In vitro systems for studying the interaction of fungal pathogens with primary cells from the mammalian innate immune system

Methods in Molecular Biology

Volumn 470, Issue , 2008, Pages 125-139

  Bourgeois, Christelle ^a   Majer, Olivia ^a   Frohner, Ingrid ^a   Kuchler, Karl ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Bone marrow derived macrophages; Candida spp; Cell signaling; Cytokines; Host pathogen interaction; MAPK; Myeloid dendritic cells; Primary cell culture

Indexed keywords

CANDIDA; HUMAN IMMUNODEFICIENCY VIRUS; MAMMALIA;

EID: 62549153099     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-204-5_11     Document Type: Article

References (19)

1. Roeder A, Kirschning CJ, Rupee RA, Schaller M, Korting HC. Toll-like receptors and innate antifungal responses. Trends Microbiol 2004;12:44-9.
2. Netea MG, Van der Graaf C, Van der Meer JW, Kullberg BJ. Recognition of fungal pathogens by Toll-like receptors: Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system. Eur J Clin Microbiol Infect Dis 2004;23:672-6.
3. Mencacci A, Cenci E, Del Sero G, et al. Defective co-stimulation and impaired Thl development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans. Int Immunol 1998;10:37-48.
4. Vazquez-Torres A, Jones-Carson J, Wagner RD, Warner T, Balish E. Early resistance of interleukin-10 knock-out mice to acute systemic candidiasis. Infect Immun 1999;67:670-4.
5. Farah CS, Hu Y, Riminton S, Ashman RB. Distinct roles for interleukin-12p40 and tumour necrosis factor in resistance to oral candidiasis defined by gene-targeting. Oral Microbiol Immunol 2006;21: 252-5.
6. Vonk AG, Netea MG, van Krieken JH, van der Meer JW, Kullberg BJ. Delayed clearance of intraabdominal abscesses caused by Candida albicans in tumor necrosis factor-alpha- and lymphotoxinalpha-deficient mice. J Infect Dis 2002;186:1815-22.
7. Ibata-Ombetta S, Jouault T, Trinel PA, Poulain D. Role of extracellular signalregulated protein kinase cascade in macrophage killing of Candida albicans. J Leukoc Biol 2001;70:149-54.
8. Zhong B, Jiang K, Gilvary DL, et al. Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens. Blood 2003;101:3240-8.
9. Choi JH, Choi EK, Park SJ, et al. Impairment of p38 MAPK-mediated cytosolic phospholipase A(2) activation in the kidneys is associated with pathogenicity of Candida albicans. Immunology 2007; 120:173-81.
10. Zal T, Volkmann A, Stockinger B. Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. J Exp Med 1994;180: 2089-99.
11. Gillum AM, Tsay EY, Kirsch DR. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol Gen Genet 1984;198:179-82.
12. Hull CM, Johnson AD. Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science 1999;285:1271-5.
13. Kovarik P, Stoiber D, Novy M, Decker T. Statl combines signals derived from IFN-gamma and LPS receptors during macrophage activation. EMBO J 1998;17: 3660-8.
14. Overbergh L, Giulietti A, Valckx D, Decallonne R, Bouillon R, Mathieu C. The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression. J Biomol Tech 2003;14:33-43.
15. Pattyn F, Speleman F, De Paepe A, Vandesompele J. RTPrimerDB: the Real-Time PCR primer and probe data-base. Nucl Acids Res 2003;31:122-3.
16. Pattyn F, Robbrecht P, De Paepe A, Speleman F, Vandesompele J. RTPrimerDB: the real-time PCR primer and probe data-base, major update 2006. Nucl Acids Res 2006;34:D684-8.
17. 2+, and adherence. J Cell Physiol 1983;117: 189-94.
18. Inaba K, Inaba M, Romani N, et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 1992; 176:1693-702.
19. Herth W Calcofluor white and Congo red inhibit chitin microfibril assembly of Poterioochromonas: evidence for a gap between polymerization and microfibril formation. J Cell Biol 1980;87:442-50.