Strain Dependent Variation of Immune Responses to A. fumigatus: Definition of Pathogenic Species

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Rizzetto, Lisa ^a   Giovannini, Gloria ^b   Bromley, Michael ^c,d   Bowyer, Paul ^c,d   Romani, Luigina ^b   Cavalieri, Duccio ^a,e  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e Innovation and Research Center   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FUNGAL STRAIN; FUNGAL VIRULENCE; FUNGUS ISOLATION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOREACTIVITY; MOUSE; NONHUMAN; STRAIN DIFFERENCE;

ANIMALS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CYTOKINES; DENDRITIC CELLS; HUMANS; INFLAMMATION; MELANINS; MICE; MUTATION; VIRULENCE;

EID: 84874165058     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056651     Document Type: Article

References (45)

1. Latge JP, (2010) Tasting the fungal cell wall. Cell Microbiol 12: 863-872.
2. Bourgeois C, Majer O, Frohner IE, Tierney L, Kuchler K, (2010) Fungal attacks on mammalian hosts: pathogen elimination requires sensing and tasting. Curr Opin Microbiol 13: 401-408.
3. van de Veerdonk FL, Marijnissen RJ, Kullberg BJ, Koenen HJ, Cheng SC, et al. (2009) The macrophage mannose receptor induces IL-17 in response to Candida albicans. Cell Host Microbe 5: 329-340.
4. Kankkunen P, Teirila L, Rintahaka J, Alenius H, Wolff H, et al. (2010) (1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages. J Immunol 184: 6335-6342.
5. Esteban A, Popp MW, Vyas VK, Strijbis K, Ploegh HL, et al. (2011) Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages. Proc Natl Acad Sci U S A 108: 14270-14275.
6. Chai LY, Vonk AG, Kullberg BJ, Verweij PE, Verschueren I, et al. (2011) Aspergillus fumigatus cell wall components differentially modulate host TLR2 and TLR4 responses. Microbes Infect 13: 151-159.
7. Sorrell TC, Chen SC, (2009) Fungal-derived immune modulating molecules. Adv Exp Med Biol 666: 108-120.
8. Goodridge HS, Wolf AJ, Underhill DM, (2009) Beta-glucan recognition by the innate immune system. Immunol Rev 230: 38-50.
9. Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, et al. (2009) Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect Immun 77: 1774-1781.
10. Rizzetto L, Kuka M, De Filippo C, Cambi A, Netea MG, et al. (2010) Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism. J Immunol 184: 4258-4268.
11. Drummond RA, Brown GD, (2011) The role of Dectin-1 in the host defence against fungal infections. Curr Opin Microbiol 14: 392-399.
12. Cramer RA, Rivera A, Hohl TM, (2011) Immune responses against Aspergillus fumigatus: what have we learned? Curr Opin Infect Dis 24: 315-322.
13. Luther K, Torosantucci A, Brakhage AA, Heesemann J, Ebel F, (2007) Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2. Cell Microbiol 9: 368-381.
14. Chai LY, Kullberg BJ, Vonk AG, Warris A, Cambi A, et al. (2009) Modulation of Toll-like receptor 2 (TLR2) and TLR4 responses by Aspergillus fumigatus. Infect Immun 77: 2184-2192.
15. Ramaprakash H, Ito T, Standiford TJ, Kunkel SL, Hogaboam CM, (2009) Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice. Infect Immun 77: 108-119.
16. Bourgeois C, Majer O, Frohner I, Kuchler K, (2009) In vitro systems for studying the interaction of fungal pathogens with primary cells from the mammalian innate immune system. Methods Mol Biol 470: 125-139.
17. van de Veerdonk FL, Kullberg BJ, van der Meer JW, Gow NA, Netea MG, (2008) Host-microbe interactions: innate pattern recognition of fungal pathogens. Curr Opin Microbiol 11: 305-312.
18. Chai LY, Netea MG, Sugui J, Vonk AG, van de Sande WW, et al. (2010) Aspergillus fumigatus conidial melanin modulates host cytokine response. Immunobiology 215: 915-920.
19. Karkowska-Kuleta J, Rapala-Kozik M, Kozik A, (2009) Fungi pathogenic to humans: molecular bases of virulence of Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. Acta Biochim Pol 56: 211-224.
20. McCormick A, Loeffler J, Ebel F, (2010) Aspergillus fumigatus: contours of an opportunistic human pathogen. Cell Microbiol 12: 1535-1543.
21. Kekkonen RA, Lummela N, Karjalainen H, Latvala S, Tynkkynen S, et al. (2008) Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. World J Gastroenterol 14: 2029-2036.
22. Foligne B, Nutten S, Grangette C, Dennin V, Goudercourt D, et al. (2007) Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria. World J Gastroenterol 13: 236-243.
23. Foligne B, Deutsch SM, Breton J, Cousin FJ, Dewulf J, et al. (2010) Promising immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo. Appl Environ Microbiol 76: 8259-8264.
24. Foligne B, Dewulf J, Vandekerckove P, Pignede G, Pot B, (2010) Probiotic yeasts: anti-inflammatory potential of various non-pathogenic strains in experimental colitis in mice. World J Gastroenterol 16: 2134-2145.
25. Clemons KV, Stevens DA, (2005) The contribution of animal models of aspergillosis to understanding pathogenesis, therapy and virulence. Med Mycol 43Suppl 1: S101-110.
26. Szewczyk E, Nayak T, Oakley CE, Edgerton H, Xiong Y, et al. (2006) Fusion PCR and gene targeting in Aspergillus nidulans. Nat Protoc 1: 3111-3120.
27. Punt PJ, Oliver RP, Dingemanse MA, Pouwels PH, van den Hondel CA, (1987) Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli. Gene 56: 117-124.
28. Sallusto F, Lanzavecchia A, (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 179: 1109-1118.
29. Bonifazi P, D'Angelo C, Zagarella S, Zelante T, Bozza S, et al. (2010) Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis. Mucosal Immunol 3: 193-205.
30. Medzhitov R, Janeway CA Jr, (2002) Decoding the patterns of self and nonself by the innate immune system. Science 296: 298-300.
31. Romani L, (2011) Immunity to fungal infections. Nat Rev Immunol 11: 275-288.
32. Peran L, Camuesco D, Comalada M, Nieto A, Concha A, et al. (2005) Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis. World J Gastroenterol 11: 5185-5192.
33. Romani L, Puccetti P, (2006) Protective tolerance to fungi: the role of IL-10 and tryptophan catabolism. Trends Microbiol 14: 183-189.
34. De Luca A, Iannitti RG, Bozza S, Beau R, Casagrande A, et al. (2012) CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease. J Clin Invest 122: 1816-1831.
35. Romani L, Fallarino F, De Luca A, Montagnoli C, D'Angelo C, et al. (2008) Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature 451: 211-215.
36. D'Enfert C, Diaquin M, Delit A, Wuscher N, Debeaupuis JP, et al. (1996) Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus. Infect Immun 64: 4401-4405.
37. Aimanianda V, Bayry J, Bozza S, Kniemeyer O, Perruccio K, et al. (2009) Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460: 1117-1121.
38. Carvalho A, Cunha C, Romani L, (2011) Immunity and tolerance to infections in experimental hematopoietic transplantation. Best Pract Res Clin Haematol 24: 435-442.
39. Richardson MD, (2005) Changing patterns and trends in systemic fungal infections. J Antimicrob Chemother 56Suppl 1: i5-i11.
40. Upton A, Kirby KA, Carpenter P, Boeckh M, Marr KA, (2007) Invasive aspergillosis following hematopoietic cell transplantation: outcomes and prognostic factors associated with mortality. Clin Infect Dis 44: 531-540.
41. Fedorova ND, Khaldi N, Joardar VS, Maiti R, Amedeo P, et al. (2008) Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus. PLoS Genet 4: e1000046.
42. Ene IV, Cheng SC, Netea MG, Brown AJ (2012) Growth of Candida albicans cells on the physiologically relevant carbon source, lactate, affects their recognition and phagocytosis by immune cells. Infect Immun.
43. Ene IV, Adya AK, Wehmeier S, Brand AC, MacCallum DM, et al. (2012) Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen. Cell Microbiol 14: 1319-1335.
44. Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, et al. (2005) Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 438: 1151-1156.
45. Beauvais A, Monod M, Wyniger J, Debeaupuis JP, Grouzmann E, et al. (1997) Dipeptidyl-peptidase IV secreted by Aspergillus fumigatus, a fungus pathogenic to humans. Infect Immun 65: 3042-3047.