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Volumn 41, Issue 3, 2013, Pages 554-561

Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver diseases

Author keywords

[No Author keywords available]

Indexed keywords

3' PHOSPHOADENOSINE 5' PHOSPHOSULFATE SYNTHASE 1; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2A3; GLUCURONOSYLTRANSFERASE 2B10; GLUCURONOSYLTRANSFERASE 2B15; GLUCURONOSYLTRANSFERASE 2B28; GLUCURONOSYLTRANSFERASE 3A1; MESSENGER RNA; PARACETAMOL; SULFOTRANSFERASE; SULFOTRANSFERASE 1A1; SULFOTRANSFERASE 1C4; SULFOTRANSFERASE 2B1; SULFOTRANSFERASE 4A1; UNCLASSIFIED DRUG;

EID: 84874094715     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.048439     Document Type: Article
Times cited : (104)

References (38)
  • 1
    • 0036293451 scopus 로고    scopus 로고
    • Catecholestrogen sulfation: Possible role in carcinogenesis
    • Adjei AA and Weinshilboum RM (2002) Catecholestrogen sulfation: possible role in carcinogenesis. Biochem Biophys Res Commun 292:402-408.
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 402-408
    • Adjei, A.A.1    Weinshilboum, R.M.2
  • 2
    • 33144485957 scopus 로고    scopus 로고
    • Regulation of drug-metabolizing enzymes and transporters in inflammation
    • Aitken AE, Richardson TA, and Morgan ET (2006) Regulation of drug-metabolizing enzymes and transporters in inflammation. Annu Rev Pharmacol Toxicol 46:123-149.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 123-149
    • Aitken, A.E.1    Richardson, T.A.2    Morgan, E.T.3
  • 3
    • 67649723378 scopus 로고    scopus 로고
    • New diagnostic and treatment approaches in non-alcoholic fatty liver disease (NAFLD)
    • Ali R and Cusi K (2009) New diagnostic and treatment approaches in non-alcoholic fatty liver disease (NAFLD). Ann Med 41:265-278.
    • (2009) Ann Med , vol.41 , pp. 265-278
    • Ali, R.1    Cusi, K.2
  • 4
    • 77954762075 scopus 로고    scopus 로고
    • Functions and transcriptional regulation of adult human hepatic UDPglucuronosyl-transferases (UGTs): Mechanisms responsible for interindividual variation of UGT levels
    • Bock KW (2010) Functions and transcriptional regulation of adult human hepatic UDPglucuronosyl-transferases (UGTs): mechanisms responsible for interindividual variation of UGT levels. Biochem Pharmacol 80:771-777.
    • (2010) Biochem Pharmacol , vol.80 , pp. 771-777
    • Bock, K.W.1
  • 5
    • 78649433367 scopus 로고    scopus 로고
    • Histopathology of nonalcoholic fatty liver disease
    • Brunt EM and Tiniakos DG (2010) Histopathology of nonalcoholic fatty liver disease. World J Gastroenterol 16:5286-5296.
    • (2010) World J Gastroenterol , vol.16 , pp. 5286-5296
    • Brunt, E.M.1    Tiniakos, D.G.2
  • 7
    • 0035197725 scopus 로고    scopus 로고
    • Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identification of relevant acetaminophen UDP- glucuronosyltransferase isoforms
    • Court MH, Duan SX, von Moltke LL, Greenblatt DJ, Patten CJ, Miners JO, and Mackenzie PI (2001) Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. J Pharmacol Exp Ther 299:998-1006.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 998-1006
    • Court, M.H.1    Duan, S.X.2    Von Moltke, L.L.3    Greenblatt, D.J.4    Patten, C.J.5    Miners, J.O.6    MacKenzie, P.I.7
  • 8
    • 74549132748 scopus 로고    scopus 로고
    • Interindividual variability in hepatic drug glucuronidation: Studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system
    • Court MH (2010) Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system. Drug Metab Rev 42:209-224.
    • (2010) Drug Metab Rev , vol.42 , pp. 209-224
    • Court, M.H.1
  • 9
    • 0028960137 scopus 로고
    • Localization of uridine 59-diphosphate-glucuronosyltransferase in human liver injury
    • Debinski HS, Lee CS, Danks JA, Mackenzie PI, and Desmond PV (1995) Localization of uridine 59-diphosphate-glucuronosyltransferase in human liver injury. Gastroenterology 108:1464-1469.
    • (1995) Gastroenterology , vol.108 , pp. 1464-1469
    • Debinski, H.S.1    Lee, C.S.2    Danks, J.A.3    MacKenzie, P.I.4    Desmond, P.V.5
  • 12
    • 78649549021 scopus 로고    scopus 로고
    • Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease
    • Hardwick RN, Fisher CD, Canet MJ, Lake AD, and Cherrington NJ (2010) Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metab Dispos 38:2293-2301.
    • (2010) Drug Metab Dispos , vol.38 , pp. 2293-2301
    • Hardwick, R.N.1    Fisher, C.D.2    Canet, M.J.3    Lake, A.D.4    Cherrington, N.J.5
  • 13
    • 81855206575 scopus 로고    scopus 로고
    • Variations in ATPbinding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease
    • Hardwick RN, Fisher CD, Canet MJ, Scheffer GL, and Cherrington NJ (2011) Variations in ATPbinding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. Drug Metab Dispos 39:2395-2402.
    • (2011) Drug Metab Dispos , vol.39 , pp. 2395-2402
    • Hardwick, R.N.1    Fisher, C.D.2    Canet, M.J.3    Scheffer, G.L.4    Cherrington, N.J.5
  • 14
    • 41849104724 scopus 로고    scopus 로고
    • On the sulfation and methylation of catecholestrogens in human mammary epithelial cells and breast cancer cells
    • Hui Y, Yasuda S, Liu MY, Wu YY, and Liu MC (2008) On the sulfation and methylation of catecholestrogens in human mammary epithelial cells and breast cancer cells. Biol Pharm Bull 31:769-773.
    • (2008) Biol Pharm Bull , vol.31 , pp. 769-773
    • Hui, Y.1    Yasuda, S.2    Liu, M.Y.3    Wu, Y.Y.4    Liu, M.C.5
  • 16
    • 63449132897 scopus 로고    scopus 로고
    • Ventromedial hypothalamic lesions change the expression of neuron-related genes and immune-related genes in rat liver
    • Kiba T, Kintaka Y, Suzuki Y, Nakata E, Ishigaki Y, and Inoue S (2009) Ventromedial hypothalamic lesions change the expression of neuron-related genes and immune-related genes in rat liver. Neurosci Lett 455:14-16.
    • (2009) Neurosci Lett , vol.455 , pp. 14-16
    • Kiba, T.1    Kintaka, Y.2    Suzuki, Y.3    Nakata, E.4    Ishigaki, Y.5    Inoue, S.6
  • 17
    • 31944452253 scopus 로고    scopus 로고
    • The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
    • King BM (2006) The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav 87:221-244.
    • (2006) Physiol Behav , vol.87 , pp. 221-244
    • King, B.M.1
  • 21
    • 41549125368 scopus 로고    scopus 로고
    • Structure, function and polymorphism of human cytosolic sulfotransferases
    • Lindsay J, Wang LL, Li Y, and Zhou SF (2008) Structure, function and polymorphism of human cytosolic sulfotransferases. Curr Drug Metab 9:99-105.
    • (2008) Curr Drug Metab , vol.9 , pp. 99-105
    • Lindsay, J.1    Wang, L.L.2    Li, Y.3    Zhou, S.F.4
  • 23
    • 0030247013 scopus 로고    scopus 로고
    • Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts
    • Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, and Cohen SD (1996) Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts. Toxicol Appl Pharmacol 140: 30-38.
    • (1996) Toxicol Appl Pharmacol , vol.140 , pp. 30-38
    • Manautou, J.E.1    Tveit, A.2    Hoivik, D.J.3    Khairallah, E.A.4    Cohen, S.D.5
  • 25
    • 80053397336 scopus 로고    scopus 로고
    • Epidemiology of the metabolic syndrome in the USA
    • McCullough AJ (2011) Epidemiology of the metabolic syndrome in the USA. J Dig Dis 12: 333-340.
    • (2011) J Dig Dis , vol.12 , pp. 333-340
    • McCullough, A.J.1
  • 26
    • 74549142010 scopus 로고    scopus 로고
    • UGT3A: Novel UDP-glycosyltransferases of the UGT superfamily
    • Meech R and Mackenzie PI (2010) UGT3A: novel UDP-glycosyltransferases of the UGT superfamily. Drug Metab Rev 42:45-54.
    • (2010) Drug Metab Rev , vol.42 , pp. 45-54
    • Meech, R.1    MacKenzie, P.I.2
  • 27
    • 79960745166 scopus 로고    scopus 로고
    • Drug metabolism alterations in nonalcoholic fatty liver disease
    • Merrell MD and Cherrington NJ (2011) Drug metabolism alterations in nonalcoholic fatty liver disease. Drug Metab Rev 43:317-334.
    • (2011) Drug Metab Rev , vol.43 , pp. 317-334
    • Merrell, M.D.1    Cherrington, N.J.2
  • 29
    • 74549222703 scopus 로고    scopus 로고
    • The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drugdrug interaction potential
    • Miners JO, Mackenzie PI, and Knights KM (2010) The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drugdrug interaction potential. Drug Metab Rev 42:196-208.
    • (2010) Drug Metab Rev , vol.42 , pp. 196-208
    • Miners, J.O.1    MacKenzie, P.I.2    Knights, K.M.3
  • 30
    • 65549114152 scopus 로고    scopus 로고
    • Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice
    • Reisman SA, Csanaky IL, Aleksunes LM, and Klaassen CD (2009) Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. Toxicol Sci 109:31-40.
    • (2009) Toxicol Sci , vol.109 , pp. 31-40
    • Reisman, S.A.1    Csanaky, I.L.2    Aleksunes, L.M.3    Klaassen, C.D.4
  • 31
    • 70350319524 scopus 로고    scopus 로고
    • Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: The SULT "pie"
    • Riches Z, Stanley EL, Bloomer JC, and Coughtrie MW (2009) Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT "pie". Drug Metab Dispos 37:2255-2261.
    • (2009) Drug Metab Dispos , vol.37 , pp. 2255-2261
    • Riches, Z.1    Stanley, E.L.2    Bloomer, J.C.3    Coughtrie, M.W.4
  • 32
    • 0034534895 scopus 로고    scopus 로고
    • Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions
    • Ritter JK (2000) Roles of glucuronidation and UDP- glucuronosyltransferases in xenobiotic bioactivation reactions. Chem Biol Interact 129:171-193.
    • (2000) Chem Biol Interact , vol.129 , pp. 171-193
    • Ritter, J.K.1
  • 33
    • 56649107955 scopus 로고    scopus 로고
    • Hepatic, cardiovascular, and endocrine outcomes of the histological subphenotypes of nonalcoholic fatty liver disease
    • Rubinstein E, Lavine JE, and Schwimmer JB (2008) Hepatic, cardiovascular, and endocrine outcomes of the histological subphenotypes of nonalcoholic fatty liver disease. Semin Liver Dis 28:380-385.
    • (2008) Semin Liver Dis , vol.28 , pp. 380-385
    • Rubinstein, E.1    Lavine, J.E.2    Schwimmer, J.B.3
  • 34
    • 79959795387 scopus 로고    scopus 로고
    • NASH: A global health problem
    • Sanyal AJ (2011) NASH: A global health problem. Hepatol Res 41:670-674.
    • (2011) Hepatol Res , vol.41 , pp. 670-674
    • Sanyal, A.J.1
  • 35
    • 75649093034 scopus 로고    scopus 로고
    • Activity of sulfotransferase 1A1 is dramatically upregulated in patients with hepatocellular carcinoma secondary to chronic hepatitis B virus infection
    • Wang XR, Qu ZQ, Li XD, Liu HL, He P, Fang BX, Xiao J, Huang W, and Wu MC (2010) Activity of sulfotransferase 1A1 is dramatically upregulated in patients with hepatocellular carcinoma secondary to chronic hepatitis B virus infection. Cancer Sci 101:412-415.
    • (2010) Cancer Sci , vol.101 , pp. 412-415
    • Wang, X.R.1    Qu, Z.Q.2    Li, X.D.3    Liu, H.L.4    He, P.5    Fang, B.X.6    Xiao, J.7    Huang, W.8    Wu, M.C.9
  • 36
    • 18244393185 scopus 로고    scopus 로고
    • Oral contraceptives as substrates and inhibitors for human cytosolic SULTs
    • Yasuda S, Suiko M, and Liu MC (2005) Oral contraceptives as substrates and inhibitors for human cytosolic SULTs. J Biochem 137:401-406.
    • (2005) J Biochem , vol.137 , pp. 401-406
    • Yasuda, S.1    Suiko, M.2    Liu, M.C.3
  • 38
    • 33644842869 scopus 로고    scopus 로고
    • Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites
    • Zamek-Gliszczynski MJ, Hoffmaster KA, Nezasa K, Tallman MN, and Brouwer KL (2006) Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites. Eur J Pharm Sci 27: 447-486.
    • (2006) Eur J Pharm Sci , vol.27 , pp. 447-486
    • Zamek-Gliszczynski, M.J.1    Hoffmaster, K.A.2    Nezasa, K.3    Tallman, M.N.4    Brouwer, K.L.5


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