Static and dynamic nanomechanical properties of human skin tissue using atomic force microscopy: Effect of scarring in the upper dermis

Acta Biomaterialia

Volumn 8, Issue 11, 2012, Pages 4123-4129

  Grant, C A ^a   Twigg, P C ^a   Tobin, D J ^a  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Atomic force microscopy; Creep indentation; Scar tissue; Skin; Viscoelasticity

Indexed keywords

ATOMIC FORCE MICROSCOPY; BEARINGS (MACHINE PARTS); CREEP; TISSUE; TISSUE ENGINEERING;

ATOMIC-FORCE-MICROSCOPY; BIOCHEMICAL CHANGES; CREEP INDENTATION; HUMAN SKIN; LOAD-BEARING; NANOMECHANICAL PROPERTY; SCAR TISSUES; SKIN TISSUE; STATICS AND DYNAMICS; TRAUMATIC INJURY;

VISCOELASTICITY;

COLLAGEN FIBRIL; NANOMATERIAL;

ADULT; ARTICLE; ATOMIC FORCE MICROSCOPE; ATOMIC FORCE MICROSCOPY; DENSITY; DERMIS; FORCE; HUMAN; HUMAN CELL; MALE; MICROSCOPE SLIDE; MIDDLE AGED; MOLECULAR MECHANICS; PRIORITY JOURNAL; SKIN SCAR; VISCOELASTICITY; BIOMECHANICS; CHEMISTRY; ELASTICITY; METHODOLOGY; PATHOLOGY; SCAR; ULTRASTRUCTURE; VISCOSITY;

BIOMECHANICS; CICATRIX; DERMIS; ELASTICITY; HUMANS; MALE; MICROSCOPY, ATOMIC FORCE; MIDDLE AGED; NANOSTRUCTURES; VISCOSITY;

EID: 84873957750     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.06.042     Document Type: Article

References (33)

1. Tobin DJ. Biochemistry of human skin-our brain on the outside. Chem Soc Rev 2006;35:52-67. (Pubitemid 43485013)
2. Dallon J, Sherratt J, Maini P, Ferguson M. Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair. Math Med Biol 2000;17:379-93. (Pubitemid 32185856)
3. Kwan KHL, Liu X, To MKT, Yeung KWK, Ho C-m, Wong KKY. Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing. Nanomed: nanotechnol, biol med 2011;7:497-504.
4. Bock O, Schmid-Ott G, Malewski P, Mrowietz U. Quality of life of patients with keloid and hypertrophic scarring. Arch Dermatol Res 2006;297:433-8.
5. Verhaegen PDHM, VanZuijlen PPM, Pennings NM, VanMarle J, Niessen FB, VanDerHorst CMAM, et al. Differences in collagen architecture between keloid, hypertrophic scar, normotrophic scar, and normal skin: An objective histopathological analysis. Wound Repair Regen 2009;17:649-56.
6. Ferguson MWJ, O'Kane S. Scar-free healing: From embryonic mechanisms to adult therapeutic intervention. Philos Trans R Soc Lond B: Biol Sci 2004;359:839-50. (Pubitemid 38673751)
7. Adzick NS, Lorenz HP. Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair. Ann Surg 1994;220:10-8. (Pubitemid 24205841)
8. Buchanan EP, Longaker MT, Lorenz HP. Fetal skin wound healing. Adv Clin Chem 2009;48:137-61.
9. Tang W, Bhushan B. Adhesion, friction and wear characterization of skin and skin cream using atomic force microscope. Colloids Surf B 2010;76:1-15.
10. Yuan Y, Verma R. Measuring microelastic properties of stratum corneum. Colloids Surf B 2006;48:6-12.
11. Geerligs M, van Breemen L, Peters G, Ackermans P, Baaijens F, Oomens C. In vitro indentation to determine the mechanical properties of epidermis. J Biomech 2011;44:1176-81.
12. Crichton ML, Donose BC, Chen X, Raphael AP, Huang H, Kendall MAF. The viscoelastic, hyperelastic and scale dependent behaviour of freshly excised individual skin layers. Biomaterials 2011;32:4670-81.
13. Fan ZF, Smith P, Rauch F, Harris GF. Nanoindentation as a means for distinguishing clinical type of osteogenesis imperfecta. Composites Part B 2007;38:411-5. (Pubitemid 46149465)
14. Stolz M, Gottardi R, Raiteri R, Miot S, Martin I, Imer R, et al. Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nano 2009;4:186-92.
15. Zhong SP, Zhang YZ, Lim CT. Tissue scaffolds for skin wound healing and dermal reconstruction. Wiley Interdisciplinary Rev: Nanomed Nanobiotechnol 2010;2:510-25.
16. Hutter JL, Bechhoefer J. Calibration of atomic-Force Microscope tips. Rev Sci Instrum 1993;64:1868-73.
17. Cumming BD, McElwain DLS, Upton Z. A mathematical model of wound healing and subsequent scarring. J R Soc Interface 2010;7:19-34.
18. Grant CA, Thomson NH, Savage MD, Woon HW, Greig D. Surface characterisation and biomechanical analysis of the sclera by atomic force microscopy. J Mech Behav Biomed Mater 2011;4:535-40.
19. Silver FH, Kato YP, Ohno M, Wasserman AJ. Analysis of mammalian connective tissue: relationship between hierarchical structures and mechanical properties. J Long Term Eff Med Implants 1992;2:165-98. (Pubitemid 23618544)
20. Jor JWY, Nielsen PMF, Nash MP, Hunter PJ. Modelling collagen fibre orientation in porcine skin based upon confocal laser scanning microscopy. Skin Res Technol 2011;17:149-59.
21. Butt H-J, Cappella B, Kappl M. Force measurements with the atomic force microscope: Technique, interpretation and applications. Surf Sci Rep 2005;59:1-152. (Pubitemid 41594664)
22. Withers JR, Aston DE. Nanomechanical measurements with AFM in the elastic limit. Adv in Colloid Interface Sci 2006;120:57-67. (Pubitemid 44208722)
23. Thurner PJ. Atomic force microscopy and indentation force measurement of bone. Wiley Interdisciplinary Rev: Nanomed Nanobiotechnol 2009;1:624-49.
24. Chow M-J, Zhang Y. Changes in the mechanical and biochemical properties of aortic tissue due to cold storage. J Surg Res 2011;171:434-42.
25. Foutz TL, Stone EA, Abrams CF Jr. Effects of freezing on mechanical properties of rat skin. Am J Vet Res 1992;53:788-92.
26. Moon DK, Woo SLY, Takakura Y, Gabriel MT, Abramowitch SD. The effects of refreezing on the viscoelastic and tensile properties of ligaments. J Biomech 2006;39:1153-7.
27. Nazarian A, Hermannsson BJ, Muller J, Zurakowski D, Snyder BD. Effects of tissue preservation on murine bone mechanical properties. J Biomech 2009;42:82-6 [Epub 2008 Dec 9].
28. Szarko M, Muldrew K, Bertram JE. Freeze-thaw treatment effects on the dynamic mechanical properties of articular cartilage. BMC Musculoskel Disord 2010;11:231-8.
29. Clark JA, Cheng JCY, Leung KS. Mechanical properties of normal skin and hypertrophic scars. Burns 1996;22:443-6. (Pubitemid 26306105)
30. Seehra GP, Silver FH. Viscoelastic properties of acid-And alkaline-treated human dermis: A correlation between total surface charge and elastic modulus. Skin Res Technol 2006;12:190-8. (Pubitemid 43985013)
31. Han L, Frank Eliot H, Greene Jacqueline J, Lee H-Y, Hung H-Hwa K, Grodzinsky Alan J, et al. Time-dependent nanomechanics of cartilage. Biophys J 2011;100:1846-54.
32. Grant CA, Phillips MA, Thomson NH. Dynamic mechanical analysis of collagen fibrils at the nanoscale. J Mech Behav Biomed Mater 2012;5:165-70.
33. Ventre M, Mollica F, Netti PA. The effect of composition and microstructure on the viscoelastic properties of dermis. J Biomech 2009;42:430-5.