Genetic predisposition to acute respiratory distress syndrome in patients with severe sepsis

Shock

Volumn 39, Issue 3, 2013, Pages 255-260

  Cardinal Fernández, Pablo ^a,b   Ferruelo, Antonio ^a,b   El Assar, Mariam ^a,b   Santiago, Catalina ^c   Gómez Gallego, Félix ^c   Martín Pellicer, Ana ^a,b   Frutos Vivar, Fernando ^a,b   Peñuelas, Oscar ^a,b   Nin, Nicolás ^a,d   Esteban, Andrés ^a,b   Lorente, José A ^a,b,c  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^c UNIVERSIDAD EUROPEA DE MADRID   (Spain)

^d HOSPITAL UNIVERSITARIO DE TORREJÓN   (Spain)

Author keywords

acute respiratory distress syndrome; acute respiratory failure; angiotensin converting enzyme; genetic polymorphism; Genetic polymorphisms; mortality; sepsis; single nucleotide polymorphism

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DNA; GLUCOSE; INTERLEUKIN 8; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; ALCOHOLISM; ALLELE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DNA EXTRACTION; DNA POLYMORPHISM; FEMALE; GENE DELETION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; SCORING SYSTEM; SEPSIS; SEX; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RENIN; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS; YOUNG ADULT;

EID: 84874256435     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3182866ff9     Document Type: Article

References (51)

1. Esteban A, Ferguson ND, Meade MO, Frutos-Vivar F, Apezteguia C, Brochard L, Raymondos K, Nin N, Hurtado J, Tomicic V. et al.: Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med 177(2): 170-177, 2008.
2. Phua J, Badia JR, Adhikari NK, Friedrich JO, Fowler RA, Singh JM, Scales DC, Stather DR, Li A, Jones A, et al.: Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med 179(3):220-227, 2009.
3. Zambon M, Vincent JL: Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 133(5):1120-1127, 2008.
4. FergusonND, Frutos-Vivar F, Esteban A, Gordo F, Honrubia T, Penuelas O, Algora A, García G, Bustos A, Rodríguez I: Clinical risk conditions for acute lung injury in the intensive care unit and hospital ward: a prospective observational study. Crit Care 11(5):R96, 2007.
5. Arcaroli J, Fessler MB, Abraham E: Genetic polymorphisms and sepsis. Shock 24(4):300-312, 2005.
6. Hildebrand F, Mommsen P, Frink M, van Griensven M, Krettek C: Genetic predisposition for development of complications in multiple trauma patients. Shock 35(5):440-448, 2011.
7. Cardinal-Fernandez P, Nin N, Lorente JA: Acute lung injury and acute respiratory distress syndrome: a genomic perspective. Med Intensiva 35(6):361-372, 2011.
8. Pipeling MR, Fan E: Therapies for refractory hypoxemia in acute respiratory distress syndrome. JAMA 304(22):2521-2527, 2010.
9. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, et al.: Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Hum Genet 125(2):131-151, 2009.
10. Colhoun HM, McKeigue PM, Davey Smith G: Problems of reporting genetic associations with complex outcomes. Lancet 361(9360):865-872, 2003.
11. Adamzik M, Frey U, Sixt S, Knemeyer L, Beiderlinden M, Peters J, Siffert W: ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS. Eur Respir J 29(3):482-488, 2007.
12. Gong MN, Zhou W, Williams PL, Thompson BT, Pothier L, Boyce P, Christiani DC. 308GA and TNFB polymorphisms in acute respiratory distress syndrome. Eur Respir J 26(3):382-389, 2005.
13. Hildebrand F, Stuhrmann M, van Griensven M, Meier S, Hasenkamp S, Krettek C, Pape HC: Association of IL-8-251A/T polymorphism with incidence of Acute Respiratory Distress Syndrome (ARDS) and IL-8 synthesis after multiple trauma. Cytokine 37(3):192-199, 2007.
14. Marshall RP, Webb S, Bellingan GJ, Montgomery HE, Chaudhari B, McAnulty RJ, Humphries SE, Hill MR, Laurent GJ: Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. Am J Respir Crit Care Med 166(5):646-650, 2002.
15. Medford AR, Keen LJ, Bidwell JL, Millar AB: Vascular endothelial growth factor gene polymorphism and acute respiratory distress syndrome. Thorax 60(3):244-248, 2005.
16. Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, Easley RB, McVerry BJ, Tuder RM, Standiford T, et al.: PreYB-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. Am J Respir Crit Care Med 171(4):361-370, 2005.
17. Zhai R, Gong MN, Zhou W, Thompson TB, Kraft P, Su L, Christiani DC: Genotypes and haplotypes of the VEGF gene are associated with higher mortality and lower VEGF plasma levels in patients with ARDS. Thorax 62(8):718-722, 2007.
18. Cardinal-Fernández P, Ferruelo A, El-Assar M, Santiago C, Gómez-Gallego F, Martín-Pellicer A, Frutos-Vivar F, Peñuelas O, Nin N, Lorente JA: Genetic Predisposition to Acute Respiratory Distress Syndrome in Patients with Severe Sepsis. Shock 2013 Jan 28 [epub ahead of print].
19. Members of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20(6):864-874, 1992.
20. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R: The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149(3 Pt 1):818-824, 1994.
21. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, et al.: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock. Crit Care Med 36(1):296-327, 2008.
22. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F: An insertion/deletion polymorphism in the angiotensin IYconverting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86(4): 1343-1346, 1990.
23. Jerng JS, Yu CJ, Wang HC, Chen KY, Cheng SL, Yang PC: Polymorphism of the angiotensin-converting enzyme gene affects the outcome of acute respiratory distress syndrome. Crit Care Med 34(4):1001-1006, 2006.
24. Hu Z, Jin X, Kang Y, Liu C, Zhou Y, Wu X, Liu J, Zhong M, Luo C, Deng L, et al.: Angiotensin-converting enzyme insertion/deletion polymorphism associated with acute respiratory distress syndrome among Caucasians. J Int Med Res 38(2):415-422, 2010.
25. Thelle DS: STROBE and STREGA: instruments for improving transparency and quality of reporting scientific results. Eur J Epidemiol 24(1):7-8, 2009.
26. 1000 Genomes Project Consortium, Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA: A map of human genome variation from population-scale sequencing. Nature 467(7319): 1061-1073, 2010.
27. 1000 Genomes Project Consortium. A Deep Catalog of Human Genetic Variation. Available at: http://www.1000genomes.org/. Accessed 10 Aug 2012.
28. Matsuda A, Kishi T, Jacob A, Aziz M, Wang P: Association between insertion/deletion polymorphism in angiotensin-converting enzyme gene and acute lung injury/acute respiratory distress syndrome: a meta-analysis. BMC Med Genet 13:76, 2012.
29. du Cheyron D, Fradin S, Ramakers M, Terzi N, Guillotin D, Bouchet B, et al.: Angiotensin converting enzyme insertion/deletion genetic polymorphism: its impact on renal function in critically ill patients. Crit Care Med 36(12): 3178-3183, 2008.
30. Fourrier F, Chopin C, Wallaert B, Mazurier C, Mangalaboyi J, Durocher A: Compared evolution of plasma fibronectin and angiotensin-converting enzyme levels in septic ARDS. Chest 87(2):191-195, 1985.
31. Yamamoto T, Wang L, Shimakura K, Sanaka M, Koike Y, Mineshita S: Angiotensin IIYinduced pulmonary edema in a rabbit model. Jpn J Pharmacol 73(1):33-40, 1997.
32. Marshall RP, Puddicombe A, Cookson WO, Laurent GJ: Adult familial cryptogenic fibrosing alveolitis in the United Kingdom. Thorax 55(2):143-146, 2000.
33. Shrikrishna D, Astin R, Kemp PR, Hopkinson NS: Renin-angiotensin system blockade: a novel therapeutic approach in chronic obstructive pulmonary disease. Clin Sci (Lond) 123(8):487-498, 2012.
34. Medhora M, Gao F, Jacobs ER, Moulder JE: Radiation damage to the lung: mitigation by angiotensin-converting enzyme (ACE) inhibitors. Respirology 17(1):66-71, 2012.
35. Caldeira D, Alarcao J, Vaz-Carneiro A, Costa J: Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis. BMJ 345:e4260, 2012.
36. Rafailidis PI, Matthaiou DK, Varbobitis I, Falagas ME: Use of ACE inhibitors and risk of community-acquired pneumonia: a review. Eur J Clin Pharmacol 64(6):565-573, 2008.
37. Wang R, Ibarra-Sunga O, Verlinski L, Pick R, Uhal BD: Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor. Am J Physiol Lung Cell Mol Physiol 279(1):L143-L151, 2000.
38. He X, Han B, Mura M, Xia S, Wang S, Ma T, Liu M, Liu Z: Angiotensinconverting enzyme inhibitor captopril prevents oleic acidYinduced severe acute lung injury in rats. Shock 28(1):106-111, 2007.
39. Hagiwara S, Iwasaka H, Matumoto S, Hidaka S, Noguchi T: Effects of an angiotensin-converting enzyme inhibitor on the inflammatory response in in vivo and in vitro models. Crit Care Med 37(2):626-633, 2009.
40. Trillo-Alvarez CA, Kashyap R, Kojicic M, Li G, Thakur S, Cartin-Ceba R, Gajic O, et al.: Chronic use of angiotensin pathway inhibitors is associated with a decreased risk of acute respiratory distress syndrome. Am J Respir Crit Care Med 179:A4638, 2009.
41. Gong MN, Bajwa EK, Thompson DB, Christiani DC: Use of ACE inhibitors and development and outcome in ARDS. Am J Respir Crit Care Med 179: A5095, 2009.
42. Flores C, Ma SF, Maresso K, Wade MS, Villar J, Garcia JG: IL6 gene-wide haplotype is associated with susceptibility to acute lung injury. Transl Res 152(1):11-17, 2008.
43. Clark MF, Baudouin SV: A systematic review of the quality of genetic association studies in human sepsis. Intensive Care Med 32(11):1706-1712, 2006.
44. Sutherland AM, Walley KR: Bench-to-bedside review: association of genetic variation with sepsis. Crit Care 13(2):210, 2009.
45. Gong MN, Zhou W, Williams PL, Thompson BT, Pothier L, Christiani DC: Polymorphisms in the mannose binding lectin-2 gene and acute respiratory distress syndrome. Crit Care Med 35(1):48-56, 2007.
46. Magnotti LJ, Fischer PE, Zarzaur BL, Fabian TC, Croce MA: Impact of gender on outcomes after blunt injury: a definitive analysis of more than 36,000 trauma patients. J Am Coll Surg 206(5):984-991, 2008.
47. Kojicic M, Li G, Hanson AC, Lee KM, Thakur L, Vedre J, Ahmed A, Baddour LM, Ryu JH, Gajic O: Risk factors for the development of acute lung injury in patients with infectious pneumonia. Crit Care 16(2):R46, 2012.
48. Moss M, Mannino DM: Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979-1996). Crit Care Med 30(8):1679-1685, 2002.
49. Yilmaz M, Keegan MT, Iscimen R, Afessa B, Buck CF, Hubmayr RD, Gajic O: Toward the prevention of acute lung injury: protocol-guided limitation of large tidal volume ventilation and inappropriate transfusion. Crit Care Med 35(7): 1660-1666, 2007.
50. Honiden S, Gong MN: Diabetes, insulin, and development of acute lung injury. Crit Care Med 37(8):2455-2464, 2009.
51. Lagan AL, Quinlan GJ, Mumby S, Melley DD, Goldstraw P, Bellingan GJ, Hill MR, Briggs D, Pantelidis P, du Bois RM, et al.: Variation in iron homeostasis genes between patients with ARDS and healthy control subjects. Chest 133(6):1302-1311, 2008.