A comparative evaluation of the dopamine D2/3 agonist radiotracer [11C](-)-N-propyl-norapomorphine and antagonist [ 11C]raclopride to measure amphetamine-induced dopamine release in the human striatum

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 2, 2010, Pages 533-539

  Narendran, Rajesh ^a   Mason, N Scott ^a   Laymon, Charles M ^a   Lopresti, Brian J ^a   Velasquez, Natalie D ^a   May, Maureen A ^a   Kendro, Steve ^a   Martinez, Diana ^b   Mathis, Chester A ^a   Frankle, W Gordon ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; DEXAMPHETAMINE; DOPAMINE; N PROPYL NORAPOMORPHINE C 11; RACLOPRIDE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BINDING AFFINITY; CAUDATE NUCLEUS; CLINICAL ASSESSMENT; CLINICAL EVALUATION; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DRUG BINDING; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; FEMALE; HUMAN; HUMAN EXPERIMENT; IMPEDANCE; IN VIVO STUDY; ISOTOPE LABELING; KINETICS; MALE; MEMBRANE POTENTIAL; NORMAL HUMAN; OUTCOME ASSESSMENT; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PUTAMEN; SYNAPTIC POTENTIAL;

ADULT; AMPHETAMINE; APOMORPHINE; CARBON RADIOISOTOPES; CORPUS STRIATUM; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; FEMALE; HUMANS; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; RACLOPRIDE; YOUNG ADULT;

EID: 77951088919     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.163501     Document Type: Article

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