Human biodistribution and dosimetry of 18F-JNJ42259152, a radioligand for phosphodiesterase 10A imaging

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 40, Issue 2, 2013, Pages 254-261

  Van Laere, Koen ^a   Ahmad, Rawaha U ^a   Hudyana, Hendra ^a   Celen, Sofie ^c   Dubois, Kristof ^b   Schmidt, Mark E ^b   Bormans, Guy ^c   Koole, Michel ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

18F JNJ42259152; Biodistribution; Brain kinetics; Dosimetry; PET; Phosphodiesterase 10A

Indexed keywords

18F JNJ 42259152; 2 [[4 [1 (2 FLUOROETHYL) 4 (4 PYRIDINYL) 1 PYRAZOL 3 YL]PHENOXY]METHYL] 3,5 DIMETHYL PYRIDINE F 18; PHOSPHODIESTERASE; PHOSPHODIESTERASE 10A; PYRIDINE DERIVATIVE; RADIOLIGAND; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DEFLUORINATION; DOSIMETRY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG SAFETY; HUMAN; HUMAN EXPERIMENT; IMAGE RECONSTRUCTION; KIDNEY CLEARANCE; MALE; MOLECULAR IMAGING; NEUROIMAGING; NORMAL HUMAN; RADIATION ABSORPTION; RADIATION DOSE DISTRIBUTION; WHOLE BODY PET;

ADULT; AGED; BRAIN; FLUORINE RADIOISOTOPES; HUMANS; HYDROLYSIS; KINETICS; LIGANDS; MALE; MIDDLE AGED; PHOSPHORIC DIESTER HYDROLASES; POSITRON-EMISSION TOMOGRAPHY; PYRAZOLES; PYRIDINES; RADIOMETRY; RADIOPHARMACEUTICALS; TIME FACTORS; WHOLE BODY IMAGING;

EID: 84874109233     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-012-2270-1     Document Type: Article

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