An extracellular ion pathway plays a central role in the cooperative gating of a K2P K+ channel by extracellular pH

Journal of Biological Chemistry

Volumn 288, Issue 8, 2013, Pages 5984-5991

  Gonzá lez, Wendy ^a   Zúniga, Leandro ^b   Cid, L Pablo ^b   Arévalo, Barbara ^a   Niemeyer, María Isabel ^b   Sepúlveda, Francisco V ^b  

^a CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

^b UNIVERSIDAD DE TALCA   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

CHANNEL OPENING; ELECTROSTATIC EFFECT; EXTRACELLULAR; EXTRACELLULAR PH; K+ CHANNELS;

AMINO ACIDS;

IONS;

HISTIDINE; POTASSIUM ION; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL TASK 3;

ARTICLE; CELL ASSAY; CELL MEMBRANE POTENTIAL; CELL PH; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INTERACTION; RESIDUE ANALYSIS; STATIC ELECTRICITY; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GUINEA PIGS; HUMANS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; IONS; MEMBRANE POTENTIALS; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROBABILITY; PROTONS; STATIC ELECTRICITY;

EID: 84874306177     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.445528     Document Type: Article

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