-137
    • Yarden, Y.1    Sliwkowsky, M.X.2
  • 8
    • 33749316418 scopus 로고    scopus 로고
    • The epidermal growth factor receptor pathway: a model for targeted therapy
    • 10.1158/1078-0432.CCR-05-1554, 17000658
    • Scaltriti M, Baselga J. The epidermal growth factor receptor pathway: a model for targeted therapy. Clin Cancer Res 2006, 12:5268-5272. 10.1158/1078-0432.CCR-05-1554, 17000658.
    • (2006) Clin Cancer Res , vol.12 , pp. 5268-5272
    • Scaltriti, M.1    Baselga, J.2
  • 11
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: a review
    • Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989, 49:4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 14
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive ras in developmental disorders and cancer
    • 10.1038/nrc2109, 17384584
    • Schubbert S, Shannon K, Bollag G. Hyperactive ras in developmental disorders and cancer. Nat Rev Cancer 2007, 7:295-308. 10.1038/nrc2109, 17384584.
    • (2007) Nat Rev Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 16
    • 0038648571 scopus 로고    scopus 로고
    • Molecular changes in the Ki-ras and APC genes in primary colorectal carcinoma and synchorous metastases compared with the findings in accompanying adenomas
    • 10.1136/mp.56.3.137, 1187308, 12782759
    • Zauber P, Sabbath-Solitare M, Marotta SP, Bishop DT. Molecular changes in the Ki-ras and APC genes in primary colorectal carcinoma and synchorous metastases compared with the findings in accompanying adenomas. Mol Pathol 2003, 56:137-140. 10.1136/mp.56.3.137, 1187308, 12782759.
    • (2003) Mol Pathol , vol.56 , pp. 137-140
    • Zauber, P.1    Sabbath-Solitare, M.2    Marotta, S.P.3    Bishop, D.T.4
  • 19
    • 8444220804 scopus 로고    scopus 로고
    • Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of K-ras and p53 mutations
    • 10.1016/j.bbrc.2004.10.111, 15541358
    • Albanese I, Scibetta AG, Migliavacca M, Russo A, Bazan V, Tomasino RM, Colomba P, Tagliavia M, La Farina M. Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of K-ras and p53 mutations. Biochem Biophys Res Commun 2004, 325:784-791. 10.1016/j.bbrc.2004.10.111, 15541358.
    • (2004) Biochem Biophys Res Commun , vol.325 , pp. 784-791
    • Albanese, I.1    Scibetta, A.G.2    Migliavacca, M.3    Russo, A.4    Bazan, V.5    Tomasino, R.M.6    Colomba, P.7    Tagliavia, M.8    La Farina, M.9
  • 20
    • 0025889018 scopus 로고
    • Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver
    • 10.1002/ijc.2910490613, 1959991
    • Oudejans JJ, Slebos RJ, Zoetmulder FA, Mooi WJ, Rodenhuis S. Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver. Int J Cancer 1991, 49:875-879. 10.1002/ijc.2910490613, 1959991.
    • (1991) Int J Cancer , vol.49 , pp. 875-879
    • Oudejans, J.J.1    Slebos, R.J.2    Zoetmulder, F.A.3    Mooi, W.J.4    Rodenhuis, S.5
  • 21
    • 61449202998 scopus 로고    scopus 로고
    • The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer
    • Hurwitz HI, Yi J, Ince W, Novotny WF, Rosen O. The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer. Oncologist 2009, 14:22-28.
    • (2009) Oncologist , vol.14 , pp. 22-28
    • Hurwitz, H.I.1    Yi, J.2    Ince, W.3    Novotny, W.F.4    Rosen, O.5
  • 28
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • 10.1093/jnci/92.3.205, 10655437
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Glabbeke MV, van Oosterom AT, Christian MC, Gwyther SG. New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000, 92:205-216. 10.1093/jnci/92.3.205, 10655437.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6    Verweij, J.7    Glabbeke, M.V.8    van Oosterom, A.T.9    Christian, M.C.10    Gwyther, S.G.11
  • 29
    • 33845382806 scopus 로고
    • Nonparametric estimation of incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation of incomplete observations. J Am Stat Assoc 1958, 53:457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 30
    • 0000957062 scopus 로고
    • Asymptomatically efficient rank invariant test procedures
    • Peto R, Peto J. Asymptomatically efficient rank invariant test procedures. J R Stat Soc A 1972, 135:185-206.
    • (1972) J R Stat Soc A , vol.135 , pp. 185-206
    • Peto, R.1    Peto, J.2
  • 34
    • 79956310674 scopus 로고    scopus 로고
    • Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study
    • 10.1093/annonc/mdq632, 21228335
    • Bokemeyer C, Bondarenko I, Hartmann JT, de Braud F, Schuch G, Zubel A, Celik I, Schlichting M, Koralewski P. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 2011, 22:1535-1546. 10.1093/annonc/mdq632, 21228335.
    • (2011) Ann Oncol , vol.22 , pp. 1535-1546
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3    de Braud, F.4    Schuch, G.5    Zubel, A.6    Celik, I.7    Schlichting, M.8    Koralewski, P.9
  • 37
    • 0034548712 scopus 로고    scopus 로고
    • K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression
    • Guerrero S, Casanova I, Farrè L, Mazo A, Capellà G, Mangues R. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression. Cancer Res 2000, 60:6750-6756.
    • (2000) Cancer Res , vol.60 , pp. 6750-6756
    • Guerrero, S.1    Casanova, I.2    Farrè, L.3    Mazo, A.4    Capellà, G.5    Mangues, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.