-
1
-
-
10744222390
-
Long-term treatment with a Rho-kinase inhibitor improves monocrotalineinduced fatal pulmonary hypertension in rats
-
Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, Hattori T, Nakashima Y, Kaibuchi K, Sueishi K, Takeshit A. Long-term treatment with a Rho-kinase inhibitor improves monocrotalineinduced fatal pulmonary hypertension in rats. Circ Res 94: 385-393, 2004.
-
(2004)
Circ Res
, vol.94
, pp. 385-393
-
-
Abe, K.1
Shimokawa, H.2
Morikawa, K.3
Uwatoku, T.4
Oi, K.5
Matsumoto, Y.6
Hattori, T.7
Nakashima, Y.8
Kaibuchi, K.9
Sueishi, K.10
Takeshit, A.11
-
2
-
-
33846110312
-
Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice
-
Abe K, Tawara S, Oi K, Hizume T, Uwatoku T, Fukumoto Y, Kaibuchi K, Shimokawa H. Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice. J Cardiovasc Pharmacol 48: 280-285, 2006.
-
(2006)
J Cardiovasc Pharmacol
, vol.48
, pp. 280-285
-
-
Abe, K.1
Tawara, S.2
Oi, K.3
Hizume, T.4
Uwatoku, T.5
Fukumoto, Y.6
Kaibuchi, K.7
Shimokawa, H.8
-
3
-
-
0033228503
-
Abnormal vasoreactivity in the pathophysiology of persistent pulmonary hypertension of the newborn
-
Abman SH. Abnormal vasoreactivity in the pathophysiology of persistent pulmonary hypertension of the newborn. Pediatr Rev 20: e103-e109, 1999.
-
(1999)
Pediatr Rev
, vol.20
-
-
Abman, S.H.1
-
4
-
-
34250671486
-
Recent advances in the pathogenesis and treatment of persistent pulmonary hypertension of the newborn
-
Abman SH. Recent advances in the pathogenesis and treatment of persistent pulmonary hypertension of the newborn. Neonatology 91: 283-290, 2007.
-
(2007)
Neonatology
, vol.91
, pp. 283-290
-
-
Abman, S.H.1
-
5
-
-
0024418107
-
Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation
-
Abman SH, Accurso FJ. Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation. Am J Physiol Heart Circ Physiol 257: H626-H634, 1989.
-
(1989)
Am J Physiol Heart Circ Physiol
, vol.257
-
-
Abman, S.H.1
Accurso, F.J.2
-
6
-
-
0025972986
-
Sustained fetal pulmonary vasodilation with prolonged atrial natriuretic factor and GMP infusions
-
Abman SH, Accurso FJ. Sustained fetal pulmonary vasodilation with prolonged atrial natriuretic factor and GMP infusions. Am J Physiol Heart Circ Physiol 260: H183-H192, 1991.
-
(1991)
Am J Physiol Heart Circ Physiol
, vol.260
-
-
Abman, S.H.1
Accurso, F.J.2
-
8
-
-
0022654649
-
Time-dependent response of fetal pulmonary blood flow to an increase in fetal oxygen tension
-
Accurso FJ, Alpert B, Wilkening RB, Petersen RG, Meschia G. Time-dependent response of fetal pulmonary blood flow to an increase in fetal oxygen tension. Respir Physiol 63: 43-52, 1986.
-
(1986)
Respir Physiol
, vol.63
, pp. 43-52
-
-
Accurso, F.J.1
Alpert, B.2
Wilkening, R.B.3
Petersen, R.G.4
Meschia, G.5
-
9
-
-
0028921751
-
The myogenic response of arterial vessels is increased in fetal pulmonary hypertension
-
Belik J. The myogenic response of arterial vessels is increased in fetal pulmonary hypertension. Pediatr Res 37: 196-201, 1995.
-
(1995)
Pediatr Res
, vol.37
, pp. 196-201
-
-
Belik, J.1
-
11
-
-
78651166541
-
The vascular resistance of the foetal and newly ventilated lung of the lamb
-
Cassin S, Dawes GS, Mott JC, Ross BB, Strang LB. The vascular resistance of the foetal and newly ventilated lung of the lamb. J Physiol 171: 61-79, 1964.
-
(1964)
J Physiol
, vol.171
, pp. 61-79
-
-
Cassin, S.1
Dawes, G.S.2
Mott, J.C.3
Ross, B.B.4
Strang, L.B.5
-
12
-
-
0026717373
-
Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus
-
Cornfield DN, Chatfield BA, McQueston JA, McMurtry IF, Abman SH. Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus. Am J Physiol Heart Circ Physiol 262: H1474-H1481, 1992.
-
(1992)
Am J Physiol Heart Circ Physiol
, vol.262
-
-
Cornfield, D.N.1
Chatfield, B.A.2
McQueston, J.A.3
McMurtry, I.F.4
Abman, S.H.5
-
13
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351: 95-105, 2000.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
14
-
-
73649173159
-
The vascular tone of the foetal lung
-
Dawes GS, Mott JC. The vascular tone of the foetal lung. J Physiol 164: 465-477, 1962.
-
(1962)
J Physiol
, vol.164
, pp. 465-477
-
-
Dawes, G.S.1
Mott, J.C.2
-
15
-
-
36349027680
-
2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats
-
2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats. Am J Physiol Lung Cell Mol Physiol 293: L1306-L1313, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Dhaliwal, J.S.1
Casey, D.B.2
Greco, A.J.3
Badejo Jr, A.M.4
Gallen, T.B.5
Murthy, S.N.6
Nossaman, B.D.7
Hyman, A.L.8
Kadowitz, P.J.9
-
16
-
-
0035800812
-
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms
-
Eto M, Kitazawa T, Yazawa M, Mukai H, Ono Y, Brautigan DL. Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms. J Biol Chem 276: 29072-29078, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 29072-29078
-
-
Eto, M.1
Kitazawa, T.2
Yazawa, M.3
Mukai, H.4
Ono, Y.5
Brautigan, D.L.6
-
17
-
-
4544388803
-
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase
-
Fagan KA, Oka M, Bauer NR, Gebb SA, Ivy DD, Morris KG, McMurtry IF. Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol 287: L656-L664, 2004.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Fagan, K.A.1
Oka, M.2
Bauer, N.R.3
Gebb, S.A.4
Ivy, D.D.5
Morris, K.G.6
McMurtry, I.F.7
-
18
-
-
14244260105
-
Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
-
Fukumoto Y, Matoba T, Ito A, Tanaka H, Kishi T, Hayashidani S, Abe K, Takeshita A, Shimokawa H. Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart 91: 391-392, 2005.
-
(2005)
Heart
, vol.91
, pp. 391-392
-
-
Fukumoto, Y.1
Matoba, T.2
Ito, A.3
Tanaka, H.4
Kishi, T.5
Hayashidani, S.6
Abe, K.7
Takeshita, A.8
Shimokawa, H.9
-
19
-
-
34247168120
-
Recent progress in the treatment of pulmonary arterial hypertension: Expectation for rho-kinase inhibitors
-
Fukumoto Y, Tawara S, Shimokawa H. Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors. Tohoku J Exp Med 211: 309-320, 2007.
-
(2007)
Tohoku J Exp Med
, vol.211
, pp. 309-320
-
-
Fukumoto, Y.1
Tawara, S.2
Shimokawa, H.3
-
20
-
-
28444461454
-
Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension
-
Guilluy C, Sauzeau V, Rolli-Derkinderen M, Guerin P, Sagan C, Pacaud P, Loirand G. Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension. Br J Pharmacol 146: 1010-1018, 2005.
-
(2005)
Br J Pharmacol
, vol.146
, pp. 1010-1018
-
-
Guilluy, C.1
Sauzeau, V.2
Rolli-Derkinderen, M.3
Guerin, P.4
Sagan, C.5
Pacaud, P.6
Loirand, G.7
-
21
-
-
31644431508
-
Beneficial acute effects of rho-kinase inhibitor in patients with pulmonary arterial hypertension
-
Ishikura K, Yamada N, Ito M, Ota S, Nakamura M, Isaka N, Nakano T. Beneficial acute effects of rho-kinase inhibitor in patients with pulmonary arterial hypertension. Circ J 70: 174-178, 2006.
-
(2006)
Circ J
, vol.70
, pp. 174-178
-
-
Ishikura, K.1
Yamada, N.2
Ito, M.3
Ota, S.4
Nakamura, M.5
Isaka, N.6
Nakano, T.7
-
22
-
-
0030482452
-
Endothelin blockade augments pulmonary vasodilation in the ovine fetus
-
Ivy DD, Kinsella JP, Abman SH. Endothelin blockade augments pulmonary vasodilation in the ovine fetus. J Appl Physiol 81: 2481-2487, 1996.
-
(1996)
J Appl Physiol
, vol.81
, pp. 2481-2487
-
-
Ivy, D.D.1
Kinsella, J.P.2
Abman, S.H.3
-
23
-
-
24644489945
-
Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension
-
Jarajapu YP, Knot HJ. Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension. Am J Physiol Heart Circ Physiol 289: H1917-H1922, 2005.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Jarajapu, Y.P.1
Knot, H.J.2
-
24
-
-
0036889864
-
Role of phospholipase C in development of myogenic tone in rat posterior cerebral arteries
-
Jarajapu YP, Knot HJ. Role of phospholipase C in development of myogenic tone in rat posterior cerebral arteries. Am J Physiol Heart Circ Physiol 283: H2234-H2238, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Jarajapu, Y.P.1
Knot, H.J.2
-
25
-
-
33847191058
-
Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats
-
Jiang BH, Tawara S, Abe K, Takaki A, Fukumoto Y, Shimokawa H. Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats. J Cardiovasc Pharmacol 49: 85-89, 2007.
-
(2007)
J Cardiovasc Pharmacol
, vol.49
, pp. 85-89
-
-
Jiang, B.H.1
Tawara, S.2
Abe, K.3
Takaki, A.4
Fukumoto, Y.5
Shimokawa, H.6
-
26
-
-
0024404382
-
Myogenic tone and reactivity: Definitions based on muscle physiology
-
Johansson B. Myogenic tone and reactivity: definitions based on muscle physiology. J Hypertens Suppl 7: S5-S9, 1989.
-
(1989)
J Hypertens Suppl
, vol.7
-
-
Johansson, B.1
-
27
-
-
0029069107
-
Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn
-
Kinsella JP, Abman SH. Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn. J Pediatr 126: 853-864, 1995.
-
(1995)
J Pediatr
, vol.126
, pp. 853-864
-
-
Kinsella, J.P.1
Abman, S.H.2
-
28
-
-
0032055663
-
2+] in cerebral arteries of rat by membrane potential and intravascular pressure
-
2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J Physiol 508: 199-209, 1998.
-
(1998)
J Physiol
, vol.508
, pp. 199-209
-
-
Knot, H.J.1
Nelson, M.T.2
-
29
-
-
0017178821
-
Persistent pulmonary hypertension of the newborn infant
-
Levin DL, Heymann MA, Kitterman JA, Gregory GA, Phibbs RH, Rudolph AM. Persistent pulmonary hypertension of the newborn infant. J Pediatr 89: 626-630, 1976.
-
(1976)
J Pediatr
, vol.89
, pp. 626-630
-
-
Levin, D.L.1
Heymann, M.A.2
Kitterman, J.A.3
Gregory, G.A.4
Phibbs, R.H.5
Rudolph, A.M.6
-
30
-
-
33846194678
-
Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats
-
Li F, Xia W, Li A, Zhao C, Sun R. Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats. Pharmacol Res 55: 64-71, 2007.
-
(2007)
Pharmacol Res
, vol.55
, pp. 64-71
-
-
Li, F.1
Xia, W.2
Li, A.3
Zhao, C.4
Sun, R.5
-
31
-
-
33646763902
-
Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology
-
Loirand G, Guerin P, Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ Res 98: 322-334, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 322-334
-
-
Loirand, G.1
Guerin, P.2
-
32
-
-
0036890302
-
Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists
-
Massett MP, Ungvari Z, Csiszar A, Kaley G, Koller A. Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists. Am J Physiol Heart Circ Physiol 283: H2282-H2287, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Massett, M.P.1
Ungvari, Z.2
Csiszar, A.3
Kaley, G.4
Koller, A.5
-
33
-
-
0037007054
-
Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina
-
Masumoto A, Mohri M, Shimokawa H, Urakami L, Usui M, Takeshita A. Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina. Circulation 105: 1545-1547, 2002.
-
(2002)
Circulation
, vol.105
, pp. 1545-1547
-
-
Masumoto, A.1
Mohri, M.2
Shimokawa, H.3
Urakami, L.4
Usui, M.5
Takeshita, A.6
-
34
-
-
33645957353
-
Signaling for contraction and relaxation in smooth muscle of the gut
-
Murthy KS. Signaling for contraction and relaxation in smooth muscle of the gut. Annu Rev Physiol 68: 345-374, 2006.
-
(2006)
Annu Rev Physiol
, vol.68
, pp. 345-374
-
-
Murthy, K.S.1
-
35
-
-
0041859740
-
i3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway
-
i3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. Biochem J 374: 145-155, 2003.
-
(2003)
Biochem J
, vol.374
, pp. 145-155
-
-
Murthy, K.S.1
Zhou, H.2
Grider, J.R.3
Brautigan, D.L.4
Eto, M.5
Makhlouf, G.M.6
-
36
-
-
33645816773
-
Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat
-
Nagaoka T, Gebb SA, Karoor V, Homma N, Morris KG, McMurtry IF, Oka M. Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat. J Appl Physiol 100: 996-1002, 2006.
-
(2006)
J Appl Physiol
, vol.100
, pp. 996-1002
-
-
Nagaoka, T.1
Gebb, S.A.2
Karoor, V.3
Homma, N.4
Morris, K.G.5
McMurtry, I.F.6
Oka, M.7
-
37
-
-
4544244944
-
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats
-
Nagaoka T, Morio Y, Casanova N, Bauer N, Gebb S, McMurtry I, Oka M. Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 287: L665-L672, 2004.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Nagaoka, T.1
Morio, Y.2
Casanova, N.3
Bauer, N.4
Gebb, S.5
McMurtry, I.6
Oka, M.7
-
38
-
-
34147189502
-
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
-
Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res 100: 923-929, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 923-929
-
-
Oka, M.1
Homma, N.2
Taraseviciene-Stewart, L.3
Morris, K.G.4
Kraskauskas, D.5
Burns, N.6
Voelkel, N.F.7
McMurtry, I.F.8
-
39
-
-
0027177730
-
Myogenic tone is coupled to phospholipase C and G protein activation in small cerebral arteries
-
Osol G, Laher I, Kelley M. Myogenic tone is coupled to phospholipase C and G protein activation in small cerebral arteries. Am J Physiol Heart Circ Physiol 265: H415-H420, 1993.
-
(1993)
Am J Physiol Heart Circ Physiol
, vol.265
-
-
Osol, G.1
Laher, I.2
Kelley, M.3
-
40
-
-
22444445227
-
Inhibition of 20-HETE abolishes the myogenic response during NOS antagonism in the ovine fetal pulmonary circulation
-
Parker TA, Grover TR, Kinsella JP, Falck JR, Abman SH. Inhibition of 20-HETE abolishes the myogenic response during NOS antagonism in the ovine fetal pulmonary circulation. Am J Physiol Lung Cell Mol Physiol 289: L261-L267, 2005.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
-
-
Parker, T.A.1
Grover, T.R.2
Kinsella, J.P.3
Falck, J.R.4
Abman, S.H.5
-
42
-
-
41549114170
-
Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle
-
Rattan S, Patel CA. Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle. Am J Physiol Gastrointest Liver Physiol 294: G687-G693, 2008.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Rattan, S.1
Patel, C.A.2
-
44
-
-
19044372537
-
Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery
-
Shiga N, Hirano K, Hirano M, Nishimura J, Nawata H, Kanaide H. Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery. Circ Res 96: 1014-1021, 2005.
-
(2005)
Circ Res
, vol.96
, pp. 1014-1021
-
-
Shiga, N.1
Hirano, K.2
Hirano, M.3
Nishimura, J.4
Nawata, H.5
Kanaide, H.6
-
45
-
-
0141751697
-
2+ sensitivity of smooth muscle and non-muscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
-
2+ sensitivity of smooth muscle and non-muscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83: 1325-1358, 2003.
-
(2003)
Physiol Rev
, vol.83
, pp. 1325-1358
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
46
-
-
0036086026
-
Chronic hypertension impairs flow-induced vasodilation and augments the myogenic response in fetal lung
-
Storme L, Parker TA, Kinsella JP, Rairigh RL, Abman SH. Chronic hypertension impairs flow-induced vasodilation and augments the myogenic response in fetal lung. Am J Physiol Lung Cell Mol Physiol 282: L56-L66, 2002.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.282
-
-
Storme, L.1
Parker, T.A.2
Kinsella, J.P.3
Rairigh, R.L.4
Abman, S.H.5
-
47
-
-
0032953090
-
In vivo evidence for a myogenic response in the fetal pulmonary circulation
-
Storme L, Rairigh RL, Parker TA, Kinsella JP, Abman SH. In vivo evidence for a myogenic response in the fetal pulmonary circulation. Pediatr Res 45: 425-431, 1999.
-
(1999)
Pediatr Res
, vol.45
, pp. 425-431
-
-
Storme, L.1
Rairigh, R.L.2
Parker, T.A.3
Kinsella, J.P.4
Abman, S.H.5
-
48
-
-
0013829435
-
The lungs at birth
-
Strang LB. The lungs at birth. Arch Dis Child 40: 575-582, 1965.
-
(1965)
Arch Dis Child
, vol.40
, pp. 575-582
-
-
Strang, L.B.1
|