Upregulation of TRIM5α gene expression after liveattenuated simian immunodeficiency virus vaccination in Mauritian cynomolgus macaques, but TRIM5α genotype has no impact on virus acquisition or vaccination outcome

Journal of General Virology

Volumn 94, Issue PART3, 2013, Pages 606-611

  Mattiuzzo, Giada ^a   Rose, Nicola J ^a   Almond, Neil ^a   Towers, Greg J ^b   Berry, Neil ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SIMIAN IMMUNODEFICIENCY VIRUS VACCINE; TRIPARTITE MOTIF PROTEIN 5;

ARTICLE; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; LYMPHOID TISSUE; MACACA; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; UPREGULATION; VACCINATION; VIRUS REPLICATION;

ANIMALS; CARRIER PROTEINS; GENE EXPRESSION REGULATION; GENOTYPE; MACACA FASCICULARIS; MOLECULAR SEQUENCE DATA; RNA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SPECIES SPECIFICITY; TIME FACTORS; VIRAL VACCINES; VIRUS REPLICATION;

EID: 84874101858     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.047795-0     Document Type: Article

References (29)

1. Almond, N., Kent, K., Stott, E. J., Cranage, M., Rud, E., Clarke, B. & Rud, E. (1995). Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells. Lancet 345, 1342-1344.
2. Almond, N., Rose, J., Sangster, R., Silvera, P., Stebbings, R., Walker, B. & Stott, E. J. (1997). Mechanisms of protection induced by attenuated simian immunodeficiency virus. I. Protection cannot be transferred with immune serum. J Gen Virol 78, 1919-1922.
3. Berry, N., Stebbings, R., Ferguson, D., Ham, C., Alden, J., Brown, S., Jenkins, A., Lines, J., Duffy, L. &other authors (2008). Resistance to superinfection by a vigorously replicating, uncloned stock of simian immunodeficiency virus (SIVmac251) stimulates replication of a live attenuated virus vaccine (SIVmacC8). J Gen Virol 89, 2240-2251.
4. Berry, N., Ham, C., Mee, E. T., Rose, N. J., Mattiuzzo, G., Jenkins, A., Page, M., Elsley, W., Robinson, M. &other authors (2011). Early potent protection against heterologous SIVsmE660 challenge following live attenuated SIV vaccination in Mauritian cynomolgus macaques. PLoS ONE 6, e23092.
5. Berry, N. J., Marzetta, F., Towers, G. J. & Rose, N. J. (2012). Diversity of TRIM5α and TRIMCyp sequences in cynomolgus macaques from different geographical origins. Immunogenetics 64, 267-278.
6. Daniel, M. D., Kirchhoff, F., Czajak, S. C., Sehgal, P. K. & Desrosiers, R. C. (1992). Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258, 1938-1941.
7. de Groot, N. G., Heijmans, C. M., Koopman, G., Verschoor, E. J., Bogers, W. M. & Bontrop, R. E. (2011). TRIM5 allelic polymorphism in macaque species/populations of different geographic origins: its impact on SIV vaccine studies. Tissue Antigens 78, 256-262.
8. Dietrich, E. A., Brennan, G., Ferguson, B., Wiseman, R. W., O'Connor, D. & Hu, S. L. (2011). Variable prevalence and functional diversity of the antiretroviral restriction factor TRIMCyp in Macaca fascicularis. J Virol 85, 9956-9963.
9. Griffin, S. D., Allen, J. F. & Lever, A. M. (2001). The major human immunodeficiency virus type 2 (HIV-2) packaging signal is present on all HIV-2 RNA species: cotranslational RNA encapsidation and limitation of Gag protein confer specificity. J Virol 75, 12058-12069.
10. Kirmaier, A., Wu, F., Newman, R. M., Hall, L. R., Morgan, J. S., O'Connor, S., Marx, P. A., Meythaler, M., Goldstein, S. &other authors (2010). TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species. PLoS Biol 8, e1000462.
11. + T cells. Retrovirology 8, 8.
12. Lim, S. Y., Rogers, T., Chan, T., Whitney, J. B., Kim, J., Sodroski, J. & Letvin, N. L. (2010). TRIM5α modulates immunodeficiency virus control in rhesus monkeys. PLoS Pathog 6, e1000738.
13. Mee, E. T., Berry, N., Ham, C., Sauermann, U., Maggiorella, M. T., Martinon, F., Verschoor, E. J., Heeney, J. L., Le Grand, R. &other authors (2009). Mhc haplotype H6 is associated with sustained control of SIVmac251 infection in Mauritian cynomolgus macaques. Immunogenetics 61, 327-339.
14. Muhl, T., Krawczak, M., Ten Haaft, P., Hunsmann, G. & Sauermann, U. (2002). MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys. J Immunol 169, 3438-3446.
15. Mußil, B., Sauermann, U., Motzkus, D., Stahl-Hennig, C. & Sopper, S. (2011). Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys. Retrovirology 8, 77.
16. Nègre, D., Mangeot, P. E., Duisit, G., Blanchard, S., Vidalain, P. O., Leissner, P., Winter, A. J., Rabourdin-Combe, C., Mehtali, M. &other authors (2000). Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells. Gene Ther 7, 1613-1623.
17. Pertel, T., Hausmann, S., Morger, D., Zuger, S., Guerra, J., Lascano, J., Reinhard, C., Santoni, F. A., Uchil, P. D. &other authors (2011). TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 472, 361-365.
18. Rud, E. W., Cranage, M., Yon, J., Quirk, J., Ogilvie, L., Cook, N., Webster, S., Dennis, M. & Clarke, B. E. (1994). Molecular and biological characterization of simian immunodeficiency virus macaque strain 32H proviral clones containing nef size variants. J Gen Virol 75, 529-543.
19. Saito, A., Kono, K., Nomaguchi, M., Yasutomi, Y., Adachi, A., Shioda, T., Akari, H. & Nakayama, E. E. (2012). Geographical, genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis). J Gen Virol 93, 594-602.
20. Stebbings, R., Berry, N., Stott, J., Hull, R., Walker, B., Lines, J., Elsley, W., Brown, S., Wade-Evans, A. &other authors (2004). Vaccination with live attenuated simian immunodeficiency virus for 21 days protects against superinfection. Virology 330, 249-260.
21. + lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus. J Virol 79, 12264-12272.
22. Stremlau, M., Owens, C. M., Perron, M. J., Kiessling, M., Autissier, P. & Sodroski, J. (2004). The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys. Nature 427, 848-853.
23. Tosi, A. J. & Coke, C. S. (2007). Comparative phylogenetics offer new insights into the biogeographic history of Macaca fascicularis and the origin of the Mauritian macaques. Mol Phylogenet Evol 42, 498-504.
24. Wilson, S. J., Webb, B. L., Maplanka, C., Newman, R. M., Verschoor, E. J., Heeney, J. L. & Towers, G. J. (2008). Rhesus macaque TRIM5 alleles have divergent antiretroviral specificities. J Virol 82, 7243-7247.
25. Wyand, M. S., Manson, K., Montefiori, D. C., Lifson, J. D., Johnson, R. P. & Desrosiers, R. C. (1999). Protection by live, attenuated simian immunodeficiency virus against heterologous challenge. J Virol 73, 8356-8363.
26. Yap, M. W., Nisole, S., Lynch, C. & Stoye, J. P. (2004). TRIM5α protein restricts both HIV-1 and murine leukemia virus. Proc Natl Acad Sci U S A101,10786-10791.
27. Ylinen, L. M., Price, A. J., Rasaiyaah, J., Hué, S., Rose, N. J., Marzetta, F., James, L. C. & Towers, G. J. (2010). Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity. PLoS Pathog 6, e1001062.
28. Zhang, F., Hatziioannou, T., Perez-Caballero, D., Derse, D. & Bieniasz, P. D. (2006). Antiretroviral potential of human tripartite motif-5 and related proteins. Virology 353, 396-409.
29. Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L. & Trono, D. (1997). Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 15, 871-875.