TSH and free triiodothyronine concentrations are associated with weight loss in a lifestyle intervention and weight regain afterwards in obese children

European Journal of Endocrinology

Volumn 168, Issue 3, 2013, Pages 323-329

  Wolters, Barbara ^a   Lass, Nina ^a   Reinehr, Thomas ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; THYROTROPIN; THYROXINE;

ARTICLE; BODY MASS; CHILD; CLINICAL EFFECTIVENESS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FREE LIOTHYRONINE INDEX; HORMONE DETERMINATION; HUMAN; LIFESTYLE MODIFICATION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBESITY; PRESCHOOL CHILD; PRIORITY JOURNAL; PUBERTY; THERAPY EFFECT; WEIGHT GAIN; WEIGHT REDUCTION;

ADOLESCENT; BODY MASS INDEX; CHILD; CHILD DEVELOPMENT; DIET, REDUCING; EXERCISE; FEMALE; FOLLOW-UP STUDIES; GERMANY; HUMANS; LIFE STYLE; LONGITUDINAL STUDIES; MALE; OBESITY; RECURRENCE; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE; WEIGHT GAIN; WEIGHT LOSS;

EID: 84874051802     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-12-0981     Document Type: Article

References (34)

1. Reinehr T. Obesity and thyroid function. Molecular and Cellular Endocrinology 2010 316 165-171. (doi:10.1016/j.mce.2009. 06.005)
2. Reinehr T. Thyroid function in the nutritionally obese child and adolescent. Current Opinion in Pediatrics 2011 23 415-420. (doi:10.1097/MOP. 0b013e328344c393)
3. Shalitin S, Yackobovitch-Gavan M & Phillip M. Prevalence of thyroid dysfunction in obese children and adolescents before and after weight reduction and its relation to other metabolic parameters. Hormone Research 2009 71 155-161. (doi:10.1159/000197872)
4. Marras V, Casini MR, Pilia S, Carta D., Civolani P, Porcu M, Uccheddu AP & Loche S. Thyroid function in obese children and adolescents. Hormone Research in Paediatrics 2010 73 193-197. (doi:10.1159/000284361)
5. Dekelbab BH, Abou Ouf HA & Jain I. Prevalence of elevated thyroid-stimulating hormone levels in obese children and adolescents. Endocrine Practice 2010 16 187-190. (doi:10.4158/EP09176.OR)
6. Grandone A, Santoro N, Coppola F., Calabro P, Perrone L & Del Giudice EM. Thyroid function derangement and childhood obesity: an Italian experience. BMC Endocrine Disorders 2010 10 8. (doi:10.1186/1472-6823-10-8)
7. Reinehr T, de Sousa G & Andler W. Hyperthyrotropinemia in obese children is reversible after weight loss and is not related to lipids. Journal of Clinical Endocrinology and Metabolism 2006 91 3088-3091. (doi:10.1210/jc. 2006-0095)
8. Reinehr T, Isa A, de Sousa G, Dieffenbach R & Andler W. Thyroid hormones and their relation to weight status. Hormone Research 2008 70 51-57. (doi:10.1159/000129678)
9. Rotondi M, Leporati P, La Manna A, Pirali B, Mondello T., Fonte R, Magri F & Chiovato L. Raised serum TSH levels in patients with morbid obesity: is it enough to diagnose subclinical hypothyroidism? European Journal of Endocrinology 2009 160 403-408. (doi:10.1530/EJE-08-0734)
10. Reinehr T & Andler W. Thyroid hormones before and after weight loss in obesity. Archives of Disease in Childhood 2002 87 320-323. (doi:10.1136/adc.87.4.320)
11. Sari R, Balci MK, Altunbas H & Karayalcin U. The effect of body weight and weight loss on thyroid volume and function in obese women. Clinical Endocrinology 2003 59 258-262. (doi:10.1046/j. 1365-2265.2003.01836.x)
12. Rotondi M, Magri F & Chiovato L. Thyroid and obesity: not a oneway interaction. Journal of Clinical Endocrinology and Metabolism 2011 96 344-346. (doi:10.1210/jc.2010-2515)
13. Knudsen N, Laurberg P, Rasmussen L.B., Bülow I, Perrild H., Ovesen L & Jørgensen T. Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population. Journal of Clinical Endocrinology and Metabolism 2005 90 4019-4024. (doi:10.1210/jc.2004-2225)
14. Legradi G, Emerson CH, Ahima R.S., Flier JS & Lechan RM. Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology 1997 138 2569-2576. (doi:10.1210/en.138.6.2569)
15. Rapa A, Monzani A, Moia S., Vivenza D, Bellone S, Petri A., Teofoli F, Cassio A, Cesaretti G., Corrias A et al. Subclinical hypothyroidism in children and adolescents: a wide range of clinical, biochemical, and genetic factors involved. Journal of Clinical Endocrinology and Metabolism 2009 94 2414-2420. (doi:10.1210/jc.2009-0375)
16. Radetti G, Kleon W, Buzi F., Crivellaro C, Pappalardo L, di Iorgi N & Maghnie M. Thyroid function and structure are affected in childhood obesity. Journal of Clinical Endocrinology and Metabolism 2008 93 4749-4754. (doi:10.1210/jc.2008-0823)
17. Cole TJ. The LMS method for constructing normalized growth standards. European Journal of Clinical Nutrition 1990 44 45-60.
18. Cole TJ, Bellizzi MC, Flegal KM & Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000 320 1240-1243. (doi:10.1136/bmj. 320.7244.1240)
19. Kromeyer-Hauschild K., Wabitsch M, Kunze D., Geller F, Geiß HC, Hesse V, von Hippel A, Jaeger U, Johnsen D, Korte W et al. Percentiles of body mass index in children and adolescents evaluated from different regional German studies. Monatsschrift für Kinderheilkunde 2001 149 807-818. (doi:10.1007/s00 1120170107)
20. Reinehr T, Kersting M, Wollenhaupt A., Alexy U, Kling B, Ströbele K & Andler W. Evaluation of the training program "OBELDICKS" for obese children and adolescents. Klinische Padiatrie 2005 217 1-8. (doi:10.1055/s-2004-816246)
21. Reinehr T, Temmesfeld M, Kersting M., de Sousa G & Toschke AM. Four-year follow-up of children and adolescents participating in an obesity intervention program. International Journal of Obesity 2007 31 1074-1077. (doi:10.1038/sj.ijo.0803637)
22. Wunsch R, de Sousa G, Toschke AM & Reinehr T. Intima-media thickness in obese children before and after weight loss. Pediatrics 2006 118 2334-2340. (doi:10.1542/peds.2006-0302)
23. Reinehr T, Kiess W, Kapellen T & Andler W. Insulin sensitivity among obese children and adolescents, according to degree of weight loss. Pediatrics 2004 114 1569-1573. (doi:10.1542/peds. 2003-0649-F)
24. Pacifico L, Anania C, Ferraro F., Andreoli GM & Chiesa C. Thyroid function in childhood obesity and metabolic comorbidity. Clinica Chimica Acta 2012 413 396-405. (doi:10.1016/j.cca.2011.11. 013)
25. Blennemann B, Leahy P, Kim TS & Freake HC. Tissue-specific regulation of lipogenic mRNAs by thyroid hormone. Molecular and Cellular Endocrinology 1995 110 1-8. (doi:10.1016/0303-7207(95)03509-6)
26. Roti E, Minelli R & Salvi M. Thyroid hormone metabolism in obesity. International Journal of Obesity and Related Metabolic Disorders 2000 24 (Suppl 2) S113-S115. (doi:10.1038/sj.ijo. 0801293)
27. Shin DJ & Osborne TF. Thyroid hormone regulation and cholesterol metabolism are connected through sterol regulatory element-binding protein-2 (SREBP-2). Journal of Biological Chemistry 2003 278 34114-34118. (doi:10.1074/jbc.M305417200)
28. Silva JE. The thermogenic effect of thyroid hormone and its clinical implications. Annals of Internal Medicine 2003 139 205-213.
29. Kiortsis DN, Durack I & Turpin G. Effects of a low-calorie diet on resting metabolic rate and serum tri-iodothyronine levels in obese children. European Journal of Pediatrics 1999 158 446-450. (doi:10.1007/s004310051117)
30. Heshka S, Yang MU, Wang J, Burt P & Pi-Sunyer FX. Weight loss and change in resting metabolic rate. American Journal of Clinical Nutrition 1990 52 981-986.
31. Hill JO, Sparling PB, Shields TW & Heller PA. Effects of exercise and food restriction on body composition and metabolic rate in obese women. American Journal of Clinical Nutrition 1987 46 622-630.
32. al-Adsani H., Hoffer LJ & Silva JE. Resting energy expenditure is sensitive to small dose changes in patients on chronic thyroid hormone replacement. Journal of Clinical Endocrinology and Metabolism 1997 82 1118-1125. (doi:10.1210/jc.82.4.1118)
33. Santini F, Pinchera A, Marsili A., Ceccarini G, Castagna MG, Valeriano R, Giannetti M., Taddei D, Centoni R, Scartabelli G et al. Lean body mass is a major determinant of levothyroxine dosage in the treatment of thyroid diseases. Journal of Clinical Endocrinology and Metabolism 2005 90 124-127. (doi:10.1210/jc.2004-1306)
34. Katzeff HL & Selgrad C. Maintenance of thyroid hormone production during exercise-induced weight loss. American Journal of Physiology 1991 261 E382-E388.