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Volumn 40, Issue 1, 2013, Pages 2-9

Biomarker blood tests for diagnosis and management of mental disorders: Focus on schizophrenia;Testes sanguíneos de biomarcadores para diagnóstico e tratamento de desordens mentais: Foco em esquizofrenia

Author keywords

Biomarkers; Diagnosis; Psychiatric disorders; Regulatory authorities; Schizophrenia

Indexed keywords

BIOLOGICAL MARKER;

EID: 84874388240     PISSN: 01016083     EISSN: 1806938X     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (81)
  • 1
    • 0029780768 scopus 로고    scopus 로고
    • A participant's observations: Preparing DSM-IV
    • Schaffer D. A participant's observations: preparing DSM-IV. Can J Psychiatry. 1996;41:325-9.
    • (1996) Can J Psychiatry. , vol.41 , pp. 325-329
    • Schaffer, D.1
  • 2
    • 33645463409 scopus 로고    scopus 로고
    • Funding for accelerating drug development initiative critical
    • Ovens J. Funding for accelerating drug development initiative critical. Nat Rev Drug Discov. 2006;5:271.
    • (2006) Nat Rev Drug Discov. , vol.5 , pp. 271
    • Ovens, J.1
  • 3
    • 34250754648 scopus 로고    scopus 로고
    • Critical Path is on the road forward; FDA reports industry activity is high
    • Marson B. "Critical Path" is on the road forward; FDA reports industry activity is high. The Pink Sheet. 2007;69:29.
    • (2007) The Pink Sheet. , vol.69 , pp. 29
    • Marson, B.1
  • 4
    • 34347330024 scopus 로고    scopus 로고
    • Implementing the U.S. FDA guidance on pharmacogenomic data submissions
    • Goodsaid F, Frueh FW. Implementing the U.S. FDA guidance on pharmacogenomic data submissions. Environ Mol Mutagen. 2007;48:354-8.
    • (2007) Environ Mol Mutagen. , vol.48 , pp. 354-358
    • Goodsaid, F.1    Frueh, F.W.2
  • 5
    • 77955207800 scopus 로고    scopus 로고
    • Validation of a blood-based laboratory test to aid in the confirmation of a diagnosis of schizophrenia
    • Schwarz E, Izmailov R, Spain M, Barnes A, Mapes JP, Guest PC, et al. Validation of a blood-based laboratory test to aid in the confirmation of a diagnosis of schizophrenia. Biomark Insights. 2010;5:39-47.
    • (2010) Biomark Insights. , vol.5 , pp. 39-47
    • Schwarz, E.1    Izmailov, R.2    Spain, M.3    Barnes, A.4    Mapes, J.P.5    Guest, P.C.6
  • 6
    • 0016759052 scopus 로고
    • Heterogeneity of schizophrenia
    • Tsuang MT. Heterogeneity of schizophrenia. Biol Psychiatry. 1975;10:465-74.
    • (1975) Biol Psychiatry. , vol.10 , pp. 465-474
    • Tsuang, M.T.1
  • 8
    • 0030345298 scopus 로고    scopus 로고
    • Models of scientific progress and the role of theory in taxonomy development: A case study of the DSM
    • Follette WC, Houts AC. Models of scientific progress and the role of theory in taxonomy development: a case study of the DSM. J Consult Clin Psychol. 1996;64:1120-32.
    • (1996) J Consult Clin Psychol. , vol.64 , pp. 1120-1132
    • Follette, W.C.1    Houts, A.C.2
  • 9
    • 77954792580 scopus 로고    scopus 로고
    • Misdiagnosing normality: Psychiatry's failure to address the problem of false positive diagnoses of mental disorder in a changing professional environment
    • Wakefield JC. Misdiagnosing normality: psychiatry's failure to address the problem of false positive diagnoses of mental disorder in a changing professional environment. J Ment Health. 2010;19:337-51.
    • (2010) J Ment Health. , vol.19 , pp. 337-351
    • Wakefield, J.C.1
  • 11
    • 67650468147 scopus 로고    scopus 로고
    • The diagnoses of schizophrenia, schizoaffective disorder, bipolar disorder and unipolar depression: Interrater reliability and congruence between DSM-IV and ICD-10
    • Cheniaux E, Landeira-Fernandez J, Versiani M. The diagnoses of schizophrenia, schizoaffective disorder, bipolar disorder and unipolar depression: interrater reliability and congruence between DSM-IV and ICD-10. Psychopathology. 2009;42:293-8.
    • (2009) Psychopathology. , vol.42 , pp. 293-298
    • Cheniaux, E.1    Landeira-Fernandez, J.2    Versiani, M.3
  • 13
    • 78349257431 scopus 로고    scopus 로고
    • Psychotic-like experiences, appraisals, and trauma
    • Lovatt A, Mason O, Brett C, Peters E. Psychotic-like experiences, appraisals, and trauma. J Nerv Ment Dis. 2010;198:813-9.
    • (2010) J Nerv Ment Dis. , vol.198 , pp. 813-819
    • Lovatt, A.1    Mason, O.2    Brett, C.3    Peters, E.4
  • 15
    • 0014702024 scopus 로고
    • Establishment of diagnostic validity in psychiatric illness: Its application to schizophrenia
    • Robins E, Guze SB. Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. Am J Psychiatry. 1970;126:983-7.
    • (1970) Am J Psychiatry. , vol.126 , pp. 983-987
    • Robins, E.1    Guze, S.B.2
  • 17
    • 41549156607 scopus 로고    scopus 로고
    • Incidence and diagnostic stability of ICD-10 acute and transient psychotic disorders
    • Castagnini A, Bertelsen A, Berrios GE. Incidence and diagnostic stability of ICD-10 acute and transient psychotic disorders. Compr Psychiatry. 2008;49(3):255-61.
    • (2008) Compr Psychiatry. , vol.49 , Issue.3 , pp. 255-261
    • Castagnini, A.1    Bertelsen, A.2    Berrios, G.E.3
  • 20
    • 0026692976 scopus 로고
    • Are we overestimating the genetic contribution to schizophrenia?
    • Torrey EF. Are we overestimating the genetic contribution to schizophrenia? Schizophr Bull. 1992;18:159-70.
    • (1992) Schizophr Bull. , vol.18 , pp. 159-170
    • Torrey, E.F.1
  • 21
    • 0026729152 scopus 로고
    • When assessing twin concordance, use the probandwise not the pairwise rate
    • McGue M. When assessing twin concordance, use the probandwise not the pairwise rate. Schizophr Bull. 1992;18:171-6.
    • (1992) Schizophr Bull. , vol.18 , pp. 171-176
    • McGue, M.1
  • 22
    • 0033956237 scopus 로고    scopus 로고
    • Schizophrenia: Genes and environment
    • Tsuang M. Schizophrenia: genes and environment. Biol Psychiatry. 2000;47:210-20.
    • (2000) Biol Psychiatry. , vol.47 , pp. 210-220
    • Tsuang, M.1
  • 23
    • 0033400756 scopus 로고    scopus 로고
    • Nutrition and neurodevelopment: Mechanisms of developmental dysfunction and disease in later life
    • Dauncey MJ, Bicknell RJ. Nutrition and neurodevelopment: mechanisms of developmental dysfunction and disease in later life. Nutr Res Rev. 1999;12:231-53.
    • (1999) Nutr Res Rev. , vol.12 , pp. 231-253
    • Dauncey, M.J.1    Bicknell, R.J.2
  • 24
    • 70349157245 scopus 로고    scopus 로고
    • Fetal origins of mental health: Evidence and mechanisms
    • Schlotz W, Phillips DI. Fetal origins of mental health: evidence and mechanisms. Brain Behav Immun. 2009;23:905-16.
    • (2009) Brain Behav Immun. , vol.23 , pp. 905-916
    • Schlotz, W.1    Phillips, D.I.2
  • 25
    • 0036297593 scopus 로고    scopus 로고
    • Glucocorticoid hormones and early brain development in schizophrenia
    • Koenig JI, Kirkpatrick B, Lee P. Glucocorticoid hormones and early brain development in schizophrenia. Neuropsychopharmacology. 2002;27:309-18.
    • (2002) Neuropsychopharmacology. , vol.27 , pp. 309-318
    • Koenig, J.I.1    Kirkpatrick, B.2    Lee, P.3
  • 26
    • 0037317444 scopus 로고    scopus 로고
    • Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia
    • Ryan MC, Collins P, Thakore JH. Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia. Am J Psychiatry. 2003;160:284-9.
    • (2003) Am J Psychiatry. , vol.160 , pp. 284-289
    • Ryan, M.C.1    Collins, P.2    Thakore, J.H.3
  • 27
    • 34247626414 scopus 로고    scopus 로고
    • Impaired glucose tolerance in first-episode drug-naive patients with schizophrenia
    • 481-445
    • Spelman LM, Walsh PI, Sharifi N, Collins P, Thakore JH. Impaired glucose tolerance in first-episode drug-naive patients with schizophrenia. Diabet Med. 2007;24:481-45.
    • (2007) Diabet Med. , vol.24
    • Spelman, L.M.1    Walsh, P.I.2    Sharifi, N.3    Collins, P.4    Thakore, J.H.5
  • 28
    • 75649138748 scopus 로고    scopus 로고
    • Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naive schizophrenia patients
    • Guest PC, Wang L, Harris LW, Burling K, Levin Y, Ernst A, et al. Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naive schizophrenia patients. Mol Psychiatry. 2010;15:118-9.
    • (2010) Mol Psychiatry. , vol.15 , pp. 118-119
    • Guest, P.C.1    Wang, L.2    Harris, L.W.3    Burling, K.4    Levin, Y.5    Ernst, A.6
  • 30
    • 84857548498 scopus 로고    scopus 로고
    • Impaired neuroendocrine and immune response to acute stress in medication-naive patients with a first episode of psychosis
    • Van Venrooij JA, Fluitman SB, Lijmer JG, Kavelaars A, Heijnen CJ, Westenberg HG, et al. Impaired neuroendocrine and immune response to acute stress in medication-naive patients with a first episode of psychosis. Schizophr Bull. 2012;38(2):272-9.
    • (2012) Schizophr Bull. , vol.38 , Issue.2 , pp. 272-279
    • van Venrooij, J.A.1    Fluitman, S.B.2    Lijmer, J.G.3    Kavelaars, A.4    Heijnen, C.J.5    Westenberg, H.G.6
  • 31
    • 84869170166 scopus 로고    scopus 로고
    • Identification of a blood-based biological signature in subjects with psychiatric disorders prior to clinical manifestation
    • (in press)
    • Schwarz E, Guest PC, Rahmoune H, Martins-de-Souza D, Niebuhr DW, Weber NS, et al. Identification of a blood-based biological signature in subjects with psychiatric disorders prior to clinical manifestation. World J Biol Psychiatry. 2011. (in press)
    • (2011) World J Biol Psychiatry
    • Schwarz, E.1    Guest, P.C.2    Rahmoune, H.3    Martins-de-Souza, D.4    Niebuhr, D.W.5    Weber, N.S.6
  • 32
    • 34447249064 scopus 로고    scopus 로고
    • Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Preliminary results
    • Agius M, Shah S, Ramkisson R, Murphy S, Zaman R. Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Preliminary results. Psychiatr Danub. 2007;19:10-9.
    • (2007) Psychiatr Danub. , vol.19 , pp. 10-19
    • Agius, M.1    Shah, S.2    Ramkisson, R.3    Murphy, S.4    Zaman, R.5
  • 33
    • 46749129769 scopus 로고    scopus 로고
    • Early detection and intervention of psychosis. A review
    • Salokangas RK, McGlashan TH. Early detection and intervention of psychosis. A review. Nord J Psychiatry. 2008;62:92-105.
    • (2008) Nord J Psychiatry. , vol.62 , pp. 92-105
    • Salokangas, R.K.1    McGlashan, T.H.2
  • 34
    • 78649461099 scopus 로고    scopus 로고
    • Early psychosis intervention
    • Yap HL. Early psychosis intervention. Singapore Med J. 2010;51;689-93.
    • (2010) Singapore Med J. , vol.51 , pp. 689-693
    • Yap, H.L.1
  • 35
    • 2342620674 scopus 로고    scopus 로고
    • The many forms of bipolar disorder: A modern look at an old illness
    • Thomas P. The many forms of bipolar disorder: a modern look at an old illness. J Affect Disord. 2004;79(Suppl 1):S3-8.
    • (2004) J Affect Disord. , vol.79 , Issue.SUPPL. 1
    • Thomas, P.1
  • 36
    • 0034950547 scopus 로고    scopus 로고
    • Bipolar spectrum disorder: Improving its recognition and diagnosis
    • Hirschfeld RM. Bipolar spectrum disorder: improving its recognition and diagnosis. J Clin Psychiatry. 2001;62(Suppl 14):5-9.
    • (2001) J Clin Psychiatry. , vol.62 , Issue.SUPPL. 14 , pp. 5-9
    • Hirschfeld, R.M.1
  • 37
    • 21644480128 scopus 로고    scopus 로고
    • The impact of bipolar depression
    • Post RM. The impact of bipolar depression. J Clin Psychiatry. 2005;66(Suppl 5):5-10.
    • (2005) J Clin Psychiatry. , vol.66 , Issue.SUPPL. 5 , pp. 5-10
    • Post, R.M.1
  • 38
    • 73049125840 scopus 로고
    • The effect of nicotinic acid on the temperature of the skin of patients with schizophrenia in different states
    • Kashshai D, Mate B. The effect of nicotinic acid on the temperature of the skin of patients with schizophrenia in different states. Zh Nevropatol Psikhiatr Im S S Korsakova. 1961;61:1688-98.
    • (1961) Zh Nevropatol Psikhiatr Im S S Korsakova. , vol.61 , pp. 1688-1698
    • Kashshai, D.1    Mate, B.2
  • 39
    • 0019830037 scopus 로고
    • Niacin flushing and schizophrenia
    • Vaddadi KS. Niacin flushing and schizophrenia. Med Hypotheses. 1981;7:599-600.
    • (1981) Med Hypotheses. , vol.7 , pp. 599-600
    • Vaddadi, K.S.1
  • 40
    • 0022551305 scopus 로고
    • Niacin skin flush is not diagnostic of schizophrenia
    • Wilson DW, Douglass AB. Niacin skin flush is not diagnostic of schizophrenia. Biol Psychiatry. 1986;21:974-7.
    • (1986) Biol Psychiatry. , vol.21 , pp. 974-977
    • Wilson, D.W.1    Douglass, A.B.2
  • 41
    • 85027952177 scopus 로고    scopus 로고
    • Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: Systematic review and meta-analyses
    • Fleeman N, Dundar Y, Dickson R, Jorgensen A, Pushpakom S, McLeod C, et al. Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses. Pharmacogenomics J. 2010;11:1-14.
    • (2010) Pharmacogenomics J. , vol.11 , pp. 1-14
    • Fleeman, N.1    Dundar, Y.2    Dickson, R.3    Jorgensen, A.4    Pushpakom, S.5    McLeod, C.6
  • 42
    • 77951844279 scopus 로고    scopus 로고
    • Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
    • Kato M, Serretti A. Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol Psychiatry. 2010;15:473-500.
    • (2010) Mol Psychiatry. , vol.15 , pp. 473-500
    • Kato, M.1    Serretti, A.2
  • 43
    • 62449280788 scopus 로고    scopus 로고
    • Quantitation of HER2 expression or HER2:HER2 dimers and differential survival in a cohort of metastatic breast cancer patients carefully selected for trastuzumab treatment primarily by FISH
    • Desmedt C, Sperinde J, Piette F, Huang W, Jin X, Tan Y, et al. Quantitation of HER2 expression or HER2:HER2 dimers and differential survival in a cohort of metastatic breast cancer patients carefully selected for trastuzumab treatment primarily by FISH. Diagn Mol Pathol. 2009;18:22-9.
    • (2009) Diagn Mol Pathol. , vol.18 , pp. 22-29
    • Desmedt, C.1    Sperinde, J.2    Piette, F.3    Huang, W.4    Jin, X.5    Tan, Y.6
  • 45
    • 34347333627 scopus 로고    scopus 로고
    • First-and second-trimester evaluation of risk for Down syndrome
    • First and Second Trimester Evaluation of Risk (FASTER) Research Consortium
    • Ball RH, Caughey AB, Malone FD, Nyberg DA, Comstock CH, Saade GR, et al.; First and Second Trimester Evaluation of Risk (FASTER) Research Consortium. First-and second-trimester evaluation of risk for Down syndrome. Obstet Gynecol. 2007;110(1):10-7.
    • (2007) Obstet Gynecol. , vol.110 , Issue.1 , pp. 10-17
    • Ball, R.H.1    Caughey, A.B.2    Malone, F.D.3    Nyberg, D.A.4    Comstock, C.H.5    Saade, G.R.6
  • 46
    • 34249887687 scopus 로고    scopus 로고
    • Analytical validation of the Oncotype DX genomic diagnostic test for recurrence prognosis and therapeutic response prediction in node-negative, estrogen receptor-positive breast cancer
    • Cronin M, Sangli C, Liu ML, Pho M, Dutta D, Nguyen A, et al. Analytical validation of the Oncotype DX genomic diagnostic test for recurrence prognosis and therapeutic response prediction in node-negative, estrogen receptor-positive breast cancer. Clin Chem. 2007;53(6):1084-91.
    • (2007) Clin Chem. , vol.53 , Issue.6 , pp. 1084-1091
    • Cronin, M.1    Sangli, C.2    Liu, M.L.3    Pho, M.4    Dutta, D.5    Nguyen, A.6
  • 47
    • 0024345068 scopus 로고
    • Clinical utility of assays of glycosylated haemoglobin and serum fructosamine compared: Use of data on biological variation
    • Howey JE, Bennet WM, Browning MC, Jung RT, Fraser CG. Clinical utility of assays of glycosylated haemoglobin and serum fructosamine compared: use of data on biological variation. Diabet Med. 1989;6(9):793-6.
    • (1989) Diabet Med. , vol.6 , Issue.9 , pp. 793-796
    • Howey, J.E.1    Bennet, W.M.2    Browning, M.C.3    Jung, R.T.4    Fraser, C.G.5
  • 49
    • 79954576068 scopus 로고    scopus 로고
    • Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia
    • Guest PC, Schwarz E, Krishnamurthy D, Harris LW, Leweke FM, Rothermundt M, et al. Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia. Psychoneuroendocrinology. 2011;36(7):1092-6.
    • (2011) Psychoneuroendocrinology. , vol.36 , Issue.7 , pp. 1092-1096
    • Guest, P.C.1    Schwarz, E.2    Krishnamurthy, D.3    Harris, L.W.4    Leweke, F.M.5    Rothermundt, M.6
  • 51
    • 33750703145 scopus 로고    scopus 로고
    • The blood of the insane
    • Noll R. The blood of the insane. Hist Psychiatry. 2006;17:395-418.
    • (2006) Hist Psychiatry. , vol.17 , pp. 395-418
    • Noll, R.1
  • 52
    • 80055098801 scopus 로고
    • Clinical observations on the blood of the insane
    • Macphail SR. Clinical observations on the blood of the insane. Br J Psychiatry. 1884;30:378-89.
    • (1884) Br J Psychiatry. , vol.30 , pp. 378-389
    • McPhail, S.R.1
  • 54
    • 68449086236 scopus 로고    scopus 로고
    • International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, et al.; International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748-52.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6
  • 55
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 2009;460:753-7.
    • (2009) Nature. , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3    Sanders, A.R.4    Zheng, Y.5    Pe'er, I.6
  • 57
    • 79955438992 scopus 로고    scopus 로고
    • Developing predictive CSF biomarkers-A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine
    • Flood DG, Marek GJ, Williams M. Developing predictive CSF biomarkers-A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine. Biochem Pharmacol. 22011;81(12):1422-34.
    • (2201) Biochem Pharmacol.1 , vol.81 , Issue.12 , pp. 1422-1434
    • Flood, D.G.1    Marek, G.J.2    Williams, M.3
  • 58
    • 78649370566 scopus 로고    scopus 로고
    • Use and assessment of PSA in prostate cancer
    • Gjertson CK, Albertsen PC. Use and assessment of PSA in prostate cancer. Med Clin North Am. 2011;95:191-200.
    • (2011) Med Clin North Am. , vol.95 , pp. 191-200
    • Gjertson, C.K.1    Albertsen, P.C.2
  • 59
    • 78650328715 scopus 로고    scopus 로고
    • The road from discovery to clinical diagnostics: Lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers
    • Zhang Z, Chan DW. The road from discovery to clinical diagnostics: lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers. Cancer Epidemiol Biomarkers Prev. 2010;19:2995-9.
    • (2010) Cancer Epidemiol Biomarkers Prev. , vol.19 , pp. 2995-2999
    • Zhang, Z.1    Chan, D.W.2
  • 60
    • 77952138048 scopus 로고    scopus 로고
    • Renal biomarker qualification submission: A dialog between the FDAEMEA and Predictive Safety Testing Consortium
    • Dieterle F, Sistare F, Goodsaid F, Papaluca M, Ozer JS, Webb CP, et al. Renal biomarker qualification submission: a dialog between the FDAEMEA and Predictive Safety Testing Consortium. Nat Biotechnol. 2010;28:455-62.
    • (2010) Nat Biotechnol. , vol.28 , pp. 455-462
    • Dieterle, F.1    Sistare, F.2    Goodsaid, F.3    Papaluca, M.4    Ozer, J.S.5    Webb, C.P.6
  • 61
    • 0022240731 scopus 로고
    • Insulin resistance: Receptor and post-binding defects in human obesity and non-insulin-dependent diabetes mellitus
    • Truglia JA, Livingston JN, Lockwood DH. Insulin resistance: receptor and post-binding defects in human obesity and non-insulin-dependent diabetes mellitus. Am J Med. 1985;79:13-22.
    • (1985) Am J Med. , vol.79 , pp. 13-22
    • Truglia, J.A.1    Livingston, J.N.2    Lockwood, D.H.3
  • 62
    • 0022438560 scopus 로고
    • Glucose clamping: A modern method for research on insulin secretion and resistance
    • Khristov V. Glucose clamping: a modern method for research on insulin secretion and resistance. Vutr Boles. 1986;25:32-9.
    • (1986) Vutr Boles. , vol.25 , pp. 32-39
    • Khristov, V.1
  • 63
    • 77952228263 scopus 로고    scopus 로고
    • A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function
    • Ozer JS, Dieterle F, Troth S, Perentes E, Cordier A, Verdes P, et al. A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function. Nat Biotechnol. 2010;28:486-94.
    • (2010) Nat Biotechnol. , vol.28 , pp. 486-494
    • Ozer, J.S.1    Dieterle, F.2    Troth, S.3    Perentes, E.4    Cordier, A.5    Verdes, P.6
  • 64
    • 79957595752 scopus 로고    scopus 로고
    • Urinary biomarkers in hexachloro-1:3-butadiene-induced acute kidney injury in the female Hanover Wistar rat; correlation of α-glutathione S-transferase, albumin and kidney injury molecule-1 with histopathology and gene expression
    • Swain A, Turton J, Scudamore CL, Pereira I, Viswanathan N, Smyth R, et al. Urinary biomarkers in hexachloro-1:3-butadiene-induced acute kidney injury in the female Hanover Wistar rat; correlation of α-glutathione S-transferase, albumin and kidney injury molecule-1 with histopathology and gene expression. J Appl Toxicol. 2011;31(4):366-77.
    • (2011) J Appl Toxicol. , vol.31 , Issue.4 , pp. 366-377
    • Swain, A.1    Turton, J.2    Scudamore, C.L.3    Pereira, I.4    Viswanathan, N.5    Smyth, R.6
  • 65
    • 33747190312 scopus 로고    scopus 로고
    • Process map proposal for the validation of genomic biomarkers
    • Goodsaid F, Frueh F. Process map proposal for the validation of genomic biomarkers. Pharmacogenomics. 2006;7:773-82.
    • (2006) Pharmacogenomics. , vol.7 , pp. 773-782
    • Goodsaid, F.1    Frueh, F.2
  • 66
    • 47049120824 scopus 로고    scopus 로고
    • The Innovative Medicines Initiative (IMI): A new opportunity for scientific collaboration between academia and industry at the European level
    • Kamel N, Compton C, Middelveld R, Higenbottam T, Dahlén SE. The Innovative Medicines Initiative (IMI): a new opportunity for scientific collaboration between academia and industry at the European level. Eur Respir J. 2008;31:924-6.
    • (2008) Eur Respir J. , vol.31 , pp. 924-926
    • Kamel, N.1    Compton, C.2    Middelveld, R.3    Higenbottam, T.4    Dahlén, S.E.5
  • 67
    • 43049159565 scopus 로고    scopus 로고
    • The Innovative Medicines Initiative: A pre-competitive initiative to enhance the biomedical science base of Europe to expedite the development of new medicines for patients
    • Hunter AJ. The Innovative Medicines Initiative: a pre-competitive initiative to enhance the biomedical science base of Europe to expedite the development of new medicines for patients. Drug Discov Today. 2008;13:371-3.
    • (2008) Drug Discov Today. , vol.13 , pp. 371-373
    • Hunter, A.J.1
  • 68
    • 75749147077 scopus 로고    scopus 로고
    • Antibody-based protein multiplex platforms: Technical and operational challenges
    • Ellington AA, Kullo IJ, Bailey KR, Klee GG. Antibody-based protein multiplex platforms: technical and operational challenges. Clin Chem. 2010;56(2):186-93.
    • (2010) Clin Chem. , vol.56 , Issue.2 , pp. 186-193
    • Ellington, A.A.1    Kullo, I.J.2    Bailey, K.R.3    Klee, G.G.4
  • 70
    • 79953664182 scopus 로고    scopus 로고
    • Gene-environment interaction in psychological traits and disorders
    • Dick DM. Gene-environment interaction in psychological traits and disorders. Annu Rev Clin Psychol. 2011;7:383-409.
    • (2011) Annu Rev Clin Psychol. , vol.7 , pp. 383-409
    • Dick, D.M.1
  • 71
    • 0034305597 scopus 로고    scopus 로고
    • Negative symptoms in patients with schizophrenia with special reference to the primary versus secondary distinction
    • 26 Spec No 1
    • Fleischhacker W. Negative symptoms in patients with schizophrenia with special reference to the primary versus secondary distinction. Encephale. 2000;26 Spec No 1:12-4.
    • (2000) Encephale. , pp. 12-14
    • Fleischhacker, W.1
  • 72
    • 0004485680 scopus 로고    scopus 로고
    • Prevalence and description of psychotic features in bipolar mania
    • Dunayevich E, Keck PE Jr. Prevalence and description of psychotic features in bipolar mania. Curr Psychiatry Rep. 2000;2:286-90.
    • (2000) Curr Psychiatry Rep. , vol.2 , pp. 286-290
    • Dunayevich, E.1    Keck Jr., P.E.2
  • 73
    • 0032838529 scopus 로고    scopus 로고
    • Neuropsychological function in euthymic patients with bipolar disorder
    • Ferrier IN, Stanton BR, Kelly TP, Scott J. Neuropsychological function in euthymic patients with bipolar disorder. Br J Psychiatry. 1999;175:246-51.
    • (1999) Br J Psychiatry. , vol.175 , pp. 246-251
    • Ferrier, I.N.1    Stanton, B.R.2    Kelly, T.P.3    Scott, J.4
  • 74
    • 79952540456 scopus 로고    scopus 로고
    • Selected reaction monitoring applied to proteomics
    • Gallien S, Duriez E, Domon B. Selected reaction monitoring applied to proteomics. J Mass Spectrom. 2011;46:298-312.
    • (2011) J Mass Spectrom. , vol.46 , pp. 298-312
    • Gallien, S.1    Duriez, E.2    Domon, B.3
  • 78
    • 70349099635 scopus 로고    scopus 로고
    • Holographic enzyme inhibition assays for drug discovery
    • Tan EV, Lowe CR. Holographic enzyme inhibition assays for drug discovery. Anal Chem. 2009;81:7579-89.
    • (2009) Anal Chem. , vol.81 , pp. 7579-7589
    • Tan, E.V.1    Lowe, C.R.2
  • 79
    • 80055098986 scopus 로고    scopus 로고
    • The value of the schizophrenia diagnostic market
    • (Judge Business School, Cambridge University). MBA thesis;
    • Millan E. The value of the schizophrenia diagnostic market. Masters of Business Administration Individual Project (Judge Business School, Cambridge University). MBA thesis; 2007.
    • (2007) Masters of Business Administration Individual Project
    • Millan, E.1
  • 80
    • 80054837090 scopus 로고    scopus 로고
    • A new blood-based diagnostic aid for schizophrenia
    • Kelly D, Thedford S, Vyas G. A new blood-based diagnostic aid for schizophrenia. Psychiatr Serv. 2011;62:1107.
    • (2011) Psychiatr Serv. , vol.62 , pp. 1107
    • Kelly, D.1    Thedford, S.2    Vyas, G.3
  • 81
    • 78651394465 scopus 로고    scopus 로고
    • Bring on the biomarkers
    • Poste G. Bring on the biomarkers. Nature. 2011;469:156-7.
    • (2011) Nature. , vol.469 , pp. 156-157
    • Poste, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.