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Volumn 13, Issue 6, 2012, Pages 2563-2569

Chemopreventive efficacy of Moringa oleifera pods against 7, 12-dimethylbenz[a]anthracene induced hepatic carcinogenesis in mice

Author keywords

7 12 Dimethylbenz a anthracene; Hepato protective; M. Oleifera; Oxidative stress; Xenobiotic

Indexed keywords


EID: 84874034580     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.6.2563     Document Type: Article
Times cited : (41)

References (46)
  • 1
    • 33745959003 scopus 로고    scopus 로고
    • Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability
    • Arabshahi DS, Devi V, Urooj A (2007). Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability. Food Chem, 100, 1100-5.
    • (2007) Food Chem , vol.100 , pp. 1100-1105
    • Arabshahi, D.S.1    Devi, V.2    Urooj, A.3
  • 2
    • 0038012782 scopus 로고    scopus 로고
    • Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L
    • Bennett RN, Mellon FA, Foidl N, et al(2003). Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (Horseradish tree) and Moringa stenopetala L. J Agri Food Chem, 51, 3546-53.
    • (2003) (Horseradish tree) and Moringa stenopetala L. J Agri Food Chem , vol.51 , pp. 3546-3553
    • Bennett, R.N.1    Mellon, F.A.2    Foidl, N.3
  • 3
    • 0142245495 scopus 로고    scopus 로고
    • Chemomodulatory effect of Moringa oleifera, Lam. on hepatic carcinogen metabolizing enzymes, antioxidant parameters and skin papillomagenesis in mice
    • Bharali R, Tabassum J, Azad MRH (2003). Chemomodulatory effect of Moringa oleifera, Lam. on hepatic carcinogen metabolizing enzymes, antioxidant parameters and skin papillomagenesis in mice. Asian Pac J Cancer Prev, 4, 131-9.
    • (2003) Asian Pac J Cancer Prev , vol.4 , pp. 131-139
    • Bharali, R.1    Tabassum, J.2    Azad, M.R.H.3
  • 5
    • 0242468790 scopus 로고    scopus 로고
    • Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract: part II
    • Chattopadhyay RR (2003). Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract: part II. J of Ethnopharmacol, 89, 217-9.
    • (2003) J of Ethnopharmacol , vol.89 , pp. 217-219
    • Chattopadhyay, R.R.1
  • 7
    • 0029932363 scopus 로고    scopus 로고
    • Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease
    • De Leve LD, Wang X, Kuhlenkamp JF, et al(1996). Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease. Hepatol, 23, 589-99.
    • (1996) Hepatol , vol.23 , pp. 589-599
    • De Leve, L.D.1    Wang, X.2    Kuhlenkamp, J.F.3
  • 8
    • 47149118870 scopus 로고    scopus 로고
    • Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level
    • Fakurazi S, Hairuszah I, Nanthini U (2008). Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level. Food & Chemical Toxicol, 46, 2611-5.
    • (2008) Food and Chemical Toxicol , vol.46 , pp. 2611-2615
    • Fakurazi, S.1    Hairuszah, I.2    Nanthini, U.3
  • 10
    • 0032922382 scopus 로고    scopus 로고
    • An antitumor promoter from Moringa oleifera Lam
    • Guevara AP, Vargas C, Sakurai H, et al(1999). An antitumor promoter from Moringa oleifera Lam. Mut Res, 440, 181-8.
    • (1999) Mut Res , vol.440 , pp. 181-188
    • Guevara, A.P.1    Vargas, C.2    Sakurai, H.3
  • 12
    • 34047197149 scopus 로고
    • Some Polycyclic Aromatic Hydrocarbons and Heterocyclic Compounds
    • IARC. Lyon, France: International Agency for Research on Cancer
    • IARC. 1973. Some Polycyclic Aromatic Hydrocarbons and Heterocyclic Compounds. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, vol. 3. Lyon, France: International Agency for Research on Cancer. pp 271.
    • (1973) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans , vol.3 , pp. 271
  • 13
    • 0021007163 scopus 로고
    • Polynuclear Aromatic Compounds, Part 1
    • IARC Chemical, Environmental and Experimental Data. Lyon, France: International Agency for Research on Cancer
    • IARC (1983). Polynuclear Aromatic Compounds, Part 1. Chemical, Environmental and Experimental Data. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, vol. 32. Lyon, France: International Agency for Research on Cancer.
    • (1983) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans , vol.32
  • 14
    • 0003173565 scopus 로고
    • Polynuclear Aromatic Compounds, Part 3. Industrial Exposures in Aluminum Production, Coal Gasification, Coke Production, and Iron and Steel Founding
    • Lyon, France: International Agency for Research on Cancer.IARC
    • IARC (1984). Polynuclear Aromatic Compounds, Part 3. Industrial Exposures in Aluminum Production, Coal Gasification, Coke Production, and Iron and Steel Founding. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, vol. 34. Lyon, France: International Agency for Research on Cancer. 219 pp.
    • (1984) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans , vol.34 , pp. 219
  • 15
    • 0021951738 scopus 로고
    • Polynuclear Aromatic 4. Bitumens, Coal Tars and Derived Products, Shale Oils and Soots
    • Lyon, France: International Agency for Research on Cancer. IARC
    • IARC (1985). Polynuclear Aromatic 4. Bitumens, Coal Tars and Derived Products, Shale Oils and Soots. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, vol. 35. Lyon, France: International Agency for Research on Cancer. 271 pp.
    • (1985) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans , vol.35 , pp. 271
  • 16
    • 9644286401 scopus 로고
    • Overall Evaluations of Carcinogenicity
    • Lyon, France: International Agency for Research on Cancer. IARC
    • IARC (1987). Overall Evaluations of Carcinogenicity. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, Supplement 7. Lyon, France: International Agency for Research on Cancer. 440 pp.
    • (1987) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans , Issue.SUPPL. 7 , pp. 440
  • 18
    • 79958856603 scopus 로고    scopus 로고
    • Chemopreventive effect of hydroethanolic extract of Euphorbia neriifolia leaves against DENA-induced renal carcinogenesis in mice
    • Janmeda P, Sharma V, Singh L, et al(2011). Chemopreventive effect of hydroethanolic extract of Euphorbia neriifolia leaves against DENA-induced renal carcinogenesis in mice. APJCP, 12, 677-83.
    • (2011) APJCP , vol.12 , pp. 677-683
    • Janmeda, P.1    Sharma, V.2    Singh, L.3
  • 19
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis. Protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic intermediate
    • Jollow DJ, Mitchell JR, Zampagilone N et al(1974). Bromobenzene induced liver necrosis. Protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic intermediate. Pharmacol, 11, 151-69.
    • (1974) Pharmacol , vol.11 , pp. 151-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampagilone, N.3
  • 20
    • 0031665666 scopus 로고    scopus 로고
    • Glutathione-S-trensferase and prevention of cellular free radical damage
    • Kettrer B (1998). Glutathione-S-trensferase and prevention of cellular free radical damage. Free Rad Res, 28, 647-58.
    • (1998) Free Rad Res , vol.28 , pp. 647-658
    • Kettrer, B.1
  • 21
    • 0345708284 scopus 로고    scopus 로고
    • Antioxidant action of Moringa oleifera Lam (drumstick) against antitubercular drugs induced lipid peroxidation in rats
    • Kumar A, Pari L (2003). Antioxidant action of Moringa oleifera Lam (drumstick) against antitubercular drugs induced lipid peroxidation in rats. J Med Food, 6, 255-9.
    • (2003) J Med Food , vol.6 , pp. 255-259
    • Kumar, A.1    Pari, L.2
  • 22
    • 0036649448 scopus 로고    scopus 로고
    • Extraction and identification of natural antioxidants from the seeds of Moringa oleifera tree variety of Malavi
    • Lalas S, Tsaknis J (2002). Extraction and identification of natural antioxidants from the seeds of Moringa oleifera tree variety of Malavi. J Am Oil Chem Soc, 79, 677-83.
    • (2002) J Am Oil Chem Soc , vol.79 , pp. 677-683
    • Lalas, S.1    Tsaknis, J.2
  • 23
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • Lowry OH, Rosebrough NJ, Farr AL, et al (1951). Protein measurement with the Folin phenol reagent. J Biol Chem, 193, 265-75.
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3
  • 24
    • 0021154323 scopus 로고
    • Differerential distribution of glutathione and glutathione related enzymes in rabbit kidney
    • Mohandas J, Marshall JJ, Duggin GG, et al(1984). Differerential distribution of glutathione and glutathione related enzymes in rabbit kidney. Biochem Pharmacol, 33, 1801-7.
    • (1984) Biochem Pharmacol , vol.33 , pp. 1801-1807
    • Mohandas, J.1    Marshall, J.J.2    Duggin, G.G.3
  • 25
    • 0030781755 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: clinicopathological aspects
    • Okuda K (1997). Hepatocellular carcinoma: clinicopathological aspects. J Gastroenterol Hepatol, 2, 314-8.
    • (1997) J Gastroenterol Hepatol , vol.2 , pp. 314-318
    • Okuda, K.1
  • 26
    • 78651165715 scopus 로고
    • The carbon monoxide binding pigment of liver
    • Omura T, Sato R (1964). The carbon monoxide binding pigment of liver. J Biol Chem, 239, 2370-8.
    • (1964) J Biol Chem , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 27
    • 84856566247 scopus 로고    scopus 로고
    • A Review on horse radish tree (moringa oleifera): a multipurpose tree with high economic and commercial importance
    • Paliwal R, Sharma V, Pracheta (2011a). A Review on horse radish tree (moringa oleifera): a multipurpose tree with high economic and commercial importance. Asian J Biotechnol, 3, 317-28.
    • (2011) Asian J Biotechnol , vol.3 , pp. 317-328
    • Paliwal, R.1    Sharma, V.2    Pracheta, X.3
  • 28
    • 79958807853 scopus 로고    scopus 로고
    • Antinephrotoxic effect of administration of moringa oleifera lam in amelioration of DMBA-induced renal carcinogenesis in Swiss albino mice
    • Paliwal R, Sharma V, Pracheta, et al(2011b). Antinephrotoxic effect of administration of moringa oleifera lam in amelioration of DMBA-induced renal carcinogenesis in Swiss albino mice. Biol med, 3, 27-35.
    • (2011) Biol med , vol.3 , pp. 27-35
    • Paliwal, R.1    Sharma, V.2    Pracheta, X.3
  • 29
    • 83055174095 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant potential of moringa oleifera pods against DMBA-induced hepatocarcinogenesis in male mice
    • Paliwal R, Sharma V, Pracheta, et al(2011c). Hepatoprotective and antioxidant potential of moringa oleifera pods against DMBA-induced hepatocarcinogenesis in male mice. Int J Drug Dev Res, 3, 128-38.
    • (2011) Int J Drug Dev Res , vol.3 , pp. 128-138
    • Paliwal, R.1    Sharma, V.2    Pracheta, X.3
  • 30
    • 84863393831 scopus 로고    scopus 로고
    • Elucidation of free radical scavenging and antioxidant activity of aqueous and hydro-ethanolic extracts of moringa oleifera pods
    • Paliwal R, Sharma V, Pracheta, et al(2011d). Elucidation of free radical scavenging and antioxidant activity of aqueous and hydro-ethanolic extracts of moringa oleifera pods. Res J Pharm Technol, 4, 566-71.
    • (2011) Res J Pharm Technol , vol.4 , pp. 566-571
    • Paliwal, R.1    Sharma, V.2    Pracheta, X.3
  • 31
    • 0025108644 scopus 로고
    • Aspartate amino transferase isoenzymes
    • Panteghini M (1990). Aspartate amino transferase isoenzymes. Clin. Biochem, 23, 311-9.
    • (1990) Clin. Biochem , vol.23 , pp. 311-319
    • Panteghini, M.1
  • 32
    • 83055189826 scopus 로고    scopus 로고
    • Effect of methanolic extract of Cleome chelidonii on Drug metabolising enzymes, antioxidant status and chemomodulatory efficacy of mice
    • Parimalakrishnan S, Dey A, Manavalan R (2009). Effect of methanolic extract of Cleome chelidonii on Drug metabolising enzymes, antioxidant status and chemomodulatory efficacy of mice. J Basic App Sci, 5, 37-46.
    • (2009) J Basic App Sci , vol.5 , pp. 37-46
    • Parimalakrishnan, S.1    Dey, A.2    Manavalan, R.3
  • 33
    • 82755168371 scopus 로고    scopus 로고
    • Modulation of DMBA induced biochemical and histopathological changes by Syzygium cumini seed extract during skin carcinogenesis
    • Parmar J, Sharma P, Verma P, et al(2011). Modulation of DMBA induced biochemical and histopathological changes by Syzygium cumini seed extract during skin carcinogenesis. Int J Cur Biomed Phar Res, 1, 24-30.
    • (2011) Int J Cur Biomed Phar Res , vol.1 , pp. 24-30
    • Parmar, J.1    Sharma, P.2    Verma, P.3
  • 34
    • 33847685224 scopus 로고    scopus 로고
    • Inhibitory effects of histone deacetylase inhibitor depsipeptide on benzo(a)pyrene- and cyclophosphamide-induced genotoxicity in Swiss albino mice
    • Radhakrishnan V, Park CM, Ravikumar V, et al(2007) Inhibitory effects of histone deacetylase inhibitor depsipeptide on benzo(a)pyrene- and cyclophosphamide-induced genotoxicity in Swiss albino mice. Int J Toxicol, 26, 47-50.
    • (2007) Int J Toxicol , vol.26 , pp. 47-50
    • Radhakrishnan, V.1    Park, C.M.2    Ravikumar, V.3
  • 35
    • 34248169275 scopus 로고    scopus 로고
    • Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats
    • Ramakrishnan G, Augustine TA, Jagan S, et al(2007). Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats. Exp Oncol, 29, 39-44.
    • (2007) Exp Oncol , vol.29 , pp. 39-44
    • Ramakrishnan, G.1    Augustine, T.A.2    Jagan, S.3
  • 36
    • 84555211449 scopus 로고
    • A colorimetric method for the determination of serum glutathione oxaloacetate and glutamic- pyruvic transaminase
    • Reitman S, Franckal S (1979). A colorimetric method for the determination of serum glutathione oxaloacetate and glutamic- pyruvic transaminase. J Clin Pathol, 28, 481-90.
    • (1979) J Clin Pathol , vol.28 , pp. 481-490
    • Reitman, S.1    Franckal, S.2
  • 38
    • 76749090502 scopus 로고    scopus 로고
    • The effect of oral administration of Allium sativum extracts on lead nitrate induced toxicity in male mice
    • Sharma V, Sharma A, Kansal L (2010). The effect of oral administration of Allium sativum extracts on lead nitrate induced toxicity in male mice. Food and Chemical Toxicol, 48, 928-36.
    • (2010) Food and Chemical Toxicol , vol.48 , pp. 928-936
    • Sharma, V.1    Sharma, A.2    Kansal, L.3
  • 39
    • 83055196302 scopus 로고    scopus 로고
    • Phytochemical analysis and evaluation of antioxidant activities of hydro-ethanolic extracts of Moringa oleifera lam pods
    • Sharma V, Paliwal R, Pracheta, et al(2011). Phytochemical analysis and evaluation of antioxidant activities of hydro-ethanolic extracts of Moringa oleifera lam pods. J Pharm Res, 4, 554-7.
    • (2011) J Pharm Res , vol.4 , pp. 554-557
    • Sharma, V.1    Paliwal, R.2    Pracheta, X.3
  • 40
    • 0000118697 scopus 로고    scopus 로고
    • Alfalfa saponins and their implication in animal nutrition
    • Sen S, Makkar HPS, Becker K (1998). Alfalfa saponins and their implication in animal nutrition. J Agri Food Chem, 46, 131-40.
    • (1998) J Agri Food Chem , vol.46 , pp. 131-140
    • Sen, S.1    Makkar, H.P.S.2    Becker, K.3
  • 41
    • 33745948821 scopus 로고    scopus 로고
    • Hepatoprotective effects of Pittosporum neelgherrense Wight and Arn., a popular Indian ethnomedicine
    • Shyamal S, Latha PG, Shine VJ, et al(2006). Hepatoprotective effects of Pittosporum neelgherrense Wight&Arn., a popular Indian ethnomedicine. J Ethnopharmacol, 107, 151-5.
    • (2006) J Ethnopharmacol , vol.107 , pp. 151-155
    • Shyamal, S.1    Latha, P.G.2    Shine, V.J.3
  • 42
    • 0033661509 scopus 로고    scopus 로고
    • Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabolism antioxidant status and lipid peroxidation in mice
    • Singh RP, Padmanathi B, Rao AR, (2000). Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabolism antioxidant status and lipid peroxidation in mice. Mol Cell Biochem, 213, 99-109.
    • (2000) Mol Cell Biochem , vol.213 , pp. 99-109
    • Singh, R.P.1    Padmanathi, B.2    Rao, A.R.3
  • 43
    • 0034561538 scopus 로고    scopus 로고
    • Chemoprevention of DMBA-induced mammary carcinogenesis: Relationship between induction of phase II enzymes, effects on DMBA induced hemoglobin adducts and decrease in mammary tumor multiplicity
    • Song LL, Steven R, Lantvit MD, et al(2000). Chemoprevention of DMBA-induced mammary carcinogenesis: Relationship between induction of phase II enzymes, effects on DMBA induced hemoglobin adducts and decrease in mammary tumor multiplicity. Polycyclic Aromatic Comp, 18, 193-210.
    • (2000) Polycyclic Aromatic Comp , vol.18 , pp. 193-210
    • Song, L.L.1    Steven, R.2    Lantvit, M.D.3
  • 44
    • 0034011263 scopus 로고    scopus 로고
    • Chemoprevention of cancer
    • Sporn MB, Suh N (2000). Chemoprevention of cancer. Carcinogenesis, 21, 525-30.
    • (2000) Carcinogenesis , vol.21 , pp. 525-530
    • Sporn, M.B.1    Suh, N.2
  • 45
    • 79251580689 scopus 로고    scopus 로고
    • In vitro bioautography of different Indian medicinal plants
    • Vadlapudi V, Naidu KC (2010). In vitro bioautography of different Indian medicinal plants. Drug Invent Today, 2, 53-6.
    • (2010) Drug Invent Today , vol.2 , pp. 53-56
    • Vadlapudi, V.1    Naidu, K.C.2
  • 46
    • 0017518823 scopus 로고
    • Cholesterol methodologies: a review
    • Zak B (1977). Cholesterol methodologies: a review. Clin Chem, 23, 1201-14.
    • (1977) Clin Chem , vol.23 , pp. 1201-1214
    • Zak, B.1


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