Corticosteroid therapy in acute respiratory distress syndrome

CMAJ. Canadian Medical Association Journal

Volumn 185, Issue 3, 2013, Pages 216-221

  Lamontagne, Francois ^a   Brower, Roy ^b   Meade, Maureen ^c  

^a Centre Hospitalier Universitaire de Sherbrooke   (Canada)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; METHYLPREDNISOLONE; PLACEBO; PREDNISOLONE;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; CLINICAL PRACTICE; CORTICOSTEROID THERAPY; DRUG FATALITY; DRUG MEGADOSE; DRUG RESPONSE; GASTROINTESTINAL HEMORRHAGE; HUMAN; INFECTION; MENTAL DISEASE; META ANALYSIS (TOPIC); METABOLIC DISORDER; MORTALITY; NEUROMUSCULAR DISEASE; NEUROPATHY; NONHUMAN; PATIENT SELECTION; PREDICTION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW (TOPIC);

EID: 84874320049     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: 10.1503/cmaj.120582     Document Type: Review

References (50)

1. Ketoconazole for early treatment of acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. The ARDS Network. JAMA 2000;283:1995-2002.
2. Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. Crit Care Med 2002;30:1-6.
3. Adhikari NK, Burns KE, Friedrich JO, et al. Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ 2007;334:779.
4. Annane D. Glucocorticoids for ARDS: just do it! Chest 2007; 131: 945-6. (Pubitemid 46608687)
5. Sibbald WJ, Anderson RR, Reid B, et al. Alveolo-capillary permeability in human septic ARDS. Effect of high-dose corticosteroid therapy. Chest 1981;79:133-42.
6. Rocco PR, Souza AB, Faffe DS, et al. Effect of corticosteroid on lung parenchyma remodeling at an early phase of acute lung injury. Am J Respir Crit Care Med 2003;168:677-84.
7. Meduri GU, Tolley EA, Chrousos GP, et al. Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am J Respir Crit Care Med 2002;165:983-91.
8. Meduri GU, Tolley EA, Chinn A, et al. Procollagen types I and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment. Am J Respir Crit Care Med 1998;158:1432-41.
9. Bernard GR, Luce JM, Sprung CL, et al. High-dose cortico-steroids in patients with the adult respiratory distress syndrome. N Engl J Med 1987;317:1565-70.
10. Laggner AN, Lenz K, Base W, et al. Effect of high-dose prednisolone on lung fluid in patients with non-cardiogenic lung edema [article in German]. Wien Klin Wochenschr 1987;99:245-9. (Pubitemid 17043644)
11. Meduri GU, Golden E, Freire AX, et al. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest 2007;131:954-63.
12. Meduri GU, Headley AS, Golden E, et al. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial. JAMA 1998; 280: 159-65.
13. Steinberg KP, Hudson LD, Goodman RB, et al. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006;354:1671-84.
14. Weigelt JA, Norcross JF, Borman KR, et al. Early steroid therapy for respiratory failure. Arch Surg 1985;120:536-40.
15. Meduri GU, Marik PE, Chrousos GP et al. Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature. Intens Care Med 2008;34:61-9.
16. Peter JV, John P, Graham PL, et al. Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults: meta-analysis. BMJ 2008;336:1006-9. (Pubitemid 351656093)
17. Lamontagne F, Briel M, Guyatt GH, et al. Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: a meta-analysis of randomized controlled trials. J Crit Care 2010;25:420-35.
18. Tang BM, Craig JC, Eslick GD, et al. Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: a systematic review and meta-analysis. Crit Care Med 2009;37:1594- 603.
19. Agarwal R, Nath A, Aggarwal AN, et al. Do glucocorticoids decrease mortality in acute respiratory distress syndrome? A meta-analysis. Respirology 2007;12-585-90.
20. Meduri GU, Marik PE, Annane D. Prolonged glucocorticoid treatment in acute respiratory distress syndrome: Evidence supporting effectiveness and safety. Crit Care Med 2009;37:1800-3.
21. McGee S, Hirschmann J. Use of corticosteroids in treating infectious diseases. Arch Intern Med 2008;168:1034-46.
22. Fardet L, Kassar A, Cabane J, et al. Corticosteroid-induced adverse events in adults: frequency, screening and prevention. Drug Saf 2007;30:861-81.
23. Cook D, Lauzier F, Rocha MG, et al. Serious adverse events in academic critical care research. CMAJ 2008;178:1181-4. (Pubitemid 351580078)
24. Rady MY, Johnson DJ, Patel B, et al. Corticosteroids influence the mortality and morbidity of acute critical illness. Crit Care 2006; 10:R101.
25. Edwards P, Arango M, Balica L, et al. Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. Lancet 2005;365:1957-9.
26. Roberts I, Yates D, Sandercock P, et al. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet 2004;364:1321-8.
27. Brown PH, Teelucksingh S, Matusiewicz SP, et al. Cutaneous vaso constrictor response to glucocorticoids in asthma. Lancet 1991; 337:576-80.
28. Chriguer RS, Elias LL, da Silva IM Jr, et al. Glucocorticoid sensitivity in young healthy individuals: in vitro and in vivo studies. J Clin Endocrinol Metab 2005;90:5978-84.
29. Corrigan CJ, Brown PH, Barnes NC, et al. Glucocorticoid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am Rev Respir Dis 1991;144:1016-25.
30. DeRijk RH, Eskandari F, Sternberg EM. Corticosteroid resistance in a subpopulation of multiple sclerosis patients as measured by ex vivo dexamethasone inhibition of LPS induced IL-6 production. J Neuroimmunol 2004;151:180-8. (Pubitemid 38624412)
31. Hearing SD, Norman M, Probert CS, et al. Predicting therapeutic outcome in severe ulcerative colitis by measuring in vitro steroid sensitivity of proliferating peripheral blood lymphocytes. Gut 1999;45:382-8. (Pubitemid 29400714)
32. Place VA, Velazquez JG, Burdick KH. Precise evaluation of topically applied corticosteroid potency. Modification of the Stoughton-McKenzie assay. Arch Dermatol 1970;101:531-7.
33. Smit P, Russcher H, de Jong FH, et al. Differential regulation of synthetic glucocorticoids on gene expression levels of glucocorticoid-induced leucine zipper and interleukin-2. J Clin Endocrinol Metab 2005;90:2994-3000.
34. Vermeer H, Hendriks-Stegeman BI, van der Burg B, et al. Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J Clin Endocrinol Metab 2003;88:277-84.
35. Vermeer H, Hendriks-Stegeman BI, van Suylekom D, et al. An in vitro bioassay to determine individual sensitivity to glucocorticoids: induction of FKBP51 mRNA in peripheral blood mononuclear cells. Mol Cell Endocrinol 2004;218:49-55.
36. Vermeer H, Hendriks-Stegeman BI, Verrijn Stuart AA, et al. A comparison of in vitro bioassays to determine cellular glucocorticoid sensitivity. Eur J Endocrinol 2004;150:41-7. (Pubitemid 38159739)
37. Hearing SD, Norman M, Smyth C, et al. Wide variation in lymphocyte steroid sensitivity among healthy human volunteers. J Clin Endocrinol Metab 1999;84:4149-54.
38. Molijn GJ, Spek JJ, van Uffelen JC, et al. Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock. J Clin Endocrinol Metab 1995;80:1799-803.
39. Schleimer RP, Schulman ES, MacGlashan DW Jr., et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. J Clin Invest 1983; 71: 1830-5. (Pubitemid 13056786)
40. Hon YY, Jusko WJ, Spratlin VE, et al. Altered methylprednisolone pharmacodynamics in healthy subjects with histamine N-methyltransferase C314T genetic polymorphism. J Clin Pharmacol 2006;46:408-17.
41. Manenschijn L, van den Akker EL, Lamberts SW, et al. Clinical features associated with glucocorticoid receptor polymorphisms. An overview. Ann N Y Acad Sci 2009;1179:179-98.
42. Meduri GU, Yates CR. Systemic inflammation-associated glucocorticoid resistance and outcome of ARDS. Ann N Y Acad Sci 2004;1024:24-53.
43. Revollo JR, Cidlowski JA. Mechanisms generating diversity in glucocorticoid receptor signaling. Ann N Y Acad Sci 2009; 1179: 167-78.
44. Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 2005; 353: 1711-23.
45. Zhou J, Cidlowski JA. The human glucocorticoid receptor: one gene, multiple proteins and diverse responses. Steroids 2005; 70: 407-17.
46. Alvarez J, Surs W, Leung DY, et al. Steroid-resistant asthma: immunologic and pharmacologic features. J Allergy Clin Immunol 1992;89:714-21.
47. Bhavsar P, Hew M, Khorasani N, et al. Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma. Thorax 2008;63:784-90.
48. Cornell RC, Stoughton RB. Correlation of the vasoconstriction assay and clinical activity in psoriasis. Arch Dermatol 1985; 121: 63-7. (Pubitemid 16225021)
49. Kirkham BW, Corkill MM, Davison SC, et al. Response to glucocorticoid treatment in rheumatoid arthritis: in vitro cell mediated immune assay predicts in vivo responses. J Rheumatol 1991; 18:821-5.
50. Thompson BT. Corticosteroids for ARDS. Minerva Anestesiol 2010; 76:441-7.