BH3-Mimetics- and Cisplatin-Induced Cell Death Proceeds through Different Pathways Depending on the Availability of Death-Related Cellular Components

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Andreu Fernández, Vicente ^a   Genovés, Ainhoa ^a   Messeguer, Angel ^b   Orzáez, Mar ^a   Sancho, Mónica ^a   Pérez Payá, Enrique ^a,c  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b CSIC   (Spain)

^c INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CISPLATIN; OBATOCLAX; PROTEIN BAK; PROTEIN BAX;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL ASSAY; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENTIATION; EMBRYO; FEMALE; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; UTERINE CERVIX CARCINOMA;

ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CISPLATIN; FIBROBLASTS; HELA CELLS; HUMANS; MICE; MICE, KNOCKOUT; MOLECULAR MIMICRY; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRROLES; SIGNAL TRANSDUCTION;

EID: 84874317892     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056881     Document Type: Article

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