IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering

Biotechnology and Bioengineering

Volumn 110, Issue 4, 2013, Pages 1153-1163

  Contie, Mathias ^a,b   Leger, Olivier ^b   Fouque, Nicolas ^b   Poitevin, Yves ^b   Kosco Vilbois, Marie ^b   Mermod, Nicolas ^a   Elson, Greg ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b NOVIMMUNE SA   (Switzerland)

Author keywords

Cell line generation; CHO; IL 17F; Recombinant protein production

Indexed keywords

CELL LINES; CHO; CHO CELL; CO-EXPRESSION; CRITICAL STEPS; GENERATION PROCESS; GROWTH CHARACTERISTIC; HIGH PRODUCTIVITY; IL-17F; INNOVATIVE ENGINEERING; MAMMALIAN CELLS; MANUFACTURING PROCESS; PROCESS EFFICIENCY; PRODUCTION CELLS; PRODUCTION OF; RATE OF PRODUCTIONS; RECOMBINANT PROTEIN PRODUCTIONS; SELECTION SYSTEMS; SUBCLONING; THERAPEUTIC PROTEIN; TIME FRAME; TRANSGENE EXPRESSION;

CELL ENGINEERING; INNOVATION; PRODUCTIVITY; RECOMBINANT PROTEINS;

CELL CULTURE;

INTERLEUKIN 17F; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL CLONING; CELL ENGINEERING; CELL GROWTH; CELL SELECTION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; NONHUMAN; PRODUCTIVITY; PROTEIN EXPRESSION; TRANSGENE;

ANIMALS; CELL DIVISION; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETIC VECTORS; HUMANS; INTERLEUKIN-17; RECOMBINANT PROTEINS;

MAMMALIA;

EID: 84874195852     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24763     Document Type: Article

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