CCN4 induces vascular cell adhesion molecule-1 expression in human synovial fibroblasts and promotes monocyte adhesion

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 5, 2013, Pages 966-975

  Liu, Ju Fang ^a   Hou, Sheng Mou ^a   Tsai, Chun Hao ^b,c   Huang, Chun Yin ^c,d   Hsu, Chin Jung ^c   Tang, Chih Hsin ^c,e  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

CCN4; Integrin; OA; Syk; VCAM 1

Indexed keywords

ALPHAVBETA5 INTEGRIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CCN PROTEIN; CCN4 PROTEIN; CURCUMIN; PROTEIN KINASE C DELTA; PROTEIN KINASE SYK; PROTEIN KINASE SYK INHIBITOR; ROTTLERIN; STRESS ACTIVATED PROTEIN KINASE; TANSHINONE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL ADHESION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

CCN INTERCELLULAR SIGNALING PROTEINS; CELL ADHESION; CONNECTIVE TISSUE GROWTH FACTOR; CYSTEINE-RICH PROTEIN 61; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MONOCYTES; NEPHROBLASTOMA OVEREXPRESSED PROTEIN; OSTEOARTHRITIS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; SYNOVIAL FLUID; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84874369152     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2012.12.023     Document Type: Article

References (36)

1. Mor A., Abramson S.B., Pillinger M.H. The fibroblast-like synovial cell in rheumatoid arthritis: a key player in inflammation and joint destruction. Clin. Immunol. 2005, 115:118-128.
2. Shen P.C., Wu C.L., Jou I.M., Lee C.H., Juan H.Y., Lee P.J., Chen S.H., Hsieh J.L. T helper cells promote disease progression of osteoarthritis by inducing macrophage inflammatory protein-1gamma. Osteoarthr. Cartil. 2011, 19:728-736.
3. Choy E.H., Panayi G.S. Cytokine pathways and joint inflammation in rheumatoid arthritis. N. Engl. J. Med. 2001, 344:907-916.
4. Sakkas L.I., Platsoucas C.D. The role of T cells in the pathogenesis of osteoarthritis. Arthritis Rheum. 2007, 56:409-424.
5. Sucosky P., Balachandran K., Elhammali A., Jo H., Yoganathan A.P. Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathway. Arterioscler. Thromb. Vasc. Biol. 2009, 29:254-260.
6. Qureshi M.H., Cook-Mills J., Doherty D.E., Garvy B.A. TNF-alpha-dependent ICAM-1- and VCAM-1-mediated inflammatory responses are delayed in neonatal mice infected with Pneumocystis carinii. J. Immunol. 2003, 171:4700-4707.
7. Schett G., Kiechl S., Bonora E., Zwerina J., Mayr A., Axmann R., Weger S., Oberhollenzer F., Lorenzini R., Willeit J. Vascular cell adhesion molecule 1 as a predictor of severe osteoarthritis of the hip and knee joints. Arthritis Rheum. 2009, 60:2381-2389.
8. Kalichman L., Pantsulaia I., Kobyliansky E. Association between vascular cell adhesion molecule 1 and radiographic hand osteoarthritis. Clin. Exp. Rheumatol. 2011, 29:544-546.
9. Karatay S., Kiziltunc A., Yildirim K., Karanfil R.C., Senel K. Effects of different hyaluronic acid products on synovial fluid levels of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in knee osteoarthritis. Ann. Clin. Lab. Sci. 2004, 34:330-335.
10. Blom A.B., Brockbank S.M., van Lent P.L., van Beuningen H.M., Geurts J., Takahashi N., van der Kraan P.M., van de Loo F.A., Schreurs B.W., Clements K., Newham P., van den Berg W.B. Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1. Arthritis Rheum. 2009, 60:501-512.
11. Xu L., Corcoran R.B., Welsh J.W., Pennica D., Levine A.J. WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene. Genes Dev. 2000, 14:585-595.
12. Ono M., Inkson C.A., Kilts T.M., Young M.F. WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. J. Bone Miner. Res. 2011, 26:193-208.
13. Tang C.H., Chiu Y.C., Tan T.W., Yang R.S., Fu W.M. Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, AMPK, p38, and NF-kappa B pathway. J. Immunol. 2007, 179:5483-5492.
14. Tang C.H., Hsu C.J., Fong Y.C. The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts. Arthritis Rheum. 2010, 62:3615-3624.
15. Hsieh M.T., Hsieh C.L., Lin L.W., Wu C.R., Huang G.S. Differential gene expression of scopolamine-treated rat hippocampus-application of cDNA microarray technology. Life Sci. 2003, 73:1007-1016.
16. Wang Y.C., Lee P.J., Shih C.M., Chen H.Y., Lee C.C., Chang Y.Y., Hsu Y.T., Liang Y.J., Wang L.Y., Han W.H. Damage formation and repair efficiency in the p53 gene of cell lines and blood lymphocytes assayed by multiplex long quantitative polymerase chain reaction. Anal. Biochem. 2003, 319:206-215.
17. Huang H.C., Shi G.Y., Jiang S.J., Shi C.S., Wu C.M., Yang H.Y., Wu H.L. Thrombomodulin-mediated cell adhesion: involvement of its lectin-like domain. J. Biol. Chem. 2003, 278:46750-46759.
18. Tseng C.P., Huang C.L., Huang C.H., Cheng J.C., Stern A., Tseng C.H., Chiu D.T. Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells. FEBS Lett. 2003, 541:21-27.
19. Chen P.C., Lin T.H., Cheng H.C., Tang C.H. CCN3 increases cell motility and ICAM-1 expression in prostate cancer cells. Carcinogenesis 2012, 33:937-945.
20. Lin W.N., Luo S.F., Lin C.C., Hsiao L.D., Yang C.M. Differential involvement of PKC-dependent MAPKs activation in lipopolysaccharide-induced AP-1 expression in human tracheal smooth muscle cells. Cell. Signal. 2009, 21:1385-1395.
21. Leask A. Will o' the wisp: CCN4 as a novel molecular target in osteoarthritis. J. Cell. Commun. Signal. 2011, 5:51-52.
22. Zou W., Kitaura H., Reeve J., Long F., Tybulewicz V.L., Shattil S.J., Ginsberg M.H., Ross F.P., Teitelbaum S.L. Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J. Cell Biol. 2007, 176:877-888.
23. Willeke T., Schymeinsky J., Prange P., Zahler S., Walzog B. A role for Syk-kinase in the control of the binding cycle of the beta2 integrins (CD11/CD18) in human polymorphonuclear neutrophils. J. Leukoc. Biol. 2003, 74:260-269.
24. Stupack D.G., Li E., Silletti S.A., Kehler J.A., Geahlen R.L., Hahn K., Nemerow G.R., Cheresh D.A. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase. J. Cell Biol. 1999, 144:777-788.
25. Mun S.H., Kim J.W., Nah S.S., Ko N.Y., Lee J.H., Kim J.D., Kim do K., Kim H.S., Choi J.D., Kim S.H., Lee C.K., Park S.H., Kim B.K., Kim Y.M., Choi W.S. Tumor necrosis factor alpha-induced interleukin-32 is positively regulated via the Syk/protein kinase Cdelta/JNK pathway in rheumatoid synovial fibroblasts. Arthritis Rheum. 2009, 60:678-685.
26. Kawaki H., Kubota S., Suzuki A., Suzuki M., Kohsaka K., Hoshi K., Fujii T., Lazar N., Ohgawara T., Maeda T., Perbal B., Takano-Yamamoto T., Takigawa M. Differential roles of CCN family proteins during osteoblast differentiation: involvement of Smad and MAPK signaling pathways. Bone 2011, 49:975-989.
27. Wagner M., Klein C.L., Kleinert H., Euchenhofer C., Forstermann U., Kirkpatrick C.J. Heavy metal ion induction of adhesion molecules and cytokines in human endothelial cells: the role of NF-kappaB, I kappaB-alpha and AP-1. Pathobiology 1997, 65:241-252.
28. Madry H., Luyten F.P., Facchini A. Biological aspects of early osteoarthritis. Knee Surg. Sports Traumatol. Arthrosc. 2012, 20:407-422.
29. Brigstock D.R. The CCN family: a new stimulus package. J. Endocrinol. 2003, 178:169-175.
30. Giancotti F.G., Ruoslahti E. A single-chain integrin?. New Biol. 1991, 3:525-526.
31. Clark E.A., Shattil S.J., Ginsberg M.H., Bolen J., Brugge J.S. Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3. J. Biol. Chem. 1994, 269:28859-28864.
32. Berk B.C., Taubman M.B., Cragoe E.J., Fenton J.W., Griendling K.K. Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways. J. Biol. Chem. 1990, 265:17334-17340.
33. Leitges M., Elis W., Gimborn K., Huber M. Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-delta in hemopoietic cells. Lab. Invest. 2001, 81:1087-1095.
34. Ahmad M., Theofanidis P., Medford R.M. Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alpha. J. Biol. Chem. 1998, 273:4616-4621.
35. Lazzerini G., Del Turco S., Basta G., O'Loghlen A., Zampolli A., Caterina R.D. Prominent role of NF-kappaB in the induction of endothelial activation by endogenous nitric oxide inhibition. Nitric Oxide 2009, 21:184-191.
36. Wagner E.F. Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun). Ann. Rheum. Dis. 2010, 69(Suppl. 1):i86-i88.