메뉴 건너뛰기




Volumn 186, Issue 11, 2011, Pages 6568-6575

Endothelin-1 signaling promotes fibrosis in vitro in a bronchopulmonary dysplasia model by activating the extrinsic coagulation cascade

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIN 1; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN;

EID: 79958057011     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003756     Document Type: Article
Times cited : (38)

References (45)
  • 1
    • 67849130574 scopus 로고    scopus 로고
    • The many faces of tissue factor
    • Mackman, N. 2009. The many faces of tissue factor. J. Thromb. Haemost. 7 (Suppl 1): 136-139.
    • (2009) J. Thromb. Haemost. , vol.7 , Issue.SUPPL. 1 , pp. 136-139
    • Mackman, N.1
  • 4
    • 34948903311 scopus 로고    scopus 로고
    • Tissue factor: A link between C5a and neutrophil activation in antiphospholipid antibody-induced fetal injury
    • DOI 10.1182/blood-2007-01-070631
    • Redecha, P., R. Tilley, M. Tencati, J. E. Salmon, D. Kirchhofer, N. Mackman, and G. Girardi. 2007. Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood 110: 2423-2431. (Pubitemid 47523163)
    • (2007) Blood , vol.110 , Issue.7 , pp. 2423-2431
    • Redecha, P.1    Tilley, R.2    Tencati, M.3    Salmon, J.E.4    Kirchhofer, D.5    Mackman, N.6    Girardi, G.7
  • 5
    • 45849125000 scopus 로고    scopus 로고
    • Leptin induces the expression of functional tissue factor in human neutrophils and peripheral blood mononuclear cells through JAK2-dependent mechanisms and TNFalpha involvement
    • Rafail, S., K. Ritis, K. Schaefer, I. Kourtzelis, M. Speletas, M. Doumas, S. Giaglis, K. Kambas, S. Konstantinides, and G. Kartalis. 2008. Leptin induces the expression of functional tissue factor in human neutrophils and peripheral blood mononuclear cells through JAK2-dependent mechanisms and TNFalpha involvement. Thromb. Res. 122: 366-375.
    • (2008) Thromb. Res. , vol.122 , pp. 366-375
    • Rafail, S.1    Ritis, K.2    Schaefer, K.3    Kourtzelis, I.4    Speletas, M.5    Doumas, M.6    Giaglis, S.7    Kambas, K.8    Konstantinides, S.9    Kartalis, G.10
  • 7
    • 55849112296 scopus 로고    scopus 로고
    • Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome
    • Redecha, P., C. W. Franzke, W. Ruf, N. Mackman, and G. Girardi. 2008. Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J. Clin. Invest. 118: 3453-3461.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3453-3461
    • Redecha, P.1    Franzke, C.W.2    Ruf, W.3    Mackman, N.4    Girardi, G.5
  • 9
    • 21844455249 scopus 로고    scopus 로고
    • Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines
    • Szotowski, B., S. Antoniak, W. Poller, H. P. Schultheiss, and U. Rauch. 2005. Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines. Circ. Res. 96: 1233-1239.
    • (2005) Circ. Res. , vol.96 , pp. 1233-1239
    • Szotowski, B.1    Antoniak, S.2    Poller, W.3    Schultheiss, H.P.4    Rauch, U.5
  • 10
    • 0029033973 scopus 로고
    • Transcriptional regulation of tissue factor expression in human endothelial cells
    • Parry, G. C., and N. Mackman. 1995. Transcriptional regulation of tissue factor expression in human endothelial cells. Arterioscler. Thromb. Vasc. Biol. 15: 612-621.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 612-621
    • Parry, G.C.1    Mackman, N.2
  • 11
    • 0034795622 scopus 로고    scopus 로고
    • Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis
    • Howell, D. C., N. R. Goldsack, R. P. Marshall, R. J. McAnulty, R. Starke, G. Purdy, G. J. Laurent, and R. C. Chambers. 2001. Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis. Am. J. Pathol. 159: 1383-1395.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1383-1395
    • Howell, D.C.1    Goldsack, N.R.2    Marshall, R.P.3    McAnulty, R.J.4    Starke, R.5    Purdy, G.6    Laurent, G.J.7    Chambers, R.C.8
  • 12
    • 67649229153 scopus 로고    scopus 로고
    • Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway
    • Yu, C. C., M. J. Hsu, M. L. Kuo, R. F. Chen, M. C. Chen, K. J. Bai, M. C. Yu, B. C. Chen, and C. H. Lin. 2009. Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway. J. Immunol. 182: 7916-7927.
    • (2009) J. Immunol. , vol.182 , pp. 7916-7927
    • Yu, C.C.1    Hsu, M.J.2    Kuo, M.L.3    Chen, R.F.4    Chen, M.C.5    Bai, K.J.6    Yu, M.C.7    Chen, B.C.8    Lin, C.H.9
  • 13
    • 0030791559 scopus 로고    scopus 로고
    • Tissue factor expression and fibrin deposition in the lungs of patients with idiopathic pulmonary fibrosis and systemic sclerosis
    • Imokawa, S., A. Sato, H. Hayakawa, M. Kotani, T. Urano, and A. Takada. 1997. Tissue factor expression and fibrin deposition in the lungs of patients with idiopathic pulmonary fibrosis and systemic sclerosis. Am. J. Respir. Crit. Care Med. 156: 631-636.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 631-636
    • Imokawa, S.1    Sato, A.2    Hayakawa, H.3    Kotani, M.4    Urano, T.5    Takada, A.6
  • 14
    • 15544383094 scopus 로고    scopus 로고
    • The significance of cathepsins, thrombin and aminopeptidase in diffuse interstitial lung diseases
    • Kimura, M., K. Tani, J. Miyata, K. Sato, A. Hayashi, S. Otsuka, T. Urata, and S. Sone. 2005. The significance of cathepsins, thrombin and aminopeptidase in diffuse interstitial lung diseases. J. Med. Invest. 52: 93-100.
    • (2005) J. Med. Invest. , vol.52 , pp. 93-100
    • Kimura, M.1    Tani, K.2    Miyata, J.3    Sato, K.4    Hayashi, A.5    Otsuka, S.6    Urata, T.7    Sone, S.8
  • 17
    • 70350539686 scopus 로고    scopus 로고
    • Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts
    • Bogatkevich, G. S., A. Ludwicka-Bradley, and R. M. Silver. 2009. Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts. Arthritis Rheum. 60: 3455-3464.
    • (2009) Arthritis Rheum. , vol.60 , pp. 3455-3464
    • Bogatkevich, G.S.1    Ludwicka-Bradley, A.2    Silver, R.M.3
  • 19
    • 0023255397 scopus 로고
    • The progression of morphologic changes in bronchopulmonary dysplasia
    • Erickson, A. M., S. M. de la Monte, G. W. Moore, and G. M. Hutchins. 1987. The progression of morphologic changes in bronchopulmonary dysplasia. Am. J. Pathol. 127: 474-484.
    • (1987) Am. J. Pathol. , vol.127 , pp. 474-484
    • Erickson, A.M.1    De La Monte, S.M.2    Moore, G.W.3    Hutchins, G.M.4
  • 20
    • 0034775357 scopus 로고    scopus 로고
    • Early activation of inflammation and clotting in the preterm lamb with neonatal RDS: Comparison of conventional ventilation and high frequency oscillatory ventilation
    • Jaarsma, A. S., M. A. Braaksma, W. B. Geven, W. Van Oeveren, and S. B. Oetomo. 2001. Early activation of inflammation and clotting in the preterm lamb with neonatal RDS: comparison of conventional ventilation and high frequency oscillatory ventilation. Pediatr. Res. 50: 650-657.
    • (2001) Pediatr. Res. , vol.50 , pp. 650-657
    • Jaarsma, A.S.1    Braaksma, M.A.2    Geven, W.B.3    Van Oeveren, W.4    Oetomo, S.B.5
  • 21
    • 0019780799 scopus 로고
    • Cytologic evaluation of pulmonary effluent in neonates with respiratory distress syndrome and bronchopulmonary dysplasia
    • Merritt, T. A., J. M. Puccia, and I. D. Stuard. 1981. Cytologic evaluation of pulmonary effluent in neonates with respiratory distress syndrome and bronchopulmonary dysplasia. Acta Cytol. 25: 631-639.
    • (1981) Acta Cytol. , vol.25 , pp. 631-639
    • Merritt, T.A.1    Puccia, J.M.2    Stuard, I.D.3
  • 23
    • 0030038943 scopus 로고    scopus 로고
    • Elevated cytokine levels in tracheobronchial aspirate fluids from ventilator treated neonates with bronchopulmonary dysplasia
    • Tullus, K., G. W. Noack, L. G. Burman, R. Nilsson, B. Wretlind, and A. Brauner. 1996. Elevated cytokine levels in tracheobronchial aspirate fluids from ventilator treated neonates with bronchopulmonary dysplasia. Eur. J. Pediatr. 155: 112-116.
    • (1996) Eur. J. Pediatr. , vol.155 , pp. 112-116
    • Tullus, K.1    Noack, G.W.2    Burman, L.G.3    Nilsson, R.4    Wretlind, B.5    Brauner, A.6
  • 24
    • 0029903217 scopus 로고    scopus 로고
    • Increase in interleukin (IL)-1 beta and IL-6 in bronchoalveolar lavage fluid obtained from infants with chronic lung disease of prematurity
    • Kotecha, S., L. Wilson, A. Wangoo, M. Silverman, and R. J. Shaw. 1996. Increase in interleukin (IL)-1 beta and IL-6 in bronchoalveolar lavage fluid obtained from infants with chronic lung disease of prematurity. Pediatr. Res. 40: 250-256.
    • (1996) Pediatr. Res. , vol.40 , pp. 250-256
    • Kotecha, S.1    Wilson, L.2    Wangoo, A.3    Silverman, M.4    Shaw, R.J.5
  • 25
    • 0030731406 scopus 로고    scopus 로고
    • Elevation of interleukin-8 and interleukin-6 precedes the influx of neutrophils in tracheal aspirates from preterm infants who develop bronchopulmonary dysplasia
    • Munshi, U. K., J. O. Niu, M. M. Siddiq, and L. A. Parton. 1997. Elevation of interleukin-8 and interleukin-6 precedes the influx of neutrophils in tracheal aspirates from preterm infants who develop bronchopulmonary dysplasia. Pediatr. Pulmonol. 24: 331-336.
    • (1997) Pediatr. Pulmonol. , vol.24 , pp. 331-336
    • Munshi, U.K.1    Niu, J.O.2    Siddiq, M.M.3    Parton, L.A.4
  • 26
    • 0031865750 scopus 로고    scopus 로고
    • Early increase in endothelin-1 in tracheal aspirates of preterm infants: Correlation with bronchopulmonary dysplasia
    • Niu, J. O., U. K. Munshi, M. M. Siddiq, and L. A. Parton. 1998. Early increase in endothelin-1 in tracheal aspirates of preterm infants: correlation with bronchopulmonary dysplasia. J. Pediatr. 132: 965-970.
    • (1998) J. Pediatr. , vol.132 , pp. 965-970
    • Niu, J.O.1    Munshi, U.K.2    Siddiq, M.M.3    Parton, L.A.4
  • 28
    • 73949159217 scopus 로고    scopus 로고
    • Potential role of endothelin-1 in pulmonary fibrosis: From the bench to the clinic
    • Ross, B., P. D'Orléans-Juste, and A. Giaid. 2010. Potential role of endothelin-1 in pulmonary fibrosis: from the bench to the clinic. Am. J. Respir. Cell Mol. Biol. 42: 16-20.
    • (2010) Am. J. Respir. Cell Mol. Biol. , vol.42 , pp. 16-20
    • Ross, B.1    D'Orléans-Juste, P.2    Giaid, A.3
  • 29
    • 14844292619 scopus 로고    scopus 로고
    • Role of endothelin in fibrosis and anti-fibrotic potential of bosentan
    • Clozel, M., and H. Salloukh. 2005. Role of endothelin in fibrosis and anti-fibrotic potential of bosentan. Ann. Med. 37: 2-12.
    • (2005) Ann. Med. , vol.37 , pp. 2-12
    • Clozel, M.1    Salloukh, H.2
  • 32
    • 26844434058 scopus 로고    scopus 로고
    • The chemokines CXCL9, CXCL10, and CXCL11 differentially stimulate G alpha i-independent signaling and actin responses in human intestinal myofibroblasts
    • Kouroumalis, A., R. J. Nibbs, H. Aptel, K. L. Wright, G. Kolios, and S. G. Ward. 2005. The chemokines CXCL9, CXCL10, and CXCL11 differentially stimulate G alpha i-independent signaling and actin responses in human intestinal myofibroblasts. J. Immunol. 175: 5403-5411.
    • (2005) J. Immunol. , vol.175 , pp. 5403-5411
    • Kouroumalis, A.1    Nibbs, R.J.2    Aptel, H.3    Wright, K.L.4    Kolios, G.5    Ward, S.G.6
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 36
    • 0037215667 scopus 로고    scopus 로고
    • Thrombin contributes to bronchoalveolar lavage fluid mitogenicity in lung disease of the premature infant
    • Dik, W. A., L. J. Zimmermann, B. A. Naber, D. J. Janssen, A. H. van Kaam, and M. A. Versnel. 2003. Thrombin contributes to bronchoalveolar lavage fluid mitogenicity in lung disease of the premature infant. Pediatr. Pulmonol. 35: 34-41.
    • (2003) Pediatr. Pulmonol. , vol.35 , pp. 34-41
    • Dik, W.A.1    Zimmermann, L.J.2    Naber, B.A.3    Janssen, D.J.4    Van Kaam, A.H.5    Versnel, M.A.6
  • 37
    • 77955883153 scopus 로고    scopus 로고
    • Complement: A key system for immune surveillance and homeostasis
    • Ricklin, D., G. Hajishengallis, K. Yang, and J. D. Lambris. 2010. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 11: 785-797.
    • (2010) Nat. Immunol. , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 39
    • 34447565024 scopus 로고    scopus 로고
    • Different profiles of Ca2+ responses to endothelin-1 and PDGF in liver myofibroblasts during the process of cell differentiation
    • Kojima, N., M. Hori, T. Murata, Y. Morizane, and H. Ozaki. 2007. Different profiles of Ca2+ responses to endothelin-1 and PDGF in liver myofibroblasts during the process of cell differentiation. Br. J. Pharmacol. 151: 816-827.
    • (2007) Br. J. Pharmacol. , vol.151 , pp. 816-827
    • Kojima, N.1    Hori, M.2    Murata, T.3    Morizane, Y.4    Ozaki, H.5
  • 40
    • 74949123200 scopus 로고    scopus 로고
    • Microvascular thrombosis and multiple organ dysfunction syndrome
    • Gando, S. 2010. Microvascular thrombosis and multiple organ dysfunction syndrome. Crit. Care Med. 38(2 Suppl):S35-S42.
    • (2010) Crit. Care Med. , vol.38 , Issue.2 SUPPL.
    • Gando, S.1
  • 41
    • 0033258181 scopus 로고    scopus 로고
    • Enhanced insulin-like growth factor binding protein-related protein 2 (connective tissue growth factor) expression in patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis
    • Allen, J. T., R. A. Knight, C. A. Bloor, and M. A. Spiteri. 1999. Enhanced insulin-like growth factor binding protein-related protein 2 (connective tissue growth factor) expression in patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis. Am. J. Respir. Cell Mol. Biol. 21: 693-700.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.21 , pp. 693-700
    • Allen, J.T.1    Knight, R.A.2    Bloor, C.A.3    Spiteri, M.A.4
  • 42
    • 35448988114 scopus 로고    scopus 로고
    • Molecular targets in pulmonary fibrosis: The myofibroblast in focus
    • DOI 10.1378/chest.06-2568
    • Scotton, C. J., and R. C. Chambers. 2007. Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Chest 132: 1311-1321. (Pubitemid 47621009)
    • (2007) Chest , vol.132 , Issue.4 , pp. 1311-1321
    • Scotton, C.J.1    Chambers, R.C.2
  • 43
    • 2542485410 scopus 로고    scopus 로고
    • Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts
    • Shi-Wen, X., Y. Chen, C. P. Denton, M. Eastwood, E. A. Renzoni, G. Bou-Gharios, J. D. Pearson, M. Dashwood, R. M. du Bois, C. M. Black, et al. 2004. Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. Mol. Biol. Cell 15: 2707-2719.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2707-2719
    • Shi-Wen, X.1    Chen, Y.2    Denton, C.P.3    Eastwood, M.4    Renzoni, E.A.5    Bou-Gharios, G.6    Pearson, J.D.7    Dashwood, M.8    Du Bois, R.M.9    Black, C.M.10
  • 44
    • 0029585975 scopus 로고
    • Organization of the gene encoding the human endothelin-converting enzyme (ECE-1)
    • Valdenaire, O., E. Rohrbacher, and M. G. Mattei. 1995. Organization of the gene encoding the human endothelin-converting enzyme (ECE-1). J. Biol. Chem. 270: 29794-29798.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29794-29798
    • Valdenaire, O.1    Rohrbacher, E.2    Mattei, M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.