메뉴 건너뛰기




Volumn 70, Issue 5, 2013, Pages 395-406

Management of advanced colorectal cancer, part 1

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; BEVACIZUMAB; CAPECITABINE; CETUXIMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; PANITUMUMAB; REGORAFENIB;

EID: 84874086467     PISSN: 10792082     EISSN: 15352900     Source Type: Journal    
DOI: 10.2146/ajhp110532     Document Type: Review
Times cited : (27)

References (107)
  • 3
    • 0041435762 scopus 로고    scopus 로고
    • (accessed 2013 Jan 10)
    • American Cancer Society. Cancer facts and figures 2012. www.cancer.org/ACS/groups/content/@epidemiologysurveilance/documents/document/ ACSPC-031941.pdf (accessed 2013 Jan 10).
    • Cancer Facts and Figures 2012
  • 5
    • 84874088482 scopus 로고    scopus 로고
    • (accessed 2013 Jan 28)
    • National Cancer Institute, National Institutes of Health. Drugs approved for colon and rectal cancer. www.cancer. gov/cancertopics/druginfo/colorectal cancer (accessed 2013 Jan 28).
    • Drugs Approved for Colon and Rectal Cancer
  • 6
    • 2142703727 scopus 로고    scopus 로고
    • Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
    • Grothey A, Sargent D, Goldberg RM et al. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol. 2004; 22:1209-14.
    • (2004) J Clin Oncol , vol.22 , pp. 1209-1214
    • Grothey, A.1    Sargent, D.2    Goldberg, R.M.3
  • 7
    • 33644825856 scopus 로고    scopus 로고
    • Overall survival of patients with advanced colorectal cancer correlates with availability of fluoroura-cil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line
    • Letter
    • Grothey A, Sargent D. Overall survival of patients with advanced colorectal cancer correlates with availability of fluoroura-cil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line. J Clin Oncol. 2005; 23:9441-2. Letter.
    • (2005) J Clin Oncol. , vol.23 , pp. 9441-9442
    • Grothey, A.1    Sargent, D.2
  • 8
    • 33846404530 scopus 로고    scopus 로고
    • The continuum of care: A paradigm for the management of metastatic colorectal cancer
    • Goldberg RM, Rothenberg ML, van Cutsem E et al. The continuum of care: a paradigm for the management of metastatic colorectal cancer. Oncologist. 2007; 12:38-50.
    • (2007) Oncologist , vol.12 , pp. 38-50
    • Goldberg, R.M.1    Rothenberg, M.L.2    Van Cutsem, E.3
  • 9
    • 0038387494 scopus 로고    scopus 로고
    • 5-fluorouracil: Mechanisms of action and clinical strategies
    • Longley DB, Harkin D P, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003; 3:330-8.
    • (2003) Nat Rev Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 10
    • 0029923720 scopus 로고    scopus 로고
    • Phase III study of bolus versus infusion fluorouracil with or without cisplatin in advanced colorectal cancer
    • Hansen RM, Ryan L, Anderson T et al. Phase III study of bolus versus infusion fluorouracil with or without cisplatin in advanced colorectal cancer. J Natl Cancer Inst. 1996; 88:668-74.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 668-674
    • Hansen, R.M.1    Ryan, L.2    Anderson, T.3
  • 11
    • 0026460966 scopus 로고
    • Systemic infusion versus bolus chemotherapy in measurable colorectal cancer
    • Weinerman B, Shah A. Fields A et al. Systemic infusion versus bolus chemotherapy in measurable colorectal cancer. Am J Clin Oncol. 1992; 15:518-23.
    • (1992) Am J Clin Oncol , vol.15 , pp. 518-523
    • Weinerman, B.1    Shah, A.2    Fields, A.3
  • 12
    • 0029012118 scopus 로고
    • Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group study
    • Leichman CG, Fleming TR, Muggia FM et al. Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study. J Clin Oncol. 1995; 13:1303-11.
    • (1995) J Clin Oncol , vol.13 , pp. 1303-1311
    • Leichman, C.G.1    Fleming, T.R.2    Muggia, F.M.3
  • 13
    • 0024539308 scopus 로고
    • A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid-Atlantic Oncology Program study
    • Lokich JJ, Ahlgren JD, Gullo JJ et al. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program study. J Clin Oncol. 1989; 7:425-32.
    • (1989) J Clin Oncol , vol.7 , pp. 425-432
    • Lokich, J.J.1    Ahlgren, J.D.2    Gullo, J.J.3
  • 14
    • 0031431131 scopus 로고    scopus 로고
    • 5-Fluorouracil (5-FU) continuous intravenous infusion compared with bolus administration. Final results of a randomised trial in metastatic colorectal cancer
    • Rougier P, Pailiot B, Laplanche A et al. 5-Fluorouracil (5-FU) continuous intravenous infusion compared with bolus administration. Final results of a randomised trial in metastatic colorectal cancer. Eur J Cancer. 1997; 33:1789-93.
    • (1997) Eur J Cancer , vol.33 , pp. 1789-1793
    • Rougier, P.1    Pailiot, B.2    Laplanche, A.3
  • 15
    • 0345342761 scopus 로고
    • 5-Fluorouracil and folinic acid in the treatment of colorectal carcinoma: A randomized trial of two different schedules of administration
    • Jerusalem, Israel Aug 27-Sep 1
    • Isacson S. 5-Fluorouracil and folinic acid in the treatment of colorectal carcinoma: a randomized trial of two different schedules of administration. Second International Conference on Gastro-Intestinal Cancer, Jerusalem, Israel; 1989 Aug 27-Sep 1.
    • (1989) Second International Conference on Gastro-Intestinal Cancer
    • Isacson, S.1
  • 16
    • 0344109583 scopus 로고    scopus 로고
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
    • Meta-analysis Group in Cancer
    • Meta-analysis Group in Cancer. Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol. 1998; 16:301-8.
    • (1998) J Clin Oncol , vol.16 , pp. 301-308
  • 17
    • 0028175144 scopus 로고
    • Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer
    • Buroker TR, O'Connell MJ, Wieand HS et al. Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer. J Clin Oncol. 1994; 12:14-20.
    • (1994) J Clin Oncol , vol.12 , pp. 14-20
    • Buroker, T.R.1    O'Connell, M.J.2    Wieand, H.S.3
  • 18
    • 4644252335 scopus 로고    scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: An updated meta-analysis
    • Thirion P, Michiels S, Pignon JP et al. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis. J Clin Oncol. 2004; 22:3766-75.
    • (2004) J Clin Oncol , vol.22 , pp. 3766-3775
    • Thirion, P.1    Michiels, S.2    Pignon, J.P.3
  • 19
    • 0023802172 scopus 로고
    • High-dose folinic acid and 5-fluorouracil bolus and continuous infusion in advanced colorectal cancer
    • De Gramont A, Krulik M, Cady J et al. High-dose folinic acid and 5-fluorouracil bolus and continuous infusion in advanced colorectal cancer. Eur J Cancer Clin Oncol. 1988; 24:1499-503.
    • (1988) Eur J Cancer Clin Oncol , vol.24 , pp. 1499-1503
    • De Gramont, A.1    Krulik, M.2    Cady, J.3
  • 20
    • 0031019918 scopus 로고    scopus 로고
    • Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leu-covorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study
    • De Gramont A, Bosset JF, Milan C et al. Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leu-covorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. J Clin Oncol. 1997; 15:808-15.
    • (1997) J Clin Oncol , vol.15 , pp. 808-815
    • De Gramont, A.1    Bosset, J.F.2    Milan, C.3
  • 23
    • 70350168945 scopus 로고    scopus 로고
    • Is levoleucovorin an alternative to racemic leucovorin? A literature review
    • Kovoor PA, Karim SM, Marshall JL. Is levoleucovorin an alternative to racemic leucovorin? A literature review. Clin Colorectal Cancer. 2009; 8:200-6.
    • (2009) Clin Colorectal Cancer , vol.8 , pp. 200-206
    • Kovoor, P.A.1    Karim, S.M.2    Marshall, J.L.3
  • 24
    • 84874061872 scopus 로고    scopus 로고
    • New York, NY: Pharmacia & Upjohn Co, Division of Pfizer Inc. Aug.
    • Camptosar (irinotecan) prescribing information. New York, NY: Pharmacia & Upjohn Co, Division of Pfizer Inc.; 2010 Aug.
    • (2010) Camptosar (irinotecan) Prescribing Information
  • 25
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for meta-static colorectal cancer
    • for the Irinotecan Study Group
    • Saltz LB, Cox JV, Blanke C et al., for the Irinotecan Study Group. Irinotecan plus fluorouracil and leucovorin for meta-static colorectal cancer. N Engl J Med. 2000; 343:905-14.
    • (2000) N Engl J Med , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 26
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluoro-uracil compared with fluorouracil alone as first line treatment for metastatic colorectal cancer: A multicentre randomised trial
    • Douillard JY, Cunningham D, Roth AD et al. Irinotecan combined with fluoro-uracil compared with fluorouracil alone as first line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet. 2000; 355:1041-7.
    • (2000) Lancet , vol.355 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3
  • 27
    • 24644432555 scopus 로고    scopus 로고
    • Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organization for Research and Treatment of Cancer Gastrointestinal Group study 40986
    • Kohne CH, van Cutsem E, Wils JA et al. Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organization for Research and Treatment of Cancer Gastrointestinal Group study 40986. J Clin Oncol. 2005; 23:4811-4.
    • (2005) J Clin Oncol , vol.23 , pp. 4811-4814
    • Kohne, C.H.1    Van Cutsem, E.2    Wils, J.A.3
  • 28
    • 33846042717 scopus 로고    scopus 로고
    • Comparison of the tolerance and efficacy of LV5FU2-CPT11 and FOLFIRI regimens in front-line treatment of advanced colorectal cancer: A pooled analysis of 254 patients included in 2 randomised trials. ASCO annual meeting proceedings (post-meeting edition)
    • abstract 3576
    • Mitry E, Tournigand C, Andre T et al. Comparison of the tolerance and efficacy of LV5FU2-CPT11 and FOLFIRI regimens in front-line treatment of advanced colorectal cancer: a pooled analysis of 254 patients included in 2 randomised trials. ASCO annual meeting proceedings (post-meeting edition). J Clin Oncol. 2004; 22(suppl):abstract 3576.
    • (2004) J Clin Oncol. , vol.22 , Issue.SUPPL.
    • Mitry, E.1    Tournigand, C.2    Andre, T.3
  • 29
    • 33645309877 scopus 로고    scopus 로고
    • FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin, and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil, and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
    • Souglakos J, Androulakis N, Syrigos K et al. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin, and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil, and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer. 2006; 94:798-805.
    • (2006) Br J Cancer , vol.94 , pp. 798-805
    • Souglakos, J.1    Androulakis, N.2    Syrigos, K.3
  • 30
    • 34249000361 scopus 로고    scopus 로고
    • Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
    • Falcone A, Ricci S, Brunetti I et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol. 2007; 25:1670-6.
    • (2007) J Clin Oncol. , vol.25 , pp. 1670-1676
    • Falcone, A.1    Ricci, S.2    Brunetti, I.3
  • 31
    • 78651297593 scopus 로고    scopus 로고
    • Randomized trial of two induction chemotherapy regimens in metastatic colorectal cancer: An updated analysis
    • Masi G, Vasile E, Loupakis F et al. Randomized trial of two induction chemotherapy regimens in metastatic colorectal cancer: an updated analysis. J Natl Cancer Inst. 2011; 103:21-30.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 21-30
    • Masi, G.1    Vasile, E.2    Loupakis, F.3
  • 32
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, Andre T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol. 2004; 22:229-37.
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    Andre, T.2    Achille, E.3
  • 33
    • 24644457747 scopus 로고    scopus 로고
    • Phase III randomized trial of FOLFIRI versus FOLFOX 4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico dell'Italia Meridionale
    • Colucci G, Gebbia V, Paoletti G et al. Phase III randomized trial of FOLFIRI versus FOLFOX 4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol. 2005; 23:4866-75.
    • (2005) J Clin Oncol. , vol.23 , pp. 4866-4875
    • Colucci, G.1    Gebbia, V.2    Paoletti, G.3
  • 35
    • 0034016343 scopus 로고    scopus 로고
    • Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: Results of a randomized phase II study
    • Van Cutsem E, Findlay M, Osterwalder B et al. Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study. J Clin Oncol. 2000; 18:1337-45.
    • (2000) J Clin Oncol. , vol.18 , pp. 1337-1345
    • Van Cutsem, E.1    Findlay, M.2    Osterwalder, B.3
  • 36
    • 21144452813 scopus 로고    scopus 로고
    • Capecitabine as first-line treatment for patients older than 70 years with metastatic colorectal cancer: An Oncopaz Cooperative Group study
    • Feliu J, Escudero P, Llosa F et al. Capecitabine as first-line treatment for patients older than 70 years with metastatic colorectal cancer: an Oncopaz Cooperative Group study. J Clin Oncol. 2005; 23:3104-11.
    • (2005) J Clin Oncol. , vol.23 , pp. 3104-3111
    • Feliu, J.1    Escudero, P.2    Llosa, F.3
  • 37
    • 33748118471 scopus 로고    scopus 로고
    • A phase II study of the global dose and schedule of capecitabine in Japanese patients with metastatic colorectal cancer
    • Hyodo I, Shirao K, Doi T et al. A phase II study of the global dose and schedule of capecitabine in Japanese patients with metastatic colorectal cancer. Jpn J Clin Oncol. 2006; 36:410-7.
    • (2006) Jpn J Clin Oncol. , vol.36 , pp. 410-417
    • Hyodo, I.1    Shirao, K.2    Doi, T.3
  • 38
    • 6044243224 scopus 로고    scopus 로고
    • Single-agent capecitabine in patients with meta-static colorectal cancer refractory to 5-fluorouracil-leucovorin chemotherapy
    • Lee JJ, Kim TM, Yu SJ et al. Single-agent capecitabine in patients with meta-static colorectal cancer refractory to 5-fluorouracil-leucovorin chemotherapy. Jpn J Clin Oncol. 2004; 34:400-4.
    • (2004) Jpn J Clin Oncol. , vol.34 , pp. 400-404
    • Lee, J.J.1    Kim, T.M.2    Yu, S.J.3
  • 39
    • 2942662092 scopus 로고    scopus 로고
    • Phase II study of capecitabine in patients with fluorouracil-resistant metastatic colorectal carcinoma
    • Hoff PM, Pazdur R, Lassere Y et al. Phase II study of capecitabine in patients with fluorouracil-resistant metastatic colorectal carcinoma. J Clin Oncol. 2004; 22:2078-83.
    • (2004) J Clin Oncol. , vol.22 , pp. 2078-2083
    • Hoff, P.M.1    Pazdur, R.2    Lassere, Y.3
  • 40
    • 0035871538 scopus 로고    scopus 로고
    • Comparison of oral capecitabine versus intra-venous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study
    • Hoff PM, Ansari R, Batist G et al. Comparison of oral capecitabine versus intra-venous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol. 2001; 19:2282-92.
    • (2001) J Clin Oncol. , vol.19 , pp. 2282-2292
    • Hoff, P.M.1    Ansari, R.2    Batist, G.3
  • 41
    • 0035503151 scopus 로고    scopus 로고
    • Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
    • Van Cutsem E, Twelves C, Cassidy J et al. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol. 2001; 19:4097-106.
    • (2001) J Clin Oncol. , vol.19 , pp. 4097-4106
    • Van Cutsem, E.1    Twelves, C.2    Cassidy, J.3
  • 42
    • 11144354462 scopus 로고    scopus 로고
    • Oral capecitabine vs. intravenous 5-fluorouracil and leucovorin: Integrated efficacy data and novel analyses from two large, randomized, phase III trials
    • Van Cutsem E, Hoff PM, Harper P et al. Oral capecitabine vs. intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomized, phase III trials. Br J Cancer. 2004; 90:1190-7.
    • (2004) Br J Cancer , vol.90 , pp. 1190-1197
    • Van Cutsem, E.1    Hoff, P.M.2    Harper, P.3
  • 43
    • 0036176033 scopus 로고    scopus 로고
    • Capecitabine as first-line treatment in colorectal cancer. Pooled data from two large phase III trials
    • for the Xeloda colorectal cancer group
    • Twelves C, for the Xeloda colorectal cancer group. Capecitabine as first-line treatment in colorectal cancer. Pooled data from two large phase III trials. Eur J Cancer. 2002; 38(suppl 2):15-20.
    • (2002) Eur J Cancer , vol.38 , Issue.SUPPL. 2 , pp. 15-20
    • Twelves, C.1
  • 44
    • 43749111108 scopus 로고    scopus 로고
    • Potential regional differences for the tol-erability profiles of fluoropyrimidines
    • Haller DG, Cassidy J, Clarke SJ et al. Potential regional differences for the tol-erability profiles of fluoropyrimidines. J Clin Oncol. 2008; 26:2118-23.
    • (2008) J Clin Oncol. , vol.26 , pp. 2118-2123
    • Haller, D.G.1    Cassidy, J.2    Clarke, S.J.3
  • 45
    • 73949157627 scopus 로고    scopus 로고
    • Capecitabine: Have we got the dose right?
    • Midgley R, Kerr DJ. Capecitabine: have we got the dose right? Nat Clin Pract Oncol. 2009; 6:17-24.
    • (2009) Nat Clin Pract Oncol. , vol.6 , pp. 17-24
    • Midgley, R.1    Kerr, D.J.2
  • 46
    • 4444351107 scopus 로고    scopus 로고
    • Firstline chemotherapy with irinotecan plus capecitabine for advanced colorectal cancer
    • Park SH, Bang SM, Cho EK et al. Firstline chemotherapy with irinotecan plus capecitabine for advanced colorectal cancer. Oncology. 2004; 66:353-7.
    • (2004) Oncology , vol.66 , pp. 353-357
    • Park, S.H.1    Bang, S.M.2    Cho, E.K.3
  • 47
    • 17144377083 scopus 로고    scopus 로고
    • Final analysis of irinotecan (CPT-11) and capecitabine (X) as first-line treatment of locally advanced (LA) or metastatic colorectal cancer (MCRC)
    • abstract 3610
    • Munoz A, Salud A, Alonso V et al. Final analysis of irinotecan (CPT-11) and capecitabine (X) as first-line treatment of locally advanced (LA) or metastatic colorectal cancer (MCRC). J Clin Oncol. 2004; 22(suppl):272S, abstract 3610.
    • (2004) J Clin Oncol. , vol.22 , Issue.SUPPL.
    • Munoz, A.1    Salud, A.2    Alonso, V.3
  • 48
    • 34548440297 scopus 로고    scopus 로고
    • Capecitabine plus 3-weekly irinotecan (XELIRI regimen) as first-time chemotherapy for metastatic colorectal cancer: Phase II trial results
    • Patt YZ, Lee FC, Liebmann JE et al. Capecitabine plus 3-weekly irinotecan (XELIRI regimen) as first-time chemotherapy for metastatic colorectal cancer: phase II trial results. Am J Clin Oncol. 2007; 30:350-7.
    • (2007) Am J Clin Oncol. , vol.30 , pp. 350-357
    • Patt, Y.Z.1    Lee, F.C.2    Liebmann, J.E.3
  • 49
    • 45949094172 scopus 로고    scopus 로고
    • Irinotecan plus capecitabine as first-line chemotherapy in advanced colorectal cancer
    • Gannatas C, Michalaki V, Gennatas S et al. Irinotecan plus capecitabine as first-line chemotherapy in advanced colorectal cancer. Anticancer Res. 2008; 28:1923-6.
    • (2008) Anticancer Res. , vol.28 , pp. 1923-1926
    • Gannatas, C.1    Michalaki, V.2    Gennatas, S.3
  • 50
    • 70349675233 scopus 로고    scopus 로고
    • Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: A phase II study of the Spanish GOTI group
    • Garcia-Alfonso P, Munoz-Martin A, Mendez-Urena M et al. Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: a phase II study of the Spanish GOTI group. Br J Cancer. 2009; 101:1039-43.
    • (2009) Br J Cancer , vol.101 , pp. 1039-1043
    • Garcia-Alfonso, P.1    Munoz-Martin, A.2    Mendez-Urena, M.3
  • 51
    • 21844472538 scopus 로고    scopus 로고
    • Results of a phase II open-label study of capecitabine in combination with irinotecan as first-line treatment for metastatic colorectal cancer
    • Cartwright T, Lopez T, Vukelja SJ et al. Results of a phase II open-label study of capecitabine in combination with irinotecan as first-line treatment for metastatic colorectal cancer. Clin Colorectal Cancer. 2005; 5:50-6.
    • (2005) Clin Colorectal Cancer , vol.5 , pp. 50-56
    • Cartwright, T.1    Lopez, T.2    Vukelja, S.J.3
  • 52
    • 21344457969 scopus 로고    scopus 로고
    • A phase I/II pharmacokinetic study of irinotecan in combination with capecitabine as first-line therapy for advanced colorectal cancer
    • Rea DW, Nortier JW, Ten Bokkel Huinink WW et al. A phase I/II pharmacokinetic study of irinotecan in combination with capecitabine as first-line therapy for advanced colorectal cancer. Ann Oncol. 2005; 16:1123-32.
    • (2005) Ann Oncol. , vol.16 , pp. 1123-1132
    • Rea, D.W.1    Nortier, J.W.2    Ten Bokkel Huinink, W.W.3
  • 53
    • 21344466292 scopus 로고    scopus 로고
    • Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: A Korean Cancer Study Group trial
    • Kim TW, Kang WK, Chang HM et al. Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial. Acta Oncol. 2005; 44:230-5.
    • (2005) Acta Oncol. , vol.44 , pp. 230-235
    • Kim, T.W.1    Kang, W.K.2    Chang, H.M.3
  • 54
    • 84874047669 scopus 로고    scopus 로고
    • Phase II study of capecitabine and irinotecan as first-line treatment in metastatic colorectal cancer: First trial of the Brazilian Oncology Consortium (BOC-CRC)
    • abstract 300S
    • Barrios CH, Viola F, Camill-Coura L et al. Phase II study of capecitabine and irinotecan as first-line treatment in metastatic colorectal cancer: first trial of the Brazilian Oncology Consortium (BOC-CRC). J Clin Oncol. 2004; 22(suppl):abstract 300S.
    • (2004) J Clin Oncol. , vol.22 , Issue.SUPPL.
    • Barrios, C.H.1    Viola, F.2    Camill-Coura, L.3
  • 55
    • 36348984951 scopus 로고    scopus 로고
    • Phase-II study of dose-attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer
    • El-Rayes BF, Zalupski MM, Manza SG et al. Phase-II study of dose-attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer. Cancer Chemother Pharmacol. 2008; 61:283-9.
    • (2008) Cancer Chemother Pharmacol. , vol.61 , pp. 283-289
    • El-Rayes, B.F.1    Zalupski, M.M.2    Manza, S.G.3
  • 56
    • 77953360395 scopus 로고    scopus 로고
    • Phase II trial of irinotecan and capecitabine in patients with advanced colorectal cancer (ACRC)
    • abstract 3714
    • Ahn J, Jung KH, Park YS et al. Phase II trial of irinotecan and capecitabine in patients with advanced colorectal cancer (ACRC). J Clin Oncol. 2005; 23(suppl):abstract 3714.
    • (2005) J Clin Oncol. , vol.23 , Issue.SUPPL.
    • Ahn, J.1    Jung, K.H.2    Park, Y.S.3
  • 57
    • 84858860652 scopus 로고    scopus 로고
    • Firstline treatment with capecitabine combined with irinotecan in patients with advanced colorectal carcinoma
    • Zidan J, Basher W, Chetver L et al. Firstline treatment with capecitabine combined with irinotecan in patients with advanced colorectal carcinoma. J Clin Gastroenterol. 2012; 46:e27-30.
    • (2012) J Clin Gastroenterol. , vol.46
    • Zidan, J.1    Basher, W.2    Chetver, L.3
  • 58
    • 9144255466 scopus 로고    scopus 로고
    • Randomized multicenter phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma
    • Bajetta E, di Bartolomeo M, Mariani L et al. Randomized multicenter phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma. Cancer. 2004; 100:279-87.
    • (2004) Cancer , vol.100 , pp. 279-287
    • Bajetta, E.1    Di Bartolomeo, M.2    Mariani, L.3
  • 59
    • 20044384354 scopus 로고    scopus 로고
    • A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: Efficacy, quality-of-life and toxicity
    • Borner MM, Bernhard J, Dietrich D et al. A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity. Ann Oncol. 2005; 16:282-8.
    • (2005) Ann Oncol. , vol.16 , pp. 282-288
    • Borner, M.M.1    Bernhard, J.2    Dietrich, D.3
  • 60
    • 77957811330 scopus 로고    scopus 로고
    • Differences in efficacy and safety between capecitabine and infusional 5-fluorouracil when combined with irinotecan for the treatment of metastatic colorectal cancer
    • Montagnani F, Chiriatti A, Licitra S et al. Differences in efficacy and safety between capecitabine and infusional 5-fluorouracil when combined with irinotecan for the treatment of metastatic colorectal cancer. Clin Colorectal Cancer. 2010; 9:243-7.
    • (2010) Clin Colorectal Cancer , vol.9 , pp. 243-247
    • Montagnani, F.1    Chiriatti, A.2    Licitra, S.3
  • 61
    • 36048960109 scopus 로고    scopus 로고
    • Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study
    • Fuchs CS, Marshall J, Mitchell E et al. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C study. J Clin Oncol. 2007; 25:4779-86.
    • (2007) J Clin Oncol. , vol.25 , pp. 4779-4786
    • Fuchs, C.S.1    Marshall, J.2    Mitchell, E.3
  • 63
    • 14644438655 scopus 로고    scopus 로고
    • Evolution of FOLFOX regimens in the treatment of advanced colorectal cancer
    • Reddy GK, Gibson AD, Price N. Evolution of FOLFOX regimens in the treatment of advanced colorectal cancer. Clin Colorect Cancer. 2005; 4:296-9.
    • (2005) Clin Colorect Cancer , vol.4 , pp. 296-299
    • Reddy, G.K.1    Gibson, A.D.2    Price, N.3
  • 64
    • 0000946948 scopus 로고
    • Oxaliplatin with high-dose folinic acid and 5-fluorouracil 48 hours infusion in pretreated metastatic colorectal cancer
    • abstract 666
    • de Gramont A, Gastiaburu J, Tournigand C et al. Oxaliplatin with high-dose folinic acid and 5-fluorouracil 48 hours infusion in pretreated metastatic colorectal cancer. ASCO Ann Meeting Proc. 1994; 13:220, abstract 666.
    • (1994) ASCO Ann Meeting Proc. , vol.13 , pp. 220
    • De Gramont, A.1    Gastiaburu, J.2    Tournigand, C.3
  • 65
    • 0030888321 scopus 로고    scopus 로고
    • Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated meta-static colorectal cancer
    • de Gramont A, Vignoud J, Tournigand C et al. Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated meta-static colorectal cancer. Eur J Cancer. 1997; 33:214-9.
    • (1997) Eur J Cancer , vol.33 , pp. 214-219
    • De Gramont, A.1    Vignoud, J.2    Tournigand, C.3
  • 66
    • 0031774842 scopus 로고    scopus 로고
    • Bimonthly high-dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX 3) for metastatic colorectal cancer resistant to the same leucovorin and 5-fluorouracil regimen
    • Andre T, Louvet C, Raymond E et al. Bimonthly high-dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX 3) for metastatic colorectal cancer resistant to the same leucovorin and 5-fluorouracil regimen. Ann Oncol. 1998; 9:1251-3.
    • (1998) Ann Oncol. , vol.9 , pp. 1251-1253
    • Andre, T.1    Louvet, C.2    Raymond, E.3
  • 67
    • 0032730143 scopus 로고    scopus 로고
    • Multicenter phase II trial of bi-monthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen
    • Andre T, Bensmaine MA, Louvet C et al. Multicenter phase II trial of bi-monthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen. J Clin Oncol. 1999; 17:3560-8.
    • (1999) J Clin Oncol. , vol.17 , pp. 3560-3568
    • Andre, T.1    Bensmaine, M.A.2    Louvet, C.3
  • 68
    • 33746805967 scopus 로고    scopus 로고
    • Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer; a North American Intergroup trial
    • Goldberg RM, Sargent DJ, Morton R et al. Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer; a North American Intergroup trial. J Clin Oncol. 2006; 24:3347-53.
    • (2006) J Clin Oncol. , vol.24 , pp. 3347-3353
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.3
  • 69
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol. 2000; 18:2938-47.
    • (2000) J Clin Oncol. , vol.18 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3
  • 70
    • 27744452928 scopus 로고    scopus 로고
    • Reduced dose intensity FOLFOX-4 as first line palliative chemotherapy in elderly patients with advanced colorectal cancer
    • Kim JH, Oh DY, Kim YJ et al. Reduced dose intensity FOLFOX-4 as first line palliative chemotherapy in elderly patients with advanced colorectal cancer. J Korean Med Sci. 2005; 20:806-10.
    • (2005) J Korean Med Sci. , vol.20 , pp. 806-810
    • Kim, J.H.1    Oh, D.Y.2    Kim, Y.J.3
  • 71
    • 70349977215 scopus 로고    scopus 로고
    • Colon cancer
    • Devita VT, Hellman S, Rosenberg SA, eds. 8th ed. Philadelphia: Lippincott Williams & Wilkins
    • Libutti SK, Saltz LB, Tepper JE. Colon cancer. In: Devita VT, Hellman S, Rosenberg SA, eds. Cancer principles and practice of oncology. 8th ed. Philadelphia: Lippincott Williams & Wilkins; 2008:1268.
    • (2008) Cancer Principles and Practice of Oncology , pp. 1268
    • Libutti, S.K.1    Saltz, L.B.2    Tepper, J.E.3
  • 72
    • 34250650940 scopus 로고    scopus 로고
    • Oxaliplatin/fluorouracil-leucovorin (FOLFOX4 and modified FOLFOX6) in patients with refractory or advanced colorectal cancer: Post-approval Japanese population experience
    • Shimizu T, Satoh T, Tamura K et al. Oxaliplatin/fluorouracil-leucovorin (FOLFOX4 and modified FOLFOX6) in patients with refractory or advanced colorectal cancer: post-approval Japanese population experience. Int J Clin Oncol. 2007; 12:218-23.
    • (2007) Int J Clin Oncol. , vol.12 , pp. 218-223
    • Shimizu, T.1    Satoh, T.2    Tamura, K.3
  • 73
    • 16244377696 scopus 로고    scopus 로고
    • Australian experience of a modified schedule of FOLFOX with high activity and tolerability and improved convenience in untreated metastatic colorectal cancer patients
    • Goldstein D, Mitchell P, Michael M et al. Australian experience of a modified schedule of FOLFOX with high activity and tolerability and improved convenience in untreated metastatic colorectal cancer patients. Br J Cancer. 2005; 92:832-7.
    • (2005) Br J Cancer , vol.92 , pp. 832-837
    • Goldstein, D.1    Mitchell, P.2    Michael, M.3
  • 74
    • 51049096390 scopus 로고    scopus 로고
    • Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome study
    • Matsumoto S, Nishimura T, Kanai M et al. Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome study. Chemotherapy. 2008; 54:395-403.
    • (2008) Chemotherapy , vol.54 , pp. 395-403
    • Matsumoto, S.1    Nishimura, T.2    Kanai, M.3
  • 75
    • 0035032625 scopus 로고    scopus 로고
    • High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7)
    • Maindrault-Goebel F, de Gramont A, Louvet C et al. High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7). Eur J Cancer. 2001; 37:1000-5.
    • (2001) Eur J Cancer , vol.37 , pp. 1000-1005
    • Maindrault-Goebel, F.1    De Gramont, A.2    Louvet, C.3
  • 76
    • 0033636033 scopus 로고    scopus 로고
    • Evaluation of oxaliplatin dose intensity in bimonthly leucovorin and 48 hour 5-fluorouracil continuous infusion regimens (FOLFOX) in pretreated metastatic colorectal cancer
    • Oncology Multidisciplinary Research Group (GERCOR)
    • Maindrault-Goebel F, de Gramont A, Louvet C et al. Evaluation of oxaliplatin dose intensity in bimonthly leucovorin and 48 hour 5-fluorouracil continuous infusion regimens (FOLFOX) in pretreated metastatic colorectal cancer. Oncology Multidisciplinary Research Group (GERCOR). Ann Oncol. 2000; 11:1477-83.
    • (2000) Ann Oncol. , vol.11 , pp. 1477-1483
    • Maindrault-Goebel, F.1    De Gramont, A.2    Louvet, C.3
  • 77
    • 34548242294 scopus 로고    scopus 로고
    • Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer
    • de Gramont A, Buyse M, Abrahantes JC et al. Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer. J Clin Oncol. 2007; 25:3224-9.
    • (2007) J Clin Oncol. , vol.25 , pp. 3224-3229
    • De Gramont, A.1    Buyse, M.2    Abrahantes, J.C.3
  • 78
    • 33644843853 scopus 로고    scopus 로고
    • OPTIMOX 1: A randomized study of FOLFOX 4 or FOLFOX 7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer - A GERCOR study
    • Tournigand C, Cervantes A, Andre T et al. OPTIMOX 1: a randomized study of FOLFOX 4 or FOLFOX 7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer - a GERCOR study. J Clin Oncol. 2006; 24:394-400.
    • (2006) J Clin Oncol. , vol.24 , pp. 394-400
    • Tournigand, C.1    Cervantes, A.2    Andre, T.3
  • 79
    • 73349089651 scopus 로고    scopus 로고
    • Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 study
    • Chibaudel B, Maindrault-Goebel F, Lledo G et al. Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 study. J Clin Oncol. 2009; 27:5727-33.
    • (2009) J Clin Oncol. , vol.27 , pp. 5727-5733
    • Chibaudel, B.1    Maindrault-Goebel, F.2    Lledo, G.3
  • 80
    • 77952353767 scopus 로고    scopus 로고
    • Meta-analysis of chemotherapy with irinotecan or oxaliplatin-involved regimens for untreated metastatic advanced colorectal cancer
    • Zhuang L, Bai J, Huang H et al. Meta-analysis of chemotherapy with irinotecan or oxaliplatin-involved regimens for untreated metastatic advanced colorectal cancer. Oncol Res. 2010; 18:437-44.
    • (2010) Oncol Res. , vol.18 , pp. 437-444
    • Zhuang, L.1    Bai, J.2    Huang, H.3
  • 81
    • 2942638081 scopus 로고    scopus 로고
    • XELOX (capecitabine plus oxaliplatin): Active first-line therapy in patients with metastatic colorectal cancer
    • Cassidy J, Tabernero J, Twelves C et al. XELOX (capecitabine plus oxaliplatin): active first-line therapy in patients with metastatic colorectal cancer. J Clin Oncol. 2004; 22:2084-91.
    • (2004) J Clin Oncol. , vol.22 , pp. 2084-2091
    • Cassidy, J.1    Tabernero, J.2    Twelves, C.3
  • 82
    • 33645731984 scopus 로고    scopus 로고
    • XELOX (capecitabine plus oxaliplatin) as first-line treatment for elderly patients over 70 years with advanced/metastatic colorectal cancer
    • Feliu J, Salud A, Escudero P et al. XELOX (capecitabine plus oxaliplatin) as first-line treatment for elderly patients over 70 years with advanced/metastatic colorectal cancer. Br J Cancer. 2006; 94:969-75.
    • (2006) Br J Cancer , vol.94 , pp. 969-975
    • Feliu, J.1    Salud, A.2    Escudero, P.3
  • 83
    • 24344440875 scopus 로고    scopus 로고
    • A phase II study of capecitabine plus oxaliplatin (XELOX): A new first-line option in metastatic colorectal cancer
    • Makatsoris T, Kalofonos H P, Aravantinos G et al. A phase II study of capecitabine plus oxaliplatin (XELOX): a new first-line option in metastatic colorectal cancer. Int J Gastrointest Cancer. 2005; 35:103-9.
    • (2005) Int J Gastrointest Cancer , vol.35 , pp. 103-109
    • Makatsoris, T.1    Kalofonos, H.P.2    Aravantinos, G.3
  • 84
    • 75149134401 scopus 로고    scopus 로고
    • Capecitabine and oxaliplatin (XELOX) as first-line treatment for patients with metastatic colorectal cancer
    • Karacetin D, Yalcin B, Okten B et al. Capecitabine and oxaliplatin (XELOX) as first-line treatment for patients with metastatic colorectal cancer. J BUON. 2009; 14:605-8.
    • (2009) J BUON. , vol.14 , pp. 605-608
    • Karacetin, D.1    Yalcin, B.2    Okten, B.3
  • 85
    • 77949261564 scopus 로고    scopus 로고
    • Phase II study of capecitabine plus oxaliplatin (XELOX) as first-line treatment and followed by maintenance of capecitabine in patients with metastatic colorectal cancer
    • Li YH, Luo HY, Wang FH et al. Phase II study of capecitabine plus oxaliplatin (XELOX) as first-line treatment and followed by maintenance of capecitabine in patients with metastatic colorectal cancer. J Cancer Res Clin Oncol. 2010; 136:503-10.
    • (2010) J Cancer Res Clin Oncol. , vol.136 , pp. 503-510
    • Li, Y.H.1    Luo, H.Y.2    Wang, F.H.3
  • 86
    • 22244477362 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin for the first-line treatment of elderly patients with metastatic colorectal carcinoma. Final results of the Southern Italy Cooperative Oncology Group trial 0108
    • Comella P, Natale D, Farris A et al. Capecitabine plus oxaliplatin for the first-line treatment of elderly patients with metastatic colorectal carcinoma. Final results of the Southern Italy Cooperative Oncology Group trial 0108. Cancer. 2005; 104:282-9.
    • (2005) Cancer , vol.104 , pp. 282-289
    • Comella, P.1    Natale, D.2    Farris, A.3
  • 87
    • 36248973681 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin (Xelox) in the treatment of chemotherapy-naïve patients with metastatic colorectal cancer
    • Yaman E, Uner A, Er O et al. Capecitabine plus oxaliplatin (Xelox) in the treatment of chemotherapy-naïve patients with metastatic colorectal cancer. Med Oncol. 2007; 24:431-5.
    • (2007) Med Oncol. , vol.24 , pp. 431-435
    • Yaman, E.1    Uner, A.2    Er, O.3
  • 88
    • 0036533777 scopus 로고    scopus 로고
    • Phase II study of capecitabine and oxaliplatin in first-line and second-line treatment of advanced or metastatic colorectal cancer
    • Borner MM, Dietrich D, Stupp R et al. Phase II study of capecitabine and oxaliplatin in first-line and second-line treatment of advanced or metastatic colorectal cancer. J Clin Oncol. 2002; 20:1759-66.
    • (2002) J Clin Oncol. , vol.20 , pp. 1759-1766
    • Borner, M.M.1    Dietrich, D.2    Stupp, R.3
  • 89
    • 0141725528 scopus 로고    scopus 로고
    • Phase II study of capecitabine and oxali-platin as first-line treatment in advanced colorectal cancer
    • Zeuli M, Nartdoni C, Pino MS et al. Phase II study of capecitabine and oxali-platin as first-line treatment in advanced colorectal cancer. Ann Oncol. 2003; 14:1378-82.
    • (2003) Ann Oncol. , vol.14 , pp. 1378-1382
    • Zeuli, M.1    Nartdoni, C.2    Pino, M.S.3
  • 90
    • 1642535368 scopus 로고    scopus 로고
    • Treatment of advanced colorectal carcinoma with oxaliplatin and capecitabine: A phase II trial
    • Shields AF, Zalupski MM, Marshall JL et al. Treatment of advanced colorectal carcinoma with oxaliplatin and capecitabine: a phase II trial. Cancer. 2004; 100:531-7.
    • (2004) Cancer , vol.100 , pp. 531-537
    • Shields, A.F.1    Zalupski, M.M.2    Marshall, J.L.3
  • 91
    • 0037837645 scopus 로고    scopus 로고
    • Randomized multicenter phase II trial of two different schedules of capecitabine plus oxaliplatin as first-line treatment in advanced colorectal cancer
    • Scheithauer W, Kornek GV, Raderer M et al. Randomized multicenter phase II trial of two different schedules of capecitabine plus oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol. 2003; 21:1307-12.
    • (2003) J Clin Oncol. , vol.21 , pp. 1307-1312
    • Scheithauer, W.1    Kornek, G.V.2    Raderer, M.3
  • 92
    • 35348908108 scopus 로고    scopus 로고
    • Two doses of oxaliplatin with capecitabine (XELOX) in metastatic colorectal cancer
    • Moreno-Solorzano I, Ibeas-Rollan R, Monzo-Planella M et al. Two doses of oxaliplatin with capecitabine (XELOX) in metastatic colorectal cancer. Clin Colorectal Cancer. 2007; 6:634-40.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 634-640
    • Moreno-Solorzano, I.1    Ibeas-Rollan, R.2    Monzo-Planella, M.3
  • 93
    • 45549100405 scopus 로고    scopus 로고
    • XELOX followed by XELIRI or the reverse sequence in advanced colorectal cancer
    • Sakar B, Gumus M, Basaran M et al. XELOX followed by XELIRI or the reverse sequence in advanced colorectal cancer. Oncology. 2007; 73:298-304.
    • (2007) Oncology , vol.73 , pp. 298-304
    • Sakar, B.1    Gumus, M.2    Basaran, M.3
  • 94
    • 49049105525 scopus 로고    scopus 로고
    • Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: Results of the TREE study
    • Hochster HS, Hart LL, Ramanathan RK et al. Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: results of the TREE study. J Clin Oncol. 2008; 26:3523-9.
    • (2008) J Clin Oncol. , vol.26 , pp. 3523-3529
    • Hochster, H.S.1    Hart, L.L.2    Ramanathan, R.K.3
  • 95
    • 42949150908 scopus 로고    scopus 로고
    • Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer
    • Cassidy J, Clarke S, Diaz-Rubio E et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol. 2008; 26:2006-12.
    • (2008) J Clin Oncol. , vol.26 , pp. 2006-2012
    • Cassidy, J.1    Clarke, S.2    Diaz-Rubio, E.3
  • 96
    • 34948857445 scopus 로고    scopus 로고
    • Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in meta-static colorectal cancer: A final report of the AIO Colorectal Study Group
    • Porschen R, Arkenau HT, Kubicka S et al. Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in meta-static colorectal cancer: a final report of the AIO Colorectal Study Group. J Clin Oncol. 2007; 25:4217-23.
    • (2007) J Clin Oncol. , vol.25 , pp. 4217-4223
    • Porschen, R.1    Arkenau, H.T.2    Kubicka, S.3
  • 97
    • 34948892881 scopus 로고    scopus 로고
    • Phase III study of capecitabine plus oxaliplatin compared with continuous infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: Final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial
    • Diaz-Rubio E, Tabernero J, Gomez-Espana A et al. Phase III study of capecitabine plus oxaliplatin compared with continuous infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial. J Clin Oncol. 2007; 25:4224-30.
    • (2007) J Clin Oncol. , vol.25 , pp. 4224-4230
    • Diaz-Rubio, E.1    Tabernero, J.2    Gomez-Espana, A.3
  • 98
    • 78649873169 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil-leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer
    • Ducreux M, Bennouna J, Hebbar M et al. Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil-leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer. Int J Cancer. 2011; 128:682-90.
    • (2011) Int J Cancer , vol.128 , pp. 682-690
    • Ducreux, M.1    Bennouna, J.2    Hebbar, M.3
  • 99
    • 33845210679 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin (xelox) versus protracted 5-fluorouracil venous infusion plus oxaliplatin (pvifox) as first-line treatment in advanced colorectal cancer: A GOAM phase II randomized study (FOCA trial)
    • Martoni AA, Pinto C, DiFabio F et al. Capecitabine plus oxaliplatin (xelox) versus protracted 5-fluorouracil venous infusion plus oxaliplatin (pvifox) as first-line treatment in advanced colorectal cancer: a GOAM phase II randomized study (FOCA trial). Eur J Cancer. 2006; 42:3161-8.
    • (2006) Eur J Cancer , vol.42 , pp. 3161-3168
    • Martoni, A.A.1    Pinto, C.2    DiFabio, F.3
  • 100
    • 31544438341 scopus 로고    scopus 로고
    • Short-time infusion of oxaliplatin in combination with capecitabine (XELOX) in patients with advanced colorectal cancer after failure to irinotecan and 5-fluorouracil
    • Pfeiffer P, Serbye H, Ehrsson H et al. Short-time infusion of oxaliplatin in combination with capecitabine (XELOX) in patients with advanced colorectal cancer after failure to irinotecan and 5-fluorouracil. Ann Oncol. 2006; 17:252-8.
    • (2006) Ann Oncol. , vol.17 , pp. 252-258
    • Pfeiffer, P.1    Serbye, H.2    Ehrsson, H.3
  • 101
    • 46249132910 scopus 로고    scopus 로고
    • Modified CAPOX (capecitabine plus oxaliplatin) regimen every two weeks as second-line treatment in patients with advanced colorectal cancer previously treated with irinotecan-based frontline therapy: A multicenter phase II study
    • Kakolyris S, Souglakos J, Polyzos A et al. Modified CAPOX (capecitabine plus oxaliplatin) regimen every two weeks as second-line treatment in patients with advanced colorectal cancer previously treated with irinotecan-based frontline therapy: a multicenter phase II study. Oncology. 2008; 74:31-6.
    • (2008) Oncology , vol.74 , pp. 31-36
    • Kakolyris, S.1    Souglakos, J.2    Polyzos, A.3
  • 102
    • 68949181503 scopus 로고    scopus 로고
    • Efficacy and safety of capecitabine and oxaliplatin combination as second-line treatment in advanced colorectal cancer
    • Heras P, Kritikos K, Hatzopoulos A et al. Efficacy and safety of capecitabine and oxaliplatin combination as second-line treatment in advanced colorectal cancer. Am J Ther. 2009; 16:319-22.
    • (2009) Am J Ther. , vol.16 , pp. 319-322
    • Heras, P.1    Kritikos, K.2    Hatzopoulos, A.3
  • 103
    • 53049092394 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: A randomized phase III non-inferiority study
    • Rothenberg ML, Cox JV, Butts C et al. Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III non-inferiority study. Ann Oncol. 2008; 19:1720-6.
    • (2008) Ann Oncol. , vol.19 , pp. 1720-1726
    • Rothenberg, M.L.1    Cox, J.V.2    Butts, C.3
  • 104
    • 58049194302 scopus 로고    scopus 로고
    • Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil-leucovorin in patients with metastatic colorectal cancer: A pooled analysis of randomized trials
    • Arkenau HT, Arnold D, Cassidy J et al. Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil-leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol. 2008; 26:5910-7.
    • (2008) J Clin Oncol. , vol.26 , pp. 5910-5917
    • Arkenau, H.T.1    Arnold, D.2    Cassidy, J.3
  • 105
    • 77958129436 scopus 로고    scopus 로고
    • Capecitabine/oxaliplatin as first-line treatment for metastatic colorectal cancer: A meta-analysis
    • Zhao G, Gao P, Yang KH et al. Capecitabine/oxaliplatin as first-line treatment for metastatic colorectal cancer: a meta-analysis. Colorectal Dis. 2010; 12:615-23.
    • (2010) Colorectal Dis. , vol.12 , pp. 615-623
    • Zhao, G.1    Gao, P.2    Yang, K.H.3
  • 106
    • 84863138482 scopus 로고    scopus 로고
    • Capecitabine plus oxalaplatin compared with 5-fluorouracil plus oxalaplatin in meta-static colorectal cancer: Meta-analysis of randomized controlled trials
    • Zhang C, Wang J, Gu H et al. Capecitabine plus oxalaplatin compared with 5-fluorouracil plus oxalaplatin in meta-static colorectal cancer: meta-analysis of randomized controlled trials. Oncol Lett. 2012; 3:831-8.
    • (2012) Oncol Lett. , vol.3 , pp. 831-838
    • Zhang, C.1    Wang, J.2    Gu, H.3
  • 107
    • 19944425122 scopus 로고    scopus 로고
    • First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil-leucovorin (FOLFOXIRI): Results of a phase II study with a simplified biweekly schedule
    • Masi G, Allegrini G, Cupini S et al. First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil-leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule. Ann Oncol. 2004; 15:1766-72.
    • (2004) Ann Oncol. , vol.15 , pp. 1766-1772
    • Masi, G.1    Allegrini, G.2    Cupini, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.