메뉴 건너뛰기




Volumn 190, Issue 5, 2013, Pages 2372-2380

Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-γ+CD4+ regulatory T cells to control transplant arteriosclerosis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; MISOPROSTOL; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

EID: 84874239821     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202996     Document Type: Article
Times cited : (99)

References (49)
  • 1
    • 33745953647 scopus 로고    scopus 로고
    • T cell costimulation in the development of cardiac allograft vasculopathy: Potential targets for therapeutic interventions
    • Isobe, M., H. Kosuge, and J. Suzuki. 2006. T cell costimulation in the development of cardiac allograft vasculopathy: potential targets for therapeutic interventions. Arterioscler. Thromb. Vasc. Biol. 26: 1447-1456.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1447-1456
    • Isobe, M.1    Kosuge, H.2    Suzuki, J.3
  • 2
    • 0028277677 scopus 로고
    • Coronary atherosclerosis in transplanted mouse hearts. I. Time course and immunogenetic and immunopathological considerations
    • Russell, P. S., C. M. Chase, H. J. Winn, and R. B. Colvin. 1994. Coronary atherosclerosis in transplanted mouse hearts. I. Time course and immunogenetic and immunopathological considerations. Am. J. Pathol. 144: 260-274.
    • (1994) Am. J. Pathol. , vol.144 , pp. 260-274
    • Russell, P.S.1    Chase, C.M.2    Winn, H.J.3    Colvin, R.B.4
  • 4
    • 79955402680 scopus 로고    scopus 로고
    • Therapeutic effects of umbilical cord bloodderived mesenchymal stem cell transplantation in experimental lupus nephritis
    • Chang, J. W., S. P. Hung, H. H. Wu, W. M. Wu, A. H. Yang, H. L. Tsai, L. Y. Yang, and O. K. Lee. 2011. Therapeutic effects of umbilical cord bloodderived mesenchymal stem cell transplantation in experimental lupus nephritis. Cell Transplant. 20: 245-257.
    • (2011) Cell Transplant. , vol.20 , pp. 245-257
    • Chang, J.W.1    Hung, S.P.2    Wu, H.H.3    Wu, W.M.4    Yang, A.H.5    Tsai, H.L.6    Yang, L.Y.7    Lee, O.K.8
  • 5
    • 77950377767 scopus 로고    scopus 로고
    • Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma
    • [Published erratum appears in 2010 Proc. Natl. Acad. Sci. USA 107: 8041.]
    • Nemeth, K., A. Keane-Myers, J. M. Brown, D. D. Metcalfe, J. D. Gorham, V. G. Bundoc, M. G. Hodges, I. Jelinek, S. Madala, S. Karpati, and E. Mezey. 2010. Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma. [Published erratum appears in 2010 Proc. Natl. Acad. Sci. USA 107: 8041.] Proc. Natl. Acad. Sci. USA 107: 5652-5657.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 5652-5657
    • Nemeth, K.1    Keane-Myers, A.2    Brown, J.M.3    Metcalfe, D.D.4    Gorham, J.D.5    Bundoc, V.G.6    Hodges, M.G.7    Jelinek, I.8    Madala, S.9    Karpati, S.10    Mezey, E.11
  • 7
    • 56149110595 scopus 로고    scopus 로고
    • Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells
    • Casiraghi, F., N. Azzollini, P. Cassis, B. Imberti, M. Morigi, D. Cugini, R. A. Cavinato, M. Todeschini, S. Solini, A. Sonzogni, et al. 2008. Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells. J. Immunol. 181: 3933-3946.
    • (2008) J. Immunol. , vol.181 , pp. 3933-3946
    • Casiraghi, F.1    Azzollini, N.2    Cassis, P.3    Imberti, B.4    Morigi, M.5    Cugini, D.6    Cavinato, R.A.7    Todeschini, M.8    Solini, S.9    Sonzogni, A.10
  • 8
    • 78650827566 scopus 로고    scopus 로고
    • Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression
    • Ge, W., J. Jiang, J. Arp, W. Liu, B. Garcia, and H. Wang. 2010. Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression. Transplantation 90: 1312-1320.
    • (2010) Transplantation , vol.90 , pp. 1312-1320
    • Ge, W.1    Jiang, J.2    Arp, J.3    Liu, W.4    Garcia, B.5    Wang, H.6
  • 9
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad, F., P. Plence, C. Bony, P. Tropel, F. Apparailly, J. Sany, D. Noël, and C. Jorgensen. 2003. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 102: 3837-3844.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3    Tropel, P.4    Apparailly, F.5    Sany, J.6    Noël, D.7    Jorgensen, C.8
  • 10
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal, S., and M. F. Pittenger. 2005. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105: 1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 11
    • 17844391825 scopus 로고    scopus 로고
    • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/ suppressive phenotype
    • Maccario, R., M. Podestà, A. Moretta, A. Cometa, P. Comoli, D. Montagna, L. Daudt, A. Ibatici, G. Piaggio, S. Pozzi, et al. 2005. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/ suppressive phenotype. Haematologica 90: 516-525.
    • (2005) Haematologica , vol.90 , pp. 516-525
    • MacCario, R.1    Podestà, M.2    Moretta, A.3    Cometa, A.4    Comoli, P.5    Montagna, D.6    Daudt, L.7    Ibatici, A.8    Piaggio, G.9    Pozzi, S.10
  • 12
    • 34548739534 scopus 로고    scopus 로고
    • Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem celllymphocyte interaction
    • Prevosto, C., M. Zancolli, P. Canevali, M. R. Zocchi, and A. Poggi. 2007. Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem celllymphocyte interaction. Haematologica 92: 881-888.
    • (2007) Haematologica , vol.92 , pp. 881-888
    • Prevosto, C.1    Zancolli, M.2    Canevali, P.3    Zocchi, M.R.4    Poggi, A.5
  • 14
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 18
    • 0347895101 scopus 로고    scopus 로고
    • Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
    • Kemper, C., A. C. Chan, J. M. Green, K. A. Brett, K. M. Murphy, and J. P. Atkinson. 2003. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421: 388-392.
    • (2003) Nature , vol.421 , pp. 388-392
    • Kemper, C.1    Chan, A.C.2    Green, J.M.3    Brett, K.A.4    Murphy, K.M.5    Atkinson, J.P.6
  • 20
    • 33749530539 scopus 로고    scopus 로고
    • Cutting edge: Abortive proliferation of CD46-induced Tr1-like cells due to a defective Akt/Survivin signaling pathway
    • Meiffren, G., M. Flacher, O. Azocar, C. Rabourdin-Combe, and M. Faure. 2006. Cutting edge: abortive proliferation of CD46-induced Tr1-like cells due to a defective Akt/Survivin signaling pathway. J. Immunol. 177: 4957-4961.
    • (2006) J. Immunol. , vol.177 , pp. 4957-4961
    • Meiffren, G.1    Flacher, M.2    Azocar, O.3    Rabourdin-Combe, C.4    Faure, M.5
  • 21
    • 66049149509 scopus 로고    scopus 로고
    • Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood
    • Häringer, B., L. Lozza, B. Steckel, and J. Geginat. 2009. Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood. J. Exp. Med. 206: 1009-1017.
    • (2009) J. Exp. Med. , vol.206 , pp. 1009-1017
    • Häringer, B.1    Lozza, L.2    Steckel, B.3    Geginat, J.4
  • 23
    • 79952317431 scopus 로고    scopus 로고
    • IL-27 induces the differentiation of Tr1-like cells from human naive CD4+ T cells via the phosphorylation of STAT1 and STAT3
    • Wang, H., R. Meng, Z. Li, B. Yang, Y. Liu, F. Huang, J. Zhang, H. Chen, and C. Wu. 2011. IL-27 induces the differentiation of Tr1-like cells from human naive CD4+ T cells via the phosphorylation of STAT1 and STAT3. Immunol. Lett. 136: 21-28.
    • (2011) Immunol. Lett. , vol.136 , pp. 21-28
    • Wang, H.1    Meng, R.2    Li, Z.3    Yang, B.4    Liu, Y.5    Huang, F.6    Zhang, J.7    Chen, H.8    Wu., C.9
  • 24
    • 79955971620 scopus 로고    scopus 로고
    • The impact of inflammatory licensing on heme oxygenase-1- mediated induction of regulatory T cells by human mesenchymal stem cells
    • Mougiakakos, D., R. Jitschin, C. C. Johansson, R. Okita, R. Kiessling, and K. Le Blanc. 2011. The impact of inflammatory licensing on heme oxygenase-1- mediated induction of regulatory T cells by human mesenchymal stem cells. Blood 117: 4826-4835.
    • (2011) Blood , vol.117 , pp. 4826-4835
    • Mougiakakos, D.1    Jitschin, R.2    Johansson, C.C.3    Okita, R.4    Kiessling, R.5    Le Blanc, K.6
  • 25
    • 61849123247 scopus 로고    scopus 로고
    • Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 +CD25(High) forkhead box P3+ regulatory T cells
    • English, K., J. M. Ryan, L. Tobin, M. J. Murphy, F. P. Barry, and B. P. Mahon. 2009. Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 +CD25(High) forkhead box P3+ regulatory T cells. Clin. Exp. Immunol. 156: 149-160.
    • (2009) Clin. Exp. Immunol. , vol.156 , pp. 149-160
    • English, K.1    Ryan, J.M.2    Tobin, L.3    Murphy, M.J.4    Barry, F.P.5    Mahon, B.P.6
  • 26
    • 77955093536 scopus 로고    scopus 로고
    • Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton's Jelly and bone marrow sources
    • Najar, M., G. Raicevic, H. I. Boufker, H. Fayyad Kazan, C. De Bruyn, N. Meuleman, D. Bron, M. Toungouz, and L. Lagneaux. 2010. Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton's Jelly and bone marrow sources. Cell. Immunol. 264: 171-179.
    • (2010) Cell. Immunol. , vol.264 , pp. 171-179
    • Najar, M.1    Raicevic, G.2    Boufker, H.I.3    Fayyad Kazan, H.4    De Bruyn, C.5    Meuleman, N.6    Bron, D.7    Toungouz, M.8    Lagneaux, L.9
  • 27
    • 77951975599 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism
    • Chen, K., D. Wang, W. T. Du, Z. B. Han, H. Ren, Y. Chi, S. G. Yang, D. Zhu, F. Bayard, and Z. C. Han. 2010. Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism. Clin. Immunol. 135: 448-458.
    • (2010) Clin. Immunol. , vol.135 , pp. 448-458
    • Chen, K.1    Wang, D.2    Du, W.T.3    Han, Z.B.4    Ren, H.5    Chi, Y.6    Yang, S.G.7    Zhu, D.8    Bayard, F.9    Han, Z.C.10
  • 29
    • 34249662219 scopus 로고    scopus 로고
    • IFN-gamma and TNF-αlpha differentially regulate immunomodulation by murine mesenchymal stem cells
    • English, K., F. P. Barry, C. P. Field-Corbett, and B. P. Mahon. 2007. IFN-gamma and TNF-αlpha differentially regulate immunomodulation by murine mesenchymal stem cells. Immunol. Lett. 110: 91-100.
    • (2007) Immunol. Lett. , vol.110 , pp. 91-100
    • English, K.1    Barry, F.P.2    Field-Corbett, C.P.3    Mahon, B.P.4
  • 31
    • 0036690151 scopus 로고    scopus 로고
    • Endogenous kynurenines as targets for drug discovery and development
    • Stone, T. W., and L. G. Darlington. 2002. Endogenous kynurenines as targets for drug discovery and development. Nat. Rev. Drug Discov. 1: 609-620.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 609-620
    • Stone, T.W.1    Darlington, L.G.2
  • 32
    • 4644265937 scopus 로고    scopus 로고
    • Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2- overexpressing glioma
    • Akasaki, Y., G. Liu, N. H. Chung, M. Ehtesham, K. L. Black, and J. S. Yu. 2004. Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2- overexpressing glioma. J. Immunol. 173: 4352-4359.
    • (2004) J. Immunol. , vol.173 , pp. 4352-4359
    • Akasaki, Y.1    Liu, G.2    Chung, N.H.3    Ehtesham, M.4    Black, K.L.5    Yu, J.S.6
  • 33
    • 34548804503 scopus 로고    scopus 로고
    • Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma
    • Bergmann, C., L. Strauss, R. Zeidler, S. Lang, and T. L. Whiteside. 2007. Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma. Cancer Res. 67: 8865-8873.
    • (2007) Cancer Res. , vol.67 , pp. 8865-8873
    • Bergmann, C.1    Strauss, L.2    Zeidler, R.3    Lang, S.4    Whiteside, T.L.5
  • 34
    • 74849091357 scopus 로고    scopus 로고
    • Novel role of plasmacytoid dendritic cells in humans: Induction of interleukin-10- producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy
    • Kavousanaki, M., A. Makrigiannakis, D. Boumpas, and P. Verginis. 2010. Novel role of plasmacytoid dendritic cells in humans: induction of interleukin-10- producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy. Arthritis Rheum. 62: 53-63.
    • (2010) Arthritis Rheum. , vol.62 , pp. 53-63
    • Kavousanaki, M.1    Makrigiannakis, A.2    Boumpas, D.3    Verginis, P.4
  • 35
    • 84862536061 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cells prevent transplant arteriosclerosis by enhancing local expression of interleukin-10, interferon-g, and indoleamine 2,3-dioxygenase
    • Jui, H. Y., C. H. Lin, W. T. Hsu, Y. R. Liu, R. B. Hsu, B. L. Chiang, W. Y. Tseng, M. F. Chen, K. K. Wu, and C. M. Lee. 2012. Autologous mesenchymal stem cells prevent transplant arteriosclerosis by enhancing local expression of interleukin-10, interferon-g, and indoleamine 2,3-dioxygenase. Cell Transplant. 21: 971-984.
    • (2012) Cell Transplant. , vol.21 , pp. 971-984
    • Jui, H.Y.1    Lin, C.H.2    Hsu, W.T.3    Liu, Y.R.4    Hsu, R.B.5    Chiang, B.L.6    Tseng, W.Y.7    Chen, M.F.8    Wu, K.K.9    Lee, C.M.10
  • 36
    • 33745622659 scopus 로고    scopus 로고
    • CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: Additional mechanisms of T-cell inhibition
    • von Bergwelt-Baildon, M. S., A. Popov, T. Saric, J. Chemnitz, S. Classen, M. S. Stoffel, F. Fiore, U. Roth, M. Beyer, S. Debey, et al. 2006. CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. Blood 108: 228-237.
    • (2006) Blood , vol.108 , pp. 228-237
    • Von Bergwelt-Baildon, M.S.1    Popov, A.2    Saric, T.3    Chemnitz, J.4    Classen, S.5    Stoffel, M.S.6    Fiore, F.7    Roth, U.8    Beyer, M.9    Debey, S.10
  • 37
    • 84860340144 scopus 로고    scopus 로고
    • Ambivalent effects of dendritic cells displaying prostaglandin E2-induced indoleamine 23-dioxygenase
    • Lanzinger, M., B. Jü rgens, U. Hainz, B. Dillinger, J. Raberger, D. Fuchs, and A. Heitger. 2012. Ambivalent effects of dendritic cells displaying prostaglandin E2-induced indoleamine 2,3-dioxygenase. Eur. J. Immunol. 42: 1117-1128.
    • (2012) Eur J Immunol , vol.42 , pp. 1117-1128
    • Lanzinger, M.1    Jürgens, B.2    Hainz, U.3    Dillinger, B.4    Raberger, J.5    Fuchs, D.6    Heitger, A.7
  • 39
    • 66549102581 scopus 로고    scopus 로고
    • Co-operative action of interleukin-10 and interferon-gamma to regulate dendritic cell functions
    • Yanagawa, Y., K. Iwabuchi, and K. Onoé. 2009. Co-operative action of interleukin-10 and interferon-gamma to regulate dendritic cell functions. Immunology 127: 345-353.
    • (2009) Immunology , vol.127 , pp. 345-353
    • Yanagawa, Y.1    Iwabuchi, K.2    Onoé., K.3
  • 40
    • 27144476792 scopus 로고    scopus 로고
    • A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation
    • Braun, D., R. S. Longman, and M. L. Albert. 2005. A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation. Blood 106: 2375-2381.
    • (2005) Blood , vol.106 , pp. 2375-2381
    • Braun, D.1    Longman, R.S.2    Albert, M.L.3
  • 41
    • 33746906695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: Role of IDO
    • Basu, G. D., T. L. Tinder, J. M. Bradley, T. Tu, C. L. Hattrup, B. A. Pockaj, and P. Mukherjee. 2006. Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO. J. Immunol. 177: 2391-2402.
    • (2006) J. Immunol. , vol.177 , pp. 2391-2402
    • Basu, G.D.1    Tinder, T.L.2    Bradley, J.M.3    Tu, T.4    Hattrup, C.L.5    Pockaj, B.A.6    Mukherjee, P.7
  • 42
    • 77953229722 scopus 로고    scopus 로고
    • COX-2 and PGE2 signaling is essential for the regulation of IDO expression by curcumin in murine bone marrow-derived dendritic cells
    • Jung, I. D., Y. I. Jeong, C. M. Lee, K. T. Noh, S. K. Jeong, S. H. Chun, O. H. Choi, W. S. Park, J. Han, Y. K. Shin, et al. 2010. COX-2 and PGE2 signaling is essential for the regulation of IDO expression by curcumin in murine bone marrow-derived dendritic cells. Int. Immunopharmacol. 10: 760-768.
    • (2010) Int. Immunopharmacol. , vol.10 , pp. 760-768
    • Jung, I.D.1    Jeong, Y.I.2    Lee, C.M.3    Noh, K.T.4    Jeong, S.K.5    Chun, S.H.6    Choi, O.H.7    Park, W.S.8    Han, J.9    Shin, Y.K.10
  • 44
    • 0026616920 scopus 로고
    • The prostaglandin E1 analogue, misoprostol, regulates inflammatory cytokines and immune functions in vitro like the natural prostaglandins E1, E2 and E3
    • Haynes, D. R., M. W. Whitehouse, and B. Vernon-Roberts. 1992. The prostaglandin E1 analogue, misoprostol, regulates inflammatory cytokines and immune functions in vitro like the natural prostaglandins E1, E2 and E3. Immunology 76: 251-257.
    • (1992) Immunology , vol.76 , pp. 251-257
    • Haynes, D.R.1    Whitehouse, M.W.2    Vernon-Roberts, B.3
  • 45
    • 80052401660 scopus 로고    scopus 로고
    • Inflammation-restraining effects of prostaglandin E2 on natural killer-dendritic cell (NK-DC) interaction are imprinted during DC maturation
    • Van Elssen, C. H., J. Vanderlocht, T. Oth, B. L. Senden-Gijsbers, W. T. Germeraad, and G. M. Bos. 2011. Inflammation-restraining effects of prostaglandin E2 on natural killer-dendritic cell (NK-DC) interaction are imprinted during DC maturation. Blood 118: 2473-2482.
    • (2011) Blood , vol.118 , pp. 2473-2482
    • Van Elssen, C.H.1    Vanderlocht, J.2    Oth, T.3    Senden-Gijsbers, B.L.4    Germeraad, W.T.5    Bos, G.M.6
  • 46
    • 0025236286 scopus 로고
    • Prevention of acute graft rejection by the prostaglandin E1 analogue misoprostol in renal-transplant recipients treated with cyclosporine and prednisone
    • Moran, M., M. F. Mozes, M. S. Maddux, S. Veremis, C. Bartkus, B. Ketel, R. Pollak, C. Wallemark, and O. Jonasson. 1990. Prevention of acute graft rejection by the prostaglandin E1 analogue misoprostol in renal-transplant recipients treated with cyclosporine and prednisone. N. Engl. J. Med. 322: 1183-1188.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1183-1188
    • Moran, M.1    Mozes, M.F.2    Maddux, M.S.3    Veremis, S.4    Bartkus, C.5    Ketel, B.6    Pollak, R.7    Wallemark, C.8    Jonasson, O.9
  • 47
    • 84855361145 scopus 로고    scopus 로고
    • Regulation of immune responses by prostaglandin E2
    • Kalinski, P. 2012. Regulation of immune responses by prostaglandin E2. J. Immunol. 188: 21-28.
    • (2012) J. Immunol. , vol.188 , pp. 21-28
    • Kalinski, P.1
  • 48
    • 33746368487 scopus 로고    scopus 로고
    • Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells
    • Battaglia, M., A. Stabilini, E. Draghici, B. Migliavacca, S. Gregori, E. Bonifacio, and M. G. Roncarolo. 2006. Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells. Diabetes 55: 1571-1580.
    • (2006) Diabetes , vol.55 , pp. 1571-1580
    • Battaglia, M.1    Stabilini, A.2    Draghici, E.3    Migliavacca, B.4    Gregori, S.5    Bonifacio, E.6    Roncarolo, M.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.