Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 7, Issue 4, 2011, Pages 497-504

  Kwan, Karen H L ^a   Liu, Xuelai ^a   To, Michael K T ^a   Yeung, Kelvin W K ^a   Ho, Chi ming ^b   Wong, Kenneth K Y ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Collagen organization; Healing; Silver nanoparticles; Tensile strength

Indexed keywords

ALIGNMENT; CELL CULTURE; COLLAGEN; DEPOSITION; METAL NANOPARTICLES; SCANNING ELECTRON MICROSCOPY; TENSILE STRENGTH;

COLLAGEN DEPOSITION; COLLAGEN ORGANIZATIONS; ENHANCED DIFFERENTIATIONS; HEALING; IMMUNOHISTOCHEMICAL STAINING; QUANTITATIVE ASSAY; SILVER NANOPARTICLES (AGNPS); WOUND HEALING PROCESS;

SILVER NANOPARTICLES;

COLLAGEN; COLLAGEN FIBER; SILVER NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; HUMAN; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PROTEIN STRUCTURE; QUANTITATIVE ASSAY; SCANNING ELECTRON MICROSCOPY; TENSILE STRENGTH; WOUND HEALING;

EID: 79960735142     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.01.003     Document Type: Article

References (34)

1. Midwood K.S., Williams L.V., Schwarzbauer J.E. Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol 2004, 36:1031-1037.
2. Singer A.J., Clark R.A. Cutaneous wound healing. N Engl J Med 1999, 341:738-746.
3. Fratzl P., Misof K., Zizak I., Rapp G., Amenitsch H., Bernstorff S. Fibrillar structure and mechanical properties of collagen. J Struct Biol 1998, 122:119-122.
4. Lee P.Y., Chesnoy S., Huang L. Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice. J Invest Dermatol 2004, 123:791-798.
5. Tian J., Wong K.K., Ho C.M., Lok C.N., Yu W.Y., Che C.M., et al. Topical delivery of silver nanoparticles promotes wound healing. ChemMedChem 2007, 2:129-136.
6. Liu X., Lee P.Y., Ho C.M., Lui V.C., Chen Y., Che C.M., et al. Silver nanoparticles mediate differential responses in keratinocytes and fibroblasts during skin wound healing. ChemMedChem 2010, 5:468-475.
7. Martin P. Wound healing: aiming for perfect skin regeneration. Science 1997, 276:75-81.
8. Saap L.J., Falanga V. Debridement performance index and its correlation with complete closure of diabetic foot ulcers. Wound Repair Regen 2002, 10:354-359.
9. Myers S.R., Partha V.N., Soranzo C., Price R.D., Navsaria H.A. Hyalomatrix: a temporary epidermal barrier, hyaluronan delivery, and neodermis induction system for keratinocyte stem cell therapy. Tissue Eng 2007, 13:2733-2741.
10. Medugorac I. Myocardial collagen in different forms of heart hypertrophy in the rat. Res Exp Med (Berl) 1980, 177:201-211.
11. Lopes J.D., Gomes R.A., Hial V., Lopes I.C., Reis M.A., Teixeira Vde P. Correlations between the collagen content of the human left ventricular myocardium, measured by biochemical and morphometric methods. Arq Bras Cardiol 2002, 79:10-19.
12. Orgel J.P., Miller A., Irving T.C., Fischetti R.F., Hammersley A.P., Wess T.J. The in situ supermolecular structure of type I collagen. Structure 2001, 9:1061-1069.
13. Puxkandl R., Zizak I., Paris O., Keckes J., Tesch W., Bernstorff S., et al. Viscoelastic properties of collagen: Synchrotron radiation investigations and structural model. Philos Trans R Soc Lond B Biol Sci 2002, 357:191-197.
14. Bello Y.M., Falabella A.F., Eaglstein W.H. Tissue-engineered skin. Current status in wound healing. Am J Clin Dermatol 2001, 2:305-313.
15. Nakagawa H., Akita S., Fukui M., Fujii T., Akino K. Human mesenchymal stem cells successfully improve skin-substitute wound healing. Br J Dermatol 2005, 153:29-36.
16. DeCarbo W.T. Special segment: soft tissue matrices-Apligraf bilayered skin substitute to augment healing of chronic wounds in diabetic patients. Foot Ankle Spec 2009, 2:299-302.
17. Burke J.F., Yannas I.V., Quinby W.C.J., Bondoc C.C., Jung W.K. Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann Surg 1981, 194:413-428.
18. Lorenz H.P., Whitby D.J., Longaker M.T., Adzick N.S. Fetal wound healing. The ontogeny of scar formation in the non-human primate. Ann Surg 1993, 217:391-396.
19. Bullard K.M., Cass D.L., Banda M.J., Adzick N.S. Transforming growth factor beta-1 decreases interstitial collagenase in healing human fetal skin. J Pediatr Surg 1997, 32:1023-1027.
20. Adzick N.S., Lorenz H.P. Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair. Ann Surg 1994, 220:10-18.
21. Liechty K.W., Adzick N.S., Crombleholme T.M. Diminished INTERLEUKIN 6 (IL-6) production during scarless human fetal wound repair. Cytokine 2000, 12:671-676.
22. Fu X., Li X., Cheng B., Chen W., Sheng Z. Engineered growth factors and cutaneous wound healing: success and possible questions in the past 10 years. Wound Repair Regen 2005, 13:122-130.
23. Malinda K.M., Sidhu G.S., Mani H., Banaudha K., Maheshwari R.K., Goldstein A.L., et al. Thymosin beta 4 accelerates wound healing. J Invest Dermatol 1999, 113:364-368.
24. Montesano R., Orci L. Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. Proc Natl Acad Sci U S A 1988, 85:4894-4897.
25. Werner S., Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003, 83:835-870.
26. Knighton D.R., Silver I.A., Hunt T.K. Regulation of wound-healing angiogenesis-effect of oxygen gradients and inspired oxygen concentration. Surgery 1981, 90:262-270.
27. Chandan K.S., Savita K., Gayle G., Debasis B., Manashi B., Sashwati R. Oxygen, oxidants, and antioxidants in wound healing. Ann N Y Acad Sci 2002, 957:239-249.
28. Lu W.W., Ip W.Y., Jing W.M., Holmes A.D., Chow S.P. Biomechanical properties of thin skin flap after basic fibroblast growth factor (bFGF) administration. Br J Plast Surg 2000, 53:225-229.
29. Danielson K.G., Baribault H., Holmes D.F., Graham H., Kadler K.E., Iozzo R.V. Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J Cell Biol 1997, 136:729-743.
30. Smith M.J., Haltom J.D., Gainor B.J. Effects of anticoagulation on wound healing using a tensile test. Orthopedics 2008, 31:373-377.
31. Chakravarti S., Magnuson T., Lass J.H., Jepsen K.J., LaMantia C., Carroll H. Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol 1998, 141:1277-1286.
32. Dombi G.W., Haut R.C., Sullivan W.G. Correlation of high-speed tensile strength with collagen content in control and lathyritic rat skin. J Surg Res 1993, 54:21-28.
33. Kadler K.E., Holmes D.F., Trotter J.A., Chapman J.A. Collagen fibril formation. Biochem J 1996, 316(Pt 1):1-11.
34. Sasaki N., Odajima S. Elongation mechanism of collagen fibrils and force-strain relations of tendon at each level of structural hierarchy. J Biomechanic 1996, 29:1131-1136.