Endothelin-1 impairs angiogenesis in vitro through Rho-kinase activation after chronic intrauterine pulmonary hypertension in fetal sheep

Pediatric Research

Volumn 73, Issue 3, 2013, Pages 252-262

  Gien, Jason ^a,b   Tseng, Nancy ^a,b   Seedorf, Gregory ^a,b   Roe, Gates ^a,b   Abman, Steven H ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Children's Hospital Colorado   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN RECEPTOR; MESSENGER RNA; MONOCLONAL ANTIBODY; RHO KINASE; SMALL INTERFERING RNA;

ANGIOGENESIS; ANIMAL TISSUE; ARTERY LIGATION; ARTERY MUSCLE; ARTICLE; CELL LYSATE; CONTROLLED STUDY; DUCTUS ARTERIOSUS; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; FETUS; GENE EXPRESSION; IN VITRO STUDY; NONHUMAN; PERSISTENT PULMONARY HYPERTENSION; PRENATAL DISORDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PULMONARY ARTERY; RECEPTOR BLOCKING; SHEEP; WESTERN BLOTTING;

AMIDES; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; DNA PRIMERS; DUCTUS ARTERIOSUS; ENDOTHELIAL CELLS; ENDOTHELIN-1; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FETUS; HUMANS; INFANT, NEWBORN; LIGATION; LUNG; NEOVASCULARIZATION, PHYSIOLOGIC; PERSISTENT FETAL CIRCULATION SYNDROME; PYRIDINES; REAL-TIME POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; SHEEP;

EID: 84874073748     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2012.177     Document Type: Article

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