Inhibitory effects of alkaline extract of Citrus reticulata on pulmonary fibrosis

Journal of Ethnopharmacology

Volumn 146, Issue 1, 2013, Pages 372-378

  Li, Jian Xin ^a,b   Zhou, Xian Mei ^a   Wen, Gao Yan ^a   Zhao, Yang ^a   Liu, Yu Mei ^b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Citrus alkaline extract; Citrus reticulata; Inhibitory effects; Mechanism; Pulmonary fibrosis

Indexed keywords

BLEOMYCIN; CITRUS FRUIT EXTRACT; CITRUS RETICULATA EXTRACT; GELATINASE B; LACTATE DEHYDROGENASE; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG FIBROSIS; MALE; MANDARIN; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT GAIN; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLEOMYCIN; CELL LINE; CELL PROLIFERATION; CITRUS; HUMANS; HYDROXYPROLINE; L-LACTATE DEHYDROGENASE; MALE; MATRIX METALLOPROTEINASE 9; PHYTOTHERAPY; PLANT EXTRACTS; PULMONARY FIBROSIS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TUMOR NECROSIS FACTOR-ALPHA;

CITRUS; CITRUS RETICULATA; RATTUS;

EID: 84874107042     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.01.006     Document Type: Article

References (28)

1. A. Andersson-Sjöland, C.G. de Alba, K. Nihlberg, C. Becerril, R. Ramírez, A. Pardo, G. Westergren-Thorsson, and M. Selman Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis International Journal of Biochemistry & Cell Biology 40 2008 2129 2140
2. K.M. Antoniou, A. Pataka, D. Bouros, and N.M. Slafakas Pathogenetic pathways and novel pharmaco therapeutic targets in idiopathic pulmonary fibrosis Pulmonary Pharmacology & Therapeutics 20 2007 453 461
3. K. Ask, R. Labiris, L. Farkas, A. Moeller, A. Froese, T. Farncombe, G.B. McClelland, M. Inman, J. Gauldie, and M.R.J. Kolb Comparison between conventional and clinical assessment of experimental lung fibrosis Journal of Translational Medicine 6 2008 1 10
4. S. Cabrera, M. Gaxiola, J.L. Arreola, R. Ramírez, P. Jara, J. D'Armiento, T. Richards, M. Selman, and A. Pardo Overexpression of MMP-9 in macrophages attenuates pulmonary fibrosis induced by bleomycin International Journal of Biochemistry & Cell Biology 39 2007 2324 2338
5. China Pharmacopoeia Committee Chinese Pharmacopeia 2010 Chemical Industry Press Beijing, China
6. O. Hilberg, U. Simonsen, R. du Bois, and E. Bendstrup Pirfenidone: significant treatment effects in idiopathic pulmonary fibrosis The Clinical Respiratory Journal 6 2012 131 143
7. E. Honda, and H. Munakata Purification and characterization of decorin from the culture media of MRC-5 cells International Journal of Biochemistry & Cell Biology 36 2004 1635 1644
8. R.C. Klingsberg, S.E. Mutsaers, and J.A. Lasky Current clinical trials for the treatment of idiopathic pulmonary fibrosis Respirology 15 2010 19 31
9. J.H.S. Kuo, M.S. Jan, C.H. Chang, H.W. Chiu, and C.T. Li Cytotoxicity characterization of catanionic vesicles in RAW 264.7 murine macrophage-like cells Colloids and Surfaces B: Biointerfaces 41 2005 189 196
10. J. Londono-Londono, V.R. de Lima, O. Lara, A. Gil, T.B.C. Pasa, G.J. Arango, and J.R.R. Pineda Clean recovery of antioxidant flavonoids from citrus peel: optimizing an aqueous ultrasound-assisted extraction method Food Chemistry 119 2010 81 87
11. D.K. Madtes, A.L. Elston, L.A. Kaback, and J.G. Clark Selective induction of tissue inhibitor of metalloproteinase-1 in bleomycin-induced pulmonary fibrosis American Journal of Respiratory Cell and Molecular Biology 24 2001 599 607
12. B. Manoury, S. Nénan, I. Guénon, V. Lagente., and E. Boichot Influence of early neutrophil depletion on MMPs/TIMP-1 balance in bleomycin-induced lung fibrosis International Journal of Immunopharmacology 7 2007 900 911
13. E.E. McGrath, A. Lawrie, H.M. Marriott, P. Mercer, S.S. Cross, N. Arnold, V. Singleton, A.A.R. Thompson, S.R. Walmsley, S.A. Renshaw, I. Sabroe, R.C. Chambers, D.H. Dockrell, and M.K.B. Whyte Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis Thorax 67 2012 796 803
14. S. McKeown, A.G. Richter, C. O'Kane, D.F. McAuley, and D.R. Thickett MMP expression and abnormal lung permeability are important determinants of outcome in IPF European Respiratory Journal 33 2009 77 84
15. A. Moeller, K. Ask, D. Warburton, J. Gauldie, and M. Kolb The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? International Journal of Biochemistry & Cell Biology 40 2008 362 382
16. A. Moeller, S.E. Gilpin, K. Ask, G. Cox, D. Cook, J. Gauldie, P.J. Margetts, L. Farkas, J. Dobranowski, C. Boylan, P.M. O'Byrne, R.M. Strieter, and M. Kolb Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis American Journal of Respiratory and Critical Care Medicine 179 2009 588 594
17. G. Moghaddam, S.A. Ebrahimi, N. Rahbar-Roshandel, and A. Foroumadi Antiproliferative activity of flavonoids: influence of the sequential methoxylation state of the flavonoid structure Phytotherapy Research 26 2012 1023 1028
18. B.B. Moore, and C.M. Hogaboam Murine models of pulmonary fibrosis American Journal of Physiology - Lung Cellular and Molecular Physiology 294 2008 L152 L160
19. L.A. Murray Commonalities between the pro-fibrotic mechanisms in COPD and IPF Pulmonary Pharmacology & Therapeutics 25 2012 276 280
20. T. Ohkawa, N. Ueki, T. Taguchi, Y. Shindo, M. Adachi, Y. Amuro, T. Hada, and K. Higashino Stimulation of hyaluronan synthesis by tumor necrosis factor-α is mediated by the p50/p65 NF-κB complex in MRC-5 myofibroblasts Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1448 1999 416 424
21. A. Pardo, M. Selman, and N. Naftali Kaminski Approaching the degradome in idiopathic pulmonary fibrosis International Journal of Biochemistry & Cell Biology 40 2008 1141 1155
22. G. Raghu, H.R. Collard, J.J. Egan, F.J. Martinez, J. Behr, K.K. Brown, T.V. Colby, J.F. Cordier, K.R. Flaherty, J.A. Lasky, D.A. Lynch, J.H. Ryu, J.J. Swigris, A.U. Wells, J. Ancochea, D. Bouros, C. Carvalho, U. Costabel, M. Ebina, D.M. Hansell, T. Johkoh, D.S. Kim, T.E. King Jr., Y. Kondoh, J. Myers, N.L. Müller, A.G. Nicholson, L. Richeldi, M. Selman, R.F. Dudden, B.S. Griss, S.L. Protzko, H.J. Schünemann on behalf of the ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis An official ATS/ ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management American Journal of Respiratory and Critical Care Medicine 183 2011 788 824
23. M. Selman, V. Ruiz, S. Cabrera, L. Segura, R. Ramirez, R. Barrios, and A. Pardo TIMP-1,-2,-3, and -4 in idiopathic pulmonary fibrosis - a prevailing nondegradative lung microenvironment? American Journal of Physiology - Lung Cellular and Molecular Physiology 279 2000 L562 L574
24. S.V. Szapiel, N.A. Elson, J.D. Fulmer, G.W. Hunninghake, and R.G. Crystal Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse American Review of Respiratory Disease 120 1979 893 899
25. S.M. Vieira, K.H. Theodoro, and M.B.A. Glória Profile and levels of bioactive amines in orange juice and orange soft drink Food Chemistry 100 2007 895 903
26. R. Vij, and I. Noth Peripheral blood biomarkers in idiopathic pulmonary fibrosis Translational Research 159 2012 218 227
27. X.M. Zhou, M.M. Huang, C.C. He, and J.X. Li Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis Journal of Ethnopharmacology 126 2009 143 148
28. X.M. Zhou, G.C. Zhang, J.X. Li, and J. Hou Inhibitory effects of Hu-qi-yin on the bleomycin-induced pulmonary fibrosis in rats Journal of Ethnopharmacology 111 2007 255 264