Release study of naproxen, a modern drug from pH sensitive pullulan acetate microsphere

International Journal of Drug Development and Research

Volumn 4, Issue 4, 2012, Pages 184-191

  Bishwambhar, Mishra ^a   Suneetha, Vuppu ^a  

^a VIT UNIVERSITY   (India)

Author keywords

Aureobasidium sps.; Naproxen; pH; Phosphate buffer saline; Pullulan

Indexed keywords

ACETIC ACID; BIOPOLYMER; DEXTRAN; DICHLOROMETHANE; FORMAMIDE; MICROSPHERE; NAPROXEN; PHOSPHATE BUFFERED SALINE; PLASMA SUBSTITUTE; PULLULAN;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; IN VITRO STUDY; INFRARED SPECTROSCOPY; PH;

EID: 84874300794     PISSN: None     EISSN: 09759344     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Jalil R, Nixon JR. Biodegradable poly(lactic acid) and Poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J microencapsulation 1990; 7: 297-325.
2. Rajesh RD, Rajesh HP. Two-stage optimization process for formulation of chitosan microspheres, AAPS Pharm Sci Tech 2003; 5: 1-9.
3. Xi K, Tabata Y, Uno K, Yoshimoto M, Sokawa Y, Ikada Y. Liver targeting of interferon through Pullulan conjugation. Pharm Res 1996; 13: 1846-1850.
4. Sinha VR, Bansal K, Kaushik R, Kumria R, Trehan A. Poly-?-caprolactone microspheres and nanospheres: an overview. Int J Pharm 2004; 273: 1-23.
5. Yi-Yan Y, Tai-Shung C, Ngee Ping Ng. Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. Biomaterials 2001; 22:231-241.
6. Suneetha V., Sindhuja K.V., Sanjeev K. Screening, characterization and optimization of pullulan producing microorganisms from plant leaves in chitoor district. Asian Journal of Microbiology Biotechnology and environmental sciences.2010;12:149-155.
7. Bishwambhar M., Suneetha V., Kalyani R. The role of microbial pullulan, a biopolymer in pharmaceutical approaches: A review. Journal of Applied Pharmaceutical Science 2011; 01:45-50.
8. Bishwambhar M., Suneetha V. The microbial pullulan as therapeutic tool in Medicine International Journal Of Ayurvedic And Herbal Medicine 2012; 2:180-186.
9. Bishwambhar M., Suneetha V., Ramalingam C. An overview of Mechanistic Characterization and optimization of Pullulan producing microorganism South Asian Journal of Experimental Biology 2011;01: 147i{dotless}151.
10. Sanjay S., Amod K., Suneetha V., Bishwambhar M., Gopinath R., Sharad Y., Bhaskar M. Synthesis and activation of Immobilized beads by natural dye extracts. International Journal of Drug Development & Research;2012:304-310.
11. Hongyan H, Xia C, Lee LJ. Design of a novel hydrogel-based intelligent system for controlled drug release. J Controlled Release 2004;95:391-402.
12. Traitel T, Cohen Y, Kost J. Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions. Biomaterials 2000;21:1679-87.
13. Kurkuri MD, Aminabhavi TM. Poly(vinyl alcohol) and poly(acrylic acid) sequential interpenetrating network pH-sensitive microspheres for the delivery of diclofenac sodium to the intestine. J Controlled Release 2004;96:9-20.
14. Kim EJ, Cho SH, Yuk SH. Polymeric microspheres composed of pH/temperature-sensitive polymer complex. Biomaterials 2001;22:2495-9.
15. Hoffart V, Ubrich N, Simonin C, Babak V, Vigneron C, Hoffman M, et al. Low molecular weight heparinloaded polymeric nanoparticles: formulation, characterization, and release characteristics. Drug DevInd Pharm 2002; 28:1091-2000.
16. Liu SQ, Yong YY, Liu XM, Tong YW. Preparation and characterization of temperature-sensitive poly(N-isopropylacrylamide)-b-poly(D, L-lactide) microspheres for protein delivery. Biomacromolecules 2003;4:1784-93.
17. Hombreiro-pérez M, Siepmann J, Zinutti C, Lamprecht A, Ubrich N, Hoffman M, et al. Nondegradable microparticles containing a hydrophilic and/or a lipophilic drug: preparation, characterization and drug release modeling. J Control Rel 2003; 88:413-428.
18. Choi C, Chae SY, Nah JW. Thermosensitive poly(Nisopropylacrylamide)-bpoly(3-caprolactone) nanoparticles for efficient drug delivery system. Polymer 2006;47:4571-80.
19. Ramkissoon-Ganorkar C, Liu F, Baudys M, Kim SW. Modulating insulin release profile from pH/thermosensitive polymeric beads through polymer molecular weight. J Controlled Release 1999;39:287-98.
20. Iemma F, Spizzirri UG, Puoci F, Muzzalupo R, Trombino S, Cassana R, et al. pH-sensitive hydrogels based bovine serum albumin for oral drug delivery. Int J Pharm 2006;312:151-7.
21. Wei J-S, Zeng H-B, Liu S-Q, Wang XG, Tay EH, Yang YY. Temperature-and pH-sensitive core-shell nanoparticles self-assembled from poly(Nisopropylacrylamide-co-acrylic acid-co-cholesteryl acrylate) for intracellular delivery of anticancer drugs. Front Biosci 2005;10:3058-67.
22. Manna AK, Ray S, Gupta BK, Ghosh LK. Product development studies on controlled release delivery system of Nitrofurantoin. J Pharm Res 2005; 4: 16-20.
23. Pey Y, Chen J, Yang L, Shi L, Tao K, Hui B, et al. The effect of pH on the LCST of poly(Nisopropylacrylamide) and poly(Nisopropylacrylamide-co-acrylic acid). J Biomater Sci Polym Ed 2004;15:585-94.
24. Cai H, Zhang ZP, Chuan Sun P, Lin He B, Xia Zhu X. Synthesis and characterization of thermo-and pH-sensitive hydrogels based on chitosangrafted Nisopropylacrylamide via g-radiation. Radiat Phys Chem 2005;74: 26-30.
25. Pepper KW, Reichenberg D, Halle DK. Properties of ion-exchange resins in relation to their structure. Part IV. Swelling and shrinkage of sulphonated polystyrenes of different crosslinking. J Am Chem Soc 1952:3129-36.
26. Fundueanu G, Constantin M, Mihai D, Bortolotti F, Cortesi R, Ascenzi P, et al. Pullulan/cyclodextrin microspheres. A chromatographic approach for the evaluation of the drug/cyclodextrin interactions and the determination of the drug release profiles. J Chromatogr B 2003;791:407-19.
27. Mocanu G, Mihai D, Le Clerf D, Picton L, Muller G. Synthesis of new associative gel microspheres from carboxymethyl pullulan and their interactions with lysozyme. Eur Polym J 2004;40:283-9.
28. Suneetha V, Raj V. Statistical analysis on optimisation of Microbial Keratinase enzyme screened from Tirumala and Tirupati soil samples. Journal of Drug Development & Research 2012;4:253-258.
29. Kalyani R, Bishwambhar M, Suneetha V. Bio degrading ability of organo-sulphur compound of a newly isolated microbe Bacillus sp. KS1 from the oil contaminated Soil, Archives of Applied Science Research 2012;04:465-471.